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The map label for this gene is trxB [H]

Identifier: 188584777

GI number: 188584777

Start: 159519

End: 160448

Strand: Direct

Name: trxB [H]

Synonym: Nther_0135

Alternate gene names: 188584777

Gene position: 159519-160448 (Clockwise)

Preceding gene: 188584776

Following gene: 188584778

Centisome position: 5.04

GC content: 38.82

Gene sequence:

>930_bases
ATGACGGATCAATTTGATCGGGAAAATATTTATGATGTAGCAATCATTGGTAGTGGCCCCGGAGGTCTGACCGCTGCAAT
TTACGCCACAAGAGCAGGATTAAAGGTTCTGATGATTGAACGCATGGCTCCAGGAGGACAATTATTAAACACTGAAGAGG
TAGATAATTTTCCCGGATTTCCGGACGGAACTACTGGAGTAGAATTGGCACAAAAATTAGAAAAACAAGCCCGAAGGTTC
GGGACCGAGCTAAAAATGGGAGAAGTCATTGAAACAAATCTTTCTGGATCTGAAAAAATGATCAAAACAAGAGATGAAGT
CTATAAAGCAAAATCTGTAATTATTGCCACAGGTGAAAGCCCTACTGAATTATCGGCTCCTGGGGAACAGAACCTAAAGG
GTCGAGGGGTTTCTTATTGTGCTATTTGCGATGGAGCTTTCTTTAAAAACAAAAATGTTGCTGTAGTTGGAGGCGGAGAT
TCGGCAGTAGAATCTGCTCTTTATCTCAGTAGACTAGCCAGTCAAGTCACTTTAATTCACAGACGGGATCAGTTGAGGGC
AGTAGAGTATCTTAAGAAAAGAGCTATTGATTGTGAAAATTTAGAAATAAAATATAATACAGTTGTTAAGGAAATTCAAG
GCGAGCAAAAAGTGGAATCTCTATTGGTGGAGGATGTAAACACCCAGGCTCGTGAGACACTAAATTGTCAAGGAATATTT
GTTTATGTAGGCGCTCATCCTAATACAGATTTTCTTTCAAATCAATTAGATTTAGAAGATGGCTATTTAGTTACAAGTGA
AACAATGGAGACTAATTTGAAGGGTGTTTTTGCTGTTGGTGATGTCAGAAAAAAAGAATTGAGACAGATAGTTACTGCTG
TCTCTGATGGAGCAATTGCTGCTTTTCACGCTGAAAAATTATTATCATAA

Upstream 100 bases:

>100_bases
CATATGAATTGAATCGCCTAACTTTTAGCATAGCATTTGACAATAGGAAAAAATACAGTTACAATCAAAATACCCCCAGG
GGTATCAGGAGGTGCATGTA

Downstream 100 bases:

>100_bases
TTTTAAAAATGGAAGGAGAGATTAATATGTCAAAAATTTTAGAAGTGAATGATACAAACTTTAAGGAGCAGGTACTGGAA
GCTGATAAACCTGTATTAGT

Product: thioredoxin reductase (NADPH)

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTDQFDRENIYDVAIIGSGPGGLTAAIYATRAGLKVLMIERMAPGGQLLNTEEVDNFPGFPDGTTGVELAQKLEKQARRF
GTELKMGEVIETNLSGSEKMIKTRDEVYKAKSVIIATGESPTELSAPGEQNLKGRGVSYCAICDGAFFKNKNVAVVGGGD
SAVESALYLSRLASQVTLIHRRDQLRAVEYLKKRAIDCENLEIKYNTVVKEIQGEQKVESLLVEDVNTQARETLNCQGIF
VYVGAHPNTDFLSNQLDLEDGYLVTSETMETNLKGVFAVGDVRKKELRQIVTAVSDGAIAAFHAEKLLS

Sequences:

>Translated_309_residues
MTDQFDRENIYDVAIIGSGPGGLTAAIYATRAGLKVLMIERMAPGGQLLNTEEVDNFPGFPDGTTGVELAQKLEKQARRF
GTELKMGEVIETNLSGSEKMIKTRDEVYKAKSVIIATGESPTELSAPGEQNLKGRGVSYCAICDGAFFKNKNVAVVGGGD
SAVESALYLSRLASQVTLIHRRDQLRAVEYLKKRAIDCENLEIKYNTVVKEIQGEQKVESLLVEDVNTQARETLNCQGIF
VYVGAHPNTDFLSNQLDLEDGYLVTSETMETNLKGVFAVGDVRKKELRQIVTAVSDGAIAAFHAEKLLS
>Mature_308_residues
TDQFDRENIYDVAIIGSGPGGLTAAIYATRAGLKVLMIERMAPGGQLLNTEEVDNFPGFPDGTTGVELAQKLEKQARRFG
TELKMGEVIETNLSGSEKMIKTRDEVYKAKSVIIATGESPTELSAPGEQNLKGRGVSYCAICDGAFFKNKNVAVVGGGDS
AVESALYLSRLASQVTLIHRRDQLRAVEYLKKRAIDCENLEIKYNTVVKEIQGEQKVESLLVEDVNTQARETLNCQGIFV
YVGAHPNTDFLSNQLDLEDGYLVTSETMETNLKGVFAVGDVRKKELRQIVTAVSDGAIAAFHAEKLLS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=304, Percent_Identity=41.7763157894737, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI87081763, Length=310, Percent_Identity=34.8387096774194, Blast_Score=158, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6320560, Length=311, Percent_Identity=40.5144694533762, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=38.3386581469649, Blast_Score=210, Evalue=2e-55,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33690; Mature: 33558

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQFDRENIYDVAIIGSGPGGLTAAIYATRAGLKVLMIERMAPGGQLLNTEEVDNFPGF
CCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCCCC
PDGTTGVELAQKLEKQARRFGTELKMGEVIETNLSGSEKMIKTRDEVYKAKSVIIATGES
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHEEEEEEECCCC
PTELSAPGEQNLKGRGVSYCAICDGAFFKNKNVAVVGGGDSAVESALYLSRLASQVTLIH
CCCCCCCCCCCCCCCCCEEEEEECCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
RRDQLRAVEYLKKRAIDCENLEIKYNTVVKEIQGEQKVESLLVEDVNTQARETLNCQGIF
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCCCEEE
VYVGAHPNTDFLSNQLDLEDGYLVTSETMETNLKGVFAVGDVRKKELRQIVTAVSDGAIA
EEEECCCCHHHHCCCCCCCCCEEEECHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCEE
AFHAEKLLS
EEHHHHHCC
>Mature Secondary Structure 
TDQFDRENIYDVAIIGSGPGGLTAAIYATRAGLKVLMIERMAPGGQLLNTEEVDNFPGF
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCCCC
PDGTTGVELAQKLEKQARRFGTELKMGEVIETNLSGSEKMIKTRDEVYKAKSVIIATGES
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHHHHEEEEEEECCCC
PTELSAPGEQNLKGRGVSYCAICDGAFFKNKNVAVVGGGDSAVESALYLSRLASQVTLIH
CCCCCCCCCCCCCCCCCEEEEEECCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
RRDQLRAVEYLKKRAIDCENLEIKYNTVVKEIQGEQKVESLLVEDVNTQARETLNCQGIF
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCCCEEE
VYVGAHPNTDFLSNQLDLEDGYLVTSETMETNLKGVFAVGDVRKKELRQIVTAVSDGAIA
EEEECCCCHHHHCCCCCCCCCEEEECHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCEE
AFHAEKLLS
EEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]