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The map label for this gene is nixA [H]

Identifier: 188527179

GI number: 188527179

Start: 369752

End: 370741

Strand: Direct

Name: nixA [H]

Synonym: HPSH_01930

Alternate gene names: 188527179

Gene position: 369752-370741 (Clockwise)

Preceding gene: 188527178

Following gene: 188527181

Centisome position: 22.99

GC content: 42.02

Gene sequence:

>990_bases
TTGTGGTTTCCTTATTTTTTAGCGATTGTGTTCTTGCATGCATTAGGTTTAGCGTTGCTCTTTATGGCCAATAACGCTTC
GTTTTATGCGGCGGCGTCTATGGCTTACATGCTAGGGGCAAAGCATGCCTTTGATGCAGATCACATCGCTTGCATAGACA
ACACTATTAGAAAGCTCACCCAACAAGGCAAAAACGCCTATGGTGTGGGGTTTTACTTTTCTATGGGGCATTCAAGCGTG
GTGATTTTAATGACCATCATCAGCGCGTTTGCGATCGCTTGGGCTAAAGAGCATACGCCGATGTTAGAAGAAATAGGGGG
GGTAGTGGGGACTTTAGTTTCTGGGCTTTTTTTGCTCATTATAGGGCTATTGAATGCCATTATTCTAGTGGATTTACTAA
AAATATTCAAAAAATCGCATTCTAATGAAAGCCTAAGCCAGCAGCAAAATGAAGAGATCGAGCGGCTCTTAACGAGTAGG
GGCTTACTCAACCGCTTTTTTAAGCCCTTGTTTAATTTCATCTCCAAGTCGTGGCATATTTATCCTATCGGTTTTCTTTT
TGGGTTGGGTTTTGATACCGCTAGTGAAATCGCGCTTTTGGCCCTCTCTAGCAGCGCGATTAAAGTGAGTGTGGTGGGCA
TGCTCTCTTTACCCATTCTTTTTGCCGCTGGCATGAGTTTGTTTGACACTTTAGATGGGGCGTTCATGCTTAAGGCGTAT
GACTGGGCGTTCAAAACCCCTTTAAGAAAAATCTATTACAATATCTCTATCACGGCCTTAAGCGTGTTTATCGCGCTCTT
TATCGGCTTGATTGAGCTTTTTCAAGTCGTTAGCGAGAAACTCCACTTAAAATTTGAAAACCGCCTTTTAAACGCCTTAC
AAAGCCTAGAATTTACAGATTTGGGCTATTACTTGGTGGGCTTATTTGTAATAGCGTTTTTAGGCTCATTCTTTTTATGG
AAAATCAAGTTTTCTAAACTAGAGAGCTGA

Upstream 100 bases:

>100_bases
CAGAAAATAATCAAAAATAAATCCTAAAGTTTTCTAATTTAACAAAATATATTACAATTACCCAAAAAGTATTATTTTTC
TTAAAAGGTGCACTGTGAAA

Downstream 100 bases:

>100_bases
ATTTTAAGCCCTCAAATTATCGCTTAACAAATCTTTAAGGCTTTTATTTGAAAAACTTGGCATAAAGGCTTTAGGGTTTG
AAAGGCTTTCGCTCAAATAA

Product: high affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHSSV
VILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILVDLLKIFKKSHSNESLSQQQNEEIERLLTSR
GLLNRFFKPLFNFISKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAY
DWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLNALQSLEFTDLGYYLVGLFVIAFLGSFFLW
KIKFSKLES

Sequences:

>Translated_329_residues
MWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHSSV
VILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILVDLLKIFKKSHSNESLSQQQNEEIERLLTSR
GLLNRFFKPLFNFISKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAY
DWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLNALQSLEFTDLGYYLVGLFVIAFLGSFFLW
KIKFSKLES
>Mature_329_residues
MWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLTQQGKNAYGVGFYFSMGHSSV
VILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLIIGLLNAIILVDLLKIFKKSHSNESLSQQQNEEIERLLTSR
GLLNRFFKPLFNFISKSWHIYPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAY
DWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLNALQSLEFTDLGYYLVGLFVIAFLGSFFLW
KIKFSKLES

Specific function: High-affinity nickel intake protein. Imports nickel ions in an energy-dependent fashion. Necessary for the expression of catalytically active urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 36719; Mature: 36719

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLT
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
QQGKNAYGVGFYFSMGHSSVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLI
HCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IGLLNAIILVDLLKIFKKSHSNESLSQQQNEEIERLLTSRGLLNRFFKPLFNFISKSWHI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
YPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAY
EEHHHHHHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLNALQSLEFTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LGYYLVGLFVIAFLGSFFLWKIKFSKLES
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWFPYFLAIVFLHALGLALLFMANNASFYAAASMAYMLGAKHAFDADHIACIDNTIRKLT
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
QQGKNAYGVGFYFSMGHSSVVILMTIISAFAIAWAKEHTPMLEEIGGVVGTLVSGLFLLI
HCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
IGLLNAIILVDLLKIFKKSHSNESLSQQQNEEIERLLTSRGLLNRFFKPLFNFISKSWHI
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
YPIGFLFGLGFDTASEIALLALSSSAIKVSVVGMLSLPILFAAGMSLFDTLDGAFMLKAY
EEHHHHHHCCCCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DWAFKTPLRKIYYNISITALSVFIALFIGLIELFQVVSEKLHLKFENRLLNALQSLEFTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LGYYLVGLFVIAFLGSFFLWKIKFSKLES
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]