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The map label for this gene is mutL [H]

Identifier: 188585797

GI number: 188585797

Start: 1240339

End: 1241709

Strand: Direct

Name: mutL [H]

Synonym: Nther_1171

Alternate gene names: 188585797

Gene position: 1240339-1241709 (Clockwise)

Preceding gene: 188585796

Following gene: 188585798

Centisome position: 39.18

GC content: 40.92

Gene sequence:

>1371_bases
ATGGGACAGGAAAAACTAGTAGCAGAAGTCGGCAGTACTACTACAGTTGTTTCAATGTATAATGAGAAGGGAAAGCTAGT
AGCGCAAGGACAAAGTTCTACTACTGTTGAAGCAGGAGATGTCCTCCTGGGCTTGAATCGAGCCCAGGAGGATTTAAAAC
AACAACTGGACCAAAATGGAAGCTTCTCTGGATCTTTAGATGATTTAGAAATGTATGCTACTAGCAGTGCCGCTGGTGGT
TTAAAGATGACAGTTCACGGTCTGGTTTACGATATGACAGCCCGTGCTTCTAGAGAAGCTGCATTAGGGGCAGGTGCCGT
TATTCACCAAGTTACCGCCGGTGAATTATCCCAAGAAGATATAGATAACACTTTGGAGATTTCACCAAATATTATTTTAC
TGGCCGGTGGGGTGGACTACGGAGAAGAAAAAACTGTGGTAAATAATGCCCGTTATATAGCAGACAGTGGCATAAAAGCT
CCTATAGTTTATGCTGGTAATGTAGCTTGTCAGGAAAAAGTGGTTAAAATTTTAGAATCTGCAGGCCTTTATGTGAAAGC
TGTTGAAAACGTTTATCCTACCGTTGACGAGTTAAACGTGGAACCAGCCCGGAAAGCAATACAACAAATTTTCCAAAGCC
ATATTGTGCATGCTCCTGGAATGGAAAAAATTAAAGAAAGAGTTAATGGAAGTATTATGCCAACTCCAGGAGCTGTAATG
GAAGGAGCCAAACGGGTAGCTGATAAAATAGGTGATGCTATGGTTATTGACGTAGGTGGTGCTACTACCGATGTCCACTC
AGTTACAGATGGTTCGCAAGAAATGCTCGACTTGACTGTGGCACCTGAACCCAGGGCTAAAAGAACGGTAGAAGGTGACT
TGGGTGTTTATAGAAATGCTAAGAATTTGATTGATTTAATGGACGAATCATATTTTGAGTCGGGGATGAGCCAAGAAGAT
ATGTTAAATATCATTGCCGACTGGGAACCTTTTCCACAGAATGAATCGGAAAAACATCTATTACAATTGTTTGCAAAAAT
AGCTACCTTCACAGCAGTAGATAGACATGCCGGAGCTATAAAATATCTCTATGGGCCCACAGGACGTCAAAAGATAGTTA
AAGGGAAAGATTTAACTAAAATTAGATATGTGATTGGCACTGGAGGAGCCTTAGGTAGGAGTAAACCTGGAGAAAAGGTT
ATAAAAGAGTTATTAAAACGTTATCAACCAAGCAAATTAACACCTCCAAAAGATGCGCAATTAATACTGGATAGTAACTA
TAGCTTGGCAGCTATCGGTTTGCTTTCAGTTCAAGCACCAGAAATGGCGGATAGAATCATAGAGAATTTTGCCGAACATA
AGGCCTTGTAA

Upstream 100 bases:

>100_bases
GGAAGAGGTACAAAAGGAATTAATGTGGCAAGCTATCTTGTAAAACAAATGAAAGAAGATGCTGACTCCAATTAGTGGCT
CTAATTAAGGAGGTATTGCG

Downstream 100 bases:

>100_bases
AGATTTGAGTAATATTTTAAAATATTGTTTGTGTAAATTTTTTCTGTAACAAGTTATAATACTTGTTACAGAATTTTTTT
TAGGGAGAGATTTATATGAC

Product: putative component of D-ornithine aminomutase

Products: L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MGQEKLVAEVGSTTTVVSMYNEKGKLVAQGQSSTTVEAGDVLLGLNRAQEDLKQQLDQNGSFSGSLDDLEMYATSSAAGG
LKMTVHGLVYDMTARASREAALGAGAVIHQVTAGELSQEDIDNTLEISPNIILLAGGVDYGEEKTVVNNARYIADSGIKA
PIVYAGNVACQEKVVKILESAGLYVKAVENVYPTVDELNVEPARKAIQQIFQSHIVHAPGMEKIKERVNGSIMPTPGAVM
EGAKRVADKIGDAMVIDVGGATTDVHSVTDGSQEMLDLTVAPEPRAKRTVEGDLGVYRNAKNLIDLMDESYFESGMSQED
MLNIIADWEPFPQNESEKHLLQLFAKIATFTAVDRHAGAIKYLYGPTGRQKIVKGKDLTKIRYVIGTGGALGRSKPGEKV
IKELLKRYQPSKLTPPKDAQLILDSNYSLAAIGLLSVQAPEMADRIIENFAEHKAL

Sequences:

>Translated_456_residues
MGQEKLVAEVGSTTTVVSMYNEKGKLVAQGQSSTTVEAGDVLLGLNRAQEDLKQQLDQNGSFSGSLDDLEMYATSSAAGG
LKMTVHGLVYDMTARASREAALGAGAVIHQVTAGELSQEDIDNTLEISPNIILLAGGVDYGEEKTVVNNARYIADSGIKA
PIVYAGNVACQEKVVKILESAGLYVKAVENVYPTVDELNVEPARKAIQQIFQSHIVHAPGMEKIKERVNGSIMPTPGAVM
EGAKRVADKIGDAMVIDVGGATTDVHSVTDGSQEMLDLTVAPEPRAKRTVEGDLGVYRNAKNLIDLMDESYFESGMSQED
MLNIIADWEPFPQNESEKHLLQLFAKIATFTAVDRHAGAIKYLYGPTGRQKIVKGKDLTKIRYVIGTGGALGRSKPGEKV
IKELLKRYQPSKLTPPKDAQLILDSNYSLAAIGLLSVQAPEMADRIIENFAEHKAL
>Mature_455_residues
GQEKLVAEVGSTTTVVSMYNEKGKLVAQGQSSTTVEAGDVLLGLNRAQEDLKQQLDQNGSFSGSLDDLEMYATSSAAGGL
KMTVHGLVYDMTARASREAALGAGAVIHQVTAGELSQEDIDNTLEISPNIILLAGGVDYGEEKTVVNNARYIADSGIKAP
IVYAGNVACQEKVVKILESAGLYVKAVENVYPTVDELNVEPARKAIQQIFQSHIVHAPGMEKIKERVNGSIMPTPGAVME
GAKRVADKIGDAMVIDVGGATTDVHSVTDGSQEMLDLTVAPEPRAKRTVEGDLGVYRNAKNLIDLMDESYFESGMSQEDM
LNIIADWEPFPQNESEKHLLQLFAKIATFTAVDRHAGAIKYLYGPTGRQKIVKGKDLTKIRYVIGTGGALGRSKPGEKVI
KELLKRYQPSKLTPPKDAQLILDSNYSLAAIGLLSVQAPEMADRIIENFAEHKAL

Specific function: May play a role in glutamate fermentation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006230
- InterPro:   IPR002821 [H]

Pfam domain/function: PF01968 Hydantoinase_A [H]

EC number: 5.4.99.1

Molecular weight: Translated: 49103; Mature: 48971

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQEKLVAEVGSTTTVVSMYNEKGKLVAQGQSSTTVEAGDVLLGLNRAQEDLKQQLDQNG
CCCHHHHHHCCCCEEEEEEECCCCCEEECCCCCCEEECCCEEEECHHHHHHHHHHHHCCC
SFSGSLDDLEMYATSSAAGGLKMTVHGLVYDMTARASREAALGAGAVIHQVTAGELSQED
CCCCCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHH
IDNTLEISPNIILLAGGVDYGEEKTVVNNARYIADSGIKAPIVYAGNVACQEKVVKILES
CCCEEEECCCEEEEECCCCCCCCCEEECCCEEEECCCCCCCEEEECCHHHHHHHHHHHHH
AGLYVKAVENVYPTVDELNVEPARKAIQQIFQSHIVHAPGMEKIKERVNGSIMPTPGAVM
CCCEEEEHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHH
EGAKRVADKIGDAMVIDVGGATTDVHSVTDGSQEMLDLTVAPEPRAKRTVEGDLGVYRNA
HHHHHHHHHHCCEEEEECCCCCCCCHHCCCCCHHHEEEEECCCCCCCCCCCCCCHHHHCH
KNLIDLMDESYFESGMSQEDMLNIIADWEPFPQNESEKHLLQLFAKIATFTAVDRHAGAI
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
KYLYGPTGRQKIVKGKDLTKIRYVIGTGGALGRSKPGEKVIKELLKRYQPSKLTPPKDAQ
EEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCE
LILDSNYSLAAIGLLSVQAPEMADRIIENFAEHKAL
EEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GQEKLVAEVGSTTTVVSMYNEKGKLVAQGQSSTTVEAGDVLLGLNRAQEDLKQQLDQNG
CCHHHHHHCCCCEEEEEEECCCCCEEECCCCCCEEECCCEEEECHHHHHHHHHHHHCCC
SFSGSLDDLEMYATSSAAGGLKMTVHGLVYDMTARASREAALGAGAVIHQVTAGELSQED
CCCCCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHH
IDNTLEISPNIILLAGGVDYGEEKTVVNNARYIADSGIKAPIVYAGNVACQEKVVKILES
CCCEEEECCCEEEEECCCCCCCCCEEECCCEEEECCCCCCCEEEECCHHHHHHHHHHHHH
AGLYVKAVENVYPTVDELNVEPARKAIQQIFQSHIVHAPGMEKIKERVNGSIMPTPGAVM
CCCEEEEHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHH
EGAKRVADKIGDAMVIDVGGATTDVHSVTDGSQEMLDLTVAPEPRAKRTVEGDLGVYRNA
HHHHHHHHHHCCEEEEECCCCCCCCHHCCCCCHHHEEEEECCCCCCCCCCCCCCHHHHCH
KNLIDLMDESYFESGMSQEDMLNIIADWEPFPQNESEKHLLQLFAKIATFTAVDRHAGAI
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
KYLYGPTGRQKIVKGKDLTKIRYVIGTGGALGRSKPGEKVIKELLKRYQPSKLTPPKDAQ
EEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCE
LILDSNYSLAAIGLLSVQAPEMADRIIENFAEHKAL
EEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-threo-3-methylaspartate

Specific reaction: L-threo-3-methylaspartate = L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428631 [H]