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The map label for this gene is rfaC [H]

Identifier: 188527085

GI number: 188527085

Start: 271695

End: 272705

Strand: Direct

Name: rfaC [H]

Synonym: HPSH_01450

Alternate gene names: 188527085

Gene position: 271695-272705 (Clockwise)

Preceding gene: 188527084

Following gene: 188527086

Centisome position: 16.89

GC content: 37.78

Gene sequence:

>1011_bases
TTGAAGATAGCAATTGTCAGGCTTTCAGCGCTCGGGGATATTATCGTGAGTGCGGTGTTTTTAGCGCTGATTAAAGAGCG
TTTTACTAACGCTCAAATAGAATGGTTCGTGGATGAGAGATTCAGTGCGATTTTAGAGCATTCCCCTTATATTGATAAAT
TACACCCCATCGCTTTAAAAAGCGCGTTCACGACCTTTAACCCTTTGAAGATTTTCAAACTTTTTAAATCTTTAAGGGCT
TATGAATACGATATAGTCATTGACATGCAAGGCTTGATCAAATCCGCTCTCATCACTCAAATGTTAAAAGCCCCTAAAAA
AGTCGGCTTTGATTGCGCTTCGGCTAGGGAGGGTTTGAGCGCGTTTTTTTACTCGCAAAAAGTTTCTATCGCTTATAATG
AGTCTGTTTTAAAGCGCAATTTCACGCTCCTTTCTCATGCCCTAAACTTGCCCAAAAAAGAAATTTCAGAGGGCTTAAGC
TCTAGATCTAAAGTGTTTTCTTACCAAGATTCTCCAAAAATTGATGCGTTAAATTTGAATGAAAACAAGCTAAAAATCCT
TTTTGTTTTAGAAACTTCTAAAATCAATAAAACTTACCCCATAGAGCGTTTTAAAGAGCTGGCTTTGATGCTAGAAAATT
TTCAAATTTGCTTGCTATGGCATGCTGATGAAGATAAGGTTAATGTGCTTTATGGCGCTTTAAAAAACCAGTGCGATGTG
TTATTGCTCCCCAAACTCACTTTAAACGAGGTTAAGGCGTTGCTCTTTAAAATGGATTTGATTATTGGGGGCGATACGGG
TATTACGCATTTAGCATGGGCGTTGCAAAAACCCAGCATCACCCTTTATGGCAACACGCCCATGGAGCGTTTTAAATTAG
AAAGCCCGATCAATGTTTCGCTCACCGGTAATTCAAACGCCAACTACCATAAAAAGGATTTTTCTATCCAAAACATAGAT
CCTAAAAAAATTAAAGAATGCGTTTTAAACATTTTAAAGGAAAAAGAATGA

Upstream 100 bases:

>100_bases
AAAAAAACAAGCTTGTGATCCATTCTAATGATGCGCTTTACTTGGCTAAAGAGATGCTCCCTAAACTCGTTAAGCCTATT
CCTTTGATGATAGAGTTTGC

Downstream 100 bases:

>100_bases
CTTATAAAGAACGACTCATACACGAAAAAATATTGAACCAAGACGATAAGGGTTTTAAAACAGAACTGCACATTTTGAGT
ATTTTTATCGTGGAATCTTT

Product: lipopolysaccharide heptosyltransferase-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKIAIVRLSALGDIIVSAVFLALIKERFTNAQIEWFVDERFSAILEHSPYIDKLHPIALKSAFTTFNPLKIFKLFKSLRA
YEYDIVIDMQGLIKSALITQMLKAPKKVGFDCASAREGLSAFFYSQKVSIAYNESVLKRNFTLLSHALNLPKKEISEGLS
SRSKVFSYQDSPKIDALNLNENKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKVNVLYGALKNQCDV
LLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESPINVSLTGNSNANYHKKDFSIQNID
PKKIKECVLNILKEKE

Sequences:

>Translated_336_residues
MKIAIVRLSALGDIIVSAVFLALIKERFTNAQIEWFVDERFSAILEHSPYIDKLHPIALKSAFTTFNPLKIFKLFKSLRA
YEYDIVIDMQGLIKSALITQMLKAPKKVGFDCASAREGLSAFFYSQKVSIAYNESVLKRNFTLLSHALNLPKKEISEGLS
SRSKVFSYQDSPKIDALNLNENKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKVNVLYGALKNQCDV
LLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESPINVSLTGNSNANYHKKDFSIQNID
PKKIKECVLNILKEKE
>Mature_336_residues
MKIAIVRLSALGDIIVSAVFLALIKERFTNAQIEWFVDERFSAILEHSPYIDKLHPIALKSAFTTFNPLKIFKLFKSLRA
YEYDIVIDMQGLIKSALITQMLKAPKKVGFDCASAREGLSAFFYSQKVSIAYNESVLKRNFTLLSHALNLPKKEISEGLS
SRSKVFSYQDSPKIDALNLNENKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKVNVLYGALKNQCDV
LLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESPINVSLTGNSNANYHKKDFSIQNID
PKKIKECVLNILKEKE

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=294, Percent_Identity=28.9115646258503, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790062, Length=281, Percent_Identity=23.4875444839858, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.4.1.-

Molecular weight: Translated: 38210; Mature: 38210

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIVRLSALGDIIVSAVFLALIKERFTNAQIEWFVDERFSAILEHSPYIDKLHPIALK
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCHHHCCHHHHH
SAFTTFNPLKIFKLFKSLRAYEYDIVIDMQGLIKSALITQMLKAPKKVGFDCASAREGLS
HHHCCCCHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AFFYSQKVSIAYNESVLKRNFTLLSHALNLPKKEISEGLSSRSKVFSYQDSPKIDALNLN
HHHHHCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCCEEEEECC
ENKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKVNVLYGALKNQCDV
CCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCE
LLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESPINVS
EEECCCCHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCCEEEEECCCHHHHCCCCCCEEE
LTGNSNANYHKKDFSIQNIDPKKIKECVLNILKEKE
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIAIVRLSALGDIIVSAVFLALIKERFTNAQIEWFVDERFSAILEHSPYIDKLHPIALK
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCHHHCCHHHHH
SAFTTFNPLKIFKLFKSLRAYEYDIVIDMQGLIKSALITQMLKAPKKVGFDCASAREGLS
HHHCCCCHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AFFYSQKVSIAYNESVLKRNFTLLSHALNLPKKEISEGLSSRSKVFSYQDSPKIDALNLN
HHHHHCEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCCCCEEEEECC
ENKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKVNVLYGALKNQCDV
CCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCCE
LLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESPINVS
EEECCCCHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCCEEEEECCCHHHHCCCCCCEEE
LTGNSNANYHKKDFSIQNIDPKKIKECVLNILKEKE
EECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1527014; 11677609; 1657881 [H]