Click here to switch to the map view.

The map label for this gene is murA [H]

Identifier: 188527504

GI number: 188527504

Start: 696010

End: 697278

Strand: Reverse

Name: murA [H]

Synonym: HPSH_03620

Alternate gene names: 188527504

Gene position: 697278-696010 (Counterclockwise)

Preceding gene: 188527505

Following gene: 188527503

Centisome position: 43.35

GC content: 44.92

Gene sequence:

>1269_bases
TTGGATTTTTTAGAGATTGTAGGACAAGTCCCTTTAAAAGGGGGGGTAGAAATTTCAGGGGCGAAAAACTCCGCGCTCCC
CATTTTAGCCGCCACGCTTTTAAGCCAACAGGAAGTCAAAATCAAATCTTTGCCCCAAGTGGTGGATATAAAGGCGATGG
CGTTATTGTTGCAGAATTTAGGCGCAAGCTTAGAATGGCTTGATCCTAACACGCTTCAAATCAGCGCCAAATCCTTGCAC
CACACCGAAGCCACTTACGATTTGGTGCGTAAAATGCGCGCTTCCATTTTGGTTTTAGGCCCACTATTAGCGCGTTTTAA
AGAATGTTTGGTGAGTTTGCCCGGTGGGTGCGCTATAGGAGCAAGGCCTGTGGATTTGCACTTGAAAGCGATGCAACAAT
TAGGGGCTGAAATCAAAATTGAGCAAGGCTATATCCATGCAAAAGCCCCTAAAGGTTTGAAAGGGAATGATATTTTATTT
GATAAGATCAGCGTTACAGGCACAGAAAACGCCCTCATGGCCGCAAGCTTAGCTAAAGGGATCACGCGCATCATTAACGC
CGCTAAAGAGCCAGAAATCACTCAATTGTGTGCGTTTTTACAGAGTGGGGGTGTAGAAATTGAGGGCGTTGGCAGCAGCG
AGTTAAAGATTAGGGGGGTTGAAAATGACGCTTTAAATTTAAAAGACATTCAAATCATACCCGATAGGATTGAAGCAGGC
ACTTATTTATGCGTGGGGGCTATCACTAACAGCCAGCTTAAAATCAATCGCATCATCCCTAACCATCTTCAAGCGATCAC
TGATAAGCTCATAGAAATTGGTTTTTCGCTAGACATTCAAGAAAATTCTATAGAAATTTATCCGGCCCAAAAACGCCAAG
CCTTTGAAATCACCACGAAAGAATACCCAGGCTTTCCCACAGACATGCAAGCGCAATTTATGGCGTTGGCCACGCAGTGT
TTGGGGACGAGCGTGATTGAAGAGACGCTTTTTGAAAACCGCTTCATGCATGCAAGCGAATTGCAACGCTTAGGGGCTAA
TATCAGCCTAAAAACCAATATCGCTACCATTAGCGGATCCACAGAGCTTACCGGAAGCGATGTGATGGCGACCGATTTAA
GGGCTTCTTCGGCTCTCATTTTAGCCGCTTTAGTGGCTAAGGGCGTGAGTAGGGTGCATAGGATTTACCACTTGGATAGG
GGTTATGAGAGATTAGAGGATAAAATCAACGCCTTAGGGGCAAAAGTTGCACGCTTAAAAGAAAAATAA

Upstream 100 bases:

>100_bases
ATTTTGGGCAGGATTTAGAAAACGCTAACCCCAGTCATGCGCAAAAAATCGCTAACGCTACCGGCTTAGCCATTAAGAAT
AAAAAAGAAAAAGGATAGAA

Downstream 100 bases:

>100_bases
CTCAATATTTGGTTACAATAGCTAGAATATTTTTTAACGATACAAGGAGCTTTTATGCGTATTGAGCATGATTTCATTGG
GCAAATGGAAATTAGCGATG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSQQEVKIKSLPQVVDIKAMALLLQNLGASLEWLDPNTLQISAKSLH
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEITQLCAFLQSGGVEIEGVGSSELKIRGVENDALNLKDIQIIPDRIEAG
TYLCVGAITNSQLKINRIIPNHLQAITDKLIEIGFSLDIQENSIEIYPAQKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSVIEETLFENRFMHASELQRLGANISLKTNIATISGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVARLKEK

Sequences:

>Translated_422_residues
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSQQEVKIKSLPQVVDIKAMALLLQNLGASLEWLDPNTLQISAKSLH
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEITQLCAFLQSGGVEIEGVGSSELKIRGVENDALNLKDIQIIPDRIEAG
TYLCVGAITNSQLKINRIIPNHLQAITDKLIEIGFSLDIQENSIEIYPAQKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSVIEETLFENRFMHASELQRLGANISLKTNIATISGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVARLKEK
>Mature_422_residues
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSQQEVKIKSLPQVVDIKAMALLLQNLGASLEWLDPNTLQISAKSLH
HTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILF
DKISVTGTENALMAASLAKGITRIINAAKEPEITQLCAFLQSGGVEIEGVGSSELKIRGVENDALNLKDIQIIPDRIEAG
TYLCVGAITNSQLKINRIIPNHLQAITDKLIEIGFSLDIQENSIEIYPAQKRQAFEITTKEYPGFPTDMQAQFMALATQC
LGTSVIEETLFENRFMHASELQRLGANISLKTNIATISGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDR
GYERLEDKINALGAKVARLKEK

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=46.7933491686461, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45721; Mature: 45721

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSQQEVKIKSLPQVVDIKAMALLLQNL
CCHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHH
GASLEWLDPNTLQISAKSLHHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIG
CCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILFDKISVTGTENALMAASLAKG
CCCHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHH
ITRIINAAKEPEITQLCAFLQSGGVEIEGVGSSELKIRGVENDALNLKDIQIIPDRIEAG
HHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECCHHCCC
TYLCVGAITNSQLKINRIIPNHLQAITDKLIEIGFSLDIQENSIEIYPAQKRQAFEITTK
CEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCEEEEECC
EYPGFPTDMQAQFMALATQCLGTSVIEETLFENRFMHASELQRLGANISLKTNIATISGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEEEECCC
TELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVARLK
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EK
CC
>Mature Secondary Structure
MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSQQEVKIKSLPQVVDIKAMALLLQNL
CCHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHH
GASLEWLDPNTLQISAKSLHHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIG
CCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARPVDLHLKAMQQLGAEIKIEQGYIHAKAPKGLKGNDILFDKISVTGTENALMAASLAKG
CCCHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHH
ITRIINAAKEPEITQLCAFLQSGGVEIEGVGSSELKIRGVENDALNLKDIQIIPDRIEAG
HHHHHHCCCCCCHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECCHHCCC
TYLCVGAITNSQLKINRIIPNHLQAITDKLIEIGFSLDIQENSIEIYPAQKRQAFEITTK
CEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCEEEEECCCCCEEEEECC
EYPGFPTDMQAQFMALATQCLGTSVIEETLFENRFMHASELQRLGANISLKTNIATISGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEEEEECCC
TELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVARLK
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA