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The map label for this gene is treP [H]

Identifier: 187935414

GI number: 187935414

Start: 1905476

End: 1906882

Strand: Reverse

Name: treP [H]

Synonym: CLL_A1821

Alternate gene names: 187935414

Gene position: 1906882-1905476 (Counterclockwise)

Preceding gene: 187934239

Following gene: 187934406

Centisome position: 50.18

GC content: 32.05

Gene sequence:

>1407_bases
ATGTCTAAGTATAGTAAGGAAGTTAAAGAATTATTAGAATACATTGGTGGAGAAGAAAATGTAAATGCTGTATCACATTG
TGCAACAAGAATGAGATTTGTTTTAAATGATACATCTATTGCAGATGAAGAAAAAATTAAAAAAATTAAATTTGTTAAGG
GTACATTTACTCAAGCTGGGCAATTTCAAGTCATTATTGGAAACGATGTAGCGGAATTTTACAATGAGTTTACTGCATTA
GCTGGAATTGATGGAGTAAGTAAAGATAATTTAAAAAGTTCAGCTAAATCAAATATGAATATTGTTCAAAGAATGATGGC
TAATATAGCAGAAATATTTTCACCTTTAATACCTGCAATTATAGTAGGAGGTCTTATACTTGGTTTTAGAAATATCATAG
GTGATATTAAGATGTTTGAAAATGGTACAAAAACTCTTATTGAAATATCACAATTTTGGGCAGGAACACATAGCTTTTTG
TGGCTAATAGGTGAAGCGATATTCCATTTCTTACCTGTTGGAATCACATGGACTGTAACTAAAAAAATGGGGACAACTCA
AATACTTGGTATAGTACTTGGTATTACATTGGTCTCTCCTCAACTTTTAAATGCATATTCTGTAGCTACAGCAGAGTCAA
TTCCATTTTGGGATTTTGGCTTTACAAAAATCAATATGATAGGTTATCAATCACAAGTTATACCTGCTATTTTAGCTGGT
TTTGTACTAGTATATCTTGAAAAAGGGGTTAGAAAAATAGTTCCTTCTTCAATTTCAATGATATTTGTACCATTTTTTGC
ATTAGTGCCTACTGTTTTAATAGCACATACTGTTCTTGGTCCTATAGGTTGGGTAATTGGTTCTTGGGTTTCAGCAGTAG
TTTATGGCGGATTAACTTCAGCATTTGGAAGTATATTTGCTGCAATCTTTGGATTCCTTTATGCACCACTTGTTATAACT
GGATTACATCATATGACTAATGCAATAGACTTACAATTAATGGCTGAATTTAATGGTACAGCTTTATGGCCAATGATAGC
TTTATCAAATATAGCTCAAGGGTCAGCTGTTTTAGCTATAATTTATCTTCAAAGAAAGAATGAAGAAGAAAAACAAATAG
CAATTCCAGCATGTATATCAGCTTACCTTGGAGTAACTGAACCAGCATTATTTGGCATAAATATAAAATATAGATTCCCA
TTTGTGTGCGGAATGGTAGGATCAGCTATAGCTGCTATAATATCTGTTTCAACAGGTGTAATGGCAAATTCTGTAGGGAT
TGGTGGATTGCCTGGTATATTATCAATTAAACCACAACACATGCTTATGTTTGCAATAGCAATGGTTGCTGCTATAGTAG
TACCATTTATGCTAACTTTAATAATTGGAAAGAAAAAATTAGTATAA

Upstream 100 bases:

>100_bases
AATAAAAAACTTTCAATGTAAACATTGACAAAACATATACGTATAAGTTATTATTTAAATATAACATGTACGTATATGTT
TTAAGAGGGAGGGAAAAATA

Downstream 100 bases:

>100_bases
AATAAATAATAATTTTAAATTGGAGGACTTAGCAGTATGAAAGACTTTAAAAAAAGTACTGTTTATCAAATATATCCTAA
ATCATTTAATGATTCAAATG

Product: pts system, trehalose-specific iibc component

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MSKYSKEVKELLEYIGGEENVNAVSHCATRMRFVLNDTSIADEEKIKKIKFVKGTFTQAGQFQVIIGNDVAEFYNEFTAL
AGIDGVSKDNLKSSAKSNMNIVQRMMANIAEIFSPLIPAIIVGGLILGFRNIIGDIKMFENGTKTLIEISQFWAGTHSFL
WLIGEAIFHFLPVGITWTVTKKMGTTQILGIVLGITLVSPQLLNAYSVATAESIPFWDFGFTKINMIGYQSQVIPAILAG
FVLVYLEKGVRKIVPSSISMIFVPFFALVPTVLIAHTVLGPIGWVIGSWVSAVVYGGLTSAFGSIFAAIFGFLYAPLVIT
GLHHMTNAIDLQLMAEFNGTALWPMIALSNIAQGSAVLAIIYLQRKNEEEKQIAIPACISAYLGVTEPALFGINIKYRFP
FVCGMVGSAIAAIISVSTGVMANSVGIGGLPGILSIKPQHMLMFAIAMVAAIVVPFMLTLIIGKKKLV

Sequences:

>Translated_468_residues
MSKYSKEVKELLEYIGGEENVNAVSHCATRMRFVLNDTSIADEEKIKKIKFVKGTFTQAGQFQVIIGNDVAEFYNEFTAL
AGIDGVSKDNLKSSAKSNMNIVQRMMANIAEIFSPLIPAIIVGGLILGFRNIIGDIKMFENGTKTLIEISQFWAGTHSFL
WLIGEAIFHFLPVGITWTVTKKMGTTQILGIVLGITLVSPQLLNAYSVATAESIPFWDFGFTKINMIGYQSQVIPAILAG
FVLVYLEKGVRKIVPSSISMIFVPFFALVPTVLIAHTVLGPIGWVIGSWVSAVVYGGLTSAFGSIFAAIFGFLYAPLVIT
GLHHMTNAIDLQLMAEFNGTALWPMIALSNIAQGSAVLAIIYLQRKNEEEKQIAIPACISAYLGVTEPALFGINIKYRFP
FVCGMVGSAIAAIISVSTGVMANSVGIGGLPGILSIKPQHMLMFAIAMVAAIVVPFMLTLIIGKKKLV
>Mature_467_residues
SKYSKEVKELLEYIGGEENVNAVSHCATRMRFVLNDTSIADEEKIKKIKFVKGTFTQAGQFQVIIGNDVAEFYNEFTALA
GIDGVSKDNLKSSAKSNMNIVQRMMANIAEIFSPLIPAIIVGGLILGFRNIIGDIKMFENGTKTLIEISQFWAGTHSFLW
LIGEAIFHFLPVGITWTVTKKMGTTQILGIVLGITLVSPQLLNAYSVATAESIPFWDFGFTKINMIGYQSQVIPAILAGF
VLVYLEKGVRKIVPSSISMIFVPFFALVPTVLIAHTVLGPIGWVIGSWVSAVVYGGLTSAFGSIFAAIFGFLYAPLVITG
LHHMTNAIDLQLMAEFNGTALWPMIALSNIAQGSAVLAIIYLQRKNEEEKQIAIPACISAYLGVTEPALFGINIKYRFPF
VCGMVGSAIAAIISVSTGVMANSVGIGGLPGILSIKPQHMLMFAIAMVAAIVVPFMLTLIIGKKKLV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=468, Percent_Identity=51.2820512820513, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1790159, Length=430, Percent_Identity=26.9767441860465, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI48994906, Length=468, Percent_Identity=27.5641025641026, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1788769, Length=419, Percent_Identity=24.1050119331742, Blast_Score=109, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50619; Mature: 50488

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYSKEVKELLEYIGGEENVNAVSHCATRMRFVLNDTSIADEEKIKKIKFVKGTFTQAG
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
QFQVIIGNDVAEFYNEFTALAGIDGVSKDNLKSSAKSNMNIVQRMMANIAEIFSPLIPAI
CEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGGLILGFRNIIGDIKMFENGTKTLIEISQFWAGTHSFLWLIGEAIFHFLPVGITWTVT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEE
KKMGTTQILGIVLGITLVSPQLLNAYSVATAESIPFWDFGFTKINMIGYQSQVIPAILAG
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
FVLVYLEKGVRKIVPSSISMIFVPFFALVPTVLIAHTVLGPIGWVIGSWVSAVVYGGLTS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGSIFAAIFGFLYAPLVITGLHHMTNAIDLQLMAEFNGTALWPMIALSNIAQGSAVLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCEEEE
IYLQRKNEEEKQIAIPACISAYLGVTEPALFGINIKYRFPFVCGMVGSAIAAIISVSTGV
EEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCH
MANSVGIGGLPGILSIKPQHMLMFAIAMVAAIVVPFMLTLIIGKKKLV
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKYSKEVKELLEYIGGEENVNAVSHCATRMRFVLNDTSIADEEKIKKIKFVKGTFTQAG
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
QFQVIIGNDVAEFYNEFTALAGIDGVSKDNLKSSAKSNMNIVQRMMANIAEIFSPLIPAI
CEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGGLILGFRNIIGDIKMFENGTKTLIEISQFWAGTHSFLWLIGEAIFHFLPVGITWTVT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEE
KKMGTTQILGIVLGITLVSPQLLNAYSVATAESIPFWDFGFTKINMIGYQSQVIPAILAG
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
FVLVYLEKGVRKIVPSSISMIFVPFFALVPTVLIAHTVLGPIGWVIGSWVSAVVYGGLTS
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGSIFAAIFGFLYAPLVITGLHHMTNAIDLQLMAEFNGTALWPMIALSNIAQGSAVLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCCCCCEEEE
IYLQRKNEEEKQIAIPACISAYLGVTEPALFGINIKYRFPFVCGMVGSAIAAIISVSTGV
EEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHCH
MANSVGIGGLPGILSIKPQHMLMFAIAMVAAIVVPFMLTLIIGKKKLV
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]