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The map label for this gene is infC [H]

Identifier: 188586438

GI number: 188586438

Start: 1896201

End: 1896662

Strand: Reverse

Name: infC [H]

Synonym: Nther_1823

Alternate gene names: 188586438

Gene position: 1896662-1896201 (Counterclockwise)

Preceding gene: 188586439

Following gene: 188586437

Centisome position: 59.92

GC content: 36.15

Gene sequence:

>462_bases
GTGGTTGGTAAGGATGGAAAACAATTAGGTGTCATGTCCCCTAAGGAAGCTTTGAAAATCGCTGAAGAAAACAATTTAGA
CCTGGTCACAGTGGCTCCTAAAGCCAAGCCACCAGTATGCCGAATCATGGATTACGGTAAATTCAAGTATGAGCAAAATA
AGAAGGAAAAGCAAGCCAAGAAAAAACAAAAGACAATTAATGTCAAAGAAGTTAAGTTAAGACCTAATATTGAGGAACAC
GACTTTAATACTAAACTTAATAATGCTAGGAAGTTTTTAAAAAAGGAAGATAAAGTAAAAGTGACAATTATGTTTAGGGG
CAGGGAGATTACCCACCCAGAAAATGGTAAAGAGTTGTGTCAGAAAATGGCAAAAGAAGTAGAAGACATAGCTGTAATTG
AAAAAAAGCCCAGTGTAGAAGGTAAAAATATGATTATGGTTCTTGCACCAAGGCAAGAGTAA

Upstream 100 bases:

>100_bases
TTTTGAATAATTATCGAACTGTTTTAAAATTCCCAGGAGGTGAACAGATATTAGCAAAGAGCTACCTGTTAATGAGCAAA
TTAAGGCTCGTGAAATTCGA

Downstream 100 bases:

>100_bases
TTAAACAGAAATTAGCTAACTGAAGGGAGGACTATTGCAATGCCTAAAATGAAAACTCATAAAGGTGCAGCTAAACGGTT
CAAGAAAACTGGTAAAGGTA

Product: translation initiation factor 3 (bIF-3)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MVGKDGKQLGVMSPKEALKIAEENNLDLVTVAPKAKPPVCRIMDYGKFKYEQNKKEKQAKKKQKTINVKEVKLRPNIEEH
DFNTKLNNARKFLKKEDKVKVTIMFRGREITHPENGKELCQKMAKEVEDIAVIEKKPSVEGKNMIMVLAPRQE

Sequences:

>Translated_153_residues
MVGKDGKQLGVMSPKEALKIAEENNLDLVTVAPKAKPPVCRIMDYGKFKYEQNKKEKQAKKKQKTINVKEVKLRPNIEEH
DFNTKLNNARKFLKKEDKVKVTIMFRGREITHPENGKELCQKMAKEVEDIAVIEKKPSVEGKNMIMVLAPRQE
>Mature_153_residues
MVGKDGKQLGVMSPKEALKIAEENNLDLVTVAPKAKPPVCRIMDYGKFKYEQNKKEKQAKKKQKTINVKEVKLRPNIEEH
DFNTKLNNARKFLKKEDKVKVTIMFRGREITHPENGKELCQKMAKEVEDIAVIEKKPSVEGKNMIMVLAPRQE

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=152, Percent_Identity=50, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 17603; Mature: 17603

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGKDGKQLGVMSPKEALKIAEENNLDLVTVAPKAKPPVCRIMDYGKFKYEQNKKEKQAK
CCCCCCCEECCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHH
KKQKTINVKEVKLRPNIEEHDFNTKLNNARKFLKKEDKVKVTIMFRGREITHPENGKELC
HHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHH
QKMAKEVEDIAVIEKKPSVEGKNMIMVLAPRQE
HHHHHHHHHHEEECCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MVGKDGKQLGVMSPKEALKIAEENNLDLVTVAPKAKPPVCRIMDYGKFKYEQNKKEKQAK
CCCCCCCEECCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCCCHHHHHHH
KKQKTINVKEVKLRPNIEEHDFNTKLNNARKFLKKEDKVKVTIMFRGREITHPENGKELC
HHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHH
QKMAKEVEDIAVIEKKPSVEGKNMIMVLAPRQE
HHHHHHHHHHEEECCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]