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The map label for this gene is cisA [H]

Identifier: 188586355

GI number: 188586355

Start: 1803334

End: 1804851

Strand: Reverse

Name: cisA [H]

Synonym: Nther_1738

Alternate gene names: 188586355

Gene position: 1804851-1803334 (Counterclockwise)

Preceding gene: 188586357

Following gene: 188586354

Centisome position: 57.02

GC content: 32.54

Gene sequence:

>1518_bases
ATGATCGGGATATATGCTCGAGTCAGCACAGAGGAACAAGCAAAAACAGGGACTAGTATTCAAGATCAGTTAAGAGCCTG
TAAGGAGTATTTATCCAAGGATGAGCTTCAAAATTATCAACTTCAGGAATATATTGATGAAGGAATTTCGGGTGAAATCT
TTGAACGTCCTGCTCTATCTAAATTGAGAAATGATTCCGAAAGGGGGAACTTAACAGCAGTTATCTGTTTTGACCCTGAT
CGATTATCTCGTAAATTAATGCATCAACTAATAATTACTGAAGAACTTAATGAACATGGAGTGGAGCTATTATTCGTTAA
TGGCTATTATCAAAAAACCCCAGAAGGGAATTTGTTTTATAGTTTAAGAGGAGCAATTTCAGAATTTGAAAAGGCTAAAA
TTACTGAACGTATGAAACGAGGAAGATTAGAAAAAGCCAGACAAGGTTCAGTTTTAAGAGATTATAATGTATATGGCTAT
AATTATAATAAAAATAATCGTAGTTTGGAGATAAATAAAAAAGAGAGTGAGATAGTTAAGTTAATATTTGATTTATTTAC
AAGGCCTGAGGGTCAAAATTTAGGGATCAATGGTATTGCAAATTATTTGACGAAAAAAGGGATTCCGACTAAAACAAACA
AGCAAACTTGGCATAGACAAGTAGTAAAACAAATCCTGCAAAACCCAGTTTATATTGGTAGTTTTTACCAAAACAAATGG
AAAGCGGAAGCTACAAGGGACTCACCAGTACAAAAAGCAACTAAGTCGATAAGCCCTAAGGTAAGGGATCAAAGTGATTG
GATTGAAATTAAATGTCCAGCTATAATTACAGAGAGCAAATTCTATAAAGCCCAAGAACTTCTGAAACAGTCCAGGAGAA
AGTGGGTTAAGCAAGGAAAACGTCTTTATCTGTTAAGTGGTTTAGTGAAATGCGGTTTATGTAATAATACTATGACTGGC
AGACGTGTTAAGAATTGGGGTGAGTATGTATTTATTTATACTGATAAAAAGAATAATCCCGGAATCTATCAGGGCTGTGG
TTTGAATATTCCGTGTAGTGAGTTAGACAAAGTTGTTTCAGAAGTGGTGTTTAACTGGTTAACAGATTTAAATGAAATAA
AATCTCAAGTATCCGAGGTTTTAGAAGGGCAAAATAAACATATTGAACTAGATATAAGTGAAACTGAGTCAAAACTTTCT
AAAACAAAGCAACAAAAGAAAAAGCTCCTTGATTTAATTGGTGAAGATACCATATCAATTCAAGAAGCAAGGGAGTATTT
GCAAAGCTGCAATCAGAAAGAGAAGAAATTGAGTCAAAAATTAAAGGAATTACAAGCTCATAAGAAGAATATAAAAAAAC
AGTATCAATCTAAACAAAGTAAGCATATAATTTCATCGACTTTTGCAAAGATTAAAAATTACAATGAAGAAGATTTAATT
AATCAACAGCAAATCATTAGAACCATGATTAGAGAAATCATAATCTATAAAAATAGTATAGTCATTAATACCCATTAA

Upstream 100 bases:

>100_bases
ATCAACAATATAACTATTAACAAAGGCGAATATTTTGATGAACAAAAACAAAAATGCATTAATTTTTTAATAAAAAAAGC
TAGTGAGGAGGAAAAAAGCA

Downstream 100 bases:

>100_bases
ACTGGATTAAGTGGAACTGGTTAGCTGGGACTTGCTAAACTCTTGTCATTGAAACGGAGATTTTAATGCATTTTAGAGCA
ACTAAAAAGAACCGCTCAGA

Product: Resolvase domain

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MIGIYARVSTEEQAKTGTSIQDQLRACKEYLSKDELQNYQLQEYIDEGISGEIFERPALSKLRNDSERGNLTAVICFDPD
RLSRKLMHQLIITEELNEHGVELLFVNGYYQKTPEGNLFYSLRGAISEFEKAKITERMKRGRLEKARQGSVLRDYNVYGY
NYNKNNRSLEINKKESEIVKLIFDLFTRPEGQNLGINGIANYLTKKGIPTKTNKQTWHRQVVKQILQNPVYIGSFYQNKW
KAEATRDSPVQKATKSISPKVRDQSDWIEIKCPAIITESKFYKAQELLKQSRRKWVKQGKRLYLLSGLVKCGLCNNTMTG
RRVKNWGEYVFIYTDKKNNPGIYQGCGLNIPCSELDKVVSEVVFNWLTDLNEIKSQVSEVLEGQNKHIELDISETESKLS
KTKQQKKKLLDLIGEDTISIQEAREYLQSCNQKEKKLSQKLKELQAHKKNIKKQYQSKQSKHIISSTFAKIKNYNEEDLI
NQQQIIRTMIREIIIYKNSIVINTH

Sequences:

>Translated_505_residues
MIGIYARVSTEEQAKTGTSIQDQLRACKEYLSKDELQNYQLQEYIDEGISGEIFERPALSKLRNDSERGNLTAVICFDPD
RLSRKLMHQLIITEELNEHGVELLFVNGYYQKTPEGNLFYSLRGAISEFEKAKITERMKRGRLEKARQGSVLRDYNVYGY
NYNKNNRSLEINKKESEIVKLIFDLFTRPEGQNLGINGIANYLTKKGIPTKTNKQTWHRQVVKQILQNPVYIGSFYQNKW
KAEATRDSPVQKATKSISPKVRDQSDWIEIKCPAIITESKFYKAQELLKQSRRKWVKQGKRLYLLSGLVKCGLCNNTMTG
RRVKNWGEYVFIYTDKKNNPGIYQGCGLNIPCSELDKVVSEVVFNWLTDLNEIKSQVSEVLEGQNKHIELDISETESKLS
KTKQQKKKLLDLIGEDTISIQEAREYLQSCNQKEKKLSQKLKELQAHKKNIKKQYQSKQSKHIISSTFAKIKNYNEEDLI
NQQQIIRTMIREIIIYKNSIVINTH
>Mature_505_residues
MIGIYARVSTEEQAKTGTSIQDQLRACKEYLSKDELQNYQLQEYIDEGISGEIFERPALSKLRNDSERGNLTAVICFDPD
RLSRKLMHQLIITEELNEHGVELLFVNGYYQKTPEGNLFYSLRGAISEFEKAKITERMKRGRLEKARQGSVLRDYNVYGY
NYNKNNRSLEINKKESEIVKLIFDLFTRPEGQNLGINGIANYLTKKGIPTKTNKQTWHRQVVKQILQNPVYIGSFYQNKW
KAEATRDSPVQKATKSISPKVRDQSDWIEIKCPAIITESKFYKAQELLKQSRRKWVKQGKRLYLLSGLVKCGLCNNTMTG
RRVKNWGEYVFIYTDKKNNPGIYQGCGLNIPCSELDKVVSEVVFNWLTDLNEIKSQVSEVLEGQNKHIELDISETESKLS
KTKQQKKKLLDLIGEDTISIQEAREYLQSCNQKEKKLSQKLKELQAHKKNIKKQYQSKQSKHIISSTFAKIKNYNEEDLI
NQQQIIRTMIREIIIYKNSIVINTH

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787404, Length=153, Percent_Identity=32.0261437908497, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 58677; Mature: 58677

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00397 RECOMBINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGIYARVSTEEQAKTGTSIQDQLRACKEYLSKDELQNYQLQEYIDEGISGEIFERPALS
CEEEEEECCCHHHHHCCCCHHHHHHHHHHHHCHHHHHCCHHHHHHCCCCCCCHHCCHHHH
KLRNDSERGNLTAVICFDPDRLSRKLMHQLIITEELNEHGVELLFVNGYYQKTPEGNLFY
HHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEECCCCCCCEEE
SLRGAISEFEKAKITERMKRGRLEKARQGSVLRDYNVYGYNYNKNNRSLEINKKESEIVK
HHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEECEEEEEEECCCCCEEEECCHHHHHHH
LIFDLFTRPEGQNLGINGIANYLTKKGIPTKTNKQTWHRQVVKQILQNPVYIGSFYQNKW
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHCCH
KAEATRDSPVQKATKSISPKVRDQSDWIEIKCPAIITESKFYKAQELLKQSRRKWVKQGK
HCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCEEEECHHHHHHHHHHHHHHHHHHHCCC
RLYLLSGLVKCGLCNNTMTGRRVKNWGEYVFIYTDKKNNPGIYQGCGLNIPCSELDKVVS
EEEEHHHHHHHCCCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
EVVFNWLTDLNEIKSQVSEVLEGQNKHIELDISETESKLSKTKQQKKKLLDLIGEDTISI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCH
QEAREYLQSCNQKEKKLSQKLKELQAHKKNIKKQYQSKQSKHIISSTFAKIKNYNEEDLI
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
NQQQIIRTMIREIIIYKNSIVINTH
CHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MIGIYARVSTEEQAKTGTSIQDQLRACKEYLSKDELQNYQLQEYIDEGISGEIFERPALS
CEEEEEECCCHHHHHCCCCHHHHHHHHHHHHCHHHHHCCHHHHHHCCCCCCCHHCCHHHH
KLRNDSERGNLTAVICFDPDRLSRKLMHQLIITEELNEHGVELLFVNGYYQKTPEGNLFY
HHCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEEEECEECCCCCCCEEE
SLRGAISEFEKAKITERMKRGRLEKARQGSVLRDYNVYGYNYNKNNRSLEINKKESEIVK
HHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCEEECEEEEEEECCCCCEEEECCHHHHHHH
LIFDLFTRPEGQNLGINGIANYLTKKGIPTKTNKQTWHRQVVKQILQNPVYIGSFYQNKW
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHCCH
KAEATRDSPVQKATKSISPKVRDQSDWIEIKCPAIITESKFYKAQELLKQSRRKWVKQGK
HCCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCEEEECHHHHHHHHHHHHHHHHHHHCCC
RLYLLSGLVKCGLCNNTMTGRRVKNWGEYVFIYTDKKNNPGIYQGCGLNIPCSELDKVVS
EEEEHHHHHHHCCCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
EVVFNWLTDLNEIKSQVSEVLEGQNKHIELDISETESKLSKTKQQKKKLLDLIGEDTISI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCH
QEAREYLQSCNQKEKKLSQKLKELQAHKKNIKKQYQSKQSKHIISSTFAKIKNYNEEDLI
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
NQQQIIRTMIREIIIYKNSIVINTH
CHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]