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The map label for this gene is sohB [H]

Identifier: 189184683

GI number: 189184683

Start: 1801406

End: 1802323

Strand: Reverse

Name: sohB [H]

Synonym: OTT_1776

Alternate gene names: 189184683

Gene position: 1802323-1801406 (Counterclockwise)

Preceding gene: 189184687

Following gene: 189184678

Centisome position: 89.71

GC content: 31.26

Gene sequence:

>918_bases
ATGGAAATTATTAGTAAAAATCATACTAATTCTTTAGATAAGGCAATATTGCGACAACCAGCTAGTAAAATTGACAAATT
ATTATCTTGCTTACATTGCGGTTTGTTGAATAACAAGAGTGTGGTATCAGTTATTCACTTAACTGGTATTATTGGTAAGG
TTGGTAGTTTTAAGTCTGGGCTTACTTTACATACATTAAATTCTGTAATAGAAAAAGCTTTTTCATTTAAGAAATTAACC
GCTGTATGCTTGGTAGTAAATTCTCCTGGTGGTTCTCCTGTACAATCAGAATTAATAGCAAGCAGAATTCTTCAGCTATC
AAATCAAAAAAATGTGCCTGTATATAGCTTTGTTGAAGATGTCGCAGCATCAGGAGGATATTGGTTAGCTTGTGCTGGCA
AAAAGATTTACGCTTCTAAAAGTTCGATCATTGGCAGCATAGGTGTTATTTATATGGGATTTGGTCTGCATGAAGCAATA
GGCAAGCTTGGCATTAAGCGAAGAGTTTATACTTCTGGAAATAATAAATCTATATTAGATCCATTCATGCCAGAAAAAGA
TAGTGATATAAAAATCATTCAAAACTTGCAGAAAAAGATACATAATCATTTTATCAGTTATATTAAATCAAGGCGAGGAG
ATAAAATTACTCAAGAAGATAAAGTTATTTATAATGGTGAGTTTTGGTCTGGAGAGCAAGCTTTAGAATATGGATTAATA
GATGGCATAAACGATATGTATAGCTTTCTAAATACCAAATATGGTGATTCTATTAAAATAGAGTATGTATCTACTAAGCA
AAGTTGGATCAAACGCAAGTTAGGTTTGATAATAGATATTGGAGCTGATAGTCTTGTTCAAAAAACATTAAAAGCTATTG
AACATAATGCATCTACTAATAAGTATAACTTACATTAA

Upstream 100 bases:

>100_bases
ACTTTTTTAATATAGCACAGGGTTTATAATCAATAAAAAATTTGAAATTATAAATTCTATGTGTTTATATAGCAACCATA
TAAATTAGAGGATACTCAGC

Downstream 100 bases:

>100_bases
TAAGTAGTTAGAAATAATTGAGAAGAATAAAAAAAGTTCTTTTTATTCTTCTGTTAGAACCACATTGTGCTAAATTTAAG
AATGATCTCAAGACATAACC

Product: SohB protease

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MEIISKNHTNSLDKAILRQPASKIDKLLSCLHCGLLNNKSVVSVIHLTGIIGKVGSFKSGLTLHTLNSVIEKAFSFKKLT
AVCLVVNSPGGSPVQSELIASRILQLSNQKNVPVYSFVEDVAASGGYWLACAGKKIYASKSSIIGSIGVIYMGFGLHEAI
GKLGIKRRVYTSGNNKSILDPFMPEKDSDIKIIQNLQKKIHNHFISYIKSRRGDKITQEDKVIYNGEFWSGEQALEYGLI
DGINDMYSFLNTKYGDSIKIEYVSTKQSWIKRKLGLIIDIGADSLVQKTLKAIEHNASTNKYNLH

Sequences:

>Translated_305_residues
MEIISKNHTNSLDKAILRQPASKIDKLLSCLHCGLLNNKSVVSVIHLTGIIGKVGSFKSGLTLHTLNSVIEKAFSFKKLT
AVCLVVNSPGGSPVQSELIASRILQLSNQKNVPVYSFVEDVAASGGYWLACAGKKIYASKSSIIGSIGVIYMGFGLHEAI
GKLGIKRRVYTSGNNKSILDPFMPEKDSDIKIIQNLQKKIHNHFISYIKSRRGDKITQEDKVIYNGEFWSGEQALEYGLI
DGINDMYSFLNTKYGDSIKIEYVSTKQSWIKRKLGLIIDIGADSLVQKTLKAIEHNASTNKYNLH
>Mature_305_residues
MEIISKNHTNSLDKAILRQPASKIDKLLSCLHCGLLNNKSVVSVIHLTGIIGKVGSFKSGLTLHTLNSVIEKAFSFKKLT
AVCLVVNSPGGSPVQSELIASRILQLSNQKNVPVYSFVEDVAASGGYWLACAGKKIYASKSSIIGSIGVIYMGFGLHEAI
GKLGIKRRVYTSGNNKSILDPFMPEKDSDIKIIQNLQKKIHNHFISYIKSRRGDKITQEDKVIYNGEFWSGEQALEYGLI
DGINDMYSFLNTKYGDSIKIEYVSTKQSWIKRKLGLIIDIGADSLVQKTLKAIEHNASTNKYNLH

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=195, Percent_Identity=31.2820512820513, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788064, Length=180, Percent_Identity=31.1111111111111, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 33694; Mature: 33694

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00264 NEUROHYPOPHYS_HORM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIISKNHTNSLDKAILRQPASKIDKLLSCLHCGLLNNKSVVSVIHLTGIIGKVGSFKSG
CCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
LTLHTLNSVIEKAFSFKKLTAVCLVVNSPGGSPVQSELIASRILQLSNQKNVPVYSFVED
CHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VAASGGYWLACAGKKIYASKSSIIGSIGVIYMGFGLHEAIGKLGIKRRVYTSGNNKSILD
HHCCCCEEEEECCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCCCCCCC
PFMPEKDSDIKIIQNLQKKIHNHFISYIKSRRGDKITQEDKVIYNGEFWSGEQALEYGLI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHH
DGINDMYSFLNTKYGDSIKIEYVSTKQSWIKRKLGLIIDIGADSLVQKTLKAIEHNASTN
CCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCC
KYNLH
CCCCC
>Mature Secondary Structure
MEIISKNHTNSLDKAILRQPASKIDKLLSCLHCGLLNNKSVVSVIHLTGIIGKVGSFKSG
CCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
LTLHTLNSVIEKAFSFKKLTAVCLVVNSPGGSPVQSELIASRILQLSNQKNVPVYSFVED
CHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VAASGGYWLACAGKKIYASKSSIIGSIGVIYMGFGLHEAIGKLGIKRRVYTSGNNKSILD
HHCCCCEEEEECCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCCCCCCC
PFMPEKDSDIKIIQNLQKKIHNHFISYIKSRRGDKITQEDKVIYNGEFWSGEQALEYGLI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHH
DGINDMYSFLNTKYGDSIKIEYVSTKQSWIKRKLGLIIDIGADSLVQKTLKAIEHNASTN
CCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCC
KYNLH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA