Click here to switch to the map view.

The map label for this gene is exuT [H]

Identifier: 189352134

GI number: 189352134

Start: 160588

End: 161877

Strand: Direct

Name: exuT [H]

Synonym: BMULJ_03352

Alternate gene names: 189352134

Gene position: 160588-161877 (Clockwise)

Preceding gene: 189352131

Following gene: 189352136

Centisome position: 6.49

GC content: 68.14

Gene sequence:

>1290_bases
ATGCAATCTGCCGTCGTCGGCGTCGTGCGCGCCGCCAGCCGCTACCGCTGGACCGTCTGCGCGCTGCTGTTCTTCGCGAC
CGTCATCAACTACATGGATCGGCAGATCCTCGGCCTGCTCGCACCGATGCTGCAGCACGACATCGGCTGGACGCAGGTGC
AGTACGGCCGCATCGTGATGGCGTTCTCGGCGTTCTATGCGATCGGCCTGCTCGGGTTCGGGCGCATCGTCGACTGGCTC
GGCACGCGCATCTCGTACGCGGTCGCGATGCTGGTCTGGAGCATTGCCGCGATGCTGCACGCGGCGGTCGGCTCGGTGGC
CGGTTTCGCGTTCGTGCGGGCGCTGCTCGGCATCGGCGAGGGCGGCAACTTCCCGGCCGCGATCAAGACGACCGCCGAAT
GGTTTCCGCGCCGCGAACGCGCGCTCGCGACCGGCATCTTCAACTCGGGCGCGAACATCGGTGCGGTGTTCGCGCCGGCG
ATCATTCCGGCGATCGCGGTTGCGTACGGCTGGCGTGCGGCGTTCGTGATCGTCGGCGCGATCGGCATCGTCTGGCTCGC
GGTGTGGCTCGTGTTCTACCGCGCGGCCGATACGCGCGCGCTCGCCGCCGAATACGACGAGCCGCGCGACGAGGCCGAGG
CGCTCGACGCCGCGAACGCCGACGCCGGTGCGCCGCGCTGGCGCGAACTGATCCGCAAGCGCGAGACGTGGGCGTTCCTG
ATCGGCAAGTTCCTGACCGACCCGGTCTGGTGGTTCTATCTGTTCTGGCTGCCGAAGTGGCTGAACGAATCGCGCGGGAT
GGACATGCAGCACATCGGCCTGCCGCTCGTCTGCATCTACGCGCTGACGACGGTCGGCAGCATCGGCGGCGGCTGGATTT
CGTCGATGCTGCTGCGTGCGGGCTGGAGCGTAAACCGCGCGCGCAAGACGGCGATGCTGATCTGCGCATGCTGCGTGCTG
CCGATCGCATTCGTGTCGCAGGTGCAGAACCTGTGGGCGGCGGTGCTGATCGTCGGTCTCGCGGCCGCCGCGCATCAGGG
CTGGTCGGCGAACCTGTTCACGACGGCGTCCGATCTGTTTCCGCGCCGCGCGGTGGCATCGGTGGTCGGGATCGGCGGCA
TGGCCGGCTCGATCGGCGGCGTGCTGTTCTCCGAAGTGATCGGGCAGGTGCTGCAGCGTACGGGCCACTACTGGGTGCTG
TTCGCGATCGGCGCGCTCGCGTATCTGCTCGCGCTCGCGATCATGCATGCGCTGACGCCGAAGATGAAGCCGGCGAAGCT
CGATGCATGA

Upstream 100 bases:

>100_bases
CCGCGCCGTGCAAGCGATGCGCCGCCGCCCGCCCCGGCGCCTGTCGCCGGTCACGAAATACCGTGCGGCGCGACAGGCGC
GGCCGCGCATGGAGACATTC

Downstream 100 bases:

>100_bases
CGGCAGTCGTTCGCGCGTGTGCGCCGCGACGGGCGGCGCACGCGCTGCTTCACGCGGCCGGCGCCGTCGATGCGCGCACG
ATCAGCCGCGGCTCGAACGT

Product: hexuronate transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MQSAVVGVVRAASRYRWTVCALLFFATVINYMDRQILGLLAPMLQHDIGWTQVQYGRIVMAFSAFYAIGLLGFGRIVDWL
GTRISYAVAMLVWSIAAMLHAAVGSVAGFAFVRALLGIGEGGNFPAAIKTTAEWFPRRERALATGIFNSGANIGAVFAPA
IIPAIAVAYGWRAAFVIVGAIGIVWLAVWLVFYRAADTRALAAEYDEPRDEAEALDAANADAGAPRWRELIRKRETWAFL
IGKFLTDPVWWFYLFWLPKWLNESRGMDMQHIGLPLVCIYALTTVGSIGGGWISSMLLRAGWSVNRARKTAMLICACCVL
PIAFVSQVQNLWAAVLIVGLAAAAHQGWSANLFTTASDLFPRRAVASVVGIGGMAGSIGGVLFSEVIGQVLQRTGHYWVL
FAIGALAYLLALAIMHALTPKMKPAKLDA

Sequences:

>Translated_429_residues
MQSAVVGVVRAASRYRWTVCALLFFATVINYMDRQILGLLAPMLQHDIGWTQVQYGRIVMAFSAFYAIGLLGFGRIVDWL
GTRISYAVAMLVWSIAAMLHAAVGSVAGFAFVRALLGIGEGGNFPAAIKTTAEWFPRRERALATGIFNSGANIGAVFAPA
IIPAIAVAYGWRAAFVIVGAIGIVWLAVWLVFYRAADTRALAAEYDEPRDEAEALDAANADAGAPRWRELIRKRETWAFL
IGKFLTDPVWWFYLFWLPKWLNESRGMDMQHIGLPLVCIYALTTVGSIGGGWISSMLLRAGWSVNRARKTAMLICACCVL
PIAFVSQVQNLWAAVLIVGLAAAAHQGWSANLFTTASDLFPRRAVASVVGIGGMAGSIGGVLFSEVIGQVLQRTGHYWVL
FAIGALAYLLALAIMHALTPKMKPAKLDA
>Mature_429_residues
MQSAVVGVVRAASRYRWTVCALLFFATVINYMDRQILGLLAPMLQHDIGWTQVQYGRIVMAFSAFYAIGLLGFGRIVDWL
GTRISYAVAMLVWSIAAMLHAAVGSVAGFAFVRALLGIGEGGNFPAAIKTTAEWFPRRERALATGIFNSGANIGAVFAPA
IIPAIAVAYGWRAAFVIVGAIGIVWLAVWLVFYRAADTRALAAEYDEPRDEAEALDAANADAGAPRWRELIRKRETWAFL
IGKFLTDPVWWFYLFWLPKWLNESRGMDMQHIGLPLVCIYALTTVGSIGGGWISSMLLRAGWSVNRARKTAMLICACCVL
PIAFVSQVQNLWAAVLIVGLAAAAHQGWSANLFTTASDLFPRRAVASVVGIGGMAGSIGGVLFSEVIGQVLQRTGHYWVL
FAIGALAYLLALAIMHALTPKMKPAKLDA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=402, Percent_Identity=23.6318407960199, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI9966811, Length=377, Percent_Identity=24.9336870026525, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI9945322, Length=318, Percent_Identity=27.0440251572327, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI2367193, Length=423, Percent_Identity=30.7328605200946, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87082320, Length=420, Percent_Identity=27.8571428571429, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI2367379, Length=412, Percent_Identity=28.3980582524272, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789152, Length=433, Percent_Identity=27.4826789838337, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789515, Length=413, Percent_Identity=25.90799031477, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI87082071, Length=384, Percent_Identity=23.9583333333333, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17535049, Length=419, Percent_Identity=25.5369928400955, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=405, Percent_Identity=23.4567901234568, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI115533554, Length=403, Percent_Identity=23.3250620347395, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17569727, Length=389, Percent_Identity=23.1362467866324, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=209, Percent_Identity=22.9665071770335, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648416, Length=389, Percent_Identity=26.2210796915167, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356189, Length=389, Percent_Identity=26.2210796915167, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920686, Length=404, Percent_Identity=22.5247524752475, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24580790, Length=317, Percent_Identity=19.8738170347003, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20130167, Length=429, Percent_Identity=25.1748251748252, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24583789, Length=274, Percent_Identity=22.6277372262774, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639764, Length=361, Percent_Identity=22.1606648199446, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584153, Length=272, Percent_Identity=23.1617647058824, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28573299, Length=382, Percent_Identity=24.3455497382199, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24655271, Length=421, Percent_Identity=21.6152019002375, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130135, Length=421, Percent_Identity=21.6152019002375, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641682, Length=387, Percent_Identity=24.2894056847545, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658658, Length=439, Percent_Identity=22.5512528473804, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46547; Mature: 46547

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAVVGVVRAASRYRWTVCALLFFATVINYMDRQILGLLAPMLQHDIGWTQVQYGRIVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AFSAFYAIGLLGFGRIVDWLGTRISYAVAMLVWSIAAMLHAAVGSVAGFAFVRALLGIGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGNFPAAIKTTAEWFPRRERALATGIFNSGANIGAVFAPAIIPAIAVAYGWRAAFVIVGA
CCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIVWLAVWLVFYRAADTRALAAEYDEPRDEAEALDAANADAGAPRWRELIRKRETWAFL
HHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
IGKFLTDPVWWFYLFWLPKWLNESRGMDMQHIGLPLVCIYALTTVGSIGGGWISSMLLRA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHH
GWSVNRARKTAMLICACCVLPIAFVSQVQNLWAAVLIVGLAAAAHQGWSANLFTTASDLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
PRRAVASVVGIGGMAGSIGGVLFSEVIGQVLQRTGHYWVLFAIGALAYLLALAIMHALTP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
KMKPAKLDA
CCCCCCCCC
>Mature Secondary Structure
MQSAVVGVVRAASRYRWTVCALLFFATVINYMDRQILGLLAPMLQHDIGWTQVQYGRIVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
AFSAFYAIGLLGFGRIVDWLGTRISYAVAMLVWSIAAMLHAAVGSVAGFAFVRALLGIGE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GGNFPAAIKTTAEWFPRRERALATGIFNSGANIGAVFAPAIIPAIAVAYGWRAAFVIVGA
CCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIVWLAVWLVFYRAADTRALAAEYDEPRDEAEALDAANADAGAPRWRELIRKRETWAFL
HHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
IGKFLTDPVWWFYLFWLPKWLNESRGMDMQHIGLPLVCIYALTTVGSIGGGWISSMLLRA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHH
GWSVNRARKTAMLICACCVLPIAFVSQVQNLWAAVLIVGLAAAAHQGWSANLFTTASDLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
PRRAVASVVGIGGMAGSIGGVLFSEVIGQVLQRTGHYWVLFAIGALAYLLALAIMHALTP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
KMKPAKLDA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]