BacMap

Definition	Natranaerobius thermophilus JW/NM-WN-LF, complete genome.
Accession	NC_010718
Length	3,165,557

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The map label for this gene is ftsH

Identifier: 188584723

GI number: 188584723

Start: 97364

End: 99445

Strand: Direct

Name: ftsH

Synonym: Nther_0081

Alternate gene names: 188584723

Gene position: 97364-99445 (Clockwise)

Preceding gene: 188584722

Following gene: 188584724

Centisome position: 3.08

GC content: 38.9

Gene sequence:

>2082_bases
TTGAACCGTTTTACCAGACAAGCAGTACTGTATTTACTGATACTGATGATTGTAGTTGGAATTTTTCAGCAACTTAACCA
AGAACCAGAAGCGGAAGAAGACTTATTTTACAATGAATTTCTCAATAAAGTAGAGGCAGGAGAAGTAGATAGAGTAGATA
TTACTGAGAGGGATATTGAAGGTGAATTGACCGATGGTACTTCATTTGTGACCAGGGATCCAGGCGATCCAGAGTTGATT
GAAACCTTAAAAGAGTACGAAGTTAATATTAAAGACCATGAAGTCCCCGGTCCTCCTTGGTGGGCGTCACTATTTACCTA
TATTATTCCTTTTGTATTACTAATAGCGATATTTTTCTTTTTTATGCAACAATCCCAAGGCGGCGGTGGACGTATGATGA
ATTTTGGAAAAAGTAAAGCCAAACTTCACGAAGGCGATCAGAAAAGTAACGTTAAGTTTCATGATGTGGCAGGTGCCGAC
GAAGAAAAGGAAGAATTAGTTGAGGTAGTGAATTTCTTAAAAGAGCCTCAGAAGTTTATCGATTTGGGTGCTAGAATTCC
GAAAGGAGTTTTACTAGTTGGGCCTCCCGGTACAGGAAAAACACTACTTGGTAGAGCTGTAGCTGGTGAAGCGGGTGTAC
CATTCTTTAGCATTAGTGGTTCAGACTTTGTAGAGATGTTTGTAGGAGTTGGAGCATCCAGGGTACGTGATTTATTCGAA
AATGCTAAGAAAAATTCACCATGTATAGTGTTCATTGATGAAATTGATGCTGTAGGTCGACAAAGAGGCGCCGGATTAGG
CGGAGGTCATGATGAGCGTGAACAGACTTTAAACCAGTTACTTGTTGAAATGGATGGTTTCGACGTCAATGAAGGTATTA
TTGTAATGGCTGCAACAAACAGATCTGATATCCTCGACCCAGCCTTACAAAGACCGGGACGTTTTGATAGACAAATAACT
GTCAATGCTCCTGACTTAAAAGGACGTGAAGAAATACTAAAGGTCCATGCCCGTGATAAACCTCTAGAAGATAACGTAGA
TTTAAAAGTAGTGGCTCGAAGAACTCCAGGCTTTACGGGTGCAGATTTGGAAAACTTAGTCAATGAAGCAGCTATTTATG
CTGCTAGAAGAAACAAGAATAGAATTGGTATGAAAGAACTTGAAGGGGCAATAGATCGTGTGATTGCAGGTACAGAGAAG
AAAAGTCGTGTAATCAGCGAATTTGAAAAGAAAATTGTTGCCTATCACGAAGCCGGTCACGCCATTGTGGGATATCTTCT
ACCACATACTGACCCCGTTCACAAGGTTTCTATTATTCCACGCGGAGCAGCCGGTGGTTTCACATTAATGTTACCAGAAG
AAGATAGACAATTTATGACGAAAACTGAACTATTGGAACGTGTGAGCACTTTACTAGGAGGAAGAGTTGCCGAAGAGCTC
AAACTCAAAGAGATTAGTACTGGAGCTCAAAACGATCTTGAGAGAGCAACTACCATTGTGAGACAAATGATAATGGAATA
CGGCATGAGTGAAAATTTAGGACCCATCACTTTAGGTCAAAAACAAGGTCAGGTCTTCCTGGGAAGAGATATTGCTAGAG
ATAAGGATTACAGTGAAAATATTGCTTATGCAATAGATAAAGAAATAAGAAACATGGTTGACAGTTCTTATCAAGAAGCC
AGGGAAACATTAGAAGAAAATATTGACAAACTCGAAAAAATTGCTCAGGCCTTGATGGAAAGAGAAACCTTGGTGGCCAA
AGAAATTAAAATGTTAATGGAAGGAAAAGACTTGCCTCCTATTGAAGAAAGTGAAGACACAGAAACATTAGATTTTTTAG
TTGACGAACAACAAGATACGAAATCTGAATCAGACAATGAACAACAGTCCCAAGAAAACCAAGCAGATAACAATCAAAAT
GATTCAACAACAGAATTTGACGACGAACAACAAACTAATGATGACAATCGACCTGAAGACGATGAAGATAACGAAGAAGA
TAAAAACAAGGGGAACAACGACTTCAATCTTAAAATAGACTACAATAAAGAAGATAAAGATAACAAAGATAAAGATAAGT
AA

Upstream 100 bases:

>100_bases
TTAATGAAAATTTGATTAGTTGTTTTAGAGAATATTTTATGATAAAATACCATGATGCATATATTGTAGAGTTGTGTGTT
TCAAGAGAGGAGGGCTCTAG

Downstream 100 bases:

>100_bases
CAATTGGATGAAACTCTCTGACAGATGAATAAAGCTTGCTACCCGGACCTAAAATGGCCGGGATAGCAAGCCTTTATCTT
AATATCACAAATGTTTTGAA

Product: FtsH-2 peptidase. Metallo peptidase. MEROPS family M41, membrane protease FtsH catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 693; Mature: 693

Protein sequence:

>693_residues
MNRFTRQAVLYLLILMIVVGIFQQLNQEPEAEEDLFYNEFLNKVEAGEVDRVDITERDIEGELTDGTSFVTRDPGDPELI
ETLKEYEVNIKDHEVPGPPWWASLFTYIIPFVLLIAIFFFFMQQSQGGGGRMMNFGKSKAKLHEGDQKSNVKFHDVAGAD
EEKEELVEVVNFLKEPQKFIDLGARIPKGVLLVGPPGTGKTLLGRAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFE
NAKKNSPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDVNEGIIVMAATNRSDILDPALQRPGRFDRQIT
VNAPDLKGREEILKVHARDKPLEDNVDLKVVARRTPGFTGADLENLVNEAAIYAARRNKNRIGMKELEGAIDRVIAGTEK
KSRVISEFEKKIVAYHEAGHAIVGYLLPHTDPVHKVSIIPRGAAGGFTLMLPEEDRQFMTKTELLERVSTLLGGRVAEEL
KLKEISTGAQNDLERATTIVRQMIMEYGMSENLGPITLGQKQGQVFLGRDIARDKDYSENIAYAIDKEIRNMVDSSYQEA
RETLEENIDKLEKIAQALMERETLVAKEIKMLMEGKDLPPIEESEDTETLDFLVDEQQDTKSESDNEQQSQENQADNNQN
DSTTEFDDEQQTNDDNRPEDDEDNEEDKNKGNNDFNLKIDYNKEDKDNKDKDK

Sequences:

>Translated_693_residues
MNRFTRQAVLYLLILMIVVGIFQQLNQEPEAEEDLFYNEFLNKVEAGEVDRVDITERDIEGELTDGTSFVTRDPGDPELI
ETLKEYEVNIKDHEVPGPPWWASLFTYIIPFVLLIAIFFFFMQQSQGGGGRMMNFGKSKAKLHEGDQKSNVKFHDVAGAD
EEKEELVEVVNFLKEPQKFIDLGARIPKGVLLVGPPGTGKTLLGRAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFE
NAKKNSPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDVNEGIIVMAATNRSDILDPALQRPGRFDRQIT
VNAPDLKGREEILKVHARDKPLEDNVDLKVVARRTPGFTGADLENLVNEAAIYAARRNKNRIGMKELEGAIDRVIAGTEK
KSRVISEFEKKIVAYHEAGHAIVGYLLPHTDPVHKVSIIPRGAAGGFTLMLPEEDRQFMTKTELLERVSTLLGGRVAEEL
KLKEISTGAQNDLERATTIVRQMIMEYGMSENLGPITLGQKQGQVFLGRDIARDKDYSENIAYAIDKEIRNMVDSSYQEA
RETLEENIDKLEKIAQALMERETLVAKEIKMLMEGKDLPPIEESEDTETLDFLVDEQQDTKSESDNEQQSQENQADNNQN
DSTTEFDDEQQTNDDNRPEDDEDNEEDKNKGNNDFNLKIDYNKEDKDNKDKDK
>Mature_693_residues
MNRFTRQAVLYLLILMIVVGIFQQLNQEPEAEEDLFYNEFLNKVEAGEVDRVDITERDIEGELTDGTSFVTRDPGDPELI
ETLKEYEVNIKDHEVPGPPWWASLFTYIIPFVLLIAIFFFFMQQSQGGGGRMMNFGKSKAKLHEGDQKSNVKFHDVAGAD
EEKEELVEVVNFLKEPQKFIDLGARIPKGVLLVGPPGTGKTLLGRAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFE
NAKKNSPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDVNEGIIVMAATNRSDILDPALQRPGRFDRQIT
VNAPDLKGREEILKVHARDKPLEDNVDLKVVARRTPGFTGADLENLVNEAAIYAARRNKNRIGMKELEGAIDRVIAGTEK
KSRVISEFEKKIVAYHEAGHAIVGYLLPHTDPVHKVSIIPRGAAGGFTLMLPEEDRQFMTKTELLERVSTLLGGRVAEEL
KLKEISTGAQNDLERATTIVRQMIMEYGMSENLGPITLGQKQGQVFLGRDIARDKDYSENIAYAIDKEIRNMVDSSYQEA
RETLEENIDKLEKIAQALMERETLVAKEIKMLMEGKDLPPIEESEDTETLDFLVDEQQDTKSESDNEQQSQENQADNNQN
DSTTEFDDEQQTNDDNRPEDDEDNEEDKNKGNNDFNLKIDYNKEDKDNKDKDK

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=495, Percent_Identity=49.6969696969697, Blast_Score=473, Evalue=1e-133,
Organism=Homo sapiens, GI4507173, Length=616, Percent_Identity=39.1233766233766, Blast_Score=423, Evalue=1e-118,
Organism=Homo sapiens, GI21327685, Length=454, Percent_Identity=49.3392070484581, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI7657689, Length=454, Percent_Identity=49.3392070484581, Blast_Score=421, Evalue=1e-118,
Organism=Homo sapiens, GI4506209, Length=262, Percent_Identity=43.1297709923664, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI24497435, Length=259, Percent_Identity=41.3127413127413, Blast_Score=207, Evalue=4e-53,
Organism=Homo sapiens, GI21361144, Length=241, Percent_Identity=42.3236514522822, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI6005942, Length=238, Percent_Identity=43.6974789915966, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI195539395, Length=256, Percent_Identity=38.671875, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI5729991, Length=264, Percent_Identity=39.0151515151515, Blast_Score=190, Evalue=5e-48,
Organism=Homo sapiens, GI89064750, Length=264, Percent_Identity=39.0151515151515, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI24430155, Length=264, Percent_Identity=39.0151515151515, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI45643123, Length=275, Percent_Identity=38.1818181818182, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI45643125, Length=275, Percent_Identity=38.1818181818182, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI24430151, Length=287, Percent_Identity=33.7979094076655, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI157671927, Length=226, Percent_Identity=40.7079646017699, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI40806173, Length=310, Percent_Identity=36.4516129032258, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI24497618, Length=259, Percent_Identity=39.3822393822394, Blast_Score=170, Evalue=5e-42,
Organism=Homo sapiens, GI4505725, Length=220, Percent_Identity=40.4545454545455, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI153792536, Length=240, Percent_Identity=39.5833333333333, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI229577436, Length=248, Percent_Identity=38.7096774193548, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI5901990, Length=239, Percent_Identity=40.1673640167364, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI194018488, Length=256, Percent_Identity=38.28125, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI14149767, Length=250, Percent_Identity=36.4, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI62177112, Length=250, Percent_Identity=36.4, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI17865802, Length=254, Percent_Identity=37.7952755905512, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI226371754, Length=237, Percent_Identity=37.1308016877637, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI7019569, Length=254, Percent_Identity=35.0393700787402, Blast_Score=143, Evalue=7e-34,
Organism=Homo sapiens, GI31377644, Length=238, Percent_Identity=36.9747899159664, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI31742536, Length=235, Percent_Identity=33.6170212765957, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI112789543, Length=235, Percent_Identity=33.6170212765957, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI11875211, Length=233, Percent_Identity=38.1974248927039, Blast_Score=131, Evalue=3e-30,
Organism=Homo sapiens, GI40806170, Length=233, Percent_Identity=38.1974248927039, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI156564401, Length=222, Percent_Identity=39.1891891891892, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI310125280, Length=222, Percent_Identity=38.7387387387387, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI310125282, Length=222, Percent_Identity=38.7387387387387, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI64084766, Length=230, Percent_Identity=28.2608695652174, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI116292174, Length=255, Percent_Identity=30.1960784313725, Blast_Score=86, Evalue=2e-16,
Organism=Escherichia coli, GI1789568, Length=601, Percent_Identity=52.4126455906822, Blast_Score=630, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71994521, Length=440, Percent_Identity=53.8636363636364, Blast_Score=452, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI115534323, Length=460, Percent_Identity=45.4347826086956, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17554264, Length=442, Percent_Identity=47.2850678733032, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17554786, Length=259, Percent_Identity=42.4710424710425, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17563248, Length=258, Percent_Identity=43.4108527131783, Blast_Score=216, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI25144278, Length=259, Percent_Identity=42.0849420849421, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI25144281, Length=259, Percent_Identity=42.0849420849421, Blast_Score=209, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI17508701, Length=260, Percent_Identity=40.3846153846154, Blast_Score=202, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17532375, Length=233, Percent_Identity=38.6266094420601, Blast_Score=193, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71987364, Length=228, Percent_Identity=43.421052631579, Blast_Score=192, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI71987372, Length=228, Percent_Identity=43.421052631579, Blast_Score=192, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17563250, Length=259, Percent_Identity=39.3822393822394, Blast_Score=185, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17531535, Length=247, Percent_Identity=41.7004048582996, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=259, Percent_Identity=38.996138996139, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17505546, Length=259, Percent_Identity=38.6100386100386, Blast_Score=181, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17508053, Length=254, Percent_Identity=38.5826771653543, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI193206114, Length=246, Percent_Identity=39.4308943089431, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI133931034, Length=246, Percent_Identity=39.4308943089431, Blast_Score=163, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI193206116, Length=246, Percent_Identity=39.4308943089431, Blast_Score=162, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17537217, Length=283, Percent_Identity=35.3356890459364, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17570397, Length=168, Percent_Identity=48.8095238095238, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32566590, Length=168, Percent_Identity=48.8095238095238, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25153574, Length=225, Percent_Identity=37.3333333333333, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=37.3333333333333, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI86561515, Length=248, Percent_Identity=37.5, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17562804, Length=232, Percent_Identity=35.7758620689655, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI133901658, Length=220, Percent_Identity=40, Blast_Score=138, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI133901662, Length=220, Percent_Identity=40.4545454545455, Blast_Score=138, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI25146157, Length=234, Percent_Identity=37.6068376068376, Blast_Score=128, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI32563584, Length=250, Percent_Identity=38, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17508421, Length=238, Percent_Identity=38.2352941176471, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17560432, Length=232, Percent_Identity=36.6379310344828, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17541226, Length=240, Percent_Identity=32.0833333333333, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17541224, Length=240, Percent_Identity=32.0833333333333, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71990294, Length=208, Percent_Identity=29.8076923076923, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320854, Length=542, Percent_Identity=44.6494464944649, Blast_Score=455, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6323736, Length=520, Percent_Identity=45.9615384615385, Blast_Score=453, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6325281, Length=462, Percent_Identity=45.2380952380952, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322704, Length=258, Percent_Identity=43.0232558139535, Blast_Score=218, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6321390, Length=241, Percent_Identity=42.3236514522822, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6324691, Length=272, Percent_Identity=40.0735294117647, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320077, Length=228, Percent_Identity=43.859649122807, Blast_Score=199, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6324833, Length=249, Percent_Identity=39.7590361445783, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6320197, Length=326, Percent_Identity=32.8220858895706, Blast_Score=187, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6320602, Length=249, Percent_Identity=39.7590361445783, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322651, Length=244, Percent_Identity=38.1147540983607, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=245, Percent_Identity=39.1836734693878, Blast_Score=173, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6321709, Length=275, Percent_Identity=37.8181818181818, Blast_Score=166, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6324000, Length=236, Percent_Identity=38.5593220338983, Blast_Score=163, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6323429, Length=226, Percent_Identity=39.3805309734513, Blast_Score=160, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6325431, Length=246, Percent_Identity=37.8048780487805, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6321465, Length=230, Percent_Identity=36.5217391304348, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6319554, Length=254, Percent_Identity=34.251968503937, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6325183, Length=242, Percent_Identity=34.7107438016529, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320887, Length=251, Percent_Identity=33.4661354581673, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320583, Length=159, Percent_Identity=32.0754716981132, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574878, Length=502, Percent_Identity=49.203187250996, Blast_Score=470, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24665814, Length=500, Percent_Identity=49.4, Blast_Score=469, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24658770, Length=488, Percent_Identity=46.3114754098361, Blast_Score=423, Evalue=1e-118,
Organism=Drosophila melanogaster, GI24639391, Length=441, Percent_Identity=48.9795918367347, Blast_Score=423, Evalue=1e-118,
Organism=Drosophila melanogaster, GI17137738, Length=256, Percent_Identity=43.75, Blast_Score=215, Evalue=8e-56,
Organism=Drosophila melanogaster, GI19920408, Length=259, Percent_Identity=41.3127413127413, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI45554047, Length=170, Percent_Identity=57.0588235294118, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24651451, Length=259, Percent_Identity=40.9266409266409, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17738151, Length=260, Percent_Identity=40.7692307692308, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI161076486, Length=229, Percent_Identity=40.6113537117904, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI17137560, Length=229, Percent_Identity=40.6113537117904, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI161076488, Length=229, Percent_Identity=40.6113537117904, Blast_Score=199, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24660075, Length=235, Percent_Identity=41.7021276595745, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI281365776, Length=235, Percent_Identity=41.7021276595745, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI45552965, Length=235, Percent_Identity=41.7021276595745, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI281361487, Length=244, Percent_Identity=40.1639344262295, Blast_Score=189, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24640100, Length=246, Percent_Identity=39.0243902439024, Blast_Score=187, Evalue=3e-47,
Organism=Drosophila melanogaster, GI18860063, Length=252, Percent_Identity=38.4920634920635, Blast_Score=187, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24663015, Length=256, Percent_Identity=37.5, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24649446, Length=243, Percent_Identity=39.0946502057613, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24652279, Length=190, Percent_Identity=42.6315789473684, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24656825, Length=267, Percent_Identity=38.9513108614232, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24656820, Length=267, Percent_Identity=38.9513108614232, Blast_Score=177, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19921202, Length=228, Percent_Identity=38.5964912280702, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281363136, Length=236, Percent_Identity=36.864406779661, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI78707192, Length=236, Percent_Identity=36.864406779661, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24644145, Length=233, Percent_Identity=39.0557939914163, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI18859657, Length=248, Percent_Identity=37.9032258064516, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281360144, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI281360140, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI281360136, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24644411, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI281360142, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI21357333, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI281360146, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281360138, Length=232, Percent_Identity=36.6379310344828, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI21355121, Length=204, Percent_Identity=35.7843137254902, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI20129529, Length=232, Percent_Identity=35.3448275862069, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24581396, Length=238, Percent_Identity=36.5546218487395, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI20129423, Length=262, Percent_Identity=33.587786259542, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28571849, Length=235, Percent_Identity=38.7234042553192, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571847, Length=235, Percent_Identity=38.7234042553192, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17864540, Length=221, Percent_Identity=38.9140271493213, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28573010, Length=221, Percent_Identity=37.5565610859729, Blast_Score=122, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24639486, Length=283, Percent_Identity=29.3286219081272, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_NATTJ (B2A3Q4)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001916268.1
- ProteinModelPortal:   B2A3Q4
- MEROPS:   M41.021
- GeneID:   6316274
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0081
- HOGENOM:   HBG724153
- OMA:   YDEYLLA
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 77900; Mature: 77900

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 417-417

Signals:

None

Transmembrane regions:

HASH(0x22a788a0)-; HASH(0x403c6454)-;

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFTRQAVLYLLILMIVVGIFQQLNQEPEAEEDLFYNEFLNKVEAGEVDRVDITERDIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GELTDGTSFVTRDPGDPELIETLKEYEVNIKDHEVPGPPWWASLFTYIIPFVLLIAIFFF
CCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FMQQSQGGGGRMMNFGKSKAKLHEGDQKSNVKFHDVAGADEEKEELVEVVNFLKEPQKFI
HHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCHHHHH
DLGARIPKGVLLVGPPGTGKTLLGRAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFE
HHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHH
NAKKNSPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDVNEGIIVMAATN
HHCCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
RSDILDPALQRPGRFDRQITVNAPDLKGREEILKVHARDKPLEDNVDLKVVARRTPGFTG
CCHHCCHHHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
ADLENLVNEAAIYAARRNKNRIGMKELEGAIDRVIAGTEKKSRVISEFEKKIVAYHEAGH
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
AIVGYLLPHTDPVHKVSIIPRGAAGGFTLMLPEEDRQFMTKTELLERVSTLLGGRVAEEL
EEEHHCCCCCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHH
KLKEISTGAQNDLERATTIVRQMIMEYGMSENLGPITLGQKQGQVFLGRDIARDKDYSEN
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEECCHHHCCCCCCCC
IAYAIDKEIRNMVDSSYQEARETLEENIDKLEKIAQALMERETLVAKEIKMLMEGKDLPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IEESEDTETLDFLVDEQQDTKSESDNEQQSQENQADNNQNDSTTEFDDEQQTNDDNRPED
CCCCCCCHHHHHHHCCCHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
DEDNEEDKNKGNNDFNLKIDYNKEDKDNKDKDK
CCCCCHHHHCCCCCEEEEEECCCCCCCCCCCCH
>Mature Secondary Structure
MNRFTRQAVLYLLILMIVVGIFQQLNQEPEAEEDLFYNEFLNKVEAGEVDRVDITERDIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GELTDGTSFVTRDPGDPELIETLKEYEVNIKDHEVPGPPWWASLFTYIIPFVLLIAIFFF
CCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
FMQQSQGGGGRMMNFGKSKAKLHEGDQKSNVKFHDVAGADEEKEELVEVVNFLKEPQKFI
HHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCHHHHH
DLGARIPKGVLLVGPPGTGKTLLGRAVAGEAGVPFFSISGSDFVEMFVGVGASRVRDLFE
HHHCCCCCCEEEECCCCCCHHHHHHHHCCCCCCCEEECCCHHHHHHHHHCCHHHHHHHHH
NAKKNSPCIVFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFDVNEGIIVMAATN
HHCCCCCEEEEECCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECC
RSDILDPALQRPGRFDRQITVNAPDLKGREEILKVHARDKPLEDNVDLKVVARRTPGFTG
CCHHCCHHHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
ADLENLVNEAAIYAARRNKNRIGMKELEGAIDRVIAGTEKKSRVISEFEKKIVAYHEAGH
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
AIVGYLLPHTDPVHKVSIIPRGAAGGFTLMLPEEDRQFMTKTELLERVSTLLGGRVAEEL
EEEHHCCCCCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHH
KLKEISTGAQNDLERATTIVRQMIMEYGMSENLGPITLGQKQGQVFLGRDIARDKDYSEN
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEECCHHHCCCCCCCC
IAYAIDKEIRNMVDSSYQEARETLEENIDKLEKIAQALMERETLVAKEIKMLMEGKDLPP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
IEESEDTETLDFLVDEQQDTKSESDNEQQSQENQADNNQNDSTTEFDDEQQTNDDNRPED
CCCCCCCHHHHHHHCCCHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
DEDNEEDKNKGNNDFNLKIDYNKEDKDNKDKDK
CCCCCHHHHCCCCCEEEEEECCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA