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The map label for this gene is aroK [H]

Identifier: 188586338

GI number: 188586338

Start: 1790296

End: 1790865

Strand: Reverse

Name: aroK [H]

Synonym: Nther_1721

Alternate gene names: 188586338

Gene position: 1790865-1790296 (Counterclockwise)

Preceding gene: 188586339

Following gene: 188586337

Centisome position: 56.57

GC content: 28.6

Gene sequence:

>570_bases
ATGGCCAGATTAAATTTAAATCAATTAAAAATACATGTAGTATTATTGGGTTTTATGGGAACAGGAAAAACACATAGTGG
TCAAATACTGTCAAATATGATGAACGTACCTTGTTATGATACTGATAAAATAATTGTCAGTCGTACAGGTATGAATATCA
ACGATATTTTCAAACATTATGGAGAAAATTATTTTAGAGACCAGGAAACAGATATTCTAACAAAACTGGTAAATGAGAAA
TCTCCATGTATAATTACTACAGGTGGAGGGATTGTAATTAGAGAACATAACTGGTATGTAATGGATAAGAATTCAGTAAC
TTTTTCGTTGTTAGCTAGTCCAAAAACTATATATGATAGATTAAAGTATGATGAGACTAGACCTTTACTCAATACAAATG
ATAAATTTTTAAAAATAAAACAATTATTAATTAACAGATTGGAATACTATGAGAAGGGAGACCATTTAATATGGACTGAT
AAGTTAACTCCTCAAGAAGTTGCTAATCAAATTTACAGTAAATTATACTCTAATGGCTATATGTATAGGAGTGATTTAAA
TGGTTGCTAA

Upstream 100 bases:

>100_bases
TTTGTACAATTTTCTACAGATGTGACTACTGCTATAATTAAAGCGATTGATCAAGTTAAAACTCAGCCTAGACATTAAAA
TTTTTTGTGAGGGGTAAGTA

Downstream 100 bases:

>100_bases
TAATATCATTAACTCAATTGGGGATACTCCCATGGTTGCACTTGCCGGTAACGATGGAGCCCAAATTTATGCTAAGTTAG
AATACTTTAATCCAGGGGGA

Product: Shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MARLNLNQLKIHVVLLGFMGTGKTHSGQILSNMMNVPCYDTDKIIVSRTGMNINDIFKHYGENYFRDQETDILTKLVNEK
SPCIITTGGGIVIREHNWYVMDKNSVTFSLLASPKTIYDRLKYDETRPLLNTNDKFLKIKQLLINRLEYYEKGDHLIWTD
KLTPQEVANQIYSKLYSNGYMYRSDLNGC

Sequences:

>Translated_189_residues
MARLNLNQLKIHVVLLGFMGTGKTHSGQILSNMMNVPCYDTDKIIVSRTGMNINDIFKHYGENYFRDQETDILTKLVNEK
SPCIITTGGGIVIREHNWYVMDKNSVTFSLLASPKTIYDRLKYDETRPLLNTNDKFLKIKQLLINRLEYYEKGDHLIWTD
KLTPQEVANQIYSKLYSNGYMYRSDLNGC
>Mature_188_residues
ARLNLNQLKIHVVLLGFMGTGKTHSGQILSNMMNVPCYDTDKIIVSRTGMNINDIFKHYGENYFRDQETDILTKLVNEKS
PCIITTGGGIVIREHNWYVMDKNSVTFSLLASPKTIYDRLKYDETRPLLNTNDKFLKIKQLLINRLEYYEKGDHLIWTDK
LTPQEVANQIYSKLYSNGYMYRSDLNGC

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=171, Percent_Identity=32.7485380116959, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786587, Length=164, Percent_Identity=28.6585365853659, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 21928; Mature: 21796

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLNLNQLKIHVVLLGFMGTGKTHSGQILSNMMNVPCYDTDKIIVSRTGMNINDIFKHY
CCCCCHHHEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHH
GENYFRDQETDILTKLVNEKSPCIITTGGGIVIREHNWYVMDKNSVTFSLLASPKTIYDR
CCHHCCCCHHHHHHHHHCCCCCEEEEECCEEEEEECCEEEEECCCEEEEEECCCHHHHHH
LKYDETRPLLNTNDKFLKIKQLLINRLEYYEKGDHLIWTDKLTPQEVANQIYSKLYSNGY
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCE
MYRSDLNGC
EEECCCCCC
>Mature Secondary Structure 
ARLNLNQLKIHVVLLGFMGTGKTHSGQILSNMMNVPCYDTDKIIVSRTGMNINDIFKHY
CCCCHHHEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHH
GENYFRDQETDILTKLVNEKSPCIITTGGGIVIREHNWYVMDKNSVTFSLLASPKTIYDR
CCHHCCCCHHHHHHHHHCCCCCEEEEECCEEEEEECCEEEEECCCEEEEEECCCHHHHHH
LKYDETRPLLNTNDKFLKIKQLLINRLEYYEKGDHLIWTDKLTPQEVANQIYSKLYSNGY
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCE
MYRSDLNGC
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA