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The map label for this gene is sms

Identifier: 189026245

GI number: 189026245

Start: 1116489

End: 1117856

Strand: Reverse

Name: sms

Synonym: TPASS_1022

Alternate gene names: 189026245

Gene position: 1117856-1116489 (Counterclockwise)

Preceding gene: 189026246

Following gene: 189026240

Centisome position: 98.1

GC content: 49.78

Gene sequence:

>1368_bases
GTGGCTAAAAAGACGGAACGTGCCTTTTCCTGCGTGGGGTGTGGTTACGTTCATCCTAAGTGGCTTGGGCGTTGCCCTGA
GTGCGGGGAGTGGAATTCCTTCGAAGAGACACCCTCGTTGTCCTCCGGCGATGTTCGTGCTGTAAAAAAGGCATCTTCTT
CTCCTGTACAGGCGTTCCCGCTGTGTGCTGTGCGCGCGCAGGATGCGCAGCGTATTAGTTGTGGTATCGCAGAGTTCGAT
CGTGTCCTCGGCGGAGGCGCCGTAAGACGCTCCGCGATCATGATTGGCGGGGAACCGGGCATTGGTAAATCTACATTACT
GTTACAAATCGCTGCAGCCTGCGGGAAATCGGTTCTCTATGTTTCGGGTGAAGAATCTCCGGGGCAAATTCGTGGGCGTG
CGGATCGGCTGAATATTCCAATTCAGAACATCGAGTTGCTTTGTGCGACGCGGGTCGAGGATGTCGAGCGTGTTTTAAAT
ACACGATGCCCTACCTTCGTTATTGTTGATTCGATTCAGACAGTTTTTTCCCCCGAAGCAGGTGCCATTCCTATGACTAT
CAATCAGCTGAAATATTGCGCAAATGAGTTGATAGCGTGGGTAAAGGAACGGGACTCTGTTCTCTTTTTTACTGCGCATG
TAACGAAAGATGGGAATATTGCCGGGCCAAAAGTAGTGGAACATATGGTGGACACTGTGATTTCTTTTGAACGGAATGAA
GAGGATATTCGTTTTTTACGTGCATTGAAAAATCGATTTGGTTCTGTTGATGAGCTGGGTATTTTTACCATGGGTGAAAA
TGGACTTTCCGCTGTGCAGGACACTGCAGGATTTTTTATTAGTACCAGGCAGGGAATGTTTCCTGTTGGGTCTGCAACTG
TGCCCGTGTGTGAGGGGAGCCGTGTTTTTATGGTAGAAATACAGGCATTGACCGTTCCTGCAAAAAGTAGTGTTACGCGC
GTTTTTTCTGATCGTATCGACTCGGCCCGCGTCAGTCGTGTTGCAGCGGTAATTGAGAAACGTGTGGGTTTGAAATTCTC
AGATCAGGATATCTACGTGAATGTGGCAGGGGGTATCCGGTTATATGAGCCTGCGGTGGATGTGGCGTTGGCAATGGCCT
TGTATTCAGCGCGGCAAAACACCCCAGTGAAAACAAATGCCGCGTTTATCGGTGAGGTAAGTTTATCAGGAGAAATTCGA
CCTGTGCGTCGGCTAAAGACGCGGCTAAAGACGGCGTATGGTCTGGGATTTTCAACGATATATGTACCTATAGGGGTTGA
ACACGACACACCGCCTCCTTATACCCTACGGGTGGTGGGTACGCTCGCACAGACAATTGCGGAGATATTTAGCAAGGCGA
AGGCGTAG

Upstream 100 bases:

>100_bases
TTTTCTCCTTCGCTCGTTCGTCGCTGTCTTGCGGTAGAAACGGAGGGTGCGTAGCGGCCCGCCGTGCAGTGCTTTTTCTT
TCTGACGTAAGAGAAATGGA

Downstream 100 bases:

>100_bases
TAGCCCTTTGGTGCGTCTTTCTTCTCCTGGCGTGAGCCGGGCCGGGCGTATGCTGAAAGAGAGACCGCCGCTCTTCCGTG
GAGTTTTTCCAGCTGTTACA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MAKKTERAFSCVGCGYVHPKWLGRCPECGEWNSFEETPSLSSGDVRAVKKASSSPVQAFPLCAVRAQDAQRISCGIAEFD
RVLGGGAVRRSAIMIGGEPGIGKSTLLLQIAAACGKSVLYVSGEESPGQIRGRADRLNIPIQNIELLCATRVEDVERVLN
TRCPTFVIVDSIQTVFSPEAGAIPMTINQLKYCANELIAWVKERDSVLFFTAHVTKDGNIAGPKVVEHMVDTVISFERNE
EDIRFLRALKNRFGSVDELGIFTMGENGLSAVQDTAGFFISTRQGMFPVGSATVPVCEGSRVFMVEIQALTVPAKSSVTR
VFSDRIDSARVSRVAAVIEKRVGLKFSDQDIYVNVAGGIRLYEPAVDVALAMALYSARQNTPVKTNAAFIGEVSLSGEIR
PVRRLKTRLKTAYGLGFSTIYVPIGVEHDTPPPYTLRVVGTLAQTIAEIFSKAKA

Sequences:

