| Definition | Helicobacter pylori Shi470, complete genome. |
|---|---|
| Accession | NC_010698 |
| Length | 1,608,548 |
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The map label for this gene is vspIM [H]
Identifier: 188527264
GI number: 188527264
Start: 452573
End: 455023
Strand: Direct
Name: vspIM [H]
Synonym: HPSH_02355
Alternate gene names: 188527264
Gene position: 452573-455023 (Clockwise)
Preceding gene: 188527263
Following gene: 188527265
Centisome position: 28.14
GC content: 32.84
Gene sequence:
>2451_bases ATGCTTTCAAACGCTCTTTCTGTTGCAGAAATCGCTCGCCTAGTCAATGTTTCTCATAGCAGCGTGCATAACTGGATCAA AACCAATCTTTTAGAGAAAATAGAGATTGATTCAAAAATTTATGTGAAAACAAGCTCTTTTTTAGATTTTTGCCGCAACC ATTTAGGGAAAAACAAGCTTAACAAATACGCTAACAAATCCTTAAAAGGCGCGCATAACCATCAAGAATTGATTTTAAAA TACCTAAAAATATTAGAAAATAGTTCTGATTTAGAAAAGTTGGGTTCTTATTATGAAGAAGAGCTTTCTAACACTACCAG AAATTTAGAAGGCATTTACTACACTCCTAATAAAATAGTAGAACAACTTTTCACTCTCCCTAAAGATTTTGATGCTTCTC AAGCGATTTTTTGCGATCCGGCTGTGGGGAGCGGGAATTTCATCATGCATGCTTTAAAGCTGGGGTTTAAGGTTGAAAAT ATTTATGGCTATGATACGGACGCTTTTGCTATCGCTTTGACTAAAAAGCGTATTAAAGAGCGTTATCATTTGGATTGCCC TAATATTGTGCAAAAAGATTTTTTAAATTTAAAACACACCCCACAATTTGATTGCATTTTCACTAACCCGCCATGGGGTA AGAAATACAATCAAAACCAAAAAGAAAATTTCAAACAGTGCTTTAACCTCTCTCAAAGCCTAGATAGCGCGTCGCTCTTT TTTATAGCGAGTTTGAATTGCTTAAAAGAAAACGCTCATTTGGGGCTATTATTACCCGAAAGTTGTTTGAATATTGATGC GTTTAGTAAAATGCGAGAAATGGCTCTGAAGTTTCAAATTAGAAGCCTTATTGATTTCAACAAACCCTTTAAAACCCTAA TGACTAAGGCTGTTGGTTTGGCGCTTAAAAAAGCCCCTAACAAGAATCAAAAAATCTCATGCTTTTATCAAAGTAGTGAG TTCAAACGCTCGCCCTCTTCTTTTTTAAACAACCCTAAAAAGATTTTTAATATCCATTGCTCTAGCAAAGAAAATAAAAT TTTAGACCACCTTTTTTCCCTTCCTCATATAACTTTAAAAAATAACGCTCATTTTGCTTTAGGGATTGTTACAGGCAACA ATAAAGAAAAATTACACTCCAAACAAGAAAAAAATACCATTCCTATTTTTAGGGGTTCAGATATTTTAAAAGACAGATTA AAAGCCCCTAGCCAATTCATTAACGCTGATCTAAAAGACTGCCAGCAAGTCGCTCCCTTAAGCCTTTATCAGTCTAGAGA AAAAATCGTGTATAAATTCATTTCTTCAAAACTTGTCTTTTTTTATGATAATAAGCAACGCCTTTTTTTAAATAGCGCGA ACATGTTTGTTTTAAAAGAAAATTTTCCTATCAACGCTAATGCGCTAAAAGAATTATTAAACAGCGATTTAATGCAATTT ATTTTTGAATCGCTTTTTAAAACGCATAAAATTTTAAGAAAAGATTTGGAATGCTTGCCCCTATTTGTGCAATTTATCAA CAATAGTTTTGATGAAAAATTTTATTTGAAAAATTTAGGGATAGAAAAAAAGACCCTAAACATTTTACAATCAGGAAAAA CCATGCACATCGCTTGTCTTTTGGCTTTAGGGGATAACCTCATCACGCTTAGCCTTTTAAAAGAAATCGCTTCCAAACAG CAACAACCCCTTAAAATCCTAGGCACTCATTTGACTTTAAAAATCGCCAGGCTTTTAGAATGCGAAAAACATTTTGAAAT CATCCCTCTTTTTGAAAATGTCCCTGCTTTTTATGACCTTAAAAAACAAGGAGTTTTTTGGGCGATGAAGGATTTTTTAT TGTTGTTAAAAGCGATTAAAAAGCATCAAATCAAACATTTGATTTTAGAAAAACAGGATTTTAGAAGCGCTCTTTTAACC ACATTCATTCCCATAACCGCTCCTAATAAAGACATTAAAAATGTTTATCAAAACCGCCAGGAGTTGTTTTCTCAAATTTA TGGGCATGTTTTTAATCATTCTCCATATCTTATGAATTTAAAAAACCCCAAAAAGATTTTAATCAACCCTTTCACAAGAT CAATAGAGCGAAGTATCCCTTTAGAGCATTTGCAAATCGTTTTAAAACTCTTAAAACCCTTTTGTGTTACGCTTTTAGAT TTTGAAGAACGATACGCTTTTTTAAAAGATAGAGTTACTCATTATCGCGTTAAAACCAGTTTAGAAGAAGTTAAAAACCT GATTTTAGAAAGCGATTTGTATATAGGGGGGGATTCGTTTTTGATCCATTTGGCTTACTATTTAAAGAAAAATTATTTTA TCTTTTTTTATAGGGATAATGACGATTTCATGCCGCCTAATGGTAAGAATGAAAATTTTCTAAAAGCCCACAAAAGCCAT TTTATAGAACAGGATTTAGCCAAAAAATTCCGCCATTTGGGGCTATTATAA
Upstream 100 bases:
>100_bases CCTTTTATGAAACGCATGGCAAAGGGTTAAACACTTCCCTCTTTTTCAAACGCCTTGTGGTGTTTAATGTGAGTTATGTT TATAGTTTTTAGGGGGTAAA
Downstream 100 bases:
>100_bases TATTGTGTTATACTTCTAAATTCAATTTTGCTTGTTAGGACACTTATGAAAAATATTAGAAATATCGCTGTAATCGCGCA TGTTGATCATGGGAAAACCA
Product: type II adenine specific methyltransferase
Products: NA
Alternate protein names: M.VspI; Adenine-specific methyltransferase VspI [H]
Number of amino acids: Translated: 816; Mature: 816
Protein sequence:
>816_residues MLSNALSVAEIARLVNVSHSSVHNWIKTNLLEKIEIDSKIYVKTSSFLDFCRNHLGKNKLNKYANKSLKGAHNHQELILK YLKILENSSDLEKLGSYYEEELSNTTRNLEGIYYTPNKIVEQLFTLPKDFDASQAIFCDPAVGSGNFIMHALKLGFKVEN IYGYDTDAFAIALTKKRIKERYHLDCPNIVQKDFLNLKHTPQFDCIFTNPPWGKKYNQNQKENFKQCFNLSQSLDSASLF FIASLNCLKENAHLGLLLPESCLNIDAFSKMREMALKFQIRSLIDFNKPFKTLMTKAVGLALKKAPNKNQKISCFYQSSE FKRSPSSFLNNPKKIFNIHCSSKENKILDHLFSLPHITLKNNAHFALGIVTGNNKEKLHSKQEKNTIPIFRGSDILKDRL KAPSQFINADLKDCQQVAPLSLYQSREKIVYKFISSKLVFFYDNKQRLFLNSANMFVLKENFPINANALKELLNSDLMQF IFESLFKTHKILRKDLECLPLFVQFINNSFDEKFYLKNLGIEKKTLNILQSGKTMHIACLLALGDNLITLSLLKEIASKQ QQPLKILGTHLTLKIARLLECEKHFEIIPLFENVPAFYDLKKQGVFWAMKDFLLLLKAIKKHQIKHLILEKQDFRSALLT TFIPITAPNKDIKNVYQNRQELFSQIYGHVFNHSPYLMNLKNPKKILINPFTRSIERSIPLEHLQIVLKLLKPFCVTLLD FEERYAFLKDRVTHYRVKTSLEEVKNLILESDLYIGGDSFLIHLAYYLKKNYFIFFYRDNDDFMPPNGKNENFLKAHKSH FIEQDLAKKFRHLGLL
Sequences:
>Translated_816_residues MLSNALSVAEIARLVNVSHSSVHNWIKTNLLEKIEIDSKIYVKTSSFLDFCRNHLGKNKLNKYANKSLKGAHNHQELILK YLKILENSSDLEKLGSYYEEELSNTTRNLEGIYYTPNKIVEQLFTLPKDFDASQAIFCDPAVGSGNFIMHALKLGFKVEN IYGYDTDAFAIALTKKRIKERYHLDCPNIVQKDFLNLKHTPQFDCIFTNPPWGKKYNQNQKENFKQCFNLSQSLDSASLF FIASLNCLKENAHLGLLLPESCLNIDAFSKMREMALKFQIRSLIDFNKPFKTLMTKAVGLALKKAPNKNQKISCFYQSSE FKRSPSSFLNNPKKIFNIHCSSKENKILDHLFSLPHITLKNNAHFALGIVTGNNKEKLHSKQEKNTIPIFRGSDILKDRL KAPSQFINADLKDCQQVAPLSLYQSREKIVYKFISSKLVFFYDNKQRLFLNSANMFVLKENFPINANALKELLNSDLMQF IFESLFKTHKILRKDLECLPLFVQFINNSFDEKFYLKNLGIEKKTLNILQSGKTMHIACLLALGDNLITLSLLKEIASKQ QQPLKILGTHLTLKIARLLECEKHFEIIPLFENVPAFYDLKKQGVFWAMKDFLLLLKAIKKHQIKHLILEKQDFRSALLT TFIPITAPNKDIKNVYQNRQELFSQIYGHVFNHSPYLMNLKNPKKILINPFTRSIERSIPLEHLQIVLKLLKPFCVTLLD FEERYAFLKDRVTHYRVKTSLEEVKNLILESDLYIGGDSFLIHLAYYLKKNYFIFFYRDNDDFMPPNGKNENFLKAHKSH FIEQDLAKKFRHLGLL >Mature_816_residues MLSNALSVAEIARLVNVSHSSVHNWIKTNLLEKIEIDSKIYVKTSSFLDFCRNHLGKNKLNKYANKSLKGAHNHQELILK YLKILENSSDLEKLGSYYEEELSNTTRNLEGIYYTPNKIVEQLFTLPKDFDASQAIFCDPAVGSGNFIMHALKLGFKVEN IYGYDTDAFAIALTKKRIKERYHLDCPNIVQKDFLNLKHTPQFDCIFTNPPWGKKYNQNQKENFKQCFNLSQSLDSASLF FIASLNCLKENAHLGLLLPESCLNIDAFSKMREMALKFQIRSLIDFNKPFKTLMTKAVGLALKKAPNKNQKISCFYQSSE FKRSPSSFLNNPKKIFNIHCSSKENKILDHLFSLPHITLKNNAHFALGIVTGNNKEKLHSKQEKNTIPIFRGSDILKDRL KAPSQFINADLKDCQQVAPLSLYQSREKIVYKFISSKLVFFYDNKQRLFLNSANMFVLKENFPINANALKELLNSDLMQF IFESLFKTHKILRKDLECLPLFVQFINNSFDEKFYLKNLGIEKKTLNILQSGKTMHIACLLALGDNLITLSLLKEIASKQ QQPLKILGTHLTLKIARLLECEKHFEIIPLFENVPAFYDLKKQGVFWAMKDFLLLLKAIKKHQIKHLILEKQDFRSALLT TFIPITAPNKDIKNVYQNRQELFSQIYGHVFNHSPYLMNLKNPKKILINPFTRSIERSIPLEHLQIVLKLLKPFCVTLLD FEERYAFLKDRVTHYRVKTSLEEVKNLILESDLYIGGDSFLIHLAYYLKKNYFIFFYRDNDDFMPPNGKNENFLKAHKSH FIEQDLAKKFRHLGLL
Specific function: This methylase recognizes the double-stranded sequence ATTAAT, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the VspI endonuclease [H]
COG id: COG0827
COG function: function code L; Adenine-specific DNA methylase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003356 - InterPro: IPR002052 - InterPro: IPR002296 [H]
Pfam domain/function: PF02384 N6_Mtase [H]
EC number: =2.1.1.72 [H]
Molecular weight: Translated: 94738; Mature: 94738
Theoretical pI: Translated: 9.89; Mature: 9.89
Prosite motif: PS00092 N6_MTASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLSNALSVAEIARLVNVSHSSVHNWIKTNLLEKIEIDSKIYVKTSSFLDFCRNHLGKNKL CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCHHHH NKYANKSLKGAHNHQELILKYLKILENSSDLEKLGSYYEEELSNTTRNLEGIYYTPNKIV HHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECHHHHH EQLFTLPKDFDASQAIFCDPAVGSGNFIMHALKLGFKVENIYGYDTDAFAIALTKKRIKE HHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHH RYHLDCPNIVQKDFLNLKHTPQFDCIFTNPPWGKKYNQNQKENFKQCFNLSQSLDSASLF HHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHH FIASLNCLKENAHLGLLLPESCLNIDAFSKMREMALKFQIRSLIDFNKPFKTLMTKAVGL HHHHHHHHHCCCCEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH ALKKAPNKNQKISCFYQSSEFKRSPSSFLNNPKKIFNIHCSSKENKILDHLFSLPHITLK HHHCCCCCCCEEEEEEECCHHCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCEEEE NNAHFALGIVTGNNKEKLHSKQEKNTIPIFRGSDILKDRLKAPSQFINADLKDCQQVAPL CCCEEEEEEEECCCHHHHHHHHHCCCCCEECCCHHHHHHHCCCHHHHCCCHHHHHHHCCH SLYQSREKIVYKFISSKLVFFYDNKQRLFLNSANMFVLKENFPINANALKELLNSDLMQF HHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHH IFESLFKTHKILRKDLECLPLFVQFINNSFDEKFYLKNLGIEKKTLNILQSGKTMHIACL HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHCCCEEEEEEH LALGDNLITLSLLKEIASKQQQPLKILGTHLTLKIARLLECEKHFEIIPLFENVPAFYDL HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHCCCHHHHH KKQGVFWAMKDFLLLLKAIKKHQIKHLILEKQDFRSALLTTFIPITAPNKDIKNVYQNRQ HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH ELFSQIYGHVFNHSPYLMNLKNPKKILINPFTRSIERSIPLEHLQIVLKLLKPFCVTLLD HHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH FEERYAFLKDRVTHYRVKTSLEEVKNLILESDLYIGGDSFLIHLAYYLKKNYFIFFYRDN HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHCCEEEEEEECC DDFMPPNGKNENFLKAHKSHFIEQDLAKKFRHLGLL CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MLSNALSVAEIARLVNVSHSSVHNWIKTNLLEKIEIDSKIYVKTSSFLDFCRNHLGKNKL CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCHHHH NKYANKSLKGAHNHQELILKYLKILENSSDLEKLGSYYEEELSNTTRNLEGIYYTPNKIV HHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEECHHHHH EQLFTLPKDFDASQAIFCDPAVGSGNFIMHALKLGFKVENIYGYDTDAFAIALTKKRIKE HHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHH RYHLDCPNIVQKDFLNLKHTPQFDCIFTNPPWGKKYNQNQKENFKQCFNLSQSLDSASLF HHCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHH FIASLNCLKENAHLGLLLPESCLNIDAFSKMREMALKFQIRSLIDFNKPFKTLMTKAVGL HHHHHHHHHCCCCEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH ALKKAPNKNQKISCFYQSSEFKRSPSSFLNNPKKIFNIHCSSKENKILDHLFSLPHITLK HHHCCCCCCCEEEEEEECCHHCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCEEEE NNAHFALGIVTGNNKEKLHSKQEKNTIPIFRGSDILKDRLKAPSQFINADLKDCQQVAPL CCCEEEEEEEECCCHHHHHHHHHCCCCCEECCCHHHHHHHCCCHHHHCCCHHHHHHHCCH SLYQSREKIVYKFISSKLVFFYDNKQRLFLNSANMFVLKENFPINANALKELLNSDLMQF HHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHH IFESLFKTHKILRKDLECLPLFVQFINNSFDEKFYLKNLGIEKKTLNILQSGKTMHIACL HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHCCCEEEEEEH LALGDNLITLSLLKEIASKQQQPLKILGTHLTLKIARLLECEKHFEIIPLFENVPAFYDL HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEHHHCCCHHHHH KKQGVFWAMKDFLLLLKAIKKHQIKHLILEKQDFRSALLTTFIPITAPNKDIKNVYQNRQ HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH ELFSQIYGHVFNHSPYLMNLKNPKKILINPFTRSIERSIPLEHLQIVLKLLKPFCVTLLD HHHHHHHHHHHCCCCEEEECCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH FEERYAFLKDRVTHYRVKTSLEEVKNLILESDLYIGGDSFLIHLAYYLKKNYFIFFYRDN HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHCCEEEEEEECC DDFMPPNGKNENFLKAHKSHFIEQDLAKKFRHLGLL CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8493116; 7607528 [H]