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The map label for this gene is lysN [H]

Identifier: 189352151

GI number: 189352151

Start: 180356

End: 181555

Strand: Direct

Name: lysN [H]

Synonym: BMULJ_03369

Alternate gene names: 189352151

Gene position: 180356-181555 (Clockwise)

Preceding gene: 189352150

Following gene: 189352152

Centisome position: 7.29

GC content: 69.92

Gene sequence:

>1200_bases
ATGTACGCGTTCACTCCCTCGTTTCAGCATCCCGCCGGCTCGCCGATTCGCGAGCTGTTCAAGTATCTCGCCGAGCCGGG
GATGATCTCCTTCGCGGGCGGCTATCCGGCCAGCGACCTGTTCGATACGGACGGCCTCGCCGCGGCCGCCGCACGTGCGT
ATGCCCAGCCGGTGCGCTGCCTGCAGTACGGGCCGACCGACGGGCTCGCCGAACTCAAGCAGCAGCTGATCGCACTGATG
GCGCGGCGCGGTGTCGCCTGCACGCCGGCCGAATTGCTCGTCACGACCGGCTCGCAGCAGGGGCTCGACCTGCTGCTGCG
CGTGCTGGTGTCGCCGGGCGACGTCGTGCTGACCGAACAGCCGGCCTATCCGGCGACGCTGCAGGCCATGCGTCTGCAGC
AGGCGCACATCGTCACGATTCCGGTCGACGGTGCAGGCGTCGACGTCGACCGGCTCGCGGCGCGGCTCGCCGACGGCACG
ATCGCGCAGCCGAAGCTGCTCTATACGGTGCCGACCTTCGCGAATCCGACGGGCGCGACGCTCACGCGCGAGCGTCGCCT
GAAGCTGCTGCGCCTCGCCGTGCAGTACCGGTTCCTGATCGTCGAAGACGACCCGTACGGCGACCTGCGTTTTGCCGGCG
AAGCGGTGCCGTCGATGCTCGCGCTCGCCGCCGAAGTCGACGGCGCGCGCGACTGGATCGTGCATTTCGCGAGCCTGTCG
AAGATCGTCGCGCCGGGGCTGCGTGTCGGCTGGACGATTGCGCCGCCCGAAATCGCGCGGCGCTGCGTGATCGCGAAGCA
GACGGTCGACCTCTGCAGCACGCCGTGGACGCAGGCGAGCGCCGCCGAGTATCTCGCGGACGGCGCGCTCGAACGTCATC
TGCCGCGCATCGCCGCCGCATATCGGCGCAAGTGCGACGCGATGTGCGATGCGCTGCGCGACGGTTTCGGCGACGCGATC
GAATTCCACCGGCCCGAAGGCGGGATGTTCGTCTGGGCGCGACTCGGTGCGGTATCGTCGGCGGCGCTGCTGCAGCAGGC
GATCGCGAACAAGGTCGTGTTCGTGCCGGGCAACGCGTTCTTCGCGGACAACCCGGACGACGCATCGCTGCGCCTGTCGT
TCGCCGCGCCGGACGTCGAGGCGATCCGGGAAGGCGTCGCGCGTCTCGCGCGTGCCTATCGCGCGGCGCTGGCCGCTTGA

Upstream 100 bases:

>100_bases
AATCGTGGCTCGAATTCGCCGTCCGCGGCGCGCGACGCGCCGCGCCGGCCGGCCCGCGGCGGCCATCCCGGCCGTTCGCC
GCCATTGAGCCCACGACGAC

Downstream 100 bases:

>100_bases
GGAGAACGGCATGAACATCATCGTCGACGATACCGCCACCGCCAGCGTGCGCCCTGCGTCCGGCGTGCGCCCTGCCGAGC
ATCACTCGTCGCAGATCAGC

Product: 2-aminoadipate transaminase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MYAFTPSFQHPAGSPIRELFKYLAEPGMISFAGGYPASDLFDTDGLAAAAARAYAQPVRCLQYGPTDGLAELKQQLIALM
ARRGVACTPAELLVTTGSQQGLDLLLRVLVSPGDVVLTEQPAYPATLQAMRLQQAHIVTIPVDGAGVDVDRLAARLADGT
IAQPKLLYTVPTFANPTGATLTRERRLKLLRLAVQYRFLIVEDDPYGDLRFAGEAVPSMLALAAEVDGARDWIVHFASLS
KIVAPGLRVGWTIAPPEIARRCVIAKQTVDLCSTPWTQASAAEYLADGALERHLPRIAAAYRRKCDAMCDALRDGFGDAI
EFHRPEGGMFVWARLGAVSSAALLQQAIANKVVFVPGNAFFADNPDDASLRLSFAAPDVEAIREGVARLARAYRAALAA

Sequences:

>Translated_399_residues
MYAFTPSFQHPAGSPIRELFKYLAEPGMISFAGGYPASDLFDTDGLAAAAARAYAQPVRCLQYGPTDGLAELKQQLIALM
ARRGVACTPAELLVTTGSQQGLDLLLRVLVSPGDVVLTEQPAYPATLQAMRLQQAHIVTIPVDGAGVDVDRLAARLADGT
IAQPKLLYTVPTFANPTGATLTRERRLKLLRLAVQYRFLIVEDDPYGDLRFAGEAVPSMLALAAEVDGARDWIVHFASLS
KIVAPGLRVGWTIAPPEIARRCVIAKQTVDLCSTPWTQASAAEYLADGALERHLPRIAAAYRRKCDAMCDALRDGFGDAI
EFHRPEGGMFVWARLGAVSSAALLQQAIANKVVFVPGNAFFADNPDDASLRLSFAAPDVEAIREGVARLARAYRAALAA
>Mature_399_residues
MYAFTPSFQHPAGSPIRELFKYLAEPGMISFAGGYPASDLFDTDGLAAAAARAYAQPVRCLQYGPTDGLAELKQQLIALM
ARRGVACTPAELLVTTGSQQGLDLLLRVLVSPGDVVLTEQPAYPATLQAMRLQQAHIVTIPVDGAGVDVDRLAARLADGT
IAQPKLLYTVPTFANPTGATLTRERRLKLLRLAVQYRFLIVEDDPYGDLRFAGEAVPSMLALAAEVDGARDWIVHFASLS
KIVAPGLRVGWTIAPPEIARRCVIAKQTVDLCSTPWTQASAAEYLADGALERHLPRIAAAYRRKCDAMCDALRDGFGDAI
EFHRPEGGMFVWARLGAVSSAALLQQAIANKVVFVPGNAFFADNPDDASLRLSFAAPDVEAIREGVARLARAYRAALAA

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=414, Percent_Identity=32.3671497584541, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI33469970, Length=414, Percent_Identity=32.3671497584541, Blast_Score=191, Evalue=8e-49,
Organism=Escherichia coli, GI1790797, Length=338, Percent_Identity=30.1775147928994, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787710, Length=340, Percent_Identity=26.4705882352941, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1788722, Length=346, Percent_Identity=27.7456647398844, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=352, Percent_Identity=24.1477272727273, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321236, Length=484, Percent_Identity=25.2066115702479, Blast_Score=116, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6321000, Length=241, Percent_Identity=26.9709543568465, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321929, Length=238, Percent_Identity=24.7899159663866, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356535, Length=397, Percent_Identity=25.4408060453401, Blast_Score=131, Evalue=9e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 42861; Mature: 42861

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAFTPSFQHPAGSPIRELFKYLAEPGMISFAGGYPASDLFDTDGLAAAAARAYAQPVRC
CCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LQYGPTDGLAELKQQLIALMARRGVACTPAELLVTTGSQQGLDLLLRVLVSPGDVVLTEQ
HHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHCCCCEEEECC
PAYPATLQAMRLQQAHIVTIPVDGAGVDVDRLAARLADGTIAQPKLLYTVPTFANPTGAT
CCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCH
LTRERRLKLLRLAVQYRFLIVEDDPYGDLRFAGEAVPSMLALAAEVDGARDWIVHFASLS
HHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KIVAPGLRVGWTIAPPEIARRCVIAKQTVDLCSTPWTQASAAEYLADGALERHLPRIAAA
HHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YRRKCDAMCDALRDGFGDAIEFHRPEGGMFVWARLGAVSSAALLQQAIANKVVFVPGNAF
HHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEECCCEE
FADNPDDASLRLSFAAPDVEAIREGVARLARAYRAALAA
ECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYAFTPSFQHPAGSPIRELFKYLAEPGMISFAGGYPASDLFDTDGLAAAAARAYAQPVRC
CCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LQYGPTDGLAELKQQLIALMARRGVACTPAELLVTTGSQQGLDLLLRVLVSPGDVVLTEQ
HHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHCCCCEEEECC
PAYPATLQAMRLQQAHIVTIPVDGAGVDVDRLAARLADGTIAQPKLLYTVPTFANPTGAT
CCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCH
LTRERRLKLLRLAVQYRFLIVEDDPYGDLRFAGEAVPSMLALAAEVDGARDWIVHFASLS
HHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KIVAPGLRVGWTIAPPEIARRCVIAKQTVDLCSTPWTQASAAEYLADGALERHLPRIAAA
HHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YRRKCDAMCDALRDGFGDAIEFHRPEGGMFVWARLGAVSSAALLQQAIANKVVFVPGNAF
HHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEHHHHHHHHHHHHHHHCCEEEECCCEE
FADNPDDASLRLSFAAPDVEAIREGVARLARAYRAALAA
ECCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA