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The map label for this gene is dapD [H]

Identifier: 189499020

GI number: 189499020

Start: 24316

End: 25173

Strand: Direct

Name: dapD [H]

Synonym: Cphamn1_0020

Alternate gene names: 189499020

Gene position: 24316-25173 (Clockwise)

Preceding gene: 189499019

Following gene: 189499021

Centisome position: 0.89

GC content: 52.1

Gene sequence:

>858_bases
ATGCAGCTTGAAGAAGTAAGAACACGTATAGAAGAACTGGCAGCTCTGTCTGCTCCGGAATTACAGAAACACGATGACGC
GCGAGAGGTTTTCAGCGCATTCAAGGTTCTGTTGAACAGCGGCCAGGCAAGAGCGGCGGAGAAAAAAGACAGCTCCTGGC
AGGTAAACGCCTGGGTAAAACAGGGGATTCTCCTGGGGATGAAGCTTGGCATACTCTGCGAGAGTTCGATTGCTTTTCCC
GAAGGCAATGACTGGACATTTGTTGACAAGGATACCTATCCGGTCAGGCGCTTTGTAAAGGAAGATGGTATCCGAATTGT
GCCCGGAGGTTCTTCAGTGAGGGATGGCGCCTATCTGGCTTCTTCAGTGGTTATGATGCCCCCGGCATACGTCAATGTCG
GGGCATATGTCGATGCGGGCAGCATGATTGATTCACACGCTCTTGTAGGCAGCTGCGCACAGGTGGGCCGAAACGTTCAT
CTTTCTGCTGCGGTTCAGGTCGGCGGTGTTCTTGAACCGATAGGCGCTGTTCCGGTAATCATTGAAGATGATGTCATGGT
CGGGGGGAACTGCGGCATTTATGAAGGCACGATCGTCCGTTCGCGATCGGTGATCGGCACAGGCGTCATTCTCAACGGCT
CTACACCTGTCTATGATCTGGTAAACAAAAGCATTATCAGAAAAACCCCTGAAACCCCTCTTACGATTCCTGAAGGAGCA
GTTGTCGTTGCCGGTTCCCGAAAGATACAGGGGGAGTTCGCCGCTGAGCACGGTCTTTCAATCTACACTCCCTTGATCGT
CAAGTACAGGGATGAAAAAACGGATAGTGTGACGGCGCTGGAAAGCGCGTTGCGATGA

Upstream 100 bases:

>100_bases
TGTAATAACATGAATAGTACACAGGGCGGCATGACTTTTCATGGTAAGGCTCAAGACTTGACACTAAAACTATACTATAA
CTCTATTACAATAACCAACA

Downstream 100 bases:

>100_bases
TCACGCTCTCTTTTTCCCGGAACGAGCAAAGAAGACAGGCATGAAACGTTATTCGACAAGCGGTATCGGCAGCATGGTGA
TGCGGGTTTTTGTTTCTCTT

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MQLEEVRTRIEELAALSAPELQKHDDAREVFSAFKVLLNSGQARAAEKKDSSWQVNAWVKQGILLGMKLGILCESSIAFP
EGNDWTFVDKDTYPVRRFVKEDGIRIVPGGSSVRDGAYLASSVVMMPPAYVNVGAYVDAGSMIDSHALVGSCAQVGRNVH
LSAAVQVGGVLEPIGAVPVIIEDDVMVGGNCGIYEGTIVRSRSVIGTGVILNGSTPVYDLVNKSIIRKTPETPLTIPEGA
VVVAGSRKIQGEFAAEHGLSIYTPLIVKYRDEKTDSVTALESALR

Sequences:

>Translated_285_residues
MQLEEVRTRIEELAALSAPELQKHDDAREVFSAFKVLLNSGQARAAEKKDSSWQVNAWVKQGILLGMKLGILCESSIAFP
EGNDWTFVDKDTYPVRRFVKEDGIRIVPGGSSVRDGAYLASSVVMMPPAYVNVGAYVDAGSMIDSHALVGSCAQVGRNVH
LSAAVQVGGVLEPIGAVPVIIEDDVMVGGNCGIYEGTIVRSRSVIGTGVILNGSTPVYDLVNKSIIRKTPETPLTIPEGA
VVVAGSRKIQGEFAAEHGLSIYTPLIVKYRDEKTDSVTALESALR
>Mature_285_residues
MQLEEVRTRIEELAALSAPELQKHDDAREVFSAFKVLLNSGQARAAEKKDSSWQVNAWVKQGILLGMKLGILCESSIAFP
EGNDWTFVDKDTYPVRRFVKEDGIRIVPGGSSVRDGAYLASSVVMMPPAYVNVGAYVDAGSMIDSHALVGSCAQVGRNVH
LSAAVQVGGVLEPIGAVPVIIEDDVMVGGNCGIYEGTIVRSRSVIGTGVILNGSTPVYDLVNKSIIRKTPETPLTIPEGA
VVVAGSRKIQGEFAAEHGLSIYTPLIVKYRDEKTDSVTALESALR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=264, Percent_Identity=40.530303030303, Blast_Score=159, Evalue=2e-40,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 30513; Mature: 30513

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLEEVRTRIEELAALSAPELQKHDDAREVFSAFKVLLNSGQARAAEKKDSSWQVNAWVK
CCHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHH
QGILLGMKLGILCESSIAFPEGNDWTFVDKDTYPVRRFVKEDGIRIVPGGSSVRDGAYLA
CCHHHHEEECEEECCCCCCCCCCCEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCHHHH
SSVVMMPPAYVNVGAYVDAGSMIDSHALVGSCAQVGRNVHLSAAVQVGGVLEPIGAVPVI
HHEEECCCCEEEECCEECCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHCCCCEEEE
IEDDVMVGGNCGIYEGTIVRSRSVIGTGVILNGSTPVYDLVNKSIIRKTPETPLTIPEGA
EECCEEECCCCCCCCCEEEECCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCC
VVVAGSRKIQGEFAAEHGLSIYTPLIVKYRDEKTDSVTALESALR
EEEECCCEECCHHHHHCCCEEECEEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQLEEVRTRIEELAALSAPELQKHDDAREVFSAFKVLLNSGQARAAEKKDSSWQVNAWVK
CCHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHH
QGILLGMKLGILCESSIAFPEGNDWTFVDKDTYPVRRFVKEDGIRIVPGGSSVRDGAYLA
CCHHHHEEECEEECCCCCCCCCCCEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCHHHH
SSVVMMPPAYVNVGAYVDAGSMIDSHALVGSCAQVGRNVHLSAAVQVGGVLEPIGAVPVI
HHEEECCCCEEEECCEECCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHCCCCEEEE
IEDDVMVGGNCGIYEGTIVRSRSVIGTGVILNGSTPVYDLVNKSIIRKTPETPLTIPEGA
EECCEEECCCCCCCCCEEEECCCEEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCC
VVVAGSRKIQGEFAAEHGLSIYTPLIVKYRDEKTDSVTALESALR
EEEECCCEECCHHHHHCCCEEECEEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA