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The map label for this gene is coaX [H]

Identifier: 188527293

GI number: 188527293

Start: 482545

End: 483216

Strand: Direct

Name: coaX [H]

Synonym: HPSH_02500

Alternate gene names: 188527293

Gene position: 482545-483216 (Clockwise)

Preceding gene: 188527292

Following gene: 188527294

Centisome position: 30.0

GC content: 39.43

Gene sequence:

>672_bases
ATGCCAGCTAGGCAATCTTTTACAGATTTGAAAAACCTGGTTTTATGCGATATAGGCAACACGCGCATCCATTTCGCGCA
AAATTATCAGCTCTTTTCAAGCGCTAAAGAAGATTTAAAGCGTTTGGGTATTCAAAAGGAAATTTTTTACATTAGCGTGA
ATGAAGAAAATGAAAAAGCCCTTTTAAATTGTTACCCTAACGCTAAAAATATTGCAGGATTTTTTCATTTAGAAACCGAC
TATATAGGGCTTGGGATAGACCGGCAAATGGCGTGTCTAGCGGTAAATAATGGCGTGATCGTGGATGCGGGGAGCGCGAT
TACGATTGATTTAATCCAAGAGAGCAAGCATTTAGGAGGGTGTATTTTACCCGGTTTAGCCCAATATATCCATGCGTATA
AAAAAAGCGCTAAAATTTTAGAGCAACCTTTCAAAGCCTTAGATTCTTTAGAAGTTTTACCTAAAAACACTAGGGACGCC
GTGAATTACGGCATGATTTTAAGCGTCATCTCTTGCATCCAGCATTTAGCCAAAAATCAAAAAATCTATCTTTGTGGGGG
CGATGCGAAGTATTTGAGCGCGTTTTTACCCCATTCTGTTTGCAAGGAGCGTTTGGTTTTTGACGGGATGGAAATCGCTC
TTAAAAAAGCAGGGGTATTAGAATGCAAATGA

Upstream 100 bases:

>100_bases
GCGAGAGAATTTGAACAAAGAGCGAGAGAGCAACAAGAAAGAGATGAAAAAGAGCTTGAAGAAAGAAAAAAAGCTTTAGA
AATGAATAAGAAGTAGGCCT

Downstream 100 bases:

>100_bases
TGCACAATTTGAGTTTTTTGGGCATGTTTTTAGCCGCTTTGAGCATGTCTTTAGGGCATTGCGTGGGCATGTGTGGGGGG
ATTGTGAGCGCGTTTAGTCA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MPARQSFTDLKNLVLCDIGNTRIHFAQNYQLFSSAKEDLKRLGIQKEIFYISVNEENEKALLNCYPNAKNIAGFFHLETD
YIGLGIDRQMACLAVNNGVIVDAGSAITIDLIQESKHLGGCILPGLAQYIHAYKKSAKILEQPFKALDSLEVLPKNTRDA
VNYGMILSVISCIQHLAKNQKIYLCGGDAKYLSAFLPHSVCKERLVFDGMEIALKKAGVLECK

Sequences:

>Translated_223_residues
MPARQSFTDLKNLVLCDIGNTRIHFAQNYQLFSSAKEDLKRLGIQKEIFYISVNEENEKALLNCYPNAKNIAGFFHLETD
YIGLGIDRQMACLAVNNGVIVDAGSAITIDLIQESKHLGGCILPGLAQYIHAYKKSAKILEQPFKALDSLEVLPKNTRDA
VNYGMILSVISCIQHLAKNQKIYLCGGDAKYLSAFLPHSVCKERLVFDGMEIALKKAGVLECK
>Mature_222_residues
PARQSFTDLKNLVLCDIGNTRIHFAQNYQLFSSAKEDLKRLGIQKEIFYISVNEENEKALLNCYPNAKNIAGFFHLETDY
IGLGIDRQMACLAVNNGVIVDAGSAITIDLIQESKHLGGCILPGLAQYIHAYKKSAKILEQPFKALDSLEVLPKNTRDAV
NYGMILSVISCIQHLAKNQKIYLCGGDAKYLSAFLPHSVCKERLVFDGMEIALKKAGVLECK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 24756; Mature: 24625

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARQSFTDLKNLVLCDIGNTRIHFAQNYQLFSSAKEDLKRLGIQKEIFYISVNEENEKA
CCCCCHHHHHHHEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCE
LLNCYPNAKNIAGFFHLETDYIGLGIDRQMACLAVNNGVIVDAGSAITIDLIQESKHLGG
EEEECCCCCCCEEEEEEECCEEEECCCCCEEEEEECCCEEEECCCEEEEEEECCCCCCCC
CILPGLAQYIHAYKKSAKILEQPFKALDSLEVLPKNTRDAVNYGMILSVISCIQHLAKNQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
KIYLCGGDAKYLSAFLPHSVCKERLVFDGMEIALKKAGVLECK
EEEEECCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
PARQSFTDLKNLVLCDIGNTRIHFAQNYQLFSSAKEDLKRLGIQKEIFYISVNEENEKA
CCCCHHHHHHHEEEEECCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCE
LLNCYPNAKNIAGFFHLETDYIGLGIDRQMACLAVNNGVIVDAGSAITIDLIQESKHLGG
EEEECCCCCCCEEEEEEECCEEEECCCCCEEEEEECCCEEEECCCEEEEEEECCCCCCCC
CILPGLAQYIHAYKKSAKILEQPFKALDSLEVLPKNTRDAVNYGMILSVISCIQHLAKNQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
KIYLCGGDAKYLSAFLPHSVCKERLVFDGMEIALKKAGVLECK
EEEEECCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA