Click here to switch to the map view.

The map label for this gene is typA [H]

Identifier: 188527265

GI number: 188527265

Start: 455069

End: 456868

Strand: Direct

Name: typA [H]

Synonym: HPSH_02360

Alternate gene names: 188527265

Gene position: 455069-456868 (Clockwise)

Preceding gene: 188527264

Following gene: 188527266

Centisome position: 28.29

GC content: 43.33

Gene sequence:

>1800_bases
ATGAAAAATATTAGAAATATCGCTGTAATCGCGCATGTTGATCATGGGAAAACCACTTTAGTAGATGGCTTACTTTCTCA
ATCTGGCACATTTAGTGAGAGAGAAAAAGTGGATGAAAGGGTGATGGATAGCAACGATTTAGAAAGAGAAAGAGGGATTA
CTATCCTGTCTAAAAACACCGCTATTTATTACAAAGGCACTAAAATCAATATCATTGACACTCCTGGGCATGCTGATTTT
GGGGGCGAAGTGGAGCGCGTTTTAAAAATGGTGGATGGGGTGCTTCTCCTAGTGGATGCGCAAGAAGGGGTCATGCCTCA
AACTAAATTCGTGGTTAAAAAGGCTTTGAGTTTTGGGATTTGCCCTATTGTGGTGGTGAATAAAATTGATAAGCCTGCCG
CTGAACCGGATAGAGTGGTGGATGAAGTTTTTGACTTGTTCGTAGCGATGGGGGCTAGCGATAAGCAATTGGATTTCCCT
GTGGTGTATGCTGCTGCTAGAGATGGCTATGCGATGAAAAGTTTAGACGATGAAAAGAAAAATTTAGAGCCTTTGTTTGA
AACGATTTTAGAGCATGTGCCAAGCCCTAGCGGGAGCGTTGATGAGCCTTTGCAAATGCAAATTTTTACGCTTGATTATG
ACAATTATGTGGGCAAAATCGGTATCGCTAGAGTGTTTAATGGCTCGGTTAAAAAGAATGAAAGCGTGCTGTTGATGAAG
AGCGATGGGAGTAAAGAAAATGGCCGTATCACTAAGCTTATAGGCTTTTTAGGACTGGCTAGGACTGAGATCGAAAACGC
TTATGCGGGCGATATTGTAGCGATTGCCGGCTTTAACGCAATGGATGTGGGCGATAGCGTCGTTGATCCTGTTAACCCCA
TGCCTTTAGATCCCATGCATTTAGAAGAGCCTACGATGAGCGTGTATTTCGCCGTCAATGATTCGCCCTTAGCCGGGTTA
GAAGGAAAGCATGTTACTGCTAATAAATTGAAAGACAGGCTCTTGAAAGAAATGCAAACCAATATCGCTATGAAATGCGA
AGAAATGGGCGAAGGCAAGTTTAAAGTGAGCGGGCGTGGGGAATTGCAAATCACTATTTTAGCTGAAAACTTGCGCCGTG
AAGGGTTTGAATTTAGCATTTCACGCCCTGAAGTCATCATTAAAGAAGAAAATGGCGTTAAATGCGAGCCTTTTGAGCAT
TTAGTGATTGACACGCCTCAAGATTTTAGCGGGGCTATCATTGAGAGATTAGGCAAAAGAAAAGCCGAGATGAAAGCGAT
GAATCCCATGAGCGACGGCTATACAAGATTAGAATTTGAAATCCCTGCAAGAGGGCTTATCGGCTATAGGAGCGAGTTTT
TAACCGACACTAAGGGCGAAGGCGTGATGAATCACAGCTTTTTAGAATTCCGCCCTTTTAGCGGGAGCGTGGAATCGCGC
AAAAATGGGGCGCTAATCAGCATGGAAAATGGCGAAGCGACCGCTTTTTCGCTATTCAATATCCAAGAAAGAGGCACGCT
TTTTATCAACCCCCAAACTAAGGTTTATGTGGGCATGGTCATTGGCGAGCACAGCAGGGATAATGATTTAGATGTTAATC
CCATCAAATCCAAGCATTTAACCAACATGAGAGCGAGCGGGAGCGATGATGCGATCAAACTCACCCCGCCTAGGACTATG
GTGTTAGAAAGAGCGTTAGAATGGATTGAAGAAGATGAGATTTTAGAAGTTACCCCCTTGAATTTAAGGATCAGGAAAAA
GATTTTAGACCCCAACATGAGGAAAAGGGCGAAAAAATAA

Upstream 100 bases:

>100_bases
CCATTTTATAGAACAGGATTTAGCCAAAAAATTCCGCCATTTGGGGCTATTATAATATTGTGTTATACTTCTAAATTCAA
TTTTGCTTGTTAGGACACTT

Downstream 100 bases:

>100_bases
ATAGAATTTTTTGGAATGCATGCCAATTTATTCAACCAAAACGCTAGTAAAAAAGATGTTTTTTTGCACAATTTACGCTC
CAATAATGGGCGTTACAAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MKNIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDERVMDSNDLERERGITILSKNTAIYYKGTKINIIDTPGHADF
GGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGICPIVVVNKIDKPAAEPDRVVDEVFDLFVAMGASDKQLDFP
VVYAAARDGYAMKSLDDEKKNLEPLFETILEHVPSPSGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMK
SDGSKENGRITKLIGFLGLARTEIENAYAGDIVAIAGFNAMDVGDSVVDPVNPMPLDPMHLEEPTMSVYFAVNDSPLAGL
EGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRGELQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEH
LVIDTPQDFSGAIIERLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLTDTKGEGVMNHSFLEFRPFSGSVESR
KNGALISMENGEATAFSLFNIQERGTLFINPQTKVYVGMVIGEHSRDNDLDVNPIKSKHLTNMRASGSDDAIKLTPPRTM
VLERALEWIEEDEILEVTPLNLRIRKKILDPNMRKRAKK

Sequences:

>Translated_599_residues
MKNIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDERVMDSNDLERERGITILSKNTAIYYKGTKINIIDTPGHADF
GGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGICPIVVVNKIDKPAAEPDRVVDEVFDLFVAMGASDKQLDFP
VVYAAARDGYAMKSLDDEKKNLEPLFETILEHVPSPSGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMK
SDGSKENGRITKLIGFLGLARTEIENAYAGDIVAIAGFNAMDVGDSVVDPVNPMPLDPMHLEEPTMSVYFAVNDSPLAGL
EGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRGELQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEH
LVIDTPQDFSGAIIERLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLTDTKGEGVMNHSFLEFRPFSGSVESR
KNGALISMENGEATAFSLFNIQERGTLFINPQTKVYVGMVIGEHSRDNDLDVNPIKSKHLTNMRASGSDDAIKLTPPRTM
VLERALEWIEEDEILEVTPLNLRIRKKILDPNMRKRAKK
>Mature_599_residues
MKNIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDERVMDSNDLERERGITILSKNTAIYYKGTKINIIDTPGHADF
GGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGICPIVVVNKIDKPAAEPDRVVDEVFDLFVAMGASDKQLDFP
VVYAAARDGYAMKSLDDEKKNLEPLFETILEHVPSPSGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMK
SDGSKENGRITKLIGFLGLARTEIENAYAGDIVAIAGFNAMDVGDSVVDPVNPMPLDPMHLEEPTMSVYFAVNDSPLAGL
EGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRGELQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEH
LVIDTPQDFSGAIIERLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLTDTKGEGVMNHSFLEFRPFSGSVESR
KNGALISMENGEATAFSLFNIQERGTLFINPQTKVYVGMVIGEHSRDNDLDVNPIKSKHLTNMRASGSDDAIKLTPPRTM
VLERALEWIEEDEILEVTPLNLRIRKKILDPNMRKRAKK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=309, Percent_Identity=33.6569579288026, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=48.1203007518797, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=41.3793103448276, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=39.3103448275862, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=45.945945945946, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=45.945945945946, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=45.945945945946, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI25306283, Length=145, Percent_Identity=40.6896551724138, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI19923640, Length=145, Percent_Identity=40.6896551724138, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI25306287, Length=145, Percent_Identity=40.6896551724138, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI217272892, Length=172, Percent_Identity=35.4651162790698, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI217272894, Length=172, Percent_Identity=35.4651162790698, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI34147630, Length=274, Percent_Identity=26.6423357664234, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI53729339, Length=278, Percent_Identity=28.4172661870504, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI53729337, Length=278, Percent_Identity=28.4172661870504, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=53.3996683250415, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=299, Percent_Identity=37.123745819398, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=38.5135135135135, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790835, Length=145, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789559, Length=137, Percent_Identity=35.7664233576642, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790412, Length=294, Percent_Identity=27.2108843537415, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789737, Length=294, Percent_Identity=27.2108843537415, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17557151, Length=236, Percent_Identity=36.4406779661017, Blast_Score=145, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=45.0704225352113, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71988819, Length=134, Percent_Identity=41.7910447761194, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71988811, Length=134, Percent_Identity=41.7910447761194, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17533571, Length=146, Percent_Identity=41.7808219178082, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17506493, Length=174, Percent_Identity=35.632183908046, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=35.8208955223881, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994658, Length=259, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323320, Length=493, Percent_Identity=26.7748478701826, Blast_Score=152, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324707, Length=163, Percent_Identity=38.6503067484663, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320593, Length=163, Percent_Identity=38.6503067484663, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323098, Length=149, Percent_Identity=38.255033557047, Blast_Score=101, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324166, Length=180, Percent_Identity=35, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=151, Percent_Identity=37.7483443708609, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324761, Length=270, Percent_Identity=27.037037037037, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324550, Length=286, Percent_Identity=24.1258741258741, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI78706572, Length=493, Percent_Identity=27.5862068965517, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24582462, Length=148, Percent_Identity=41.8918918918919, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24585711, Length=166, Percent_Identity=37.9518072289157, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24585713, Length=166, Percent_Identity=37.9518072289157, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24585709, Length=166, Percent_Identity=37.9518072289157, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI28574573, Length=139, Percent_Identity=39.568345323741, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357743, Length=171, Percent_Identity=36.2573099415205, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221458488, Length=233, Percent_Identity=33.9055793991416, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI281363316, Length=231, Percent_Identity=30.7359307359307, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17864358, Length=231, Percent_Identity=30.7359307359307, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921738, Length=280, Percent_Identity=28.9285714285714, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550900, Length=324, Percent_Identity=26.2345679012346, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28572034, Length=238, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66647; Mature: 66647

