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The map label for this gene is hemH [H]

Identifier: 189499119

GI number: 189499119

Start: 126804

End: 127823

Strand: Direct

Name: hemH [H]

Synonym: Cphamn1_0128

Alternate gene names: 189499119

Gene position: 126804-127823 (Clockwise)

Preceding gene: 189499118

Following gene: 189499120

Centisome position: 4.63

GC content: 51.57

Gene sequence:

>1020_bases
ATGTTATCCATTACTCAATCACATCCGCTGAGTGCATTCCGCCAGAGCATTATGCATAAACGTATTGCAGTTATCCTTGC
TGCCCACGGAGAGGCTGAAACAGCTGGTTTTTTTGATAATTTTTCCATGACACGCCATACTCTTGCCCATGCGGGCGAGG
TGATGAACCTTCCGGTTCCTCTGCAACTGATGATATCGGTTGCGGGCGGACTGAAAAACATGGTCAAGTTCAAAAAGAAA
AACTACCGCTCGCCCCAGAACAGGATCACCAGAAAGCAGGCGGCATTGCTCGCCGAAAAACTTGCCGGGCAGGCTGAGGC
CATACGCTATGACGTTCATGCTTCGTTTTTCGTGACCCCGCCTTTTGTCGAACAGATTGTCGAGCAGGTACGCGACTGTG
ATATGCTGCTGCTTATTCCGATGGCACCGATCGATAACCGGCTCATGTCGGGAAGTCTCGAAATCCTTGCTGAAAGATAC
CTGCCGCCCCGTGTCCCATCGCGTCCTCAGGTCATTTCCGGGTTCTGGAATGACCCTGGACTTCTCAACGTCTATCTTGA
CCACCTGTTTATGCACGCTGCGCCTGTACCGGGTTCCGCGCTTGTACTCGCCTTTCACGGTACACTCGAAAAGGATCAAC
GGGGAAACGAACCGGAATTCCAGACCGGTTCGAAGGAAATAGCCACGATGGCCTCAGCACTGCGAAAAGCTGTTTGCAAC
GATCCTCGCAACGGATATGAACGCGTCGAAGTCGCGTATCTCAACCATGACGTCGGCGGAACATGGTCAAGCCCATCCCT
TCAGGATATGCTCAAAAGTCTGCACAGGGAGAGCATTGCCTCCATTGAACTATTCAGTTGCGGCTATTTTTCCGATGGAA
CCGAAACAATGCTCAATGCAAGAGAACATGTTGTTGAAAGCGGCATCCGAAAAGCAGCCATCATTCCCTGTCTCAACGAT
TCAGAACCCTTTGCCGACTATCTTGCTGCAAAGGTCAGGGACGCGGTGACAGGAGCGTGA

Upstream 100 bases:

>100_bases
GTTTCGCTTTAATTTTATAAAGCCCGTATTTTCCACACATGACAGCGTTTTAATTTCAGAGAATCTTCCGGTCAGCTCTA
TCTGATCCCTTGACCGGACA

Downstream 100 bases:

>100_bases
AGGTGGATGTGTTGTTATTGTGTGTCAATGGCGCTCAATCCCTCCCTTGTCACCCTCTGAAAAAGTTCACACACCCTTCA
CCGTTCAGCCACATTTCCTC

Product: ferrochelatase

Products: NA

Alternate protein names: Heme synthase; Protoheme ferro-lyase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MLSITQSHPLSAFRQSIMHKRIAVILAAHGEAETAGFFDNFSMTRHTLAHAGEVMNLPVPLQLMISVAGGLKNMVKFKKK
NYRSPQNRITRKQAALLAEKLAGQAEAIRYDVHASFFVTPPFVEQIVEQVRDCDMLLLIPMAPIDNRLMSGSLEILAERY
LPPRVPSRPQVISGFWNDPGLLNVYLDHLFMHAAPVPGSALVLAFHGTLEKDQRGNEPEFQTGSKEIATMASALRKAVCN
DPRNGYERVEVAYLNHDVGGTWSSPSLQDMLKSLHRESIASIELFSCGYFSDGTETMLNAREHVVESGIRKAAIIPCLND
SEPFADYLAAKVRDAVTGA

