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The map label for this gene is acxC [H]

Identifier: 188527455

GI number: 188527455

Start: 640362

End: 640862

Strand: Reverse

Name: acxC [H]

Synonym: HPSH_03365

Alternate gene names: 188527455

Gene position: 640862-640362 (Counterclockwise)

Preceding gene: 188527456

Following gene: 188527454

Centisome position: 39.84

GC content: 42.71

Gene sequence:

>501_bases
ATGTCAAAATACACACAAGAACAAATTAAAAATTTGGTAGAGGGGAACTTGGATTGGAACACTGTCTTAAAAATGCTTAG
CATGCCTAAAGATCATGAAAGATTCCAAATGTATTTGAAGGTGTTGCAAGATAAGGTAGATTTTGATGACAAAATCGTCC
TACCCTTGGGGCCGCATTTGTTTGTGGTGCAAGACCCGCAAAAAAAGTGGGCGATCAAGTGTTCATGCGGTCATGCGTTT
TGCGCTCCAGAGGAGAACTGGAAATTGCATGCAAACATCTATGTGCGCGATACTGCAGAAAAAATGGAAGAGGTGTATCC
TAAACTCTTAGCCAGCGATACTAACTGGCAAGTGTATCGGGAGTATATTTGCCCGGATTGCGGCATCCTTTTAGATGTTG
AAGCCCCAACTCCTTGGTATCCTGTGATCCATGATTTTGAGCCTGATATAGAGGCGTTTTATAAAGATTGGCTAGGCATA
CAGCCCCCAGAAAGACGCTAA

Upstream 100 bases:

>100_bases
GTATTCACCTATGGGTCTAAATACAGGATGGATTTGAATAAATTGCCTGATGTGCGCACGGTTGTGTTGGTTGATGAGAA
ATAAAGAAAGGAGAATGGTT

Downstream 100 bases:

>100_bases
GAGCGCTCAATCCTTTATATGAAGAGGCTTTATGCCTCTTGGCGCTACAAGCTTGGGTTAATTTAACTCAAGCAAATTTT
CTTCACTCCTAACAAATTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MSKYTQEQIKNLVEGNLDWNTVLKMLSMPKDHERFQMYLKVLQDKVDFDDKIVLPLGPHLFVVQDPQKKWAIKCSCGHAF
CAPEENWKLHANIYVRDTAEKMEEVYPKLLASDTNWQVYREYICPDCGILLDVEAPTPWYPVIHDFEPDIEAFYKDWLGI
QPPERR

Sequences:

>Translated_166_residues
MSKYTQEQIKNLVEGNLDWNTVLKMLSMPKDHERFQMYLKVLQDKVDFDDKIVLPLGPHLFVVQDPQKKWAIKCSCGHAF
CAPEENWKLHANIYVRDTAEKMEEVYPKLLASDTNWQVYREYICPDCGILLDVEAPTPWYPVIHDFEPDIEAFYKDWLGI
QPPERR
>Mature_165_residues
SKYTQEQIKNLVEGNLDWNTVLKMLSMPKDHERFQMYLKVLQDKVDFDDKIVLPLGPHLFVVQDPQKKWAIKCSCGHAFC
APEENWKLHANIYVRDTAEKMEEVYPKLLASDTNWQVYREYICPDCGILLDVEAPTPWYPVIHDFEPDIEAFYKDWLGIQ
PPERR

Specific function: Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide [H]

COG id: COG4647

COG function: function code Q; Acetone carboxylase, gamma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016750
- InterPro:   IPR014979 [H]

Pfam domain/function: PF08882 Acetone_carb_G [H]

EC number: =6.4.1.6 [H]

Molecular weight: Translated: 19632; Mature: 19501

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYTQEQIKNLVEGNLDWNTVLKMLSMPKDHERFQMYLKVLQDKVDFDDKIVLPLGPHL
CCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEE
FVVQDPQKKWAIKCSCGHAFCAPEENWKLHANIYVRDTAEKMEEVYPKLLASDTNWQVYR
EEEECCCCCEEEEEECCCEECCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCHHHHH
EYICPDCGILLDVEAPTPWYPVIHDFEPDIEAFYKDWLGIQPPERR
HHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SKYTQEQIKNLVEGNLDWNTVLKMLSMPKDHERFQMYLKVLQDKVDFDDKIVLPLGPHL
CCHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEE
FVVQDPQKKWAIKCSCGHAFCAPEENWKLHANIYVRDTAEKMEEVYPKLLASDTNWQVYR
EEEECCCCCEEEEEECCCEECCCCCCCEEEEEEEEECHHHHHHHHHHHHHCCCCCHHHHH
EYICPDCGILLDVEAPTPWYPVIHDFEPDIEAFYKDWLGIQPPERR
HHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12003937 [H]