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The map label for this gene is blaR1 [H]

Identifier: 187934087

GI number: 187934087

Start: 2244196

End: 2245923

Strand: Reverse

Name: blaR1 [H]

Synonym: CLL_A2154

Alternate gene names: 187934087

Gene position: 2245923-2244196 (Counterclockwise)

Preceding gene: 187935527

Following gene: 187933317

Centisome position: 59.1

GC content: 24.25

Gene sequence:

>1728_bases
ATGAATTTTTTCGAGACTACTATAGTTTCTTCTTTCATTGGAAGCATAATAGTATTAATTATATTAAGCATAAATAGCAT
ATTTAGATATAAGTTAAATCCTACATTTCATTATTATATATGGATAATATTGATTGTAAAATTAATATTTCCTTTTGGGC
CAGAAAACTCTCTGAATTTTTCTCATATATACCAAAGAGTATATATAGAGAATAATGCAAATGAAAACTCACTAAAAGTA
CAAGAAAATTCTATAAAACAATCTCAAAATTCAGATTTAGAAGATTTAAAATCAAAAAATTCTTTTCAAAATTCAAATAA
TAATAAACTCACCTTAAAAACCAATATACCGTTGAAAAATCAACTTCACATTAAGAAAATATTCGTTTCCTTATGGATAT
TAGGTGTAATAGTGCTAATATGCATATTTATTTTAGCACATAAAAAACTTAAACAAATAGTTGAAACTTCTATTAAAAAA
GTAACTAATGAGCATAAAGAAATTTTAAATAATTGTATAAACATTATTCATATAAAAACTAAAGTAAAATTATTATATTC
TTCAAAAATAAGCAGTCCCTGTTTATGTGGATTAGTTAAACCAAAGATATTAATTCCAATAAGCTTAGTAGAGAACATTA
GCGCATCTGACTTTAAATACATTTTAATGCATGAATTAATTCATTTAAAAAGGAGAGATATACTAATAAACTGGATCATA
ATTTTATTGTCCATTATTTACTGGTTTAATCCAATAGTTATTTATGGTCTTAGTAGAATTAAAAAAGACTGTGAATTTTC
ATGTGATAATAATGCAATTTCTTATTTGAATGAAAATGAAAATATACAATATGGTAATGTGTTAATAAAAGTAGTGGCTT
TATGTAGAAGCAATAATAGACTTATAGGAACTACTTCAATGGTTAGAGATAATTTAGAGATTAAAAGGAGGATTATCATG
ATTTCAAAATATAAGAAAATAAATTTTAAAGGAGTATTACTTAGTAGTATTATTGTCGTTATTATAGGGGGAGTAGCAGT
TGGGGTAAATGCTTCAAAATTAAATATTGATAATACAGTAAAAGCACAAGTTTCAACTTTTGATAATATAGCTAGTAATA
ATACAGAAGATCAAACATTATCAACCAATGAAAATAATATATCAAATGATAACTCAAATTCTGTAGTTTCATTTTCATCT
GATATTATAATTTATAATAGTCATGTTGATGAAGATTATCGATCTGGGATAAATGTAACTGATATAGGTGCTTTAATTAA
TGATAAACTTATAAAAGAAGGTTTAAGTAGTAATTTTATTGAGTGCAAGGCTCCTAAAGAATATACTGAATCATATCAAA
ATTCACGTGATTTAATAAAAGCAGATGTTAAAGATTATTCAAATAATATTTTATTGGATATACATCGAGATGCAGTAAAT
AGTACTAAATGTGATACAAAAAATATAACATTAGTTCTTGCTAAAAATAGTCCTTATTATGAGAACAATAAGGTATTTGC
TGAAAGTTTATTACAAAATATAAATAGTTCAAATGAAATTAAAGCAAAAATAATTTCGTATAATCGTGGTAAGTTATGCT
TTAATCAGGATTTATCTAAAAATGCGTTGCTTATTAACTTGGGAAATAACATGTCTAGTGATAGTGATATAGAAAAGTGC
GTAAATGCACTTGTTTCATCTTTAAAGGAAACCAAAAAGGATAGTTAG

Upstream 100 bases:

>100_bases
TGCTTTTAAACTTTGTTGAATCAAAAGAAATATCTGAAACAGACATAGAAGAATTAAAGAACATACTCAAACAATCAAAT
AAAAAGAAAGGTTGAAGTGT

Downstream 100 bases:

>100_bases
GAATATTAGTTAAATGTTTTTAAATTAGGCTGTGTTTTAAATAAATGTTGATAAATGAATTATAATTATATTTTTCTTTT
CTATGTAAATACCCCTTTTT

Product: peptidase, M56 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MNFFETTIVSSFIGSIIVLIILSINSIFRYKLNPTFHYYIWIILIVKLIFPFGPENSLNFSHIYQRVYIENNANENSLKV
QENSIKQSQNSDLEDLKSKNSFQNSNNNKLTLKTNIPLKNQLHIKKIFVSLWILGVIVLICIFILAHKKLKQIVETSIKK
VTNEHKEILNNCINIIHIKTKVKLLYSSKISSPCLCGLVKPKILIPISLVENISASDFKYILMHELIHLKRRDILINWII
ILLSIIYWFNPIVIYGLSRIKKDCEFSCDNNAISYLNENENIQYGNVLIKVVALCRSNNRLIGTTSMVRDNLEIKRRIIM
ISKYKKINFKGVLLSSIIVVIIGGVAVGVNASKLNIDNTVKAQVSTFDNIASNNTEDQTLSTNENNISNDNSNSVVSFSS
DIIIYNSHVDEDYRSGINVTDIGALINDKLIKEGLSSNFIECKAPKEYTESYQNSRDLIKADVKDYSNNILLDIHRDAVN
STKCDTKNITLVLAKNSPYYENNKVFAESLLQNINSSNEIKAKIISYNRGKLCFNQDLSKNALLINLGNNMSSDSDIEKC
VNALVSSLKETKKDS

Sequences:

>Translated_575_residues
MNFFETTIVSSFIGSIIVLIILSINSIFRYKLNPTFHYYIWIILIVKLIFPFGPENSLNFSHIYQRVYIENNANENSLKV
QENSIKQSQNSDLEDLKSKNSFQNSNNNKLTLKTNIPLKNQLHIKKIFVSLWILGVIVLICIFILAHKKLKQIVETSIKK
VTNEHKEILNNCINIIHIKTKVKLLYSSKISSPCLCGLVKPKILIPISLVENISASDFKYILMHELIHLKRRDILINWII
ILLSIIYWFNPIVIYGLSRIKKDCEFSCDNNAISYLNENENIQYGNVLIKVVALCRSNNRLIGTTSMVRDNLEIKRRIIM
ISKYKKINFKGVLLSSIIVVIIGGVAVGVNASKLNIDNTVKAQVSTFDNIASNNTEDQTLSTNENNISNDNSNSVVSFSS
DIIIYNSHVDEDYRSGINVTDIGALINDKLIKEGLSSNFIECKAPKEYTESYQNSRDLIKADVKDYSNNILLDIHRDAVN
STKCDTKNITLVLAKNSPYYENNKVFAESLLQNINSSNEIKAKIISYNRGKLCFNQDLSKNALLINLGNNMSSDSDIEKC
VNALVSSLKETKKDS
>Mature_575_residues
MNFFETTIVSSFIGSIIVLIILSINSIFRYKLNPTFHYYIWIILIVKLIFPFGPENSLNFSHIYQRVYIENNANENSLKV
QENSIKQSQNSDLEDLKSKNSFQNSNNNKLTLKTNIPLKNQLHIKKIFVSLWILGVIVLICIFILAHKKLKQIVETSIKK
VTNEHKEILNNCINIIHIKTKVKLLYSSKISSPCLCGLVKPKILIPISLVENISASDFKYILMHELIHLKRRDILINWII
ILLSIIYWFNPIVIYGLSRIKKDCEFSCDNNAISYLNENENIQYGNVLIKVVALCRSNNRLIGTTSMVRDNLEIKRRIIM
ISKYKKINFKGVLLSSIIVVIIGGVAVGVNASKLNIDNTVKAQVSTFDNIASNNTEDQTLSTNENNISNDNSNSVVSFSS
DIIIYNSHVDEDYRSGINVTDIGALINDKLIKEGLSSNFIECKAPKEYTESYQNSRDLIKADVKDYSNNILLDIHRDAVN
STKCDTKNITLVLAKNSPYYENNKVFAESLLQNINSSNEIKAKIISYNRGKLCFNQDLSKNALLINLGNNMSSDSDIEKC
VNALVSSLKETKKDS

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65226; Mature: 65226

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFFETTIVSSFIGSIIVLIILSINSIFRYKLNPTFHYYIWIILIVKLIFPFGPENSLNF
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCH
SHIYQRVYIENNANENSLKVQENSIKQSQNSDLEDLKSKNSFQNSNNNKLTLKTNIPLKN
HHHHHEEEEECCCCCCCEEEEHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCC
QLHIKKIFVSLWILGVIVLICIFILAHKKLKQIVETSIKKVTNEHKEILNNCINIIHIKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEH
KVKLLYSSKISSPCLCGLVKPKILIPISLVENISASDFKYILMHELIHLKRRDILINWII
HEEEEECCCCCCCCCHHCCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ILLSIIYWFNPIVIYGLSRIKKDCEFSCDNNAISYLNENENIQYGNVLIKVVALCRSNNR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHCCCCE
LIGTTSMVRDNLEIKRRIIMISKYKKINFKGVLLSSIIVVIIGGVAVGVNASKLNIDNTV
EEEEHHHHHCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCHHCCCCCCEECCCCCH
KAQVSTFDNIASNNTEDQTLSTNENNISNDNSNSVVSFSSDIIIYNSHVDEDYRSGINVT
HHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCEEEECCCEEEEECCCCHHHHCCCCHH
DIGALINDKLIKEGLSSNFIECKAPKEYTESYQNSRDLIKADVKDYSNNILLDIHRDAVN
HHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCC
STKCDTKNITLVLAKNSPYYENNKVFAESLLQNINSSNEIKAKIISYNRGKLCFNQDLSK
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCC
NALLINLGNNMSSDSDIEKCVNALVSSLKETKKDS
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNFFETTIVSSFIGSIIVLIILSINSIFRYKLNPTFHYYIWIILIVKLIFPFGPENSLNF
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCH
SHIYQRVYIENNANENSLKVQENSIKQSQNSDLEDLKSKNSFQNSNNNKLTLKTNIPLKN
HHHHHEEEEECCCCCCCEEEEHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEECCCCCC
QLHIKKIFVSLWILGVIVLICIFILAHKKLKQIVETSIKKVTNEHKEILNNCINIIHIKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEH
KVKLLYSSKISSPCLCGLVKPKILIPISLVENISASDFKYILMHELIHLKRRDILINWII
HEEEEECCCCCCCCCHHCCCCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ILLSIIYWFNPIVIYGLSRIKKDCEFSCDNNAISYLNENENIQYGNVLIKVVALCRSNNR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEHHHHHHHHHHHHCCCCE
LIGTTSMVRDNLEIKRRIIMISKYKKINFKGVLLSSIIVVIIGGVAVGVNASKLNIDNTV
EEEEHHHHHCCHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHCCHHCCCCCCEECCCCCH
KAQVSTFDNIASNNTEDQTLSTNENNISNDNSNSVVSFSSDIIIYNSHVDEDYRSGINVT
HHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCEEEECCCEEEEECCCCHHHHCCCCHH
DIGALINDKLIKEGLSSNFIECKAPKEYTESYQNSRDLIKADVKDYSNNILLDIHRDAVN
HHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCC
STKCDTKNITLVLAKNSPYYENNKVFAESLLQNINSSNEIKAKIISYNRGKLCFNQDLSK
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCEEECCCCCC
NALLINLGNNMSSDSDIEKCVNALVSSLKETKKDS
CEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]