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The map label for this gene is mntH [H]

Identifier: 189352360

GI number: 189352360

Start: 415183

End: 416499

Strand: Direct

Name: mntH [H]

Synonym: BMULJ_03579

Alternate gene names: 189352360

Gene position: 415183-416499 (Clockwise)

Preceding gene: 189352359

Following gene: 189352361

Centisome position: 16.79

GC content: 68.94

Gene sequence:

>1317_bases
ATGCGCTTCCTCCCCACCACCGCTACTGCGCCGTTCTGCCCGTCGGAAGTAAAGGGCAGCATCACGATCGAGGCCGGCGC
GTCGCGCTGGCTGAAGCTCAAGCGTTTCTTCGGACCGGGCCTGCTCGTCGCGATCGGCTACATGGATCCCGGCAACTGGG
CGACCGACATCCAGGCCGGCTCGCAGTTCGGCTATGCGCTGCTGTGGGTCGTCGCGCTGTCGAGCGTCTCCGCGATCTTC
CTGCAGATGCTCGCCGCGCGGCTCGGCCTCGTCGCCGGCCGCGATCTCGCGCAGGCGAGCTACGACCGTTACGGACCGTT
CGGGCGCGTCGTGCAGTGGCTGACGGCCGAGGTCTCGATCATCGCCTGCGACATCGCCGAAGTGCTCGGCTGCGCGCTCG
CGTTCAAGCTGCTGCTCGGCGTGCCGCTCGCGTGGGGCATCGTGCTGACCGCGCTCGACACGGTGATCGTGCTCGGTCTG
CAGGGCAAGGGCGTTCGCCAGATCGAGGCGATCGTGCTCGCGCTGATCGCGACGATGGCGTTCTGCTTCGTCGCGCAGGT
CGCGATCACGCCGCCCGACTGGCGTGCCGTCGCCGCCGGCCTCGTACCGGGCGCGCCGAGCCACGACCGCCACGACGCGA
TCGTGCTCGCGCTCGGCATCGTCGGCGCGACGATCATGCCGCACAACCTCTATCTGCATTCGTCGGTCGTGCAGACGCGG
CGCGTGATCGGCGGCGCGCGCGGCACGATCCGCGACACGCTCGCGCTCGTGCGCATCGACACCTGCGTGTCGCTGTTCGT
CGCGATGCTCGTGAACGCGGCGATCCTGATCGTCGCGGCCGCCGCGTTTCATGCGACGGGCCAGACGCACGTGACCGACA
TCGAGCAGGCGTACAGCCTGATCACGCCGATCGCGGGCGGCGCGGCCGCGCTGCTGTTCGGCATCGCGCTGCTCGCATCG
GGCCAGAGCTCGACGCTGACGGGCACGATCGCCGGCCAGGTGATCATGGACGGCTTCCTGCACATGAAGATTCCGTGCTA
CCAGCGCCGGCTGATCACACGCGGGCTCGCGCTGGTGCCCGCGCTGATCGGCGTATTGTGGCTTGGCGAACATTCGGTCG
GGCAGCTGCTCGTATGGAGCCAGGTGCTGCTGAGCCTGCAGCTGCCGTTCGCGATGTGGCCGCTGATCCGTTCGGTCAGC
GATCGCGCGACAATGGGCGAGCACACGATCGGCCGCGGCATGCAGGCGCTCGCATGGGTGCTGTTCGCGGCGATCACCGG
GACGAACCTGCTGCTGATCGGCGGTGTCGCGGGCTGA

Upstream 100 bases:

>100_bases
GCGTACCGCCGTCGCATCGCATCGTGCGCGACGACGCGCACGAAAAAACGGGCCGGATATCCGTAAAATCGCCGTATCGC
GATTTCGAGCCCCGGTTTCC

Downstream 100 bases:

>100_bases
TACAGCCTGACACACGCTGACACAGACGCCTCGCGCGCATGCGTTAAACTGCGCGCTTTCAGCCGTCGTGCGAATGCAAT
ATGTGGAGTCAAATCAGTAA

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRFLPTTATAPFCPSEVKGSITIEAGASRWLKLKRFFGPGLLVAIGYMDPGNWATDIQAGSQFGYALLWVVALSSVSAIF
LQMLAARLGLVAGRDLAQASYDRYGPFGRVVQWLTAEVSIIACDIAEVLGCALAFKLLLGVPLAWGIVLTALDTVIVLGL
QGKGVRQIEAIVLALIATMAFCFVAQVAITPPDWRAVAAGLVPGAPSHDRHDAIVLALGIVGATIMPHNLYLHSSVVQTR
RVIGGARGTIRDTLALVRIDTCVSLFVAMLVNAAILIVAAAAFHATGQTHVTDIEQAYSLITPIAGGAAALLFGIALLAS
GQSSTLTGTIAGQVIMDGFLHMKIPCYQRRLITRGLALVPALIGVLWLGEHSVGQLLVWSQVLLSLQLPFAMWPLIRSVS
DRATMGEHTIGRGMQALAWVLFAAITGTNLLLIGGVAG

Sequences:

>Translated_438_residues
MRFLPTTATAPFCPSEVKGSITIEAGASRWLKLKRFFGPGLLVAIGYMDPGNWATDIQAGSQFGYALLWVVALSSVSAIF
LQMLAARLGLVAGRDLAQASYDRYGPFGRVVQWLTAEVSIIACDIAEVLGCALAFKLLLGVPLAWGIVLTALDTVIVLGL
QGKGVRQIEAIVLALIATMAFCFVAQVAITPPDWRAVAAGLVPGAPSHDRHDAIVLALGIVGATIMPHNLYLHSSVVQTR
RVIGGARGTIRDTLALVRIDTCVSLFVAMLVNAAILIVAAAAFHATGQTHVTDIEQAYSLITPIAGGAAALLFGIALLAS
GQSSTLTGTIAGQVIMDGFLHMKIPCYQRRLITRGLALVPALIGVLWLGEHSVGQLLVWSQVLLSLQLPFAMWPLIRSVS
DRATMGEHTIGRGMQALAWVLFAAITGTNLLLIGGVAG
>Mature_438_residues
MRFLPTTATAPFCPSEVKGSITIEAGASRWLKLKRFFGPGLLVAIGYMDPGNWATDIQAGSQFGYALLWVVALSSVSAIF
LQMLAARLGLVAGRDLAQASYDRYGPFGRVVQWLTAEVSIIACDIAEVLGCALAFKLLLGVPLAWGIVLTALDTVIVLGL
QGKGVRQIEAIVLALIATMAFCFVAQVAITPPDWRAVAAGLVPGAPSHDRHDAIVLALGIVGATIMPHNLYLHSSVVQTR
RVIGGARGTIRDTLALVRIDTCVSLFVAMLVNAAILIVAAAAFHATGQTHVTDIEQAYSLITPIAGGAAALLFGIALLAS
GQSSTLTGTIAGQVIMDGFLHMKIPCYQRRLITRGLALVPALIGVLWLGEHSVGQLLVWSQVLLSLQLPFAMWPLIRSVS
DRATMGEHTIGRGMQALAWVLFAAITGTNLLLIGGVAG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=429, Percent_Identity=35.1981351981352, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI295293175, Length=438, Percent_Identity=35.8447488584475, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI295293173, Length=438, Percent_Identity=35.8447488584475, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI10835169, Length=438, Percent_Identity=35.8447488584475, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI295293167, Length=438, Percent_Identity=35.8447488584475, Blast_Score=223, Evalue=2e-58,
Organism=Homo sapiens, GI295293178, Length=438, Percent_Identity=35.8447488584475, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI295293171, Length=438, Percent_Identity=35.8447488584475, Blast_Score=223, Evalue=4e-58,
Organism=Homo sapiens, GI295293169, Length=438, Percent_Identity=35.8447488584475, Blast_Score=223, Evalue=4e-58,
Organism=Escherichia coli, GI1788736, Length=417, Percent_Identity=38.1294964028777, Blast_Score=262, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17569473, Length=396, Percent_Identity=34.5959595959596, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71999499, Length=436, Percent_Identity=33.7155963302752, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI193210616, Length=436, Percent_Identity=32.5688073394495, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI71993856, Length=219, Percent_Identity=38.8127853881278, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323062, Length=396, Percent_Identity=38.3838383838384, Blast_Score=240, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6321841, Length=407, Percent_Identity=37.8378378378378, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6324450, Length=420, Percent_Identity=32.8571428571429, Blast_Score=214, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24648607, Length=432, Percent_Identity=33.1018518518519, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI281362176, Length=432, Percent_Identity=33.1018518518519, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24648609, Length=432, Percent_Identity=33.1018518518519, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI45553443, Length=410, Percent_Identity=33.6585365853659, Blast_Score=224, Evalue=8e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 46172; Mature: 46172

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLPTTATAPFCPSEVKGSITIEAGASRWLKLKRFFGPGLLVAIGYMDPGNWATDIQAG
CCCCCCCCCCCCCCHHCCCCEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
SQFGYALLWVVALSSVSAIFLQMLAARLGLVAGRDLAQASYDRYGPFGRVVQWLTAEVSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
IACDIAEVLGCALAFKLLLGVPLAWGIVLTALDTVIVLGLQGKGVRQIEAIVLALIATMA
EEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHH
FCFVAQVAITPPDWRAVAAGLVPGAPSHDRHDAIVLALGIVGATIMPHNLYLHSSVVQTR
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
RVIGGARGTIRDTLALVRIDTCVSLFVAMLVNAAILIVAAAAFHATGQTHVTDIEQAYSL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ITPIAGGAAALLFGIALLASGQSSTLTGTIAGQVIMDGFLHMKIPCYQRRLITRGLALVP
HHCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHH
ALIGVLWLGEHSVGQLLVWSQVLLSLQLPFAMWPLIRSVSDRATMGEHTIGRGMQALAWV
HHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LFAAITGTNLLLIGGVAG
HHHHHCCCCEEEEECCCC
>Mature Secondary Structure
MRFLPTTATAPFCPSEVKGSITIEAGASRWLKLKRFFGPGLLVAIGYMDPGNWATDIQAG
CCCCCCCCCCCCCCHHCCCCEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCC
SQFGYALLWVVALSSVSAIFLQMLAARLGLVAGRDLAQASYDRYGPFGRVVQWLTAEVSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
IACDIAEVLGCALAFKLLLGVPLAWGIVLTALDTVIVLGLQGKGVRQIEAIVLALIATMA
EEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHH
FCFVAQVAITPPDWRAVAAGLVPGAPSHDRHDAIVLALGIVGATIMPHNLYLHSSVVQTR
HHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
RVIGGARGTIRDTLALVRIDTCVSLFVAMLVNAAILIVAAAAFHATGQTHVTDIEQAYSL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ITPIAGGAAALLFGIALLASGQSSTLTGTIAGQVIMDGFLHMKIPCYQRRLITRGLALVP
HHCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHH
ALIGVLWLGEHSVGQLLVWSQVLLSLQLPFAMWPLIRSVSDRATMGEHTIGRGMQALAWV
HHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LFAAITGTNLLLIGGVAG
HHHHHCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]