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The map label for this gene is galU [H]

Identifier: 188527506

GI number: 188527506

Start: 697700

End: 698521

Strand: Reverse

Name: galU [H]

Synonym: HPSH_03630

Alternate gene names: 188527506

Gene position: 698521-697700 (Counterclockwise)

Preceding gene: 188527507

Following gene: 188527505

Centisome position: 43.43

GC content: 42.7

Gene sequence:

>822_bases
ATGATTAAAAAATGCCTTTTTCCTGCCGCTGGCTACGGCACGCGCTTTTTGCCGATCACTAAAACCATTCCTAAAGAAAT
GCTGCCCATTGTGGATAAGCCTTTAATCCAATACGCTGTAGAAGAAGCGATGGAAGCAGGCTGTGAAGTGATGGCGATCG
TTACAGGCAGAAACAAGCGCAGTTTAGAAGATTATTTTGACACGAGCTATGAAATAGAGCATCAAATCCAAGGCACTAAC
AAAGAAAACGCCCTAAAAAGCATTCGTAACATTATAGAAAAATGCTGTTTTTCCTATGTGCGCCAAAAGCAAATGAAAGG
ATTAGGGCATGCGATTTTAACCGGAGAAGCCCTCATAGGCAATGAGCCTTTTGCGGTGATTTTAGCCGATGACTTATGCA
TAAGCCATGATCACCCAAGCGTGCTAAAGCAAATGATTTCATTGTATCAAAAATACCAATGCTCCATTGTAGCCATTGAA
GAAGTGGCACTAGAAGAAGTCTCAAAATACGGCGTGATTAGGGGCGAATGGTTAGAAGAGGGGGTGTATGAGATTAAAGA
CATGGTGGAAAAACCAAGCCAAGAAGACGCCCCAAGCAATCTAGCCGTGATAGGGCGCTACATTCTAACCCCGGATATTT
TTGAAATTTTAAGCGAGACGAAACCGGGCAAAAACAATGAAATCCAAATCACAGACGCCTTACTCACTCAAGCCAAAAGA
AAACGGATCATCGCTTACCAATTCAAGGGCAAACGATACGATTGCGGGAGCGTGGAAGGCTATATTGAAGCGAGTAACGC
TTATTATAAAAAACGCTTGTAA

Upstream 100 bases:

>100_bases
TTAGGGTCATGCGCAATTACTTGATTTATCAAGAAATTTTTGGGAATTTCATCCCTGTTGATGCATTTTTAGAACAAACT
CTTAACTCAAAGGACAAACC

Downstream 100 bases:

>100_bases
ATCTTATCAACATGGGCAATTTAGCGTATTATGCTTACATGTATTTGATCCTCTTTATATGCTTGCTGCCTGTGTTATTG
GTGGGGCTTGCTTGGAGGCT

Product: UDP-glucose pyrophosphorylase (galU)

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKRSLEDYFDTSYEIEHQIQGTN
KENALKSIRNIIEKCCFSYVRQKQMKGLGHAILTGEALIGNEPFAVILADDLCISHDHPSVLKQMISLYQKYQCSIVAIE
EVALEEVSKYGVIRGEWLEEGVYEIKDMVEKPSQEDAPSNLAVIGRYILTPDIFEILSETKPGKNNEIQITDALLTQAKR
KRIIAYQFKGKRYDCGSVEGYIEASNAYYKKRL

Sequences:

>Translated_273_residues
MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKRSLEDYFDTSYEIEHQIQGTN
KENALKSIRNIIEKCCFSYVRQKQMKGLGHAILTGEALIGNEPFAVILADDLCISHDHPSVLKQMISLYQKYQCSIVAIE
EVALEEVSKYGVIRGEWLEEGVYEIKDMVEKPSQEDAPSNLAVIGRYILTPDIFEILSETKPGKNNEIQITDALLTQAKR
KRIIAYQFKGKRYDCGSVEGYIEASNAYYKKRL
>Mature_273_residues
MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKRSLEDYFDTSYEIEHQIQGTN
KENALKSIRNIIEKCCFSYVRQKQMKGLGHAILTGEALIGNEPFAVILADDLCISHDHPSVLKQMISLYQKYQCSIVAIE
EVALEEVSKYGVIRGEWLEEGVYEIKDMVEKPSQEDAPSNLAVIGRYILTPDIFEILSETKPGKNNEIQITDALLTQAKR
KRIIAYQFKGKRYDCGSVEGYIEASNAYYKKRL

Specific function: May play a role in stationary phase survival [H]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=277, Percent_Identity=42.2382671480144, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1788355, Length=281, Percent_Identity=38.4341637010676, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1788351, Length=268, Percent_Identity=26.865671641791, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790224, Length=273, Percent_Identity=27.4725274725275, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 30918; Mature: 30918

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKR
CCCHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
SLEDYFDTSYEIEHQIQGTNKENALKSIRNIIEKCCFSYVRQKQMKGLGHAILTGEALIG
HHHHHHCCCEEEEHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCEEEC
NEPFAVILADDLCISHDHPSVLKQMISLYQKYQCSIVAIEEVALEEVSKYGVIRGEWLEE
CCCEEEEEECCEEECCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCHHHHHH
GVYEIKDMVEKPSQEDAPSNLAVIGRYILTPDIFEILSETKPGKNNEIQITDALLTQAKR
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEHHHHHHHHHH
KRIIAYQFKGKRYDCGSVEGYIEASNAYYKKRL
CCEEEEEECCCCCCCCCCCCEEECCCCHHHCCC
>Mature Secondary Structure
MIKKCLFPAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAMEAGCEVMAIVTGRNKR
CCCHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
SLEDYFDTSYEIEHQIQGTNKENALKSIRNIIEKCCFSYVRQKQMKGLGHAILTGEALIG
HHHHHHCCCEEEEHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCEEEC
NEPFAVILADDLCISHDHPSVLKQMISLYQKYQCSIVAIEEVALEEVSKYGVIRGEWLEE
CCCEEEEEECCEEECCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCHHHHHH
GVYEIKDMVEKPSQEDAPSNLAVIGRYILTPDIFEILSETKPGKNNEIQITDALLTQAKR
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEHHHHHHHHHH
KRIIAYQFKGKRYDCGSVEGYIEASNAYYKKRL
CCEEEEEECCCCCCCCCCCCEEECCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]