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The map label for this gene is clpP [H]

Identifier: 189026264

GI number: 189026264

Start: 1138665

End: 1139378

Strand: Reverse

Name: clpP [H]

Synonym: TPASS_1041

Alternate gene names: 189026264

Gene position: 1139378-1138665 (Counterclockwise)

Preceding gene: NA

Following gene: 189026263

Centisome position: 99.99

GC content: 47.48

Gene sequence:

>714_bases
TTGTTATTCAAGAGAAGTTTTTATGCTACACTAAGCGGCTCTTGTTTAGTGTGGGGCTGTTGCGCGACAGTATACCGTGA
GCATGCCCGCGAGAAATGGGGAGTCGGAGTGGTTATGAGGTGTGATGCTACGCAGGAAAAACGTGCGCACTCAGAATCAG
GGGAGAGTGTTTTTTTCCAGAAGTTTTTGGAAACGCGGCAAATTCTCCTTTCAGGGGAAATAAGTAAAGACCTCGCAGAG
GGAATAGTACGGCAACTCTTTGTATTGGAGTCTCTTTCCGTTTCGAAGCCCATCTATATGTACGTGGATTCTCCTGGGGG
GGATGTGGATGCAGGGTACGCTATTTTTGACGTTATTCGCTTCGTCAAGACGCCAGTGTACACAATTGGAATGGGGTTGG
TTGCGAGTGCTGGTGTACTCGTTTTGCTCGCGGCAAAAAAGGATTGTAGGTTTGGATTGCGCAATAGCCGGTACTTGATA
CACCAACCCCTTTCTGGTATGCGTGGCGTTGCGACAGACATAGAAATCCACGCACGGGAGCTTGAGAAAACGCGATCGAA
ACTGAACGCTTTGATCGCAAGTGAAACGGGTGTGAGCTTAGATAAAGTTGCACAGGATACAAATCGAGACTACTGGCTCG
ACGCTTCTCAAGCACTAGAATATGGTCTCATTTCGAACCTGATTGAAAAAAGGGCGGACCTTCCTAAGAAATAA

Upstream 100 bases:

>100_bases
ATACCCTACTGCGTCCATCTACCTATGATACAACCTATTGTATTTTGCCTGCAATAAACGAAGAGGTTATACGCGCGTTG
CTTTGTGGGTGTAGATTATC

Downstream 100 bases:

>100_bases
TGGATACCGAATCTGTCCTCTTTCGCGCGCAGTGCTTGCGTGCAGTGCGTGATTTTTTCCTTGAACACCACTACATAGAG
CTCGATACGCCTGCACTCGC

Product: ATP-dependent Clp protease proteolytic subunit

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MLFKRSFYATLSGSCLVWGCCATVYREHAREKWGVGVVMRCDATQEKRAHSESGESVFFQKFLETRQILLSGEISKDLAE
GIVRQLFVLESLSVSKPIYMYVDSPGGDVDAGYAIFDVIRFVKTPVYTIGMGLVASAGVLVLLAAKKDCRFGLRNSRYLI
HQPLSGMRGVATDIEIHARELEKTRSKLNALIASETGVSLDKVAQDTNRDYWLDASQALEYGLISNLIEKRADLPKK

Sequences:

>Translated_237_residues
MLFKRSFYATLSGSCLVWGCCATVYREHAREKWGVGVVMRCDATQEKRAHSESGESVFFQKFLETRQILLSGEISKDLAE
GIVRQLFVLESLSVSKPIYMYVDSPGGDVDAGYAIFDVIRFVKTPVYTIGMGLVASAGVLVLLAAKKDCRFGLRNSRYLI
HQPLSGMRGVATDIEIHARELEKTRSKLNALIASETGVSLDKVAQDTNRDYWLDASQALEYGLISNLIEKRADLPKK
>Mature_237_residues
MLFKRSFYATLSGSCLVWGCCATVYREHAREKWGVGVVMRCDATQEKRAHSESGESVFFQKFLETRQILLSGEISKDLAE
GIVRQLFVLESLSVSKPIYMYVDSPGGDVDAGYAIFDVIRFVKTPVYTIGMGLVASAGVLVLLAAKKDCRFGLRNSRYLI
HQPLSGMRGVATDIEIHARELEKTRSKLNALIASETGVSLDKVAQDTNRDYWLDASQALEYGLISNLIEKRADLPKK

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=171, Percent_Identity=37.4269005847953, Blast_Score=125, Evalue=3e-29,
Organism=Escherichia coli, GI1786641, Length=180, Percent_Identity=45.5555555555556, Blast_Score=166, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17538017, Length=178, Percent_Identity=35.9550561797753, Blast_Score=134, Evalue=4e-32,
Organism=Drosophila melanogaster, GI20129427, Length=176, Percent_Identity=36.3636363636364, Blast_Score=131, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 26381; Mature: 26381

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKRSFYATLSGSCLVWGCCATVYREHAREKWGVGVVMRCDATQEKRAHSESGESVFFQ
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCHHHHH
KFLETRQILLSGEISKDLAEGIVRQLFVLESLSVSKPIYMYVDSPGGDVDAGYAIFDVIR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
FVKTPVYTIGMGLVASAGVLVLLAAKKDCRFGLRNSRYLIHQPLSGMRGVATDIEIHARE
HHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
LEKTRSKLNALIASETGVSLDKVAQDTNRDYWLDASQALEYGLISNLIEKRADLPKK
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLFKRSFYATLSGSCLVWGCCATVYREHAREKWGVGVVMRCDATQEKRAHSESGESVFFQ
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHCCCCCHHHHH
KFLETRQILLSGEISKDLAEGIVRQLFVLESLSVSKPIYMYVDSPGGDVDAGYAIFDVIR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHH
FVKTPVYTIGMGLVASAGVLVLLAAKKDCRFGLRNSRYLIHQPLSGMRGVATDIEIHARE
HHHCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
LEKTRSKLNALIASETGVSLDKVAQDTNRDYWLDASQALEYGLISNLIEKRADLPKK
HHHHHHHHHHHHHCCCCCCHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]