>Translated_455_residues
MAKKTERAFSCVGCGYVHPKWLGRCPECGEWNSFEETPSLSSGDVRAVKKASSSPVQAFPLCAVRAQDAQRISCGIAEFD
RVLGGGAVRRSAIMIGGEPGIGKSTLLLQIAAACGKSVLYVSGEESPGQIRGRADRLNIPIQNIELLCATRVEDVERVLN
TRCPTFVIVDSIQTVFSPEAGAIPMTINQLKYCANELIAWVKERDSVLFFTAHVTKDGNIAGPKVVEHMVDTVISFERNE
EDIRFLRALKNRFGSVDELGIFTMGENGLSAVQDTAGFFISTRQGMFPVGSATVPVCEGSRVFMVEIQALTVPAKSSVTR
VFSDRIDSARVSRVAAVIEKRVGLKFSDQDIYVNVAGGIRLYEPAVDVALAMALYSARQNTPVKTNAAFIGEVSLSGEIR
PVRRLKTRLKTAYGLGFSTIYVPIGVEHDTPPPYTLRVVGTLAQTIAEIFSKAKA
>Mature_454_residues
AKKTERAFSCVGCGYVHPKWLGRCPECGEWNSFEETPSLSSGDVRAVKKASSSPVQAFPLCAVRAQDAQRISCGIAEFDR
VLGGGAVRRSAIMIGGEPGIGKSTLLLQIAAACGKSVLYVSGEESPGQIRGRADRLNIPIQNIELLCATRVEDVERVLNT
RCPTFVIVDSIQTVFSPEAGAIPMTINQLKYCANELIAWVKERDSVLFFTAHVTKDGNIAGPKVVEHMVDTVISFERNEE
DIRFLRALKNRFGSVDELGIFTMGENGLSAVQDTAGFFISTRQGMFPVGSATVPVCEGSRVFMVEIQALTVPAKSSVTRV
FSDRIDSARVSRVAAVIEKRVGLKFSDQDIYVNVAGGIRLYEPAVDVALAMALYSARQNTPVKTNAAFIGEVSLSGEIRP
VRRLKTRLKTAYGLGFSTIYVPIGVEHDTPPPYTLRVVGTLAQTIAEIFSKAKA

Specific function: May play a role in the repair of endogenous alkylation damage

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily

Homologues:

Organism=Escherichia coli, GI1790850, Length=432, Percent_Identity=37.7314814814815, Blast_Score=293, Evalue=2e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RADA_TREPA (O83985)

Other databases:

- EMBL:   AE000520
- PIR:   A71251
- RefSeq:   NP_219459.1
- ProteinModelPortal:   O83985
- GeneID:   2610878
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP1022
- NMPDR:   fig|243276.1.peg.1017
- TIGR:   TP_1022
- HOGENOM:   HBG286573
- OMA:   IGVFEMT
- ProtClustDB:   PRK11823
- BioCyc:   TPAL243276:TP_1022-MONOMER
- GO:   GO:0006508
- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568
- PRINTS:   PR01874
- SMART:   SM00382
- TIGRFAMs:   TIGR00416

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 49305; Mature: 49174

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKTERAFSCVGCGYVHPKWLGRCPECGEWNSFEETPSLSSGDVRAVKKASSSPVQAFP
CCCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC
LCAVRAQDAQRISCGIAEFDRVLGGGAVRRSAIMIGGEPGIGKSTLLLQIAAACGKSVLY
EEEEECCCCHHHHCCHHHHHHHHCCCHHEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEE
VSGEESPGQIRGRADRLNIPIQNIELLCATRVEDVERVLNTRCPTFVIVDSIQTVFSPEA
EECCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCC
GAIPMTINQLKYCANELIAWVKERDSVLFFTAHVTKDGNIAGPKVVEHMVDTVISFERNE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCH
EDIRFLRALKNRFGSVDELGIFTMGENGLSAVQDTAGFFISTRQGMFPVGSATVPVCEGS
HHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCEEEEECCC
RVFMVEIQALTVPAKSSVTRVFSDRIDSARVSRVAAVIEKRVGLKFSDQDIYVNVAGGIR
EEEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEECCCEEEEEEECCEE
LYEPAVDVALAMALYSARQNTPVKTNAAFIGEVSLSGEIRPVRRLKTRLKTAYGLGFSTI
EEHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEE
YVPIGVEHDTPPPYTLRVVGTLAQTIAEIFSKAKA
EEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKKTERAFSCVGCGYVHPKWLGRCPECGEWNSFEETPSLSSGDVRAVKKASSSPVQAFP
CCCHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCC
LCAVRAQDAQRISCGIAEFDRVLGGGAVRRSAIMIGGEPGIGKSTLLLQIAAACGKSVLY
EEEEECCCCHHHHCCHHHHHHHHCCCHHEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEE
VSGEESPGQIRGRADRLNIPIQNIELLCATRVEDVERVLNTRCPTFVIVDSIQTVFSPEA
EECCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCC
GAIPMTINQLKYCANELIAWVKERDSVLFFTAHVTKDGNIAGPKVVEHMVDTVISFERNE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCH
EDIRFLRALKNRFGSVDELGIFTMGENGLSAVQDTAGFFISTRQGMFPVGSATVPVCEGS
HHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCEEEEECCC
RVFMVEIQALTVPAKSSVTRVFSDRIDSARVSRVAAVIEKRVGLKFSDQDIYVNVAGGIR
EEEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEECCCEEEEEEECCEE
LYEPAVDVALAMALYSARQNTPVKTNAAFIGEVSLSGEIRPVRRLKTRLKTAYGLGFSTI
EEHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEE
YVPIGVEHDTPPPYTLRVVGTLAQTIAEIFSKAKA
EEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876