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The map label for this gene is yfbQ [C]

Identifier: 188586459

GI number: 188586459

Start: 1921267

End: 1922466

Strand: Reverse

Name: yfbQ [C]

Synonym: Nther_1844

Alternate gene names: 188586459

Gene position: 1922466-1921267 (Counterclockwise)

Preceding gene: 188586460

Following gene: 188586458

Centisome position: 60.73

GC content: 35.75

Gene sequence:

>1200_bases
ATGCTATCTGATAAAGCAAAACAAATAACTCCTTCACCAACTTTAAGTATTAATGCAAAGGCAAAGGAGCTTAAGAACCA
AGGTATTAATGTAATTAGTTTCAGTCAGGGTGAACCGGATTTTAATACTCCTGATCATATAAAAAAAGCTGCTATCACAG
CGATTGAGGATAATTTCACCCGTTATACACCGGCTAGTGGAATGATAGAATTAAAACAGGCAATTTCTGAAAAATTTCTT
AGAGACAATGATTTAAGTTATGACCCAAATCAAATAATTATTTCTAATGGTGCTAAACATGCCTTGTTAAACGTTATGAC
TGCAATTTTGAACATTGGTGATGAGGTTTTAATACCAACACCCTATTGGGTAAGTTATCCTGAACTTGTAAAACTTGTTG
ACGGGTGTCCCGTTCCAGTTAAAGCTAGTGCTAGCAATAATTTTAAAGTCACTCCAGAGGATCTAAAAAAATACTTGAGT
TCAAAAACTCGTGCAATAATTATAAATACACCTACAAACCCGACTGGTCAGATTTATTCTCAAAAAGAATTAGAAAAGAT
AGGTGAATTTGCCTTAAATAATGGTTTGTATATTATATCGGATGAAGTTTATGAATATATGTCTTATAACGGTCAACAAC
ACATCAGTATTGCTTCACTTAGTGAAGAACTTAAACAACAAACAGTTGTTTTGAATGGCGTTTCAAAAAGTTATGCTATG
ACTGGTTGGAGAATAGGGTACTCAGCTGCTCCGAAAGAACTGGCTCATGGGATGAGTGCAATTCAAAGTCATGGGACATC
TAATCCATCTTCCATTTCTCAAAAGGGAGCCCTAGCAGCTATACGGGGACCTCAAAACTGTGTCAATGAAATGGTTGCCC
AACTTGATGAACGTAGAAAGTTCATGTATGAAAGATTATCTCAAATTCCTGGATTCCAGGCTTTAGAACCAGTAGGGTCA
TTTTATTTATTTGCTAGTGTACGAGAATTGATTGGAAAAAGTTTAGATGAAAAAATTATTAGGGATAGCCACGATTTTGC
AGAACTGTTACTTGACAAGGAAAGTGTTACAGTAGTACCGGGTAATGGCTTCGGTTCTCCTGATCATATAAGAATGACTT
TTGCCATGCCGATTGAAGAGATATCCCTAGGTTTGGACAGGATTGAGGAATTTATTACAAAATTCAAACTTGCAGCTTAA

Upstream 100 bases:

>100_bases
TCATATTATACATTATCGAAAGCAGGGTTACTAGAACTACTTTAATATGGTACAATATCAGTTATTATATATACTATTAG
ATTTAGGAGGTAATAAAAAT

Downstream 100 bases:

>100_bases
GGAGAGAAGAGAGAAATAATGGTTATAAGTTTTGAGTATGGTGGGGAAGCTATACAGATTTATATTTTTAAAAGAAACAG
AACTAGTTTAGAGATTCAAG

Product: L-aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MLSDKAKQITPSPTLSINAKAKELKNQGINVISFSQGEPDFNTPDHIKKAAITAIEDNFTRYTPASGMIELKQAISEKFL
RDNDLSYDPNQIIISNGAKHALLNVMTAILNIGDEVLIPTPYWVSYPELVKLVDGCPVPVKASASNNFKVTPEDLKKYLS
SKTRAIIINTPTNPTGQIYSQKELEKIGEFALNNGLYIISDEVYEYMSYNGQQHISIASLSEELKQQTVVLNGVSKSYAM
TGWRIGYSAAPKELAHGMSAIQSHGTSNPSSISQKGALAAIRGPQNCVNEMVAQLDERRKFMYERLSQIPGFQALEPVGS
FYLFASVRELIGKSLDEKIIRDSHDFAELLLDKESVTVVPGNGFGSPDHIRMTFAMPIEEISLGLDRIEEFITKFKLAA

Sequences:

>Translated_399_residues
MLSDKAKQITPSPTLSINAKAKELKNQGINVISFSQGEPDFNTPDHIKKAAITAIEDNFTRYTPASGMIELKQAISEKFL
RDNDLSYDPNQIIISNGAKHALLNVMTAILNIGDEVLIPTPYWVSYPELVKLVDGCPVPVKASASNNFKVTPEDLKKYLS
SKTRAIIINTPTNPTGQIYSQKELEKIGEFALNNGLYIISDEVYEYMSYNGQQHISIASLSEELKQQTVVLNGVSKSYAM
TGWRIGYSAAPKELAHGMSAIQSHGTSNPSSISQKGALAAIRGPQNCVNEMVAQLDERRKFMYERLSQIPGFQALEPVGS
FYLFASVRELIGKSLDEKIIRDSHDFAELLLDKESVTVVPGNGFGSPDHIRMTFAMPIEEISLGLDRIEEFITKFKLAA
>Mature_399_residues
MLSDKAKQITPSPTLSINAKAKELKNQGINVISFSQGEPDFNTPDHIKKAAITAIEDNFTRYTPASGMIELKQAISEKFL
RDNDLSYDPNQIIISNGAKHALLNVMTAILNIGDEVLIPTPYWVSYPELVKLVDGCPVPVKASASNNFKVTPEDLKKYLS
SKTRAIIINTPTNPTGQIYSQKELEKIGEFALNNGLYIISDEVYEYMSYNGQQHISIASLSEELKQQTVVLNGVSKSYAM
TGWRIGYSAAPKELAHGMSAIQSHGTSNPSSISQKGALAAIRGPQNCVNEMVAQLDERRKFMYERLSQIPGFQALEPVGS
FYLFASVRELIGKSLDEKIIRDSHDFAELLLDKESVTVVPGNGFGSPDHIRMTFAMPIEEISLGLDRIEEFITKFKLAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=356, Percent_Identity=27.247191011236, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI56713254, Length=356, Percent_Identity=27.247191011236, Blast_Score=158, Evalue=9e-39,
Organism=Homo sapiens, GI95147551, Length=363, Percent_Identity=25.6198347107438, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI169881279, Length=363, Percent_Identity=25.6198347107438, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI4507369, Length=413, Percent_Identity=24.2130750605327, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI169881281, Length=274, Percent_Identity=24.8175182481752, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI215599424, Length=399, Percent_Identity=21.5538847117794, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI19263340, Length=399, Percent_Identity=21.5538847117794, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4885351, Length=401, Percent_Identity=24.1895261845387, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI187936925, Length=374, Percent_Identity=22.4598930481283, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI14211921, Length=374, Percent_Identity=22.4598930481283, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI149944424, Length=259, Percent_Identity=24.3243243243243, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788627, Length=391, Percent_Identity=27.8772378516624, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1788722, Length=392, Percent_Identity=29.8469387755102, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=24.4155844155844, Blast_Score=136, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=25.5936675461741, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=365, Percent_Identity=26.8493150684932, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71994472, Length=365, Percent_Identity=26.8493150684932, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17567369, Length=363, Percent_Identity=25.8953168044077, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71981209, Length=376, Percent_Identity=25.2659574468085, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=203, Percent_Identity=26.1083743842365, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=370, Percent_Identity=25.4054054054054, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=395, Percent_Identity=24.5569620253165, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=23.943661971831, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573069, Length=394, Percent_Identity=27.9187817258883, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24646114, Length=394, Percent_Identity=27.9187817258883, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI28573067, Length=394, Percent_Identity=27.9187817258883, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI28573065, Length=394, Percent_Identity=27.9187817258883, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=24.1379310344828, Blast_Score=123, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44069; Mature: 44069

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDKAKQITPSPTLSINAKAKELKNQGINVISFSQGEPDFNTPDHIKKAAITAIEDNFT
CCCCCCCCCCCCCCEEECCHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
RYTPASGMIELKQAISEKFLRDNDLSYDPNQIIISNGAKHALLNVMTAILNIGDEVLIPT
EECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEECC
PYWVSYPELVKLVDGCPVPVKASASNNFKVTPEDLKKYLSSKTRAIIINTPTNPTGQIYS
CCCCCHHHHHHHHCCCCCCEECCCCCCCEECHHHHHHHHCCCCCEEEEECCCCCCCCCCC
QKELEKIGEFALNNGLYIISDEVYEYMSYNGQQHISIASLSEELKQQTVVLNGVSKSYAM
HHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHEECCCHHHHC
TGWRIGYSAAPKELAHGMSAIQSHGTSNPSSISQKGALAAIRGPQNCVNEMVAQLDERRK
CCEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
FMYERLSQIPGFQALEPVGSFYLFASVRELIGKSLDEKIIRDSHDFAELLLDKESVTVVP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEE
GNGFGSPDHIRMTFAMPIEEISLGLDRIEEFITKFKLAA
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSDKAKQITPSPTLSINAKAKELKNQGINVISFSQGEPDFNTPDHIKKAAITAIEDNFT
CCCCCCCCCCCCCCEEECCHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
RYTPASGMIELKQAISEKFLRDNDLSYDPNQIIISNGAKHALLNVMTAILNIGDEVLIPT
EECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEECC
PYWVSYPELVKLVDGCPVPVKASASNNFKVTPEDLKKYLSSKTRAIIINTPTNPTGQIYS
CCCCCHHHHHHHHCCCCCCEECCCCCCCEECHHHHHHHHCCCCCEEEEECCCCCCCCCCC
QKELEKIGEFALNNGLYIISDEVYEYMSYNGQQHISIASLSEELKQQTVVLNGVSKSYAM
HHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHEECCCHHHHC
TGWRIGYSAAPKELAHGMSAIQSHGTSNPSSISQKGALAAIRGPQNCVNEMVAQLDERRK
CCEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHH
FMYERLSQIPGFQALEPVGSFYLFASVRELIGKSLDEKIIRDSHDFAELLLDKESVTVVP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEE
GNGFGSPDHIRMTFAMPIEEISLGLDRIEEFITKFKLAA
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1990006; 2155199 [H]