Sequences:

>Translated_339_residues
MLSITQSHPLSAFRQSIMHKRIAVILAAHGEAETAGFFDNFSMTRHTLAHAGEVMNLPVPLQLMISVAGGLKNMVKFKKK
NYRSPQNRITRKQAALLAEKLAGQAEAIRYDVHASFFVTPPFVEQIVEQVRDCDMLLLIPMAPIDNRLMSGSLEILAERY
LPPRVPSRPQVISGFWNDPGLLNVYLDHLFMHAAPVPGSALVLAFHGTLEKDQRGNEPEFQTGSKEIATMASALRKAVCN
DPRNGYERVEVAYLNHDVGGTWSSPSLQDMLKSLHRESIASIELFSCGYFSDGTETMLNAREHVVESGIRKAAIIPCLND
SEPFADYLAAKVRDAVTGA
>Mature_339_residues
MLSITQSHPLSAFRQSIMHKRIAVILAAHGEAETAGFFDNFSMTRHTLAHAGEVMNLPVPLQLMISVAGGLKNMVKFKKK
NYRSPQNRITRKQAALLAEKLAGQAEAIRYDVHASFFVTPPFVEQIVEQVRDCDMLLLIPMAPIDNRLMSGSLEILAERY
LPPRVPSRPQVISGFWNDPGLLNVYLDHLFMHAAPVPGSALVLAFHGTLEKDQRGNEPEFQTGSKEIATMASALRKAVCN
DPRNGYERVEVAYLNHDVGGTWSSPSLQDMLKSLHRESIASIELFSCGYFSDGTETMLNAREHVVESGIRKAAIIPCLND
SEPFADYLAAKVRDAVTGA

Specific function: Catalyzes the ferrous insertion into protoporphyrin IX [H]

COG id: COG0276

COG function: function code H; Protoheme ferro-lyase (ferrochelatase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferrochelatase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001015
- InterPro:   IPR019772 [H]

Pfam domain/function: PF00762 Ferrochelatase [H]

EC number: =4.99.1.1 [H]

Molecular weight: Translated: 37457; Mature: 37457

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSITQSHPLSAFRQSIMHKRIAVILAAHGEAETAGFFDNFSMTRHTLAHAGEVMNLPVP
CCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCHHCHHHHHHHHHHCCCCCCCCCH
LQLMISVAGGLKNMVKFKKKNYRSPQNRITRKQAALLAEKLAGQAEAIRYDVHASFFVTP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEECEEEEECC
PFVEQIVEQVRDCDMLLLIPMAPIDNRLMSGSLEILAERYLPPRVPSRPQVISGFWNDPG
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCC
LLNVYLDHLFMHAAPVPGSALVLAFHGTLEKDQRGNEPEFQTGSKEIATMASALRKAVCN
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHC
DPRNGYERVEVAYLNHDVGGTWSSPSLQDMLKSLHRESIASIELFSCGYFSDGTETMLNA
CCCCCHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHH
REHVVESGIRKAAIIPCLNDSEPFADYLAAKVRDAVTGA
HHHHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSITQSHPLSAFRQSIMHKRIAVILAAHGEAETAGFFDNFSMTRHTLAHAGEVMNLPVP
CCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCHHCHHHHHHHHHHCCCCCCCCCH
LQLMISVAGGLKNMVKFKKKNYRSPQNRITRKQAALLAEKLAGQAEAIRYDVHASFFVTP
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHEEEEECEEEEECC
PFVEQIVEQVRDCDMLLLIPMAPIDNRLMSGSLEILAERYLPPRVPSRPQVISGFWNDPG
HHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCC
LLNVYLDHLFMHAAPVPGSALVLAFHGTLEKDQRGNEPEFQTGSKEIATMASALRKAVCN
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHC
DPRNGYERVEVAYLNHDVGGTWSSPSLQDMLKSLHRESIASIELFSCGYFSDGTETMLNA
CCCCCHHEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHH
REHVVESGIRKAAIIPCLNDSEPFADYLAAKVRDAVTGA
HHHHHHHCCHHEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA