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The map label for this gene is rodA [H]

Identifier: 189184487

GI number: 189184487

Start: 1610741

End: 1611874

Strand: Reverse

Name: rodA [H]

Synonym: OTT_1580

Alternate gene names: 189184487

Gene position: 1611874-1610741 (Counterclockwise)

Preceding gene: 189184488

Following gene: 189184486

Centisome position: 80.23

GC content: 30.78

Gene sequence:

>1134_bases
ATGCAGATATACCAGAATAGATCATTAGTTAAGGATAAACTTAAAATGTTGCCATTTACATTAATATTAACAATATGCAT
AGTTTGTATTTTTGGATTGATAACATTATACTCTGCAACTGGTTGTAAGTTTTTTTTGCGCGCTCATAAGCAAATTCTAT
ATTATATTACGTTTTTACCAATTGGAATACTGTTAGCCTTAGTAGATGTAAGATATATATATAAATACTCGTATATTTTA
TATTTTATTGTGTGTGTTGTATTAGTTATGGTTGAGATTGCAGGATATAAGGTAATGGGGGCAAGGAGATGGATAGGTAT
TTCTGCTCTCAGAATTCAACCTTCTGAAGTTGCAAAAATTTCTGTCATTTTAATGCTAGCTAGATATTTTCATGACATTA
GTGTTTATAAACTAAAAAAGATACAGTATAGTATAGTTCCGCTATTATTAATAGCGATACCAATAACGTTAGTAATTAAA
CAACCAGATTTAGGCACTGGAATAATTATACTGCTTATTACAGCATCAATGTTTTTTGCAGCAGGAATAACACTATGGAT
ATTTATTATTACATTTATAGCTGGAATAATTCTCTTGCCTATTATTTGGAACCTTTTACATAATTACCAAAAGAAACGCA
TTAAAGTTTTTCTTAATCCAGAACTTGATCCACTAGGTTCTGGGTACAATATTATTCAGTCTAAAGTTGCGATAGGTTCC
GGGGGGTTAAGCGGTAAAGGTTTTGCCCAAGGAACTCAAAGCCATTTAAATTTTCTGCCAGAACCTCAAACTGATTTTAT
TTTTGCTTGTCTAGGAGAAGAATTTGGGTTTATTGGTGGGTTTCTGCTATTAACTTTATATTTTATAATAATTTGCTATT
CTTTAGTAATTGCAATTAATGTAAGAAATACTTTTTGCAAATTAGTTGCAATTGGCATTGTTTCTATGCTTTTCTGGCAT
GTTTTTATTAATATTGCTATGGTAACAGGTCTACTACCTGTTGTTGGAATTCCCTTGCCGTTAATATCTTATGGAGGAAC
GATAATTGCTTCTACGCTTCTTGGGATTGGACTAGTTATGAATAGTTATGTCAATAAAGACGTTGATATAGTTAAATCGC
ATTATTTATCATAA

Upstream 100 bases:

>100_bases
GATCTAAAATAAAATCTAGCATTGAAACTAAGAATAGTAATGAGAAAAATTTATTATTAAGGTATGCTTAAACTAATAAT
CCATAAGTGAAATATTCAAA

Downstream 100 bases:

>100_bases
AAATTATGCTTTATCAGTCGGTAATTTTTTATTTTATAATTCTACTTTCTGGTGTACTTAATTTTATTTTATTTAATTTA
AGAATCGATAGTACTGCTTT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MQIYQNRSLVKDKLKMLPFTLILTICIVCIFGLITLYSATGCKFFLRAHKQILYYITFLPIGILLALVDVRYIYKYSYIL
YFIVCVVLVMVEIAGYKVMGARRWIGISALRIQPSEVAKISVILMLARYFHDISVYKLKKIQYSIVPLLLIAIPITLVIK
QPDLGTGIIILLITASMFFAAGITLWIFIITFIAGIILLPIIWNLLHNYQKKRIKVFLNPELDPLGSGYNIIQSKVAIGS
GGLSGKGFAQGTQSHLNFLPEPQTDFIFACLGEEFGFIGGFLLLTLYFIIICYSLVIAINVRNTFCKLVAIGIVSMLFWH
VFINIAMVTGLLPVVGIPLPLISYGGTIIASTLLGIGLVMNSYVNKDVDIVKSHYLS

Sequences:

>Translated_377_residues
MQIYQNRSLVKDKLKMLPFTLILTICIVCIFGLITLYSATGCKFFLRAHKQILYYITFLPIGILLALVDVRYIYKYSYIL
YFIVCVVLVMVEIAGYKVMGARRWIGISALRIQPSEVAKISVILMLARYFHDISVYKLKKIQYSIVPLLLIAIPITLVIK
QPDLGTGIIILLITASMFFAAGITLWIFIITFIAGIILLPIIWNLLHNYQKKRIKVFLNPELDPLGSGYNIIQSKVAIGS
GGLSGKGFAQGTQSHLNFLPEPQTDFIFACLGEEFGFIGGFLLLTLYFIIICYSLVIAINVRNTFCKLVAIGIVSMLFWH
VFINIAMVTGLLPVVGIPLPLISYGGTIIASTLLGIGLVMNSYVNKDVDIVKSHYLS
>Mature_377_residues
MQIYQNRSLVKDKLKMLPFTLILTICIVCIFGLITLYSATGCKFFLRAHKQILYYITFLPIGILLALVDVRYIYKYSYIL
YFIVCVVLVMVEIAGYKVMGARRWIGISALRIQPSEVAKISVILMLARYFHDISVYKLKKIQYSIVPLLLIAIPITLVIK
QPDLGTGIIILLITASMFFAAGITLWIFIITFIAGIILLPIIWNLLHNYQKKRIKVFLNPELDPLGSGYNIIQSKVAIGS
GGLSGKGFAQGTQSHLNFLPEPQTDFIFACLGEEFGFIGGFLLLTLYFIIICYSLVIAINVRNTFCKLVAIGIVSMLFWH
VFINIAMVTGLLPVVGIPLPLISYGGTIIASTLLGIGLVMNSYVNKDVDIVKSHYLS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=365, Percent_Identity=40.2739726027397, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1786277, Length=353, Percent_Identity=32.5779036827195, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42112; Mature: 42112

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIYQNRSLVKDKLKMLPFTLILTICIVCIFGLITLYSATGCKFFLRAHKQILYYITFLP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IGILLALVDVRYIYKYSYILYFIVCVVLVMVEIAGYKVMGARRWIGISALRIQPSEVAKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHCCEEEEEECHHHHHHH
SVILMLARYFHDISVYKLKKIQYSIVPLLLIAIPITLVIKQPDLGTGIIILLITASMFFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHH
AGITLWIFIITFIAGIILLPIIWNLLHNYQKKRIKVFLNPELDPLGSGYNIIQSKVAIGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHCCC
GGLSGKGFAQGTQSHLNFLPEPQTDFIFACLGEEFGFIGGFLLLTLYFIIICYSLVIAIN
CCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRNTFCKLVAIGIVSMLFWHVFINIAMVTGLLPVVGIPLPLISYGGTIIASTLLGIGLVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHH
NSYVNKDVDIVKSHYLS
HHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MQIYQNRSLVKDKLKMLPFTLILTICIVCIFGLITLYSATGCKFFLRAHKQILYYITFLP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IGILLALVDVRYIYKYSYILYFIVCVVLVMVEIAGYKVMGARRWIGISALRIQPSEVAKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHCCEEEEEECHHHHHHH
SVILMLARYFHDISVYKLKKIQYSIVPLLLIAIPITLVIKQPDLGTGIIILLITASMFFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHH
AGITLWIFIITFIAGIILLPIIWNLLHNYQKKRIKVFLNPELDPLGSGYNIIQSKVAIGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHCCC
GGLSGKGFAQGTQSHLNFLPEPQTDFIFACLGEEFGFIGGFLLLTLYFIIICYSLVIAIN
CCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRNTFCKLVAIGIVSMLFWHVFINIAMVTGLLPVVGIPLPLISYGGTIIASTLLGIGLVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHH
NSYVNKDVDIVKSHYLS
HHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]