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The map label for this gene is tldD [C]

Identifier: 188586461

GI number: 188586461

Start: 1924058

End: 1925437

Strand: Reverse

Name: tldD [C]

Synonym: Nther_1846

Alternate gene names: 188586461

Gene position: 1925437-1924058 (Counterclockwise)

Preceding gene: 188586462

Following gene: 188586460

Centisome position: 60.82

GC content: 35.14

Gene sequence:

>1380_bases
ATGAAATTGGAGTATTTAAAGACCTTTAAGAATTATCTAGATGAACATGCGGAGCTTCGATTACAACAAAACACATCAGT
TTCTTTAGTACTGGTTAATGGAAACTTAGTCAGAAACCAAAAAAACACTTCTAGTGGTATATCTTCTAGGGTATATAATC
AAGGTTATTTTGGATTTGCTTCTAGTCCTAAAACAGATGAAAAAACAGTTAAGGATATCATTAAAAGATCAAAGACTAAC
GCTAGTTTGCTAGCCAAGTTAGAAAACTCCAATAAAGCACAATTATCTGGAGAAAGTTTTGAAGTCATCAAAGACTTTTC
TACTGACAAAACTAGAGTATCAAGAAAAGACATGCTGGAATTTTTGAAAGATTTACATGAATATACAGCAAAAAACTATC
CAGACATTAAATCAGACACTTTTGTTATCAATAATTTAGATATGGAAAAAAACCTGTTAACTTCTTTCGGAGCTTCTGGT
CACACAATGATTCCGCGATCGTTGTTGATAATCAGCCTTTCTGTTGAAAAAGATGGTAACACGTATGATACTTACGACGT
TTTTGGTGGATTAGGCCAATATGAAGACTATTTTGATAATCCTGAAGATTTTTACGAAAAGATTGATGAAGTATATCGTA
AAGTTAAGGAGAAATCAGAAGGTGTCTATCCTGAAGCTGGCTATAAAGATGTGATTCTCGATTCTAAACTAGCTGGTATT
TTAGCTCACGAAGCCATTGGGCATACGACGGAAGCCGATATGGTGAAAAGTGGTTCTGTTGCCAAGGATTATCTTAATGA
AAAAGTTGCCAGTGATATCGTGAATTTAGCTGATTTTGCTTATGAGTACAATAATGAAGTTTGTCCCATGCCTGTGTACA
TAGATGATGAAGGAACGAGACCTGAAGATGCCTTCATTATCGAAAATGGGATTTTAAAGAGGTATATGAATAATAAAGAT
TTGTCTATAGATTTAAATGAGCAGCCAACTGGTAATGCCAGGGCCTATGGTTACTCAGATGAACCCTTAGTTAGAATGAG
AAATACGGCTATCTTACCTGGTTCAGATAGACTAGAGGATATGATTGCATCTATTGATGATGGATATTATTTAGTCAAGC
CGAGTAATGGACAGGCTGACTCTACAAGTGAATTTATGTTTGGTGTACCAAATGGTTATGAGATTAAAAATGGCAAACTG
GGAAGAGCCATTAAAGATACAACAATTTCAGGCATTGCTTTTGATGTCCTTAAAACAGTTACCATGATTTCAGATGAAAT
GACATGGTCAAATGCTGGGATGTGTGGAAAAAAACAAGTGATACCAGTTGGAATGGGCGGACCTGCTATAAAGTGTAAAA
TTAATATAGGAGGTAGGTAA

Upstream 100 bases:

>100_bases
CGCCTAAAAACAAAACATCTAATTGATGTTAAAAAAGGATTTTTACTATAATTACAGAAATTTTATATATTGGATGATTT
TTGATTGGAGGGATATTGAC

Downstream 100 bases:

>100_bases
TATGGAACTATTAAATAAATGTTTGACTAATTTAAAAGAAAAGGGTGCCGATAAATCTGAAGTATATTTAACAAAAGAAA
TTAAACAAGAGATGAATATC

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKLEYLKTFKNYLDEHAELRLQQNTSVSLVLVNGNLVRNQKNTSSGISSRVYNQGYFGFASSPKTDEKTVKDIIKRSKTN
ASLLAKLENSNKAQLSGESFEVIKDFSTDKTRVSRKDMLEFLKDLHEYTAKNYPDIKSDTFVINNLDMEKNLLTSFGASG
HTMIPRSLLIISLSVEKDGNTYDTYDVFGGLGQYEDYFDNPEDFYEKIDEVYRKVKEKSEGVYPEAGYKDVILDSKLAGI
LAHEAIGHTTEADMVKSGSVAKDYLNEKVASDIVNLADFAYEYNNEVCPMPVYIDDEGTRPEDAFIIENGILKRYMNNKD
LSIDLNEQPTGNARAYGYSDEPLVRMRNTAILPGSDRLEDMIASIDDGYYLVKPSNGQADSTSEFMFGVPNGYEIKNGKL
GRAIKDTTISGIAFDVLKTVTMISDEMTWSNAGMCGKKQVIPVGMGGPAIKCKINIGGR

Sequences:

>Translated_459_residues
MKLEYLKTFKNYLDEHAELRLQQNTSVSLVLVNGNLVRNQKNTSSGISSRVYNQGYFGFASSPKTDEKTVKDIIKRSKTN
ASLLAKLENSNKAQLSGESFEVIKDFSTDKTRVSRKDMLEFLKDLHEYTAKNYPDIKSDTFVINNLDMEKNLLTSFGASG
HTMIPRSLLIISLSVEKDGNTYDTYDVFGGLGQYEDYFDNPEDFYEKIDEVYRKVKEKSEGVYPEAGYKDVILDSKLAGI
LAHEAIGHTTEADMVKSGSVAKDYLNEKVASDIVNLADFAYEYNNEVCPMPVYIDDEGTRPEDAFIIENGILKRYMNNKD
LSIDLNEQPTGNARAYGYSDEPLVRMRNTAILPGSDRLEDMIASIDDGYYLVKPSNGQADSTSEFMFGVPNGYEIKNGKL
GRAIKDTTISGIAFDVLKTVTMISDEMTWSNAGMCGKKQVIPVGMGGPAIKCKINIGGR
>Mature_459_residues
MKLEYLKTFKNYLDEHAELRLQQNTSVSLVLVNGNLVRNQKNTSSGISSRVYNQGYFGFASSPKTDEKTVKDIIKRSKTN
ASLLAKLENSNKAQLSGESFEVIKDFSTDKTRVSRKDMLEFLKDLHEYTAKNYPDIKSDTFVINNLDMEKNLLTSFGASG
HTMIPRSLLIISLSVEKDGNTYDTYDVFGGLGQYEDYFDNPEDFYEKIDEVYRKVKEKSEGVYPEAGYKDVILDSKLAGI
LAHEAIGHTTEADMVKSGSVAKDYLNEKVASDIVNLADFAYEYNNEVCPMPVYIDDEGTRPEDAFIIENGILKRYMNNKD
LSIDLNEQPTGNARAYGYSDEPLVRMRNTAILPGSDRLEDMIASIDDGYYLVKPSNGQADSTSEFMFGVPNGYEIKNGKL
GRAIKDTTISGIAFDVLKTVTMISDEMTWSNAGMCGKKQVIPVGMGGPAIKCKINIGGR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=304, Percent_Identity=33.5526315789474, Blast_Score=144, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51207; Mature: 51207

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEYLKTFKNYLDEHAELRLQQNTSVSLVLVNGNLVRNQKNTSSGISSRVYNQGYFGFA
CCHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCEEEECCCCCCCHHHHHHHCCCCCCCC
SSPKTDEKTVKDIIKRSKTNASLLAKLENSNKAQLSGESFEVIKDFSTDKTRVSRKDMLE
CCCCCHHHHHHHHHHHCCCCHHHEEEECCCCCCEECCCHHHHHHHCCCCHHHHHHHHHHH
FLKDLHEYTAKNYPDIKSDTFVINNLDMEKNLLTSFGASGHTMIPRSLLIISLSVEKDGN
HHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCC
TYDTYDVFGGLGQYEDYFDNPEDFYEKIDEVYRKVKEKSEGVYPEAGYKDVILDSKLAGI
CCCHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHH
LAHEAIGHTTEADMVKSGSVAKDYLNEKVASDIVNLADFAYEYNNEVCPMPVYIDDEGTR
HHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
PEDAFIIENGILKRYMNNKDLSIDLNEQPTGNARAYGYSDEPLVRMRNTAILPGSDRLED
CCCEEEECHHHHHHHCCCCCEEEECCCCCCCCCEEECCCCCCCEEECCCEECCCCHHHHH
MIASIDDGYYLVKPSNGQADSTSEFMFGVPNGYEIKNGKLGRAIKDTTISGIAFDVLKTV
HHHHCCCCEEEEECCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHCHHHHHHHHHHHHH
TMISDEMTWSNAGMCGKKQVIPVGMGGPAIKCKINIGGR
HHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCC
>Mature Secondary Structure
MKLEYLKTFKNYLDEHAELRLQQNTSVSLVLVNGNLVRNQKNTSSGISSRVYNQGYFGFA
CCHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCEEEECCCCCCCHHHHHHHCCCCCCCC
SSPKTDEKTVKDIIKRSKTNASLLAKLENSNKAQLSGESFEVIKDFSTDKTRVSRKDMLE
CCCCCHHHHHHHHHHHCCCCHHHEEEECCCCCCEECCCHHHHHHHCCCCHHHHHHHHHHH
FLKDLHEYTAKNYPDIKSDTFVINNLDMEKNLLTSFGASGHTMIPRSLLIISLSVEKDGN
HHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCC
TYDTYDVFGGLGQYEDYFDNPEDFYEKIDEVYRKVKEKSEGVYPEAGYKDVILDSKLAGI
CCCHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECHHHHHH
LAHEAIGHTTEADMVKSGSVAKDYLNEKVASDIVNLADFAYEYNNEVCPMPVYIDDEGTR
HHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
PEDAFIIENGILKRYMNNKDLSIDLNEQPTGNARAYGYSDEPLVRMRNTAILPGSDRLED
CCCEEEECHHHHHHHCCCCCEEEECCCCCCCCCEEECCCCCCCEEECCCEECCCCHHHHH
MIASIDDGYYLVKPSNGQADSTSEFMFGVPNGYEIKNGKLGRAIKDTTISGIAFDVLKTV
HHHHCCCCEEEEECCCCCCCCCCCEEEECCCCCEECCCCCCCHHHHCHHHHHHHHHHHHH
TMISDEMTWSNAGMCGKKQVIPVGMGGPAIKCKINIGGR
HHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]