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDERVMDSNDLERERGITILSKNT
CCCCCEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHCCEEEEECCE
AIYYKGTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGI
EEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCC
CPIVVVNKIDKPAAEPDRVVDEVFDLFVAMGASDKQLDFPVVYAAARDGYAMKSLDDEKK
CCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEECCCCCHHH
NLEPLFETILEHVPSPSGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMK
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEHHCCCCCCCCCEEEEE
SDGSKENGRITKLIGFLGLARTEIENAYAGDIVAIAGFNAMDVGDSVVDPVNPMPLDPMH
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHCCCCHHCCCCCCCCCCCCC
LEEPTMSVYFAVNDSPLAGLEGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRG
CCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEHHHCCCCEEEECCCC
ELQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAIIERLGKR
EEEEEEEEEHHHCCCCEEECCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
KAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLTDTKGEGVMNHSFLEFRPFSGSVESR
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
KNGALISMENGEATAFSLFNIQERGTLFINPQTKVYVGMVIGEHSRDNDLDVNPIKSKHL
CCCCEEEECCCCEEEEEEEEECCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCHHHH
TNMRASGSDDAIKLTPPRTMVLERALEWIEEDEILEVTPLNLRIRKKILDPNMRKRAKK
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCEEHHHHCCCCHHHHCCC
>Mature Secondary Structure
MKNIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDERVMDSNDLERERGITILSKNT
CCCCCEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHCCEEEEECCE
AIYYKGTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGI
EEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCC
CPIVVVNKIDKPAAEPDRVVDEVFDLFVAMGASDKQLDFPVVYAAARDGYAMKSLDDEKK
CCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCEECCCCCHHH
NLEPLFETILEHVPSPSGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMK
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEHHCCCCCCCCCEEEEE
SDGSKENGRITKLIGFLGLARTEIENAYAGDIVAIAGFNAMDVGDSVVDPVNPMPLDPMH
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHCCCCHHCCCCCCCCCCCCC
LEEPTMSVYFAVNDSPLAGLEGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRG
CCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEHHHCCCCEEEECCCC
ELQITILAENLRREGFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAIIERLGKR
EEEEEEEEEHHHCCCCEEECCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
KAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLTDTKGEGVMNHSFLEFRPFSGSVESR
HHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCC
KNGALISMENGEATAFSLFNIQERGTLFINPQTKVYVGMVIGEHSRDNDLDVNPIKSKHL
CCCCEEEECCCCEEEEEEEEECCCCEEEECCCCEEEEEEEEECCCCCCCCCCCCCCHHHH
TNMRASGSDDAIKLTPPRTMVLERALEWIEEDEILEVTPLNLRIRKKILDPNMRKRAKK
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCEEHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]