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The map label for this gene is xerD [H]

Identifier: 188586285

GI number: 188586285

Start: 1744767

End: 1745654

Strand: Reverse

Name: xerD [H]

Synonym: Nther_1668

Alternate gene names: 188586285

Gene position: 1745654-1744767 (Counterclockwise)

Preceding gene: 188586286

Following gene: 188586284

Centisome position: 55.15

GC content: 34.46

Gene sequence:

>888_bases
ATGGAAAAAACCGTTCACGAATTTATCTATTATTTAAATGTTGAACGAGGTTTGTCAGAGAACACGCTAAACTCGTATTT
GCGCGATCTAAAAAACTTTTTAGAGTTCCTTAACCAACAAGGTGTAACAAAGTGGCAGGAAGTCAAACGTACTCATATTA
TGAAATATTTAATATTTATGAAAGAAAAGGGTAAAGCTTCGGCCACCGTAACTAGAAACATAGCCTCTGTCCGGTCTTTC
TTTCAGTTTTTACTTCAGGAAGGCATGATTTCAGAGAATCCATCAACTGATTTAGAAACTCCCAAACAAGAAAAAAAATT
GCCTGAAATTTTATCACCACAGGAAGTGGACAAACTTTTAAACCAACCGGATACTACCGATTTCAAAGGTAAAAGAGATA
AGGCAATGCTTGAGGTTTTGTATGCAACAGGCATGAGAGTTAGTGAATTAATATCATTGAATGTTGAGCATGTTGATAGT
AACAATGGGTACATACTATGTAAAGGGAAAGGCGATAAGGAAAGAATTGTTCCTCTAGGTAAAATGGCAATAAAAAGTGT
TTCTGATTACATATCAAAAAGCCGACCCCAGTTAAGAAAGAACTTATCTGAACCAGCGTTATTTTTAAATCATCATGGGA
AAAGATTATCTCGACAAGGCTTTTGGAAAATATTAAAAAAATATGCTGAAAAAATTGGGATTAAACAAAAAATCACACCT
CATACACTTAGACATTCATTTGCCACACATTTACTTGAAAATGGAGCTGATTTAAGAGCAGTTCAAGAAATGTTGGGACA
TTCAGATATTTCTACTACACAGATATATACTCACTTAACAAAACAACGCCTAAAGGACGTTTATTCAAAATCTCATCCCA
GGGCTTAA

Upstream 100 bases:

>100_bases
AATTAGTTCAATCGAAGAGTTCAACTATCAACAACGGAGTATAACAGAGCCTAAAGACTAAATAGTAATATTTAATGATT
TTAAGAAGGAGTTATTGCCT

Downstream 100 bases:

>100_bases
AGCCTGGAGAAGGAGGTATTTACTAGTGCAAGTAAACAGAGTTATTGTCCTTGTTCTTGACAGTCTGGGAATTGGCGCTT
TACCAGATGCATCTAAATAT

Product: tyrosine recombinase XerD subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MEKTVHEFIYYLNVERGLSENTLNSYLRDLKNFLEFLNQQGVTKWQEVKRTHIMKYLIFMKEKGKASATVTRNIASVRSF
FQFLLQEGMISENPSTDLETPKQEKKLPEILSPQEVDKLLNQPDTTDFKGKRDKAMLEVLYATGMRVSELISLNVEHVDS
NNGYILCKGKGDKERIVPLGKMAIKSVSDYISKSRPQLRKNLSEPALFLNHHGKRLSRQGFWKILKKYAEKIGIKQKITP
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQIYTHLTKQRLKDVYSKSHPRA

Sequences:

>Translated_295_residues
MEKTVHEFIYYLNVERGLSENTLNSYLRDLKNFLEFLNQQGVTKWQEVKRTHIMKYLIFMKEKGKASATVTRNIASVRSF
FQFLLQEGMISENPSTDLETPKQEKKLPEILSPQEVDKLLNQPDTTDFKGKRDKAMLEVLYATGMRVSELISLNVEHVDS
NNGYILCKGKGDKERIVPLGKMAIKSVSDYISKSRPQLRKNLSEPALFLNHHGKRLSRQGFWKILKKYAEKIGIKQKITP
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQIYTHLTKQRLKDVYSKSHPRA
>Mature_295_residues
MEKTVHEFIYYLNVERGLSENTLNSYLRDLKNFLEFLNQQGVTKWQEVKRTHIMKYLIFMKEKGKASATVTRNIASVRSF
FQFLLQEGMISENPSTDLETPKQEKKLPEILSPQEVDKLLNQPDTTDFKGKRDKAMLEVLYATGMRVSELISLNVEHVDS
NNGYILCKGKGDKERIVPLGKMAIKSVSDYISKSRPQLRKNLSEPALFLNHHGKRLSRQGFWKILKKYAEKIGIKQKITP
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQIYTHLTKQRLKDVYSKSHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=42.8082191780822, Blast_Score=243, Evalue=9e-66,
Organism=Escherichia coli, GI1790244, Length=297, Percent_Identity=38.047138047138, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1790768, Length=182, Percent_Identity=29.1208791208791, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790767, Length=196, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34061; Mature: 34061

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTVHEFIYYLNVERGLSENTLNSYLRDLKNFLEFLNQQGVTKWQEVKRTHIMKYLIFM
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KEKGKASATVTRNIASVRSFFQFLLQEGMISENPSTDLETPKQEKKLPEILSPQEVDKLL
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHCCHHHHHHHH
NQPDTTDFKGKRDKAMLEVLYATGMRVSELISLNVEHVDSNNGYILCKGKGDKERIVPLG
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHH
KMAIKSVSDYISKSRPQLRKNLSEPALFLNHHGKRLSRQGFWKILKKYAEKIGIKQKITP
HHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQIYTHLTKQRLKDVYSKSHPRA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEKTVHEFIYYLNVERGLSENTLNSYLRDLKNFLEFLNQQGVTKWQEVKRTHIMKYLIFM
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KEKGKASATVTRNIASVRSFFQFLLQEGMISENPSTDLETPKQEKKLPEILSPQEVDKLL
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHCCHHHHHHHH
NQPDTTDFKGKRDKAMLEVLYATGMRVSELISLNVEHVDSNNGYILCKGKGDKERIVPLG
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCEEEEECCCCHHHHHHHH
KMAIKSVSDYISKSRPQLRKNLSEPALFLNHHGKRLSRQGFWKILKKYAEKIGIKQKITP
HHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
HTLRHSFATHLLENGADLRAVQEMLGHSDISTTQIYTHLTKQRLKDVYSKSHPRA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10537218; 10498718 [H]