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The map label for this gene is pkn1 [H]

Identifier: 189352169

GI number: 189352169

Start: 201842

End: 202885

Strand: Direct

Name: pkn1 [H]

Synonym: BMULJ_03387

Alternate gene names: 189352169

Gene position: 201842-202885 (Clockwise)

Preceding gene: 189352168

Following gene: 189352170

Centisome position: 8.16

GC content: 72.22

Gene sequence:

>1044_bases
ATGCGGTTCTGGACGATCGGCGCGGCGCTCGCGGCCGCACTGTTCGGCGCGGCGTTCGCGGCCGGCTATACGCACGGGCC
GGCGGCGCCGGACAGCGCGTTCGACGACGCGAATCGCGACCGACCGCTCGCGGCGCTCGGCTCCGAGCAGCAGTGCGCGC
GCTATTCGGGGTTGCCGGCGAACTGGCGCGACGATCCGAAGGCGGGGATGGTGCACCTGCGCGGCGGCACGTTCGTGTTC
GGCAGCACGCGCGGCTATCAGGACGAACGTCCGGCCGCCGACGGCCGCACGCGCGTCGGCGGTTTCTGGATCGACCAGAC
CGACGTGACGGTCGCGCAGTTCGCCGCTTTCGTGCAGGCGACGGGCTACGTGACCGAGGCCGAGCAGCAGGGCGGCGCGG
CGGTGTTTCACGTGCCGACGCGCGACGAACTGAACGCGCGCGACCTCGCGTGGTGGAGCTGGGTGAAGGGCGCGTCGTGG
CGCCATCCGCGCGGCCCCGGCAGCGACGTCGAGGGGCGCGGCAACCTGCCCGTCACGCTCGTCACGCAGCGCGATGCGCT
CGCGTATGCGCGCTGGCTCGGCCGCGACCTGCCGACCGAAGCCGAATGGGAATACGCGGGCAAGGCCGGCCGCGACGATG
CGTCGCTCGACGCGGCGCCGCGCGATGCGCGCGGCAAGCCGGCCGCCAATTACTGGCAGGGCCCGTTCCCCGTGCTCGAC
ACCGCCGAGGACGGGCACGCGGGGCTCGCGCCGGTCGGCTGCTACGCGGCGAACGGCTTTCGGCTCTACGACATGATCGG
CAACGCCTGGCAGTGGACGAAGGACGTCTACACCGGCCCGCACCAGTCGCATACGAACGGCGACACGGCGGCCGTCGCAC
CGGCCGCACGCCGTCACGACACGCCGATGGTCATCAAGGGCGGCTCGTTCCTATGCTCGCGCGACTACTGCGTGCGCTAT
CGCGCGTCGTCGCGCGAACGGCAGGAAGCCGATCTCGCCGCGTCGCACATCGGATTCCGCACGATCCTGAGGGATCCGGC
ATGA

Upstream 100 bases:

>100_bases
TCGGTGGTCAGCACGCTGATCGATCAGTGGAAGGCGTACATGAGCAACGTCGGCGGCGTCGAGCCGCTGCGTCCGCGCGG
CTACTACTGAGGATTCGGCG

Downstream 100 bases:

>100_bases
TCCGCGTCGCGCGTTTCGTGACGGCCGTCGCGCTCGCGGCGGCCGGTTTCGCCGGCATGCAGGGCGCATGCGCGGCCGAC
GGGCCGGCGCTGCGCGTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MRFWTIGAALAAALFGAAFAAGYTHGPAAPDSAFDDANRDRPLAALGSEQQCARYSGLPANWRDDPKAGMVHLRGGTFVF
GSTRGYQDERPAADGRTRVGGFWIDQTDVTVAQFAAFVQATGYVTEAEQQGGAAVFHVPTRDELNARDLAWWSWVKGASW
RHPRGPGSDVEGRGNLPVTLVTQRDALAYARWLGRDLPTEAEWEYAGKAGRDDASLDAAPRDARGKPAANYWQGPFPVLD
TAEDGHAGLAPVGCYAANGFRLYDMIGNAWQWTKDVYTGPHQSHTNGDTAAVAPAARRHDTPMVIKGGSFLCSRDYCVRY
RASSRERQEADLAASHIGFRTILRDPA

Sequences:

>Translated_347_residues
MRFWTIGAALAAALFGAAFAAGYTHGPAAPDSAFDDANRDRPLAALGSEQQCARYSGLPANWRDDPKAGMVHLRGGTFVF
GSTRGYQDERPAADGRTRVGGFWIDQTDVTVAQFAAFVQATGYVTEAEQQGGAAVFHVPTRDELNARDLAWWSWVKGASW
RHPRGPGSDVEGRGNLPVTLVTQRDALAYARWLGRDLPTEAEWEYAGKAGRDDASLDAAPRDARGKPAANYWQGPFPVLD
TAEDGHAGLAPVGCYAANGFRLYDMIGNAWQWTKDVYTGPHQSHTNGDTAAVAPAARRHDTPMVIKGGSFLCSRDYCVRY
RASSRERQEADLAASHIGFRTILRDPA
>Mature_347_residues
MRFWTIGAALAAALFGAAFAAGYTHGPAAPDSAFDDANRDRPLAALGSEQQCARYSGLPANWRDDPKAGMVHLRGGTFVF
GSTRGYQDERPAADGRTRVGGFWIDQTDVTVAQFAAFVQATGYVTEAEQQGGAAVFHVPTRDELNARDLAWWSWVKGASW
RHPRGPGSDVEGRGNLPVTLVTQRDALAYARWLGRDLPTEAEWEYAGKAGRDDASLDAAPRDARGKPAANYWQGPFPVLD
TAEDGHAGLAPVGCYAANGFRLYDMIGNAWQWTKDVYTGPHQSHTNGDTAAVAPAARRHDTPMVIKGGSFLCSRDYCVRY
RASSRERQEADLAASHIGFRTILRDPA

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI38202250, Length=284, Percent_Identity=38.7323943661972, Blast_Score=194, Evalue=7e-50,
Organism=Homo sapiens, GI257470975, Length=278, Percent_Identity=37.7697841726619, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI257470977, Length=284, Percent_Identity=35.9154929577465, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI194248088, Length=281, Percent_Identity=34.5195729537367, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI194248087, Length=275, Percent_Identity=33.4545454545455, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226437577, Length=220, Percent_Identity=34.5454545454545, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI194248090, Length=196, Percent_Identity=37.7551020408163, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI20130397, Length=330, Percent_Identity=33.6363636363636, Blast_Score=173, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 37647; Mature: 37647

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFWTIGAALAAALFGAAFAAGYTHGPAAPDSAFDDANRDRPLAALGSEQQCARYSGLPA
CCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHCCCCC
NWRDDPKAGMVHLRGGTFVFGSTRGYQDERPAADGRTRVGGFWIDQTDVTVAQFAAFVQA
CCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCEECCEEEECCCCCHHHHHHHHHHH
TGYVTEAEQQGGAAVFHVPTRDELNARDLAWWSWVKGASWRHPRGPGSDVEGRGNLPVTL
CCCEEEHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
VTQRDALAYARWLGRDLPTEAEWEYAGKAGRDDASLDAAPRDARGKPAANYWQGPFPVLD
EECCHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
TAEDGHAGLAPVGCYAANGFRLYDMIGNAWQWTKDVYTGPHQSHTNGDTAAVAPAARRHD
CCCCCCCCCCCCCEEECCCEEEEEHHCCCHHHHHHHHCCCCCCCCCCCCEEECCHHHCCC
TPMVIKGGSFLCSRDYCVRYRASSRERQEADLAASHIGFRTILRDPA
CCEEEECCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRFWTIGAALAAALFGAAFAAGYTHGPAAPDSAFDDANRDRPLAALGSEQQCARYSGLPA
CCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHCCCCC
NWRDDPKAGMVHLRGGTFVFGSTRGYQDERPAADGRTRVGGFWIDQTDVTVAQFAAFVQA
CCCCCCCCCEEEECCCEEEEECCCCCCCCCCCCCCCEECCEEEECCCCCHHHHHHHHHHH
TGYVTEAEQQGGAAVFHVPTRDELNARDLAWWSWVKGASWRHPRGPGSDVEGRGNLPVTL
CCCEEEHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEE
VTQRDALAYARWLGRDLPTEAEWEYAGKAGRDDASLDAAPRDARGKPAANYWQGPFPVLD
EECCHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
TAEDGHAGLAPVGCYAANGFRLYDMIGNAWQWTKDVYTGPHQSHTNGDTAAVAPAARRHD
CCCCCCCCCCCCCEEECCCEEEEEHHCCCHHHHHHHHCCCCCCCCCCCCEEECCHHHCCC
TPMVIKGGSFLCSRDYCVRYRASSRERQEADLAASHIGFRTILRDPA
CCEEEECCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]