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The map label for this gene is bcd [H]

Identifier: 188586496

GI number: 188586496

Start: 1970308

End: 1971447

Strand: Reverse

Name: bcd [H]

Synonym: Nther_1881

Alternate gene names: 188586496

Gene position: 1971447-1970308 (Counterclockwise)

Preceding gene: 188586497

Following gene: 188586495

Centisome position: 62.28

GC content: 39.12

Gene sequence:

>1140_bases
TTGAATTTTGAATTATCGAATGAACACAAAATGGTTCAAAAAACAATACGCGAGTTTGCTCAAAACGAAGTAGAGCCAAT
TGCAGCAGAGATAGATGAAACCGAGAGATTTCCGACAGAAAATGTAGATCAGATGCAAAGATATAAAATGATGGGAGTAA
ATGTTCCGAAAGAGTACGGTGGTGCAGGTGGTGATGAGTTAGCCTATGCCATAACAGTAGAAGAGCTCTCAAGAGCTTGT
GCAACTACTGGTATCATTTGTTCTGCTCATACGTCATTAGCATGCTGGCCCATTTTAAAGTATGGAACTGAAGAGCAAAA
GCAGAAATATCTAAAACCATTAGCATCAGGTGAAAAAATTGGAGCTTTTGGCCTCACAGAGCCTAATGCAGGTAGTGATG
CTGGTTCCCAAGAGACAAGAGCAGAACTAAAAGACGATCATTATCTAATAAATGGCACAAAAATCTTTATTACAAATGGT
GATGAAGCAGATACTTATATCGTCTTTGCAATGACAGAACCCGATAAAGGTGTAAAAGGAATCTCAGCCTTTATAGTAGA
TAGAGATACTCCTGGCTTTTCAGTAGGTAAACGTGAAAAGAAAATGGGCATCAAAGGTTCAGCTACAACTGAACTAATCT
TTGAAAATATGAAGGTACCGAAAGAAAATCTATTAGGCAAAGAAGGCCAAGGTTTCAAGATAGCTATGAAAACTTTAGAT
GGCGGTAGGATAGGAGTAGCTGCACAAGCCCTGGGGATAGCACAAGGCGCTTTAGATGAGACAGTAAACTACACCAAAGA
AAGAGAACAATTTAACAGGCCAATAGCTAAATTTCAAGGACTTCAATTTGAAATGGCAGACATGTCCACTCAAGTAGAAG
CAGCAAGACTATTGGTATATAGAGCAGCTATGGCAAAAGCGCAAGGTAAACCCTACACTAAAGAAGCAGCTATGGCCAAG
CTATATGCTTCAGAGGTAGCTATGCATGTAGCAAATAAAGCCATTCAACTACATGGTGGTTACGGATACACCAAGGACTA
TCCAGTAGAACGAATGTTAAGAGATGCAAAAATCACAGAGATCTATGAAGGAACATCAGAAGTTCAAAGAATGGTAATTT
CAGGAGATCTGTTAAAATAG

Upstream 100 bases:

>100_bases
TTACCCCCCTGAATTCAAACGGCTGAGCAGTGGGGTAACTGTGATAGTTCAATGCTATATAACAAAATATTAACGTAGAA
TATTAAGGAGGGAGTTAACC

Downstream 100 bases:

>100_bases
CAAAAGTAAACAAGCTCACTACTAGTTTTCTAGTCTATAATAAGTTGTCAAAGGAGGAATTAAATTGAATATAATAGTTT
GTGTAAAACAAGTGCCGGAC

Product: butyryl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNFELSNEHKMVQKTIREFAQNEVEPIAAEIDETERFPTENVDQMQRYKMMGVNVPKEYGGAGGDELAYAITVEELSRAC
ATTGIICSAHTSLACWPILKYGTEEQKQKYLKPLASGEKIGAFGLTEPNAGSDAGSQETRAELKDDHYLINGTKIFITNG
DEADTYIVFAMTEPDKGVKGISAFIVDRDTPGFSVGKREKKMGIKGSATTELIFENMKVPKENLLGKEGQGFKIAMKTLD
GGRIGVAAQALGIAQGALDETVNYTKEREQFNRPIAKFQGLQFEMADMSTQVEAARLLVYRAAMAKAQGKPYTKEAAMAK
LYASEVAMHVANKAIQLHGGYGYTKDYPVERMLRDAKITEIYEGTSEVQRMVISGDLLK

Sequences:

>Translated_379_residues
MNFELSNEHKMVQKTIREFAQNEVEPIAAEIDETERFPTENVDQMQRYKMMGVNVPKEYGGAGGDELAYAITVEELSRAC
ATTGIICSAHTSLACWPILKYGTEEQKQKYLKPLASGEKIGAFGLTEPNAGSDAGSQETRAELKDDHYLINGTKIFITNG
DEADTYIVFAMTEPDKGVKGISAFIVDRDTPGFSVGKREKKMGIKGSATTELIFENMKVPKENLLGKEGQGFKIAMKTLD
GGRIGVAAQALGIAQGALDETVNYTKEREQFNRPIAKFQGLQFEMADMSTQVEAARLLVYRAAMAKAQGKPYTKEAAMAK
LYASEVAMHVANKAIQLHGGYGYTKDYPVERMLRDAKITEIYEGTSEVQRMVISGDLLK
>Mature_379_residues
MNFELSNEHKMVQKTIREFAQNEVEPIAAEIDETERFPTENVDQMQRYKMMGVNVPKEYGGAGGDELAYAITVEELSRAC
ATTGIICSAHTSLACWPILKYGTEEQKQKYLKPLASGEKIGAFGLTEPNAGSDAGSQETRAELKDDHYLINGTKIFITNG
DEADTYIVFAMTEPDKGVKGISAFIVDRDTPGFSVGKREKKMGIKGSATTELIFENMKVPKENLLGKEGQGFKIAMKTLD
GGRIGVAAQALGIAQGALDETVNYTKEREQFNRPIAKFQGLQFEMADMSTQVEAARLLVYRAAMAKAQGKPYTKEAAMAK
LYASEVAMHVANKAIQLHGGYGYTKDYPVERMLRDAKITEIYEGTSEVQRMVISGDLLK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=53.4391534391534, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI4501859, Length=370, Percent_Identity=45.1351351351351, Blast_Score=348, Evalue=4e-96,
Organism=Homo sapiens, GI226958412, Length=373, Percent_Identity=43.1635388739946, Blast_Score=304, Evalue=1e-82,
Organism=Homo sapiens, GI7656849, Length=376, Percent_Identity=41.4893617021277, Blast_Score=301, Evalue=7e-82,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=39.9470899470899, Blast_Score=288, Evalue=6e-78,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=39.9470899470899, Blast_Score=288, Evalue=6e-78,
Organism=Homo sapiens, GI226958414, Length=332, Percent_Identity=44.578313253012, Blast_Score=284, Evalue=8e-77,
Organism=Homo sapiens, GI21361497, Length=376, Percent_Identity=41.4893617021277, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=34.2175066312997, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI4557235, Length=374, Percent_Identity=37.7005347593583, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI76496475, Length=374, Percent_Identity=37.7005347593583, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI4503943, Length=373, Percent_Identity=32.171581769437, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI7669494, Length=363, Percent_Identity=32.5068870523416, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI211971008, Length=333, Percent_Identity=31.2312312312312, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI48976061, Length=333, Percent_Identity=31.2312312312312, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI38505218, Length=386, Percent_Identity=25.6476683937824, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI218563752, Length=227, Percent_Identity=29.5154185022026, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI87081958, Length=382, Percent_Identity=30.1047120418848, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=28.5340314136126, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI87082384, Length=311, Percent_Identity=25.7234726688103, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87081702, Length=372, Percent_Identity=25.8064516129032, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17508101, Length=371, Percent_Identity=41.5094339622642, Blast_Score=318, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI17506239, Length=360, Percent_Identity=43.3333333333333, Blast_Score=317, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=43.1937172774869, Blast_Score=304, Evalue=6e-83,
Organism=Caenorhabditis elegans, GI17534899, Length=382, Percent_Identity=43.455497382199, Blast_Score=303, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=39.9470899470899, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=37.5328083989501, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI71985184, Length=351, Percent_Identity=43.5897435897436, Blast_Score=268, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI71990804, Length=275, Percent_Identity=45.8181818181818, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=38.544474393531, Blast_Score=262, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI71985192, Length=298, Percent_Identity=43.2885906040268, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=32.5268817204301, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI32563615, Length=229, Percent_Identity=43.2314410480349, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71982178, Length=272, Percent_Identity=35.6617647058824, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17551932, Length=374, Percent_Identity=30.2139037433155, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17505929, Length=368, Percent_Identity=29.6195652173913, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17531909, Length=237, Percent_Identity=35.4430379746835, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17562446, Length=343, Percent_Identity=30.9037900874636, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17531913, Length=173, Percent_Identity=34.1040462427746, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI86563381, Length=278, Percent_Identity=28.7769784172662, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=278, Percent_Identity=28.7769784172662, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17540912, Length=338, Percent_Identity=23.9644970414201, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=53.6, Blast_Score=413, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=48, Blast_Score=358, Evalue=4e-99,
Organism=Drosophila melanogaster, GI24666513, Length=370, Percent_Identity=43.7837837837838, Blast_Score=325, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=41.0526315789474, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=40.9448818897638, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI281363737, Length=362, Percent_Identity=39.5027624309392, Blast_Score=241, Evalue=7e-64,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=31.1345646437995, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24652780, Length=349, Percent_Identity=24.3553008595989, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 41737; Mature: 41737

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFELSNEHKMVQKTIREFAQNEVEPIAAEIDETERFPTENVDQMQRYKMMGVNVPKEYG
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHC
GAGGDELAYAITVEELSRACATTGIICSAHTSLACWPILKYGTEEQKQKYLKPLASGEKI
CCCCCCEEEEEEHHHHHHHHHHHCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC
GAFGLTEPNAGSDAGSQETRAELKDDHYLINGTKIFITNGDEADTYIVFAMTEPDKGVKG
CEECCCCCCCCCCCCCHHHHHHHCCCEEEEECEEEEEECCCCCCEEEEEEEECCCCCCCC
ISAFIVDRDTPGFSVGKREKKMGIKGSATTELIFENMKVPKENLLGKEGQGFKIAMKTLD
EEEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECC
GGRIGVAAQALGIAQGALDETVNYTKEREQFNRPIAKFQGLQFEMADMSTQVEAARLLVY
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEHHHHHHHHHHHHHHHH
RAAMAKAQGKPYTKEAAMAKLYASEVAMHVANKAIQLHGGYGYTKDYPVERMLRDAKITE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHH
IYEGTSEVQRMVISGDLLK
HHCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNFELSNEHKMVQKTIREFAQNEVEPIAAEIDETERFPTENVDQMQRYKMMGVNVPKEYG
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHC
GAGGDELAYAITVEELSRACATTGIICSAHTSLACWPILKYGTEEQKQKYLKPLASGEKI
CCCCCCEEEEEEHHHHHHHHHHHCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC
GAFGLTEPNAGSDAGSQETRAELKDDHYLINGTKIFITNGDEADTYIVFAMTEPDKGVKG
CEECCCCCCCCCCCCCHHHHHHHCCCEEEEECEEEEEECCCCCCEEEEEEEECCCCCCCC
ISAFIVDRDTPGFSVGKREKKMGIKGSATTELIFENMKVPKENLLGKEGQGFKIAMKTLD
EEEEEEECCCCCCCCCCHHHHCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCEEEEEEECC
GGRIGVAAQALGIAQGALDETVNYTKEREQFNRPIAKFQGLQFEMADMSTQVEAARLLVY
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEHHHHHHHHHHHHHHHH
RAAMAKAQGKPYTKEAAMAKLYASEVAMHVANKAIQLHGGYGYTKDYPVERMLRDAKITE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHH
IYEGTSEVQRMVISGDLLK
HHCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]