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The map label for this gene is fabF [H]

Identifier: 189499163

GI number: 189499163

Start: 174339

End: 175583

Strand: Reverse

Name: fabF [H]

Synonym: Cphamn1_0178

Alternate gene names: 189499163

Gene position: 175583-174339 (Counterclockwise)

Preceding gene: 189499164

Following gene: 189499162

Centisome position: 6.42

GC content: 52.37

Gene sequence:

>1245_bases
ATGGGTCAGGAACGCAAACGCATTGTTGTTACCGGTATAGGGGTGTTATCTCCTGTCGGTCTGTCAAAGGAAGAACTCAA
AGCATCCCTTTATCAGGGAAAAAGCGGTGCTGCGCCCATAACCTATTTTGACACGAACGGCTTTTCAACTCGTTTTGCCT
GTGAATTGAAAGGGTTCAAGGCTGAGGACTATATGGATACCAAATCCTCCTCACGCATGGACCCCTTCAGTCAGTATGCC
GTCATAGCTGCTGAGCAGGCCCTGAAGGATTCCTGTCTTGACCTTTCCTCAATCGATCCCGCGAGAATTGGTGTCGTTCA
CGGATCAGGAACCGGCGGCATGACCATACATGACGCACAGATGCGGGTATTTCTCGAAAGAGGGCCCCGCAGAATAAGCC
CGTTTTTCATCCCTATGCTTATTCCTGACATCGCTGCCGGACAGATCTCGATGAGGAACAAGTTGATGGGACCGAACTAT
GCCACTGCCTCGGCATGCGCCACTTCCCTGCACGCAATTATAGACGCATGGATGCTTCTTCAGCTCGACATGGCAGACTA
TATGGTCTGTGGTGGTTCAGAAGCCGCTATCACGCCAATGAGCGTCGGAGGGTTCAACGCCGCAAGGGCGCTGTCAACGC
GCAATGATGATCCTGAAACCGCATCACGGCCTTACGACAGGGACCGGGACGGCTTCGTAATGGGAGAAGGCGCAGGCTCT
CTGATCCTGGAAACACTTGAGTCAGCGCAGTCGCGCGGGGCCAAAATATACGGCGAACTTGCCGGTGTCGGCGCTTCAGC
AGATGCCCATCATCTCACTGCCCCCCATCCGGAAGGTGCGGGCGCATTAAACGCCATGAAAAGCGCTCTCGCTCAAGCAG
GGATTACGCCTGAAGCTATCGACTATGTCAATACACATGGCACGGCCACACCGCTTGGCGATTTAGCCGAGCTCAAAGCC
CTCAGCAAGCTCTTCGGTGATCACGCAAAAAAAATCAGCATCAGCTCGACCAAATCAATGACAGGTCATCTGCTCGGCGC
TGCAGGTGTCGTAGAGTCAATTGCCTGTCTTCTTGCACTGGAAAGTCAGGTTGTGCCTCCTACGATCAATATCGAGAACC
TTGACCCTGAAGTTGATCTGGATGTCACTCCCAACACGCCTACAGAACGAAAAATCGACTACGTTCTCAACAACGGCTTT
GGCTTTGGCGGTCATAACGCTACGCTTATTTTCAAAAAAATATAG

Upstream 100 bases:

>100_bases
AAAAATCAGCACTGTTCAGCAGGCGATAGATTACATCGTGAACAACAAATAATTTCCCTGCGCAATCAGCATCAAGCAGG
CTTAACGTCAAACAAGTGAA

Downstream 100 bases:

>100_bases
GTATCCGCAAAACATCTCCTGCATATGGAGAAGCTCTGGCAAAAACTCAGCTCATTAGCCTTCAATCGCCCTCAAAGCCA
TGAGCAGTCTGAAACCGGAC

Product: 3-oxoacyl-(acyl-carrier-protein) synthase 2

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MGQERKRIVVTGIGVLSPVGLSKEELKASLYQGKSGAAPITYFDTNGFSTRFACELKGFKAEDYMDTKSSSRMDPFSQYA
VIAAEQALKDSCLDLSSIDPARIGVVHGSGTGGMTIHDAQMRVFLERGPRRISPFFIPMLIPDIAAGQISMRNKLMGPNY
ATASACATSLHAIIDAWMLLQLDMADYMVCGGSEAAITPMSVGGFNAARALSTRNDDPETASRPYDRDRDGFVMGEGAGS
LILETLESAQSRGAKIYGELAGVGASADAHHLTAPHPEGAGALNAMKSALAQAGITPEAIDYVNTHGTATPLGDLAELKA
LSKLFGDHAKKISISSTKSMTGHLLGAAGVVESIACLLALESQVVPPTINIENLDPEVDLDVTPNTPTERKIDYVLNNGF
GFGGHNATLIFKKI

Sequences:

>Translated_414_residues
MGQERKRIVVTGIGVLSPVGLSKEELKASLYQGKSGAAPITYFDTNGFSTRFACELKGFKAEDYMDTKSSSRMDPFSQYA
VIAAEQALKDSCLDLSSIDPARIGVVHGSGTGGMTIHDAQMRVFLERGPRRISPFFIPMLIPDIAAGQISMRNKLMGPNY
ATASACATSLHAIIDAWMLLQLDMADYMVCGGSEAAITPMSVGGFNAARALSTRNDDPETASRPYDRDRDGFVMGEGAGS
LILETLESAQSRGAKIYGELAGVGASADAHHLTAPHPEGAGALNAMKSALAQAGITPEAIDYVNTHGTATPLGDLAELKA
LSKLFGDHAKKISISSTKSMTGHLLGAAGVVESIACLLALESQVVPPTINIENLDPEVDLDVTPNTPTERKIDYVLNNGF
GFGGHNATLIFKKI
>Mature_413_residues
GQERKRIVVTGIGVLSPVGLSKEELKASLYQGKSGAAPITYFDTNGFSTRFACELKGFKAEDYMDTKSSSRMDPFSQYAV
IAAEQALKDSCLDLSSIDPARIGVVHGSGTGGMTIHDAQMRVFLERGPRRISPFFIPMLIPDIAAGQISMRNKLMGPNYA
TASACATSLHAIIDAWMLLQLDMADYMVCGGSEAAITPMSVGGFNAARALSTRNDDPETASRPYDRDRDGFVMGEGAGSL
ILETLESAQSRGAKIYGELAGVGASADAHHLTAPHPEGAGALNAMKSALAQAGITPEAIDYVNTHGTATPLGDLAELKAL
SKLFGDHAKKISISSTKSMTGHLLGAAGVVESIACLLALESQVVPPTINIENLDPEVDLDVTPNTPTERKIDYVLNNGFG
FGGHNATLIFKKI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=43.1325301204819, Blast_Score=319, Evalue=3e-87,
Organism=Homo sapiens, GI223972627, Length=167, Percent_Identity=49.7005988023952, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI41872631, Length=367, Percent_Identity=24.7956403269755, Blast_Score=96, Evalue=8e-20,
Organism=Escherichia coli, GI1787337, Length=411, Percent_Identity=50.1216545012166, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1788663, Length=419, Percent_Identity=40.3341288782816, Blast_Score=262, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI71983541, Length=413, Percent_Identity=34.6246973365617, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI71983535, Length=259, Percent_Identity=39.3822393822394, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI212642053, Length=358, Percent_Identity=25.4189944134078, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=264, Percent_Identity=26.5151515151515, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=445, Percent_Identity=34.3820224719101, Blast_Score=238, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24644341, Length=416, Percent_Identity=42.5480769230769, Blast_Score=311, Evalue=5e-85,
Organism=Drosophila melanogaster, GI221330659, Length=371, Percent_Identity=25.0673854447439, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI19920632, Length=368, Percent_Identity=24.1847826086957, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24581345, Length=427, Percent_Identity=23.4192037470726, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43754; Mature: 43623

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQERKRIVVTGIGVLSPVGLSKEELKASLYQGKSGAAPITYFDTNGFSTRFACELKGFK
CCCCCCEEEEEECHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCC
AEDYMDTKSSSRMDPFSQYAVIAAEQALKDSCLDLSSIDPARIGVVHGSGTGGMTIHDAQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEHHH
MRVFLERGPRRISPFFIPMLIPDIAAGQISMRNKLMGPNYATASACATSLHAIIDAWMLL
HHHHHHCCCCCCCCEEHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
QLDMADYMVCGGSEAAITPMSVGGFNAARALSTRNDDPETASRPYDRDRDGFVMGEGAGS
HCCCHHEEEECCCCCEECEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHH
LILETLESAQSRGAKIYGELAGVGASADAHHLTAPHPEGAGALNAMKSALAQAGITPEAI
HHHHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
DYVNTHGTATPLGDLAELKALSKLFGDHAKKISISSTKSMTGHLLGAAGVVESIACLLAL
HHHCCCCCCCCCHHHHHHHHHHHHHCCHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ESQVVPPTINIENLDPEVDLDVTPNTPTERKIDYVLNNGFGFGGHNATLIFKKI
HCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
GQERKRIVVTGIGVLSPVGLSKEELKASLYQGKSGAAPITYFDTNGFSTRFACELKGFK
CCCCCEEEEEECHHHCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCC
AEDYMDTKSSSRMDPFSQYAVIAAEQALKDSCLDLSSIDPARIGVVHGSGTGGMTIHDAQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEHHH
MRVFLERGPRRISPFFIPMLIPDIAAGQISMRNKLMGPNYATASACATSLHAIIDAWMLL
HHHHHHCCCCCCCCEEHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
QLDMADYMVCGGSEAAITPMSVGGFNAARALSTRNDDPETASRPYDRDRDGFVMGEGAGS
HCCCHHEEEECCCCCEECEEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHH
LILETLESAQSRGAKIYGELAGVGASADAHHLTAPHPEGAGALNAMKSALAQAGITPEAI
HHHHHHHHHHHCCCEEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
DYVNTHGTATPLGDLAELKALSKLFGDHAKKISISSTKSMTGHLLGAAGVVESIACLLAL
HHHCCCCCCCCCHHHHHHHHHHHHHCCHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
ESQVVPPTINIENLDPEVDLDVTPNTPTERKIDYVLNNGFGFGGHNATLIFKKI
HCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]