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The map label for this gene is pgbB [H]

Identifier: 188527292

GI number: 188527292

Start: 480846

End: 482540

Strand: Direct

Name: pgbB [H]

Synonym: HPSH_02495

Alternate gene names: 188527292

Gene position: 480846-482540 (Clockwise)

Preceding gene: 188527291

Following gene: 188527293

Centisome position: 29.89

GC content: 37.88

Gene sequence:

>1695_bases
ATGAACAAACCATTTTTAATCTTACTCATAGCCCTAATTGTTTTTAGCGGCTGTAACATGAGAAAATACTTCAAACCCGC
TAAACACCAAATTAAAGGCGAAGCGTATTTCCCTAACCATTTGCAAGAAAGCATCGTTTCGTCTAATCGTTATGGAGCCA
TTTTGAAAAATGGAGCGGTTATAGGCGATAAGGGTTTAACGCAGCTAAGAATCGGTAAGAATTTCAATTATGAAAGCAGT
TTTTTAAATGAGAGTCAGGGGTTTTTCATCCTTGCGCAAGATTGTTTGAACAAGATTGATAAAAAAACAAGCAAAAGCAA
GGTGGCTAAGACTGAAGAAACGGAATTGAAATTAAAGGGCGTTGAAGCAGAAGTCCAAGATAAAGTCTGCCATCAAGTGG
AATTGATTAGCTCTAACCCTAACGCCAGCCAGAAATCCATCATTATTCCTTTGGAAACTTTTGCCTTGAGCGCGAGCGTT
AAAGGGAATCTTTTAGCGGTGGTGTTAGCGGACAATTCAGCGAATTTATACGACATCACTTCTCAAAAATTGCTTTTTAG
TGAGAAAGGTTCCCCAAGCACCACGATCAATTCTTTGATGGCGATGCCTATTTTTATGGATACGGTCGTGGTATTCCCCA
TGCTAGATGGGCGCTTGTTAGTCGTGGATTATGTGCATGGAAACCCTACGCCTATTAGAAACATTGTTATCAGCAGCGAT
AAGTTTTTTAATAATATCACCTACCTTATCGTAGATGGCAATAACATGATCGCTTCTACAGGGAAAAGAATACTCTCAGT
AGTGAGCGGTCAAGAGTTCAACTATGATGGGGATATTGTGGATTTGCTTTATGACAAGGGGACTTTATATGTGCTCACGC
TAGACGGGCAGATTTTGCAAATGGATAAGAGTTTGAGGGAATTAAACAGCGTGAAACTGCCCTTTGCTTCGCTCAATACC
ATTGTATTAAACCATAATAAATTGTATTCTTTAGAAAAACGAGGGTATGTGATAGAGGTGGATTTGAATGATTTTAATTC
GTATAATGTCTATAAAACGCCAACTATAGGCAGTTTTAAGTTTTTTTCATCCAATCGTTTGGATAAAGGGGTGTTTTATG
ATAAAAATCGGGTGTATTATGATCGCTACTATTTAGATTATAATAATTTTAAACCCAAGCTTTATCCCGTTGTGGAAAAA
CCTGCATCTGAAAAATCTCAAAAAGGCGAAAAAAGGAACGCTCCTATTTATTTGCAAGAAAGGCATAAAGTCAAAGAAAA
GCCTTTAGAAGAAAACAAAGTTAAGCCAAGAAATAGCGGGTTTGAAGAAGAAGAAGTTAAAGCCAGAAGGCGCGGTATGG
AGCCTATTAACAACCAAAATAATGCTAACAACGAAAATAAAGTAGGCAACGAAAATAACGCTATCCAACGAGGCGAAAAC
AAAAACGCTCCTGTTTCAAAAGAGAATAACCAAAAAGGCACAGAAAACGCTCCTGTCTTAAAAGAGGATAACGCTTTTAA
AGAAGCGCCAAAACTCAGCCCTAAAGAAGAAAAACGCCGCTTGAAAGAAGAAAAGAAAAAAGCCAAAGCCGAACAAAGGG
CGAGAGAATTTGAACAAAGAGCGAGAGAGCAACAAGAAAGAGATGAAAAAGAGCTTGAAGAAAGAAAAAAAGCTTTAGAA
ATGAATAAGAAGTAG

Upstream 100 bases:

>100_bases
TCTGTTTTAAAACATTATGGAATGTTAGAAGATATTCAACAAAACCCTTCCAAACCAACCAATCTAAAAAAAGAAACCAT
TCAAGGAACGCATTGATTTG

Downstream 100 bases:

>100_bases
GCCTATGCCAGCTAGGCAATCTTTTACAGATTTGAAAAACCTGGTTTTATGCGATATAGGCAACACGCGCATCCATTTCG
CGCAAAATTATCAGCTCTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAVIGDKGLTQLRIGKNFNYESS
FLNESQGFFILAQDCLNKIDKKTSKSKVAKTEETELKLKGVEAEVQDKVCHQVELISSNPNASQKSIIIPLETFALSASV
KGNLLAVVLADNSANLYDITSQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQMDKSLRELNSVKLPFASLNT
IVLNHNKLYSLEKRGYVIEVDLNDFNSYNVYKTPTIGSFKFFSSNRLDKGVFYDKNRVYYDRYYLDYNNFKPKLYPVVEK
PASEKSQKGEKRNAPIYLQERHKVKEKPLEENKVKPRNSGFEEEEVKARRRGMEPINNQNNANNENKVGNENNAIQRGEN
KNAPVSKENNQKGTENAPVLKEDNAFKEAPKLSPKEEKRRLKEEKKKAKAEQRAREFEQRAREQQERDEKELEERKKALE
MNKK

Sequences:

>Translated_564_residues
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAVIGDKGLTQLRIGKNFNYESS
FLNESQGFFILAQDCLNKIDKKTSKSKVAKTEETELKLKGVEAEVQDKVCHQVELISSNPNASQKSIIIPLETFALSASV
KGNLLAVVLADNSANLYDITSQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQMDKSLRELNSVKLPFASLNT
IVLNHNKLYSLEKRGYVIEVDLNDFNSYNVYKTPTIGSFKFFSSNRLDKGVFYDKNRVYYDRYYLDYNNFKPKLYPVVEK
PASEKSQKGEKRNAPIYLQERHKVKEKPLEENKVKPRNSGFEEEEVKARRRGMEPINNQNNANNENKVGNENNAIQRGEN
KNAPVSKENNQKGTENAPVLKEDNAFKEAPKLSPKEEKRRLKEEKKKAKAEQRAREFEQRAREQQERDEKELEERKKALE
MNKK
>Mature_564_residues
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAVIGDKGLTQLRIGKNFNYESS
FLNESQGFFILAQDCLNKIDKKTSKSKVAKTEETELKLKGVEAEVQDKVCHQVELISSNPNASQKSIIIPLETFALSASV
KGNLLAVVLADNSANLYDITSQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQMDKSLRELNSVKLPFASLNT
IVLNHNKLYSLEKRGYVIEVDLNDFNSYNVYKTPTIGSFKFFSSNRLDKGVFYDKNRVYYDRYYLDYNNFKPKLYPVVEK
PASEKSQKGEKRNAPIYLQERHKVKEKPLEENKVKPRNSGFEEEEVKARRRGMEPINNQNNANNENKVGNENNAIQRGEN
KNAPVSKENNQKGTENAPVLKEDNAFKEAPKLSPKEEKRRLKEEKKKAKAEQRAREFEQRAREQQERDEKELEERKKALE
MNKK

Specific function: Binds plasminogen, specifically, and in a concentration and lysine-dependent manner. Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin. Acquisition of plasminogen/plasmin could enable H.py

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface (Probable). Note=The plasminogen-binding region is localized on the surface the bacterium (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015943
- InterPro:   IPR011046 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 64333; Mature: 64333

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAV
CCCCHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCCCCHHHHHHHHCCCCCCEEEECCEE
IGDKGLTQLRIGKNFNYESSFLNESQGFFILAQDCLNKIDKKTSKSKVAKTEETELKLKG
ECCCCCEEEEECCCCCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
VEAEVQDKVCHQVELISSNPNASQKSIIIPLETFALSASVKGNLLAVVLADNSANLYDIT
CCHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHEEEEEECCCCEEEEEEECCCCCEEEEC
SQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCC
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQ
CCCCCEEEEEECCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEECCHHHH
MDKSLRELNSVKLPFASLNTIVLNHNKLYSLEKRGYVIEVDLNDFNSYNVYKTPTIGSFK
HHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCCEEEEEECCCCCCCCCEECCCCCCEE
FFSSNRLDKGVFYDKNRVYYDRYYLDYNNFKPKLYPVVEKPASEKSQKGEKRNAPIYLQE
ECCCCCCCCCEEECCCEEEEEEEEEECCCCCCEEEEEECCCCCHHHHCCCCCCCCEEEHH
RHKVKEKPLEENKVKPRNSGFEEEEVKARRRGMEPINNQNNANNENKVGNENNAIQRGEN
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
KNAPVSKENNQKGTENAPVLKEDNAFKEAPKLSPKEEKRRLKEEKKKAKAEQRAREFEQR
CCCCCCCCCCCCCCCCCCEEECCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AREQQERDEKELEERKKALEMNKK
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKPFLILLIALIVFSGCNMRKYFKPAKHQIKGEAYFPNHLQESIVSSNRYGAILKNGAV
CCCCHHHHHHHHHHHCCCCCHHHHCCHHHHCCCCCCCCHHHHHHHHCCCCCCEEEECCEE
IGDKGLTQLRIGKNFNYESSFLNESQGFFILAQDCLNKIDKKTSKSKVAKTEETELKLKG
ECCCCCEEEEECCCCCCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
VEAEVQDKVCHQVELISSNPNASQKSIIIPLETFALSASVKGNLLAVVLADNSANLYDIT
CCHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHEEEEEECCCCEEEEEEECCCCCEEEEC
SQKLLFSEKGSPSTTINSLMAMPIFMDTVVVFPMLDGRLLVVDYVHGNPTPIRNIVISSD
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEECCC
KFFNNITYLIVDGNNMIASTGKRILSVVSGQEFNYDGDIVDLLYDKGTLYVLTLDGQILQ
CCCCCEEEEEECCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEEEECCHHHH
MDKSLRELNSVKLPFASLNTIVLNHNKLYSLEKRGYVIEVDLNDFNSYNVYKTPTIGSFK
HHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCCEEEEEECCCCCCCCCEECCCCCCEE
FFSSNRLDKGVFYDKNRVYYDRYYLDYNNFKPKLYPVVEKPASEKSQKGEKRNAPIYLQE
ECCCCCCCCCEEECCCEEEEEEEEEECCCCCCEEEEEECCCCCHHHHCCCCCCCCEEEHH
RHKVKEKPLEENKVKPRNSGFEEEEVKARRRGMEPINNQNNANNENKVGNENNAIQRGEN
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCC
KNAPVSKENNQKGTENAPVLKEDNAFKEAPKLSPKEEKRRLKEEKKKAKAEQRAREFEQR
CCCCCCCCCCCCCCCCCCEEECCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AREQQERDEKELEERKKALEMNKK
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]