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The map label for this gene is bdhA [H]

Identifier: 187934085

GI number: 187934085

Start: 2606227

End: 2607390

Strand: Reverse

Name: bdhA [H]

Synonym: CLL_A2510

Alternate gene names: 187934085

Gene position: 2607390-2606227 (Counterclockwise)

Preceding gene: 187935235

Following gene: 187935153

Centisome position: 68.61

GC content: 30.5

Gene sequence:

>1164_bases
ATGGAAAATTTTAATTATTCAATACCAACTGAAATTTATTTTGGAAAAGGACAAATAAAACATTTAGGCAATGCTATAAA
AAAATATGGAAGTAAAGTTCTTGTTGTATATGGTGGGGGAAGTATTAAAAGAATAGGTTTATATGATGAGATGATAAAAA
TATTAAAAGATAATAATATATCACATGTAGAACTTTCTAATATAGCACCAAATCCTAGAATAGAGTCTGTTAGAGATGGG
GTAAAACTTTGTAGAGACAATGATGTAGAGGTTGTTTTAGCTGTTGGAGGAGGAAGTACAATAGACTGTGCTAAAGTTAT
TGCAGCAGGAGTAAACTATGATAAAGATCCATGGGATATTGTATTAGATTCAAGCAAAATGACAAAAGTATTACCTATAA
TAACTATTTTAACTTTATCAGCAACAGGCTCAGAAATGGATCCATTTGCAGTAATATCGGATATGAGCAAAAATGAAAAA
ATAGGTGTTGGCAATGATAAAATGAAACCTAAAGTTTCAATATTAGATCCAGAATATACTTACTCTGTTCCTAAAAATCA
AACAGCGGCAGGAACAGCAGATATTATGAGTCATATATTTGAAAATTATTTTAATAACACTAAAGGTGCATTTATTCAAG
CAAGAACTGCTGAAGGGTTACTTAAAGCATGTATGAAGTATGGAAAAATAGTGATAGAAGAGCCTAATAATTATGAAGCA
AGAGCAAATTTAATGTGGGCTTCTAGTTTAGCTATTAATGGCTTAATATCATATGGGACAGCTGGAGCATGGTCAGTGCA
TCCAATGGAGCATGAATTAAGTGCATTCTATGATATAACACATGGAGTTGGATTAGCGATTTTAACACCTCATTGGATGA
GATATGTGTTAAATGATGATACTTTATATAAATTCGTTGAGTATGGAGTAAATGTATGGAATATAGATAAGAATTTAGAT
GAATATACTATAGCTAATACTGCAATAGATAAAACAGCAGAATTCTTTAAAGAGTTGGGAATTCCATCAACGTTAAGAGA
AGTTGGAATTGGAAAAGAAAACTTTGAAATTATGGCACAAAAAGCAGTTAAATCAGGATTAGAATATGGATTTAAATCAC
TTACACCAGAAGATGTAGTAAAAATATATAAAGCTGCATTATAA

Upstream 100 bases:

>100_bases
TCTAAAATACAATTAGAATATCACTTTAAATATTGAATATATAAGTATATATTTAAAATATAACCTAATATAATTAAATG
TATCATAAGGAGAGGTTAAT

Downstream 100 bases:

>100_bases
ATGCTATGTTTCATAAAAATGTTTATATATAATTAATATAAAAATAAAAGTTACTACATGTAAAGTATATTTATCATGTA
GTAACTTTTTTATTTATATC

Product: NADH-dependent butanol dehydrogenase a

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MENFNYSIPTEIYFGKGQIKHLGNAIKKYGSKVLVVYGGGSIKRIGLYDEMIKILKDNNISHVELSNIAPNPRIESVRDG
VKLCRDNDVEVVLAVGGGSTIDCAKVIAAGVNYDKDPWDIVLDSSKMTKVLPIITILTLSATGSEMDPFAVISDMSKNEK
IGVGNDKMKPKVSILDPEYTYSVPKNQTAAGTADIMSHIFENYFNNTKGAFIQARTAEGLLKACMKYGKIVIEEPNNYEA
RANLMWASSLAINGLISYGTAGAWSVHPMEHELSAFYDITHGVGLAILTPHWMRYVLNDDTLYKFVEYGVNVWNIDKNLD
EYTIANTAIDKTAEFFKELGIPSTLREVGIGKENFEIMAQKAVKSGLEYGFKSLTPEDVVKIYKAAL

Sequences:

>Translated_387_residues
MENFNYSIPTEIYFGKGQIKHLGNAIKKYGSKVLVVYGGGSIKRIGLYDEMIKILKDNNISHVELSNIAPNPRIESVRDG
VKLCRDNDVEVVLAVGGGSTIDCAKVIAAGVNYDKDPWDIVLDSSKMTKVLPIITILTLSATGSEMDPFAVISDMSKNEK
IGVGNDKMKPKVSILDPEYTYSVPKNQTAAGTADIMSHIFENYFNNTKGAFIQARTAEGLLKACMKYGKIVIEEPNNYEA
RANLMWASSLAINGLISYGTAGAWSVHPMEHELSAFYDITHGVGLAILTPHWMRYVLNDDTLYKFVEYGVNVWNIDKNLD
EYTIANTAIDKTAEFFKELGIPSTLREVGIGKENFEIMAQKAVKSGLEYGFKSLTPEDVVKIYKAAL
>Mature_387_residues
MENFNYSIPTEIYFGKGQIKHLGNAIKKYGSKVLVVYGGGSIKRIGLYDEMIKILKDNNISHVELSNIAPNPRIESVRDG
VKLCRDNDVEVVLAVGGGSTIDCAKVIAAGVNYDKDPWDIVLDSSKMTKVLPIITILTLSATGSEMDPFAVISDMSKNEK
IGVGNDKMKPKVSILDPEYTYSVPKNQTAAGTADIMSHIFENYFNNTKGAFIQARTAEGLLKACMKYGKIVIEEPNNYEA
RANLMWASSLAINGLISYGTAGAWSVHPMEHELSAFYDITHGVGLAILTPHWMRYVLNDDTLYKFVEYGVNVWNIDKNLD
EYTIANTAIDKTAEFFKELGIPSTLREVGIGKENFEIMAQKAVKSGLEYGFKSLTPEDVVKIYKAAL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=331, Percent_Identity=24.1691842900302, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1789386, Length=392, Percent_Identity=38.5204081632653, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI48994951, Length=400, Percent_Identity=30.25, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789163, Length=381, Percent_Identity=27.0341207349081, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87082107, Length=393, Percent_Identity=26.4631043256997, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1787493, Length=377, Percent_Identity=25.4641909814324, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17537053, Length=423, Percent_Identity=22.9314420803783, Blast_Score=92, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321181, Length=389, Percent_Identity=27.7634961439589, Blast_Score=141, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24657991, Length=394, Percent_Identity=21.0659898477157, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42754; Mature: 42754

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENFNYSIPTEIYFGKGQIKHLGNAIKKYGSKVLVVYGGGSIKRIGLYDEMIKILKDNNI
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCEEEECHHHHHHHHHHCCCC
SHVELSNIAPNPRIESVRDGVKLCRDNDVEVVLAVGGGSTIDCAKVIAAGVNYDKDPWDI
CEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEE
VLDSSKMTKVLPIITILTLSATGSEMDPFAVISDMSKNEKIGVGNDKMKPKVSILDPEYT
EECCCHHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEE
YSVPKNQTAAGTADIMSHIFENYFNNTKGAFIQARTAEGLLKACMKYGKIVIEEPNNYEA
ECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCEEEEECCCCCCC
RANLMWASSLAINGLISYGTAGAWSVHPMEHELSAFYDITHGVGLAILTPHWMRYVLNDD
CEEEEEEHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCH
TLYKFVEYGVNVWNIDKNLDEYTIANTAIDKTAEFFKELGIPSTLREVGIGKENFEIMAQ
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHH
KAVKSGLEYGFKSLTPEDVVKIYKAAL
HHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MENFNYSIPTEIYFGKGQIKHLGNAIKKYGSKVLVVYGGGSIKRIGLYDEMIKILKDNNI
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCEEEECHHHHHHHHHHCCCC
SHVELSNIAPNPRIESVRDGVKLCRDNDVEVVLAVGGGSTIDCAKVIAAGVNYDKDPWDI
CEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEE
VLDSSKMTKVLPIITILTLSATGSEMDPFAVISDMSKNEKIGVGNDKMKPKVSILDPEYT
EECCCHHHHHHHHHHHEEEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEE
YSVPKNQTAAGTADIMSHIFENYFNNTKGAFIQARTAEGLLKACMKYGKIVIEEPNNYEA
ECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCEEEEECCCCCCC
RANLMWASSLAINGLISYGTAGAWSVHPMEHELSAFYDITHGVGLAILTPHWMRYVLNDD
CEEEEEEHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCH
TLYKFVEYGVNVWNIDKNLDEYTIANTAIDKTAEFFKELGIPSTLREVGIGKENFEIMAQ
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHH
KAVKSGLEYGFKSLTPEDVVKIYKAAL
HHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]