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The map label for this gene is mta [H]

Identifier: 187933153

GI number: 187933153

Start: 1953493

End: 1954248

Strand: Reverse

Name: mta [H]

Synonym: CLL_A1857

Alternate gene names: 187933153

Gene position: 1954248-1953493 (Counterclockwise)

Preceding gene: 187932636

Following gene: 187933924

Centisome position: 51.42

GC content: 25.0

Gene sequence:

>756_bases
ATGGATTATACAATAAAGGAATTAAGCAAAATTGCTGGTGTAAGCAGTAGAACATTGAGATACTATGATGAGATTGATTT
ATTAAAACCTTGTAGAGTGAATTCATCTGGATATAGAATATACAGTGGAAATGAGGTTGACTTACTTCAGCAAATATTAT
TTTATAGAGAATTGGATTTGCCTTTAAATAAAATTAAAGAAATTATTTCAAAGGATAATTTTGACTACAAAAAAGCTTTA
TACGAGCATAAAGAAAATATTATAAGAAAACAACAAAGGTTTAAAATAATATTAGAAAATATTGAAAAGACTATAGAAAC
AATAGAGGGAGAACAAATTATGAAAGATGAAGAAAAATTTATTGGATTTAAAGAAGAGCTAGTAAAAGAAAATGATAAAA
AATATGGTAAGGAATTGAGAAAAAAATATGGGGAAGAAGTAATAGAAAAAAGTAATGAAAATTTATTAAAATTATCAAAA
GAAGAGTTTTATGAAGTTGAAAAAATAGGAAAAGAAATAAATGAAAAATTAAATGAAGCTTTAAAAATTGGGGATTCAAC
TTCTGAAATTGCTATGGAAGTAGTTAGACTTCATAAAAAATGGCTAAGTTATTATGGAAATTATTCGAAAGAAGCACATA
TAGAATTAGGAGAAATGTATGTGTATGATGAACGATTTAACAAATTTTATACTGAAAATGTTGGGTGTGGTGCAGCTGAA
TTTTTAAAAGATGCAATTATTGAGTTTTATAAGTAA

Upstream 100 bases:

>100_bases
TTAATGGGAAGGAGAAGTATTAATAGTGTTTTTATTATAATATCTATATTGACATTAACGCCACGTAAACATATATACTT
GAGATAAAGGGGTGATAAAA

Downstream 100 bases:

>100_bases
TGCACATTGTTTAACAGTGAAACATCATCCTTAAAATGAATATTTTATTATGTAATTTAGATTACATTAGTAATTCTATT
GTAAAAACTATAAATAATTT

Product: MerR-family transcriptional regulator

Products: NA

Alternate protein names: Multidrug transporter activation protein [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MDYTIKELSKIAGVSSRTLRYYDEIDLLKPCRVNSSGYRIYSGNEVDLLQQILFYRELDLPLNKIKEIISKDNFDYKKAL
YEHKENIIRKQQRFKIILENIEKTIETIEGEQIMKDEEKFIGFKEELVKENDKKYGKELRKKYGEEVIEