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The map label for this gene is nifU [H]

Identifier: 188527026

GI number: 188527026

Start: 214471

End: 215451

Strand: Direct

Name: nifU [H]

Synonym: HPSH_01145

Alternate gene names: 188527026

Gene position: 214471-215451 (Clockwise)

Preceding gene: 188527025

Following gene: 188527027

Centisome position: 13.33

GC content: 44.34

Gene sequence:

>981_bases
ATGGCAAAACATGATTTAGTGGGATCAGCCCTTTGGGACGCGTATTCTAAAGAAGTTCAAAGGCGCATGGATAACCCTAC
GCATTTAGGGGTCATCACCGAAGAGCAGGCTAAGGCTAAAAACGCTAAGCTCATTGTAGCGGATTATGGTGCAGAAGCAT
GCGGTGATGCGGTGAGGTTGTATTGGCTTGTAGATGAAAGCACGGATAAGATTGTTGATGCGAAGTTTAAAAGCTTTGGT
TGCGGGACAGCGATCGCAAGCTCAGACATGATGGTGGAATTGTGTTTGAACAAAAGAGTCCAAGAGGCGGTAAAAATCAC
GAATTTAGATGTGGAAAGAGGCTTGAGAGATGAACCGGACACGCCGGCTGTCCCTGGGCAAAAAATGCACTGCTCCGTGA
TGGCGTATGATGTGATCAAAAAAGCTGCCGGCATGTATTTGGGGAAAAACGCTGAAGATTTTGAAGAAGAAATCATCGTG
TGCGAGTGCGCTAGGGTGAGTTTAGGCACGATTAAAGAAGTGATTAGGCTCAATGATTTAAAAAGCGTTGAAGAAATCAC
TAACTACACCAAAGCCGGCGCTTTTTGTAAAAGCTGTGTGAGGCCTGGAGGGCATGAAAAAAGGGATTATTACCTGGTGG
ATATTCTTAAAGAAGTGCGCGAAGAAATGGAAGCTGAAAAACTTAAAGCCACCGCTAATAAATCTCAAAGCGGGGAATTG
GCTTTCAGGGAAATGACTATGGTTCAAAAGATTAAAGCCGTGGATAAAGTCATTGATGAAAATATCCGCCCGATGCTTAT
GATGGATGGAGGGGATTTAGAGATTTTAGACATTAAAGAAAGCGATGATTACATTGATGTGTATATCCGCTACATGGGGG
CATGCGATGGGTGCATGAGCGCGGCTACTGGGACTTTATTTGCCATTGAAAACGCCTTACAGGAATTATTGGATCGCAGT
ATCAGGGTGTTACCGATTTGA

Upstream 100 bases:

>100_bases
GGAAGCTGAAATTGATAAAACGATTGAAGTTTTCTCTCAAGCGGCTACAAGGTTGAGAAACATTTCAAGTTCTTATTAAA
AAGGATATAAAGGAATCAAA

Downstream 100 bases:

>100_bases
TTTGTTTTGAACTTTTTAGGGGGTGGAGGTTAGGGGGTGGAGGCCTTTTTTAAGCGAAGCGCTAATAAACTCACAATGAG
GAATGATTAGCGCTTGCAAC

Product: nifU-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAKHDLVGSALWDAYSKEVQRRMDNPTHLGVITEEQAKAKNAKLIVADYGAEACGDAVRLYWLVDESTDKIVDAKFKSFG
CGTAIASSDMMVELCLNKRVQEAVKITNLDVERGLRDEPDTPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIV
CECARVSLGTIKEVIRLNDLKSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKATANKSQSGEL
AFREMTMVQKIKAVDKVIDENIRPMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMSAATGTLFAIENALQELLDRS
IRVLPI

Sequences:

>Translated_326_residues
MAKHDLVGSALWDAYSKEVQRRMDNPTHLGVITEEQAKAKNAKLIVADYGAEACGDAVRLYWLVDESTDKIVDAKFKSFG
CGTAIASSDMMVELCLNKRVQEAVKITNLDVERGLRDEPDTPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIV
CECARVSLGTIKEVIRLNDLKSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKATANKSQSGEL
AFREMTMVQKIKAVDKVIDENIRPMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMSAATGTLFAIENALQELLDRS
IRVLPI
>Mature_325_residues
AKHDLVGSALWDAYSKEVQRRMDNPTHLGVITEEQAKAKNAKLIVADYGAEACGDAVRLYWLVDESTDKIVDAKFKSFGC
GTAIASSDMMVELCLNKRVQEAVKITNLDVERGLRDEPDTPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIVC
ECARVSLGTIKEVIRLNDLKSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKATANKSQSGELA
FREMTMVQKIKAVDKVIDENIRPMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMSAATGTLFAIENALQELLDRSI
RVLPI

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=138, Percent_Identity=40.5797101449275, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI24307953, Length=131, Percent_Identity=40.4580152671756, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1788878, Length=136, Percent_Identity=35.2941176470588, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17543474, Length=138, Percent_Identity=35.5072463768116, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325122, Length=100, Percent_Identity=45, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324800, Length=141, Percent_Identity=36.1702127659575, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21355597, Length=132, Percent_Identity=40.1515151515151, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR016217
- InterPro:   IPR010238
- InterPro:   IPR001075
- InterPro:   IPR002871
- ProDom:   PD002830 [H]

Pfam domain/function: PF04324 Fer2_BFD; PF01106 NifU; PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 36320; Mature: 36189

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHDLVGSALWDAYSKEVQRRMDNPTHLGVITEEQAKAKNAKLIVADYGAEACGDAVRL
CCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCCCEEEEEECCCHHCCCEEEE
YWLVDESTDKIVDAKFKSFGCGTAIASSDMMVELCLNKRVQEAVKITNLDVERGLRDEPD
EEEEECCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
TPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIVCECARVSLGTIKEVIRLNDL
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEHHHHCCHHHHHHHHHHHHH
KSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKATANKSQSGEL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AFREMTMVQKIKAVDKVIDENIRPMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMS
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
AATGTLFAIENALQELLDRSIRVLPI
HHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure 
AKHDLVGSALWDAYSKEVQRRMDNPTHLGVITEEQAKAKNAKLIVADYGAEACGDAVRL
CCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHCCCCEEEEEECCCHHCCCEEEE
YWLVDESTDKIVDAKFKSFGCGTAIASSDMMVELCLNKRVQEAVKITNLDVERGLRDEPD
EEEEECCCCHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCC
TPAVPGQKMHCSVMAYDVIKKAAGMYLGKNAEDFEEEIIVCECARVSLGTIKEVIRLNDL
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEHHHHCCHHHHHHHHHHHHH
KSVEEITNYTKAGAFCKSCVRPGGHEKRDYYLVDILKEVREEMEAEKLKATANKSQSGEL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AFREMTMVQKIKAVDKVIDENIRPMLMMDGGDLEILDIKESDDYIDVYIRYMGACDGCMS
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
AATGTLFAIENALQELLDRSIRVLPI
HHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496536 [H]