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The map label for this gene is obgE

Identifier: 190570656

GI number: 190570656

Start: 211223

End: 212236

Strand: Reverse

Name: obgE

Synonym: WPa_0204

Alternate gene names: 190570656

Gene position: 212236-211223 (Counterclockwise)

Preceding gene: 190570657

Following gene: 190570654

Centisome position: 14.32

GC content: 35.5

Gene sequence:

>1014_bases
ATGGACTTCATAGACGAAGTTAAATTATATTTAAAAGCAGGTGATGGTGGCGATGGCTGCGCAAGTTTTCGTCGAGAAAA
ATTCGTTGAATTTGGTGGCCCAAACGGTGGTAATGGGGGCAAGGGAGGAGACATAATTTTCATCAGTGATGCAAATCTCA
ACACTTTGCTTAATTTTCGTTGTCGAAGACATATTAAAGCAAGTAGTGGAAAAAGTGGTACGAGTAGAGATAGATCTGGC
ACGGCAGGAAAAGATATTATACTTAAAGTTCCAGTTGGTACACAAATAATAGATGAAGAAAGTGAGGAAGTGATAGTAGA
TCTTGATAAACCCGACATGGAATTTCAAGTAGTACAAGGTGGAAAAGGTGGACTTGGAAATACTAACTTTAAATCTTCCA
CCAATAGGGCACCAAGGCATTTTACTCATGGTCAGCCTGGTGAGGAAAGAAACATAGTATTGAAGCTAAAAGTTTTATCT
GATGTTGGCATTATTGGTATGCCAAATGTAGGTAAATCTAAATTTTTAACCCGCTGCTCGAATTCTGATACGAAAGTAGG
CGATTATGAATTTACTACTATAAGACCACATTTAGGTGTAGCAAAAGTGGATTATAGCGAAATTGTAATAGCAGATATTC
CTGGAATAATCGCTGATGCTCATCTTGGAGTTGGGCTCGGACACAAATTTTTAAAGCACATAGAAAGGTGCAAAATTTTA
CTGCATTTAATTGATGTAACTCACGATGAAATTATTTCAGCTTATAATTGTACGCATAATGAACTGAAGCTTTACAATAG
CGATCTTGTTGAAAAAGAGGAAATTGTAGTGTTAAATAAATGTGACTTATTGGAAGAAACAGAAATTCTTGAGAAGAAGA
ATCATTTAGCCAATTATCTTGATAGAGAAGTACTGTGTTTATCAATTGACGATGATTTACAGCCCATTCTGAGGTTGTTA
AATGAAAAAGTGAAAACTAAGGAAATTAATGTATATGATCCTTTTAAGATGTGA

Upstream 100 bases:

>100_bases
CTGGCTCGCTGTCGCGTTCTGATAGGCTTGCAAAGTATAATGAATTAATGAGAATAGAAAGTTCATTAGGAGAAAATGCT
AAATATTATTGTGGGTTAGC

Downstream 100 bases:

>100_bases
ATTTTTTATTTGACAATCAAAGTCTGGATTCCAGTGGGTAATTTTCCACAGTTGTCTGCATTTTTTGTTCCACAACTTAT
CTTTTTTTCGGCTTGTGCCA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MDFIDEVKLYLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGDIIFISDANLNTLLNFRCRRHIKASSGKSGTSRDRSG
TAGKDIILKVPVGTQIIDEESEEVIVDLDKPDMEFQVVQGGKGGLGNTNFKSSTNRAPRHFTHGQPGEERNIVLKLKVLS
DVGIIGMPNVGKSKFLTRCSNSDTKVGDYEFTTIRPHLGVAKVDYSEIVIADIPGIIADAHLGVGLGHKFLKHIERCKIL
LHLIDVTHDEIISAYNCTHNELKLYNSDLVEKEEIVVLNKCDLLEETEILEKKNHLANYLDREVLCLSIDDDLQPILRLL
NEKVKTKEINVYDPFKM

Sequences:

>Translated_337_residues
MDFIDEVKLYLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGDIIFISDANLNTLLNFRCRRHIKASSGKSGTSRDRSG
TAGKDIILKVPVGTQIIDEESEEVIVDLDKPDMEFQVVQGGKGGLGNTNFKSSTNRAPRHFTHGQPGEERNIVLKLKVLS
DVGIIGMPNVGKSKFLTRCSNSDTKVGDYEFTTIRPHLGVAKVDYSEIVIADIPGIIADAHLGVGLGHKFLKHIERCKIL
LHLIDVTHDEIISAYNCTHNELKLYNSDLVEKEEIVVLNKCDLLEETEILEKKNHLANYLDREVLCLSIDDDLQPILRLL
NEKVKTKEINVYDPFKM
>Mature_337_residues
MDFIDEVKLYLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGDIIFISDANLNTLLNFRCRRHIKASSGKSGTSRDRSG
TAGKDIILKVPVGTQIIDEESEEVIVDLDKPDMEFQVVQGGKGGLGNTNFKSSTNRAPRHFTHGQPGEERNIVLKLKVLS
DVGIIGMPNVGKSKFLTRCSNSDTKVGDYEFTTIRPHLGVAKVDYSEIVIADIPGIIADAHLGVGLGHKFLKHIERCKIL
LHLIDVTHDEIISAYNCTHNELKLYNSDLVEKEEIVVLNKCDLLEETEILEKKNHLANYLDREVLCLSIDDDLQPILRLL
NEKVKTKEINVYDPFKM

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=307, Percent_Identity=38.4364820846906, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI111955139, Length=295, Percent_Identity=33.8983050847458, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI111955063, Length=127, Percent_Identity=39.3700787401575, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI58761500, Length=137, Percent_Identity=31.3868613138686, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789574, Length=307, Percent_Identity=47.557003257329, Blast_Score=256, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17508313, Length=329, Percent_Identity=34.6504559270517, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17552324, Length=346, Percent_Identity=28.6127167630058, Blast_Score=137, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6321962, Length=201, Percent_Identity=32.8358208955224, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319281, Length=98, Percent_Identity=33.6734693877551, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20129375, Length=308, Percent_Identity=37.3376623376623, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24585318, Length=248, Percent_Identity=37.5, Blast_Score=151, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_WOLPP (B3CNP2)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001975014.1
- EnsemblBacteria:   EBWOLT00000000921
- GeneID:   6385626
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_0204
- GeneTree:   EBGT00050000031118
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 37332; Mature: 37332

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFIDEVKLYLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGDIIFISDANLNTLLNFR
CCHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
CRRHIKASSGKSGTSRDRSGTAGKDIILKVPVGTQIIDEESEEVIVDLDKPDMEFQVVQG
HHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCEEEEEEC
GKGGLGNTNFKSSTNRAPRHFTHGQPGEERNIVLKLKVLSDVGIIGMPNVGKSKFLTRCS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCCCHHHHHHHCC
NSDTKVGDYEFTTIRPHLGVAKVDYSEIVIADIPGIIADAHLGVGLGHKFLKHIERCKIL
CCCCCCCCEEEEEECCCCCEEEECCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHH
LHLIDVTHDEIISAYNCTHNELKLYNSDLVEKEEIVVLNKCDLLEETEILEKKNHLANYL
HHHHHCCHHHHHHHHCCCCHHEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
DREVLCLSIDDDLQPILRLLNEKVKTKEINVYDPFKM
CCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure
MDFIDEVKLYLKAGDGGDGCASFRREKFVEFGGPNGGNGGKGGDIIFISDANLNTLLNFR
CCHHHEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
CRRHIKASSGKSGTSRDRSGTAGKDIILKVPVGTQIIDEESEEVIVDLDKPDMEFQVVQG
HHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCEEEEEEC
GKGGLGNTNFKSSTNRAPRHFTHGQPGEERNIVLKLKVLSDVGIIGMPNVGKSKFLTRCS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEECCCCCHHHHHHHCC
NSDTKVGDYEFTTIRPHLGVAKVDYSEIVIADIPGIIADAHLGVGLGHKFLKHIERCKIL
CCCCCCCCEEEEEECCCCCEEEECCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHH
LHLIDVTHDEIISAYNCTHNELKLYNSDLVEKEEIVVLNKCDLLEETEILEKKNHLANYL
HHHHHCCHHHHHHHHCCCCHHEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
DREVLCLSIDDDLQPILRLLNEKVKTKEINVYDPFKM
CCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA