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The map label for this gene is 18977757

Identifier: 18977757

GI number: 18977757

Start: 1299303

End: 1299893

Strand: Direct

Name: 18977757

Synonym: PF1385

Alternate gene names: NA

Gene position: 1299303-1299893 (Clockwise)

Preceding gene: 18977756

Following gene: 18977758

Centisome position: 68.09

GC content: 37.06

Gene sequence:

>591_bases
ATGTCAAAGCATGAGCTAATGAAAAAGCTAGAAGAAAAAATACTCACCTGTAAAAAATGCCCATTGTGGAGGCTAAGAAC
TAATCCCGTTCCCGGGTATGGAAATTATGACGCAAAAATAATGTTCATTGGAGAAGCCCCAGGGTACTGGGAAGATCAAA
AAGGGTTACCATTTGTTGGAAAAGCTGGAAAAGTCTTAGATGAACTATTAGATGGGATTGGACTAACAAGAGAAGATGTT
TATATAACAAATGTGGTTAAATGTAGGCCACCAAACAATAGAGATCCGACAGAAGAAGAAATAAAGGCATGCTCCCCATA
TCTTGATCAACAGATAGATATTATAAAGCCAAAGGTTATCGTTACATTAGGAAGGCATTCCACCAATTACATCCTCAAAA
AATTTGGATTTGATCTTGAGCCAATAAGCAAAATTCATGGGAAAGTCTTCAAGGCAAAAACACTTTTTGGTACTCTTTAT
ATCTTCCCAACATATCATCCAGCAGTGGCCCTTTATAGACCTCAACTAAAGGAGGAACTAAAGCAGGATTTTGACATCCT
AAAAAGCTTGTTAGAAAAACTAGGGATTTAG

Upstream 100 bases:

>100_bases
AGATGACTATGAGAAAGGCTACTACACTGCCTGGGTAGAATTACTGCAAGCTTATCTCTCTCAAGCACGGCTACAACTCA
AAGAGAGAAAAGGTGATTAA

Downstream 100 bases:

>100_bases
GCAATCGCCGAAATATTTATATTTGACCAGGAAAATATAACTTCATGCTTGAAAAGGAAAAGAAAATCTTGGCAAAAAGA
ATTGCTGGTGAGATTGTTTT

Product: DNA polymerase

Products: diphosphate; DNAn+1

Alternate protein names: Uracil-DNA Glycosylase; Phage SPO1 DNA Polymerase-Like Protein; DNA Polymerase; DNA Polymerase Bacteriophage-Type; Uracil DNA Glycosylase Superfamily Protein; DNA-Directed DNA Polymerase; Phage Spo1 DNA Polymerase-Related Protein; DNA Polymerase-Related Protein Bacteriophage-Type; DNA Polymerase-Related Protein; Uracil-DNA Glycosylase-Like Protein; Uracil-DNA Glycosylase Family 4 Protein; Bacteriophage-Related DNA Polymerase; Uracil DNA Glycosylase; Phage SPO1 DNA Polymerase Domain-Containing Protein; Uracil-DNA Glycosylase Phage-Related Protein; Uracil-DNA Glycosylase Superfamily Protein; Phage Shock Protein E; DNA Polymerase Domain-Containing Protein; Phage DNA Polymerase; C-Terminal Part Of DNA Polymerase Bacteriophage-Type; Phage Spo1 DNA Polymerase Domain Protein; Phage Related DNA Polymerase; DNA Glycosylase; Uracil-DNA Glycosylase-Related Protein; Phage SpO1 DNA Polymerase-Related Protein; N-Terminus Of Phage SPO1 DNA Polymerase; Bacteriophage-Type DNA Polymerase; Phage DNA Polymerase-Related Protein

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSKHELMKKLEEKILTCKKCPLWRLRTNPVPGYGNYDAKIMFIGEAPGYWEDQKGLPFVGKAGKVLDELLDGIGLTREDV
YITNVVKCRPPNNRDPTEEEIKACSPYLDQQIDIIKPKVIVTLGRHSTNYILKKFGFDLEPISKIHGKVFKAKTLFGTLY
IFPTYHPAVALYRPQLKEELKQDFDILKSLLEKLGI

Sequences:

>Translated_196_residues
MSKHELMKKLEEKILTCKKCPLWRLRTNPVPGYGNYDAKIMFIGEAPGYWEDQKGLPFVGKAGKVLDELLDGIGLTREDV
YITNVVKCRPPNNRDPTEEEIKACSPYLDQQIDIIKPKVIVTLGRHSTNYILKKFGFDLEPISKIHGKVFKAKTLFGTLY
IFPTYHPAVALYRPQLKEELKQDFDILKSLLEKLGI
>Mature_195_residues
SKHELMKKLEEKILTCKKCPLWRLRTNPVPGYGNYDAKIMFIGEAPGYWEDQKGLPFVGKAGKVLDELLDGIGLTREDVY
ITNVVKCRPPNNRDPTEEEIKACSPYLDQQIDIIKPKVIVTLGRHSTNYILKKFGFDLEPISKIHGKVFKAKTLFGTLYI
FPTYHPAVALYRPQLKEELKQDFDILKSLLEKLGI

Specific function: Unknown

COG id: COG1573

COG function: function code L; Uracil-DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.7

Molecular weight: Translated: 22467; Mature: 22335

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHELMKKLEEKILTCKKCPLWRLRTNPVPGYGNYDAKIMFIGEAPGYWEDQKGLPFVG
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
KAGKVLDELLDGIGLTREDVYITNVVKCRPPNNRDPTEEEIKACSPYLDQQIDIIKPKVI
CHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHCHHHHCCHHHCCCEEE
VTLGRHSTNYILKKFGFDLEPISKIHGKVFKAKTLFGTLYIFPTYHPAVALYRPQLKEEL
EEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHCHHHHHHH
KQDFDILKSLLEKLGI
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKHELMKKLEEKILTCKKCPLWRLRTNPVPGYGNYDAKIMFIGEAPGYWEDQKGLPFVG
CHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCC
KAGKVLDELLDGIGLTREDVYITNVVKCRPPNNRDPTEEEIKACSPYLDQQIDIIKPKVI
CHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHCHHHHCCHHHCCCEEE
VTLGRHSTNYILKKFGFDLEPISKIHGKVFKAKTLFGTLYIFPTYHPAVALYRPQLKEEL
EEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHCHHHHHHH
KQDFDILKSLLEKLGI
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA