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The map label for this gene is aroD

Identifier: 187935340

GI number: 187935340

Start: 2311121

End: 2311885

Strand: Reverse

Name: aroD

Synonym: CLL_A2227

Alternate gene names: 187935340

Gene position: 2311885-2311121 (Counterclockwise)

Preceding gene: 187934428

Following gene: 187933176

Centisome position: 60.83

GC content: 28.1

Gene sequence:

>765_bases
ATGAAAAGGATAGTACAAGTAAAGAATGTTAAAATAGGTGAAGGCATACCTAAAATATGCGTACCTATTGTTGGGGCAAC
AAGTAAAGAAATATTAGATGAAGCAGAAAAGTTAAAAGAGTTAACTTTAGATATAGTTGAATGGCGAGTTGATTTTTACG
AAGAAGTTTTTGACATAGAAAAGGTAAAGGACACTCTTTCAAAATTAACAACCACTTTAAATGAAGTTCCACTTATTTTT
ACATTTAGAAATAAAATAGAAGGTGGAGAAAGAGAAATTCCAATTGAATATTATTTGAAATTAAATTTAGAAGTAGCAAA
GACTAAATTAGTAGATTTAATTGATGTTGAGCTGTTTATAGGTGATGATTTAGTAAAAGAGATAGTAGAAGTTGCACATG
ATAATGACGTTAAAGTTATTATTTCAAATCATGATTTTTTTAAAACTCCATGTAAAGAAGAAATTATATCTAGACTAATT
AAAATGATACAATTGAATGGTGATTTACCTAAAATAGCTGTTATGCCACAATGTGAAATAGATGTTTTAACTTTACTTTA
TGCTACAAATGAAGTGAAGCATAAATATCCTAATAATTCAATAATAACCATGTCTATGAGTGGAAGAGGTATTATAAGTA
GAATTGCAGGAGAAATTTTTGGATCTTGTTTAACTTTTGGTGCTGCAAAAAAAGCATCAGCACCTGGGCAAATAGGGGTT
GAAGAATTAAATTCTGTACTTAAAGTATTGCATGAAAATATATAA

Upstream 100 bases:

>100_bases
AGAAGTAGCAACGATACTAAATAAATATTAGTGAAATATTAGGTTATTATAAAAAATTATATTATTTAACAAAAGGAAAG
ATATATTGGGGGCAATAAAT

Downstream 100 bases:

>100_bases
TTTAAAGGGAGCTACTAATAGAGTGGCTCCCTTTTCATATATAGAAAGTTGTAGAATTCTAATATATAATTTTTTATAAA
GTATATAGATCTCCAGAGGC

Product: 3-dehydroquinate dehydratase, type I

Products: NA

Alternate protein names: 3-dehydroquinase; Type I DHQase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKRIVQVKNVKIGEGIPKICVPIVGATSKEILDEAEKLKELTLDIVEWRVDFYEEVFDIEKVKDTLSKLTTTLNEVPLIF
TFRNKIEGGEREIPIEYYLKLNLEVAKTKLVDLIDVELFIGDDLVKEIVEVAHDNDVKVIISNHDFFKTPCKEEIISRLI
KMIQLNGDLPKIAVMPQCEIDVLTLLYATNEVKHKYPNNSIITMSMSGRGIISRIAGEIFGSCLTFGAAKKASAPGQIGV
EELNSVLKVLHENI

Sequences:

>Translated_254_residues
MKRIVQVKNVKIGEGIPKICVPIVGATSKEILDEAEKLKELTLDIVEWRVDFYEEVFDIEKVKDTLSKLTTTLNEVPLIF
TFRNKIEGGEREIPIEYYLKLNLEVAKTKLVDLIDVELFIGDDLVKEIVEVAHDNDVKVIISNHDFFKTPCKEEIISRLI
KMIQLNGDLPKIAVMPQCEIDVLTLLYATNEVKHKYPNNSIITMSMSGRGIISRIAGEIFGSCLTFGAAKKASAPGQIGV
EELNSVLKVLHENI
>Mature_254_residues
MKRIVQVKNVKIGEGIPKICVPIVGATSKEILDEAEKLKELTLDIVEWRVDFYEEVFDIEKVKDTLSKLTTTLNEVPLIF
TFRNKIEGGEREIPIEYYLKLNLEVAKTKLVDLIDVELFIGDDLVKEIVEVAHDNDVKVIISNHDFFKTPCKEEIISRLI
KMIQLNGDLPKIAVMPQCEIDVLTLLYATNEVKHKYPNNSIITMSMSGRGIISRIAGEIFGSCLTFGAAKKASAPGQIGV
EELNSVLKVLHENI

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; third step. [C]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family

Homologues:

Organism=Escherichia coli, GI1787984, Length=250, Percent_Identity=52.4, Blast_Score=266, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROD_CLOBB (B2TQ57)

Other databases:

- EMBL:   CP001056
- RefSeq:   YP_001886416.1
- GeneID:   6293885
- GenomeReviews:   CP001056_GR
- KEGG:   cbk:CLL_A2227
- HOGENOM:   HBG732926
- OMA:   IEGGERE
- ProtClustDB:   CLSK2322871
- HAMAP:   MF_00214
- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR01093

Pfam domain/function: PF01487 DHquinase_I

EC number: =4.2.1.10

Molecular weight: Translated: 28553; Mature: 28553

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: ACT_SITE 144-144 ACT_SITE 171-171

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVQVKNVKIGEGIPKICVPIVGATSKEILDEAEKLKELTLDIVEWRVDFYEEVFDIE
CCCCEEECCEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVKDTLSKLTTTLNEVPLIFTFRNKIEGGEREIPIEYYLKLNLEVAKTKLVDLIDVELFI
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHEEE
GDDLVKEIVEVAHDNDVKVIISNHDFFKTPCKEEIISRLIKMIQLNGDLPKIAVMPQCEI
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCH
DVLTLLYATNEVKHKYPNNSIITMSMSGRGIISRIAGEIFGSCLTFGAAKKASAPGQIGV
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
EELNSVLKVLHENI
HHHHHHHHHHHHCC
>Mature Secondary Structure
MKRIVQVKNVKIGEGIPKICVPIVGATSKEILDEAEKLKELTLDIVEWRVDFYEEVFDIE
CCCCEEECCEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KVKDTLSKLTTTLNEVPLIFTFRNKIEGGEREIPIEYYLKLNLEVAKTKLVDLIDVELFI
HHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHEEE
GDDLVKEIVEVAHDNDVKVIISNHDFFKTPCKEEIISRLIKMIQLNGDLPKIAVMPQCEI
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCH
DVLTLLYATNEVKHKYPNNSIITMSMSGRGIISRIAGEIFGSCLTFGAAKKASAPGQIGV
HHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
EELNSVLKVLHENI
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA