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The map label for this gene is ttuB [H]

Identifier: 189352165

GI number: 189352165

Start: 193964

End: 195280

Strand: Direct

Name: ttuB [H]

Synonym: BMULJ_03383

Alternate gene names: 189352165

Gene position: 193964-195280 (Clockwise)

Preceding gene: 189352164

Following gene: 189352168

Centisome position: 7.84

GC content: 68.49

Gene sequence:

>1317_bases
ATGCCGATGACCGCTGCCGCCCCGCCGTTGCATGCCGCGACGATGCGTCGCCTGAACCTGCGGCTGATTCCGTTCCTGAT
GCTGCTCTACCTCGTCGCGTACATCGACCGCTCGAACATCTCGGTCGCCGCGCTGCAGATGAATGCCGATCTCGGCCTGA
GCGCGGAAATGTACGGGCTCGGCGCGGGGCTGTTCTACGTGACGTACATTCTGTTCGAAGTGCCGAGCAACCTGTTTCTC
GCGCGGGTCGGCGCGCGCCGCTGGATCGCGCGCATCATGATCACGTGGGGCGTGATCGCGGCGGGGATGAGCGCCGTGCA
TACGCCCGGACAACTGTATGCGATGCGTCTGCTACTCGGTGCGGCCGAGGCCGGCTTTACGCCGGGCATCATCTACTACC
TCTCCGCGTGGTATCCGGCGAGCGATCGCGCACGCGCGATGTCGTTCTTCTATATCGGGGCGACGCTCGCGTCGGTGATC
GGGCTGCCGCTGTCCGGCGCGCTGCTGAACCTGAACGGCGTGCTCGGCGTCGAGGGCTGGCGCTGGCTGTTCCTGCTCGA
AGGCGTGCCCGCGCTGCTGCTCGGCATCGTCGTGCTGCGTCGTCTGCCCGATACGCCGGCCGATGCGCGCTGGCTGCCGG
CCGACGAGCGCGCGTGGCTCGAAGCGACGCTGCGCGATACCGCGCCGCGCGAGCATCTGTCCCATGGCGCCGCGCTGCGT
CGTGCGTTCGGCGATCGCAACGTGTGGGCGCTCGCGGCGTTCTGGCTGCTGCAGGCGTTCGGCACGATCGGCCTCACGCT
GTTTTTGCCGCTGCTCGTGAAGAGCCTGTCGGGGCAGTCGAGCTTCGCGGTGGGCAGCTTGTCCGCGTTGCCGTTCCTGT
TCGCGTGCGTCGCGATGTATGCGAACGGCCGGCATTCGGATCTCGGCGGCGAGCGTGCGCTGCATCTCGGCGTGCCGATG
CTGCTCGCGGGCGCATTGCTCGTCGGCGCGATCTATGTGCATGTGCTGCCCATCGCGTATGCACTGCTCGTGCTCGCGGT
CGGCTTCAACTGGGCCGCGACGCCGGTGTTCTGGGCCGTGACGACCGAGTACGTGTCGGGGCTGACTGCGGCGGCGTCGA
TCGCGTTGATCAACGCCGTCGCGAATATCGCGGGGCTCGCGCTGCCGCCGGTGATGGGACGCATCAAGGACGTCACGCAT
TCCTACGATCTCGCGCTGCTGCTCGTCGCGGTCGCGCTGCTCGTCGGCGGCGTGCTCGGGCTGCGGATCGCGTCGCGTCG
GCGCGCGATGCCGATGGCCGCGCGGCGGGCGGGATAG

Upstream 100 bases:

>100_bases
TACGGTGTATCGGACAGACAGAAGCGTCGCGCTCACGCGGCGCAACGACGCCGCGCGCCGCGCAACGCGCGCGCGCGGCA
ATCGACTCGATCCAGGAGAC

Downstream 100 bases:

>100_bases
CGCGGTACGCTTCTGTGCCCCGTGCGGCGGCGCCGTGATGAAGCGCGCGCGACGCGTGTGCGATAAGACGCATGCGTCGC
GCGCGGCGCGTTCGTCGACA

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MPMTAAAPPLHAATMRRLNLRLIPFLMLLYLVAYIDRSNISVAALQMNADLGLSAEMYGLGAGLFYVTYILFEVPSNLFL
ARVGARRWIARIMITWGVIAAGMSAVHTPGQLYAMRLLLGAAEAGFTPGIIYYLSAWYPASDRARAMSFFYIGATLASVI
GLPLSGALLNLNGVLGVEGWRWLFLLEGVPALLLGIVVLRRLPDTPADARWLPADERAWLEATLRDTAPREHLSHGAALR
RAFGDRNVWALAAFWLLQAFGTIGLTLFLPLLVKSLSGQSSFAVGSLSALPFLFACVAMYANGRHSDLGGERALHLGVPM
LLAGALLVGAIYVHVLPIAYALLVLAVGFNWAATPVFWAVTTEYVSGLTAAASIALINAVANIAGLALPPVMGRIKDVTH
SYDLALLLVAVALLVGGVLGLRIASRRRAMPMAARRAG

Sequences:

>Translated_438_residues
MPMTAAAPPLHAATMRRLNLRLIPFLMLLYLVAYIDRSNISVAALQMNADLGLSAEMYGLGAGLFYVTYILFEVPSNLFL
ARVGARRWIARIMITWGVIAAGMSAVHTPGQLYAMRLLLGAAEAGFTPGIIYYLSAWYPASDRARAMSFFYIGATLASVI
GLPLSGALLNLNGVLGVEGWRWLFLLEGVPALLLGIVVLRRLPDTPADARWLPADERAWLEATLRDTAPREHLSHGAALR
RAFGDRNVWALAAFWLLQAFGTIGLTLFLPLLVKSLSGQSSFAVGSLSALPFLFACVAMYANGRHSDLGGERALHLGVPM
LLAGALLVGAIYVHVLPIAYALLVLAVGFNWAATPVFWAVTTEYVSGLTAAASIALINAVANIAGLALPPVMGRIKDVTH
SYDLALLLVAVALLVGGVLGLRIASRRRAMPMAARRAG
>Mature_437_residues
PMTAAAPPLHAATMRRLNLRLIPFLMLLYLVAYIDRSNISVAALQMNADLGLSAEMYGLGAGLFYVTYILFEVPSNLFLA
RVGARRWIARIMITWGVIAAGMSAVHTPGQLYAMRLLLGAAEAGFTPGIIYYLSAWYPASDRARAMSFFYIGATLASVIG
LPLSGALLNLNGVLGVEGWRWLFLLEGVPALLLGIVVLRRLPDTPADARWLPADERAWLEATLRDTAPREHLSHGAALRR
AFGDRNVWALAAFWLLQAFGTIGLTLFLPLLVKSLSGQSSFAVGSLSALPFLFACVAMYANGRHSDLGGERALHLGVPML
LAGALLVGAIYVHVLPIAYALLVLAVGFNWAATPVFWAVTTEYVSGLTAAASIALINAVANIAGLALPPVMGRIKDVTHS
YDLALLLVAVALLVGGVLGLRIASRRRAMPMAARRAG

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=468, Percent_Identity=23.2905982905983, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI9966811, Length=460, Percent_Identity=23.0434782608696, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI6912666, Length=277, Percent_Identity=24.5487364620939, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI21322234, Length=418, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082071, Length=410, Percent_Identity=37.8048780487805, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI2367379, Length=423, Percent_Identity=26.4775413711584, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1789152, Length=431, Percent_Identity=23.4338747099768, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789515, Length=430, Percent_Identity=23.953488372093, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082320, Length=433, Percent_Identity=22.8637413394919, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367193, Length=287, Percent_Identity=22.2996515679443, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=366, Percent_Identity=25.9562841530055, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321698, Length=272, Percent_Identity=26.4705882352941, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322612, Length=450, Percent_Identity=22.4444444444444, Blast_Score=83, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=197, Percent_Identity=27.4111675126904, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319250, Length=195, Percent_Identity=25.6410256410256, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6322973, Length=261, Percent_Identity=22.2222222222222, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=219, Percent_Identity=23.7442922374429, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321502, Length=299, Percent_Identity=25.0836120401338, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=160, Percent_Identity=25.625, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550460, Length=465, Percent_Identity=23.6559139784946, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639764, Length=403, Percent_Identity=23.5732009925558, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46884; Mature: 46753

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMTAAAPPLHAATMRRLNLRLIPFLMLLYLVAYIDRSNISVAALQMNADLGLSAEMYGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
GAGLFYVTYILFEVPSNLFLARVGARRWIARIMITWGVIAAGMSAVHTPGQLYAMRLLLG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHH
AAEAGFTPGIIYYLSAWYPASDRARAMSFFYIGATLASVIGLPLSGALLNLNGVLGVEGW
HHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEECCCH
RWLFLLEGVPALLLGIVVLRRLPDTPADARWLPADERAWLEATLRDTAPREHLSHGAALR
HHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
RAFGDRNVWALAAFWLLQAFGTIGLTLFLPLLVKSLSGQSSFAVGSLSALPFLFACVAMY
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ANGRHSDLGGERALHLGVPMLLAGALLVGAIYVHVLPIAYALLVLAVGFNWAATPVFWAV
CCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TTEYVSGLTAAASIALINAVANIAGLALPPVMGRIKDVTHSYDLALLLVAVALLVGGVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRIASRRRAMPMAARRAG
HHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
PMTAAAPPLHAATMRRLNLRLIPFLMLLYLVAYIDRSNISVAALQMNADLGLSAEMYGL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHH
GAGLFYVTYILFEVPSNLFLARVGARRWIARIMITWGVIAAGMSAVHTPGQLYAMRLLLG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHH
AAEAGFTPGIIYYLSAWYPASDRARAMSFFYIGATLASVIGLPLSGALLNLNGVLGVEGW
HHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEECCCH
RWLFLLEGVPALLLGIVVLRRLPDTPADARWLPADERAWLEATLRDTAPREHLSHGAALR
HHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
RAFGDRNVWALAAFWLLQAFGTIGLTLFLPLLVKSLSGQSSFAVGSLSALPFLFACVAMY
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
ANGRHSDLGGERALHLGVPMLLAGALLVGAIYVHVLPIAYALLVLAVGFNWAATPVFWAV
CCCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TTEYVSGLTAAASIALINAVANIAGLALPPVMGRIKDVTHSYDLALLLVAVALLVGGVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRIASRRRAMPMAARRAG
HHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]