Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 189026186

GI number: 189026186

Start: 1046061

End: 1047290

Strand: Reverse

Name: macB [H]

Synonym: TPASS_0963

Alternate gene names: 189026186

Gene position: 1047290-1046061 (Counterclockwise)

Preceding gene: 189026187

Following gene: 189026185

Centisome position: 91.91

GC content: 52.36

Gene sequence:

>1230_bases
ATGGTGGGTGAGGATTTTTTGTATGCACTCCACACCTTTAATGCGCGCAGGGGACGTACTGTTCTTTCGCTTCTCGGTAT
TGTAGTCGGTATCACTTCTGTGGTGGTTGTGGCAACGTTGGGGAGCTCGCTGGGAGCGAGCGTGGAAAAGTTGTTCGAGG
AAGACAATAACAACATAATATCTGTTGCGCCCGTAGCCGCGCACGACGATGGGGTGCCGCGCGGGCAGCTTGTGCTCACC
GAGCACGTCCGCCACCATCTTAAAGAGCGCGTGGCAGGAGTGCAGGGGTTTTTTTATCTGAATTATTTGCAGGCTTCTGC
GAGTCGGCGGAGCTTGCACGCGGGAGCCGTCAGTGTGTTGGGGGTGGAACACGGTTGGCTTGCCGCCTCCGGTCTTACGG
TTTCCTATGGCTCTGACGTAAGCGTTATTGGTTACGCTGTGGGCACGCACAGCGTTATTCTTGGTAAACAAACGGCGGAG
GGGCTTTTCCCTGAGGGGAATGCGGTGGGAAAGACCATAACGCTCTACGTGCCTATTGGCCGAAACAAGGTCTTGCCGAT
GGTCGTGCGCGTTGCTGCAGTGCTCAAAGAAAAGGATGATTTTAGTTTCTCCTCCGCAGCGCAGGTGCTTATTCCACGGA
GTGTGCTGACAAGAGAGTTCTCTCGGCGTATTGCCGATGCAATGGATTTGAAAGTATACGATTCTGGATCGATCGCGCAT
GTTGAGGACAAAGTTAAGTCAGTGCTAACCAATCTGACCGGTAACGAGAAGGCCTTTGAAGTTTCTTCCCTCCATCTTAT
CGTTGAACAGATGCGGAGTTTTCTCCGGGCAATGAATATGGTCTTGACGGGCATCGCAGCTATTTCACTGATTGTCGGTG
GCATCGGTATTATGAACATCATGCTGGTGACGGTCGCCGAACGACGCCAGGAGATTGGGTTGCGGAAGGCACTGGGTGCT
TCGCGCATGCACGTGCTTCATCAGTTTTTGGTAGAATCGGCCACGTTAACGTTCGTAGGTGGTTTGTGCGGCGTTGTGCT
TGGCCTTTTACTGAGCGTGATTGTTATCGCCGGATTGAATGCGTTTGATTTTCAAATGACGTTTTCTCCTAGCGTAGTCG
GCATGTTTATTGCCTTTGCAGGGTCAGTAGTTATTGGGGTGTGTTTTGGGTCGTATCCAGCATTCCAAGCCGCGGGTCTT
GACCCAATCCAGTCTTTGGAAGACCGCTAG

Upstream 100 bases:

>100_bases
GTCACGCATGATCAGGGAGTAGGAGCTCTGGCTTCTCGCTCTCTCACGCTTAAAGATGGCAAGATAGTAGGAGATCACGT
GCGGGGTCACGGGGGAGCCG

Downstream 100 bases:

>100_bases
GCGATGTGTGTGCGCGTGCCTGTCCTGTGGCGTTGCCATGTGCGTGAAGTCAGGTTTCTGTAGGAGGGGAGAGGCGCGCG
CGTAGAGCGCACGGCTCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MVGEDFLYALHTFNARRGRTVLSLLGIVVGITSVVVVATLGSSLGASVEKLFEEDNNNIISVAPVAAHDDGVPRGQLVLT
EHVRHHLKERVAGVQGFFYLNYLQASASRRSLHAGAVSVLGVEHGWLAASGLTVSYGSDVSVIGYAVGTHSVILGKQTAE
GLFPEGNAVGKTITLYVPIGRNKVLPMVVRVAAVLKEKDDFSFSSAAQVLIPRSVLTREFSRRIADAMDLKVYDSGSIAH
VEDKVKSVLTNLTGNEKAFEVSSLHLIVEQMRSFLRAMNMVLTGIAAISLIVGGIGIMNIMLVTVAERRQEIGLRKALGA
SRMHVLHQFLVESATLTFVGGLCGVVLGLLLSVIVIAGLNAFDFQMTFSPSVVGMFIAFAGSVVIGVCFGSYPAFQAAGL
DPIQSLEDR

Sequences:

>Translated_409_residues
MVGEDFLYALHTFNARRGRTVLSLLGIVVGITSVVVVATLGSSLGASVEKLFEEDNNNIISVAPVAAHDDGVPRGQLVLT
EHVRHHLKERVAGVQGFFYLNYLQASASRRSLHAGAVSVLGVEHGWLAASGLTVSYGSDVSVIGYAVGTHSVILGKQTAE
GLFPEGNAVGKTITLYVPIGRNKVLPMVVRVAAVLKEKDDFSFSSAAQVLIPRSVLTREFSRRIADAMDLKVYDSGSIAH
VEDKVKSVLTNLTGNEKAFEVSSLHLIVEQMRSFLRAMNMVLTGIAAISLIVGGIGIMNIMLVTVAERRQEIGLRKALGA
SRMHVLHQFLVESATLTFVGGLCGVVLGLLLSVIVIAGLNAFDFQMTFSPSVVGMFIAFAGSVVIGVCFGSYPAFQAAGL
DPIQSLEDR
>Mature_409_residues
MVGEDFLYALHTFNARRGRTVLSLLGIVVGITSVVVVATLGSSLGASVEKLFEEDNNNIISVAPVAAHDDGVPRGQLVLT
EHVRHHLKERVAGVQGFFYLNYLQASASRRSLHAGAVSVLGVEHGWLAASGLTVSYGSDVSVIGYAVGTHSVILGKQTAE
GLFPEGNAVGKTITLYVPIGRNKVLPMVVRVAAVLKEKDDFSFSSAAQVLIPRSVLTREFSRRIADAMDLKVYDSGSIAH
VEDKVKSVLTNLTGNEKAFEVSSLHLIVEQMRSFLRAMNMVLTGIAAISLIVGGIGIMNIMLVTVAERRQEIGLRKALGA
SRMHVLHQFLVESATLTFVGGLCGVVLGLLLSVIVIAGLNAFDFQMTFSPSVVGMFIAFAGSVVIGVCFGSYPAFQAAGL
DPIQSLEDR

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=412, Percent_Identity=30.0970873786408, Blast_Score=137, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43579; Mature: 43579

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGEDFLYALHTFNARRGRTVLSLLGIVVGITSVVVVATLGSSLGASVEKLFEEDNNNII
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEE
SVAPVAAHDDGVPRGQLVLTEHVRHHLKERVAGVQGFFYLNYLQASASRRSLHAGAVSVL
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
GVEHGWLAASGLTVSYGSDVSVIGYAVGTHSVILGKQTAEGLFPEGNAVGKTITLYVPIG
ECCCCEEEECCEEEECCCCCEEEEEECCCCEEEEECHHHCCCCCCCCCCCCEEEEEEECC
RNKVLPMVVRVAAVLKEKDDFSFSSAAQVLIPRSVLTREFSRRIADAMDLKVYDSGSIAH
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHH
VEDKVKSVLTNLTGNEKAFEVSSLHLIVEQMRSFLRAMNMVLTGIAAISLIVGGIGIMNI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVTVAERRQEIGLRKALGASRMHVLHQFLVESATLTFVGGLCGVVLGLLLSVIVIAGLN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AFDFQMTFSPSVVGMFIAFAGSVVIGVCFGSYPAFQAAGLDPIQSLEDR
CEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHCCCC
>Mature Secondary Structure
MVGEDFLYALHTFNARRGRTVLSLLGIVVGITSVVVVATLGSSLGASVEKLFEEDNNNII
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEE
SVAPVAAHDDGVPRGQLVLTEHVRHHLKERVAGVQGFFYLNYLQASASRRSLHAGAVSVL
EEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
GVEHGWLAASGLTVSYGSDVSVIGYAVGTHSVILGKQTAEGLFPEGNAVGKTITLYVPIG
ECCCCEEEECCEEEECCCCCEEEEEECCCCEEEEECHHHCCCCCCCCCCCCEEEEEEECC
RNKVLPMVVRVAAVLKEKDDFSFSSAAQVLIPRSVLTREFSRRIADAMDLKVYDSGSIAH
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHH
VEDKVKSVLTNLTGNEKAFEVSSLHLIVEQMRSFLRAMNMVLTGIAAISLIVGGIGIMNI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVTVAERRQEIGLRKALGASRMHVLHQFLVESATLTFVGGLCGVVLGLLLSVIVIAGLN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AFDFQMTFSPSVVGMFIAFAGSVVIGVCFGSYPAFQAAGLDPIQSLEDR
CEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA