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The map label for this gene is macB [H]

Identifier: 189026185

GI number: 189026185

Start: 1044718

End: 1045950

Strand: Reverse

Name: macB [H]

Synonym: TPASS_0962

Alternate gene names: 189026185

Gene position: 1045950-1044718 (Counterclockwise)

Preceding gene: 189026186

Following gene: 189026184

Centisome position: 91.79

GC content: 50.77

Gene sequence:

>1233_bases
ATGCTTGAAGATATCGTGAACACCCTGTTGTATTTCAGGCAGCGTGTGCTGCGGACGACCCTTTCGTTCCTCGGTATTGC
GGTAGGGGTTGCGTCGGTAGTGGTAATTACCTCGATCGGCGAGTCTCTCTACGCGAGTCTTGCCCAGAGTGTTGGCGAGG
GCGAGCGCCGACTCATTCGAGTCAGGCCAGAGTGGGATTATGTGAAGAACGAAATCATGTTTCAGCCGACTGAGTCGTAT
CGGACGCGACTTGTACAAAGTAGCGAGGATATAGAGGGAGTGTTTTACAATTCTTCCCTCAAGGCACTTATTTCTTCTCC
TCACACAGGGGGAAAGGAACGGAACATTACGGGAGTAGAGCCGCGGTGGCTGGAGTTAAAAGATTTTAAGCTTGAGTATG
GGACGTTCTTTTCTCCAGCGGACTTTAAGACCCATCGTCACTGTGCGGTGATTGGCGGTTTGCTTGCGCAAGAATTATTT
CCTGAAGGGAATGCATTGGGTAAACGTATGACTGTGACCATACTTTCCCGGGCGTCGGGTGCAGAACGTGCACTGTCTTT
CCCATTTGAAATCGTAGGCGTCTTGCAGGAAAAGGGGAGTTTGATTAGTGGCATTCCTTCGTATCGGGTTTTTGTCCCCC
GTGAGTTTATTTCTCTAGAAATGGGTGCAGGTCGTGTGGCAGACGCGGTGGAGGTGTGCGTACGCGATGTGCAGGTTATT
GCCGCAGCGGAAAAACGTATCCGGGAGTTTTCGGACTTTTTCTCTAACAAATCGGGTTCTGTGAGCCTTTGGTCCGGTGC
GGGGGAAATAAAAAGTTTTCGCAGCGTTCTGAGTATGGTGAGTGTAGTGCTGTCGGTTGTGGCTGCAGTCTCGCTGATTG
TCGGTGGCATAAATATCATGAACATTATGGTAGTAACCGTAACCGAGCGTCGCAGAGAAATCGGTCTCCGCAAGGCCGTC
GGTGCGACGTGCGCAACAATAGTTCAGCAGTTTTTGCTCGAGGCGGTGCTTTTAACCCTGGCGGGGTGCGTGTGTGGCCT
TATTCTTGGGATGGTGCTCAGTTATGGGCTCTTTTCCGTGTTTTCTCCAGAGGGGATAACAGTTGTTTTCAGTCTGAGCA
CTGCGGGTATGCGTACAGCCTTCTTTATGTCATTGGGAGCGGGGATTTTCTTTGGATTAAAACCAGCGCTGCAGGCCTCA
AGACTCGATCCTATTATTGCACTTGCTCAGTGA

Upstream 100 bases:

>100_bases
TGCGCGTGCCTGTCCTGTGGCGTTGCCATGTGCGTGAAGTCAGGTTTCTGTAGGAGGGGAGAGGCGCGCGCGTAGAGCGC
ACGGCTCTGCAAAGAGGGAT

Downstream 100 bases:

>100_bases
ATATCAAAAAAGTAGTCACACTGACAAAAGAATTTTCTTGATTCCCCTTTTCTATCTCCCGATACCAGGGGGAGCGGAGG
GGCGTATGATCCGAGGGTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MLEDIVNTLLYFRQRVLRTTLSFLGIAVGVASVVVITSIGESLYASLAQSVGEGERRLIRVRPEWDYVKNEIMFQPTESY
RTRLVQSSEDIEGVFYNSSLKALISSPHTGGKERNITGVEPRWLELKDFKLEYGTFFSPADFKTHRHCAVIGGLLAQELF
PEGNALGKRMTVTILSRASGAERALSFPFEIVGVLQEKGSLISGIPSYRVFVPREFISLEMGAGRVADAVEVCVRDVQVI
AAAEKRIREFSDFFSNKSGSVSLWSGAGEIKSFRSVLSMVSVVLSVVAAVSLIVGGINIMNIMVVTVTERRREIGLRKAV
GATCATIVQQFLLEAVLLTLAGCVCGLILGMVLSYGLFSVFSPEGITVVFSLSTAGMRTAFFMSLGAGIFFGLKPALQAS
RLDPIIALAQ

Sequences:

>Translated_410_residues
MLEDIVNTLLYFRQRVLRTTLSFLGIAVGVASVVVITSIGESLYASLAQSVGEGERRLIRVRPEWDYVKNEIMFQPTESY
RTRLVQSSEDIEGVFYNSSLKALISSPHTGGKERNITGVEPRWLELKDFKLEYGTFFSPADFKTHRHCAVIGGLLAQELF
PEGNALGKRMTVTILSRASGAERALSFPFEIVGVLQEKGSLISGIPSYRVFVPREFISLEMGAGRVADAVEVCVRDVQVI
AAAEKRIREFSDFFSNKSGSVSLWSGAGEIKSFRSVLSMVSVVLSVVAAVSLIVGGINIMNIMVVTVTERRREIGLRKAV
GATCATIVQQFLLEAVLLTLAGCVCGLILGMVLSYGLFSVFSPEGITVVFSLSTAGMRTAFFMSLGAGIFFGLKPALQAS
RLDPIIALAQ
>Mature_410_residues
MLEDIVNTLLYFRQRVLRTTLSFLGIAVGVASVVVITSIGESLYASLAQSVGEGERRLIRVRPEWDYVKNEIMFQPTESY
RTRLVQSSEDIEGVFYNSSLKALISSPHTGGKERNITGVEPRWLELKDFKLEYGTFFSPADFKTHRHCAVIGGLLAQELF
PEGNALGKRMTVTILSRASGAERALSFPFEIVGVLQEKGSLISGIPSYRVFVPREFISLEMGAGRVADAVEVCVRDVQVI
AAAEKRIREFSDFFSNKSGSVSLWSGAGEIKSFRSVLSMVSVVLSVVAAVSLIVGGINIMNIMVVTVTERRREIGLRKAV
GATCATIVQQFLLEAVLLTLAGCVCGLILGMVLSYGLFSVFSPEGITVVFSLSTAGMRTAFFMSLGAGIFFGLKPALQAS
RLDPIIALAQ

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=434, Percent_Identity=27.6497695852535, Blast_Score=131, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44606; Mature: 44606

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEDIVNTLLYFRQRVLRTTLSFLGIAVGVASVVVITSIGESLYASLAQSVGEGERRLIR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VRPEWDYVKNEIMFQPTESYRTRLVQSSEDIEGVFYNSSLKALISSPHTGGKERNITGVE
ECCCHHHHCCCEEECCCHHHHHHHHCCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCCCC
PRWLELKDFKLEYGTFFSPADFKTHRHCAVIGGLLAQELFPEGNALGKRMTVTILSRASG
CCEEEHEECEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHCCC
AERALSFPFEIVGVLQEKGSLISGIPSYRVFVPREFISLEMGAGRVADAVEVCVRDVQVI
CHHHHCCCHHHHHHHHHCCCHHCCCCCCEEEECHHHHHEECCCCHHHHHHHHHHHHHHHH
AAAEKRIREFSDFFSNKSGSVSLWSGAGEIKSFRSVLSMVSVVLSVVAAVSLIVGGINIM
HHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
NIMVVTVTERRREIGLRKAVGATCATIVQQFLLEAVLLTLAGCVCGLILGMVLSYGLFSV
HEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSPEGITVVFSLSTAGMRTAFFMSLGAGIFFGLKPALQASRLDPIIALAQ
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEECC
>Mature Secondary Structure
MLEDIVNTLLYFRQRVLRTTLSFLGIAVGVASVVVITSIGESLYASLAQSVGEGERRLIR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VRPEWDYVKNEIMFQPTESYRTRLVQSSEDIEGVFYNSSLKALISSPHTGGKERNITGVE
ECCCHHHHCCCEEECCCHHHHHHHHCCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCCCC
PRWLELKDFKLEYGTFFSPADFKTHRHCAVIGGLLAQELFPEGNALGKRMTVTILSRASG
CCEEEHEECEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHCCC
AERALSFPFEIVGVLQEKGSLISGIPSYRVFVPREFISLEMGAGRVADAVEVCVRDVQVI
CHHHHCCCHHHHHHHHHCCCHHCCCCCCEEEECHHHHHEECCCCHHHHHHHHHHHHHHHH
AAAEKRIREFSDFFSNKSGSVSLWSGAGEIKSFRSVLSMVSVVLSVVAAVSLIVGGINIM
HHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEE
NIMVVTVTERRREIGLRKAVGATCATIVQQFLLEAVLLTLAGCVCGLILGMVLSYGLFSV
HEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSPEGITVVFSLSTAGMRTAFFMSLGAGIFFGLKPALQASRLDPIIALAQ
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA