Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 188584656

GI number: 188584656

Start: 24786

End: 25262

Strand: Direct

Name: tadA [H]

Synonym: Nther_0014

Alternate gene names: 188584656

Gene position: 24786-25262 (Clockwise)

Preceding gene: 188584655

Following gene: 188584657

Centisome position: 0.78

GC content: 34.8

Gene sequence:

>477_bases
ATGCCTAGCCATAATAATACAGACAAATATTGGATGCAGCAAGCTATAGATCAAGCCAAACTGGCATATAATAAGGGAGA
AGTTCCTATTGGTGCAGTTATTGTAAAAGATGAACAGTTAATAGCAACTGGTTTCAATAAAAGAGAAACTAGTCAAGATG
CAACAAGTCATGCTGAAATAATTGCAATCCAATCGGCTTGTAACTATCTAGGTGGATGGCGTTTACTGGATTGTACCTTA
TATGTGACAATAGAACCTTGTCCTATGTGTGCAGGAGCGATTTTACAATCTAGGATAACCAAGCTGGTTTTTGGAACTGA
AGACCCAAAAGCATGGGGAGAATTATCAATATCACAATTGTTACAAAACCCCCAACTCAATCATCAAGTTGATATTGTTG
AAGGAATTTGCAAAGAAGAATCAAAAGATATTATTAAGCAATTTTTTCACGAATTAAGAAAGAGAAAAAAGAATTAA

Upstream 100 bases:

>100_bases
TCAATACACTTTACATTGCATTTTAAATATGGTAAAGTGATATACTGCTTAGGAAATAAGTTGGATATTATATTTAATAA
ATATATAGAGGTAGTTAATT

Downstream 100 bases:

>100_bases
TTTTAAATATAACCAGATTGTTATTAAAATTTTGATACTAGTTTTTTCTCTAATAATGGTGGAGAGATGGCCGAGTCTGG
CTTAAGGCGCTCGACTCGAA

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MPSHNNTDKYWMQQAIDQAKLAYNKGEVPIGAVIVKDEQLIATGFNKRETSQDATSHAEIIAIQSACNYLGGWRLLDCTL
YVTIEPCPMCAGAILQSRITKLVFGTEDPKAWGELSISQLLQNPQLNHQVDIVEGICKEESKDIIKQFFHELRKRKKN

Sequences:

>Translated_158_residues
MPSHNNTDKYWMQQAIDQAKLAYNKGEVPIGAVIVKDEQLIATGFNKRETSQDATSHAEIIAIQSACNYLGGWRLLDCTL
YVTIEPCPMCAGAILQSRITKLVFGTEDPKAWGELSISQLLQNPQLNHQVDIVEGICKEESKDIIKQFFHELRKRKKN
>Mature_157_residues
PSHNNTDKYWMQQAIDQAKLAYNKGEVPIGAVIVKDEQLIATGFNKRETSQDATSHAEIIAIQSACNYLGGWRLLDCTLY
VTIEPCPMCAGAILQSRITKLVFGTEDPKAWGELSISQLLQNPQLNHQVDIVEGICKEESKDIIKQFFHELRKRKKN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=157, Percent_Identity=29.9363057324841, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI145693172, Length=151, Percent_Identity=41.7218543046358, Blast_Score=140, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17554608, Length=120, Percent_Identity=39.1666666666667, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17541138, Length=152, Percent_Identity=33.5526315789474, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325319, Length=147, Percent_Identity=36.734693877551, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=151, Percent_Identity=29.1390728476821, Blast_Score=68, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=29.6551724137931, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17832; Mature: 17700

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSHNNTDKYWMQQAIDQAKLAYNKGEVPIGAVIVKDEQLIATGFNKRETSQDATSHAEI
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCCCCCCCCHHHHHHH
IAIQSACNYLGGWRLLDCTLYVTIEPCPMCAGAILQSRITKLVFGTEDPKAWGELSISQL
HHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LQNPQLNHQVDIVEGICKEESKDIIKQFFHELRKRKKN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSHNNTDKYWMQQAIDQAKLAYNKGEVPIGAVIVKDEQLIATGFNKRETSQDATSHAEI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCCCCCCCCHHHHHHH
IAIQSACNYLGGWRLLDCTLYVTIEPCPMCAGAILQSRITKLVFGTEDPKAWGELSISQL
HHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LQNPQLNHQVDIVEGICKEESKDIIKQFFHELRKRKKN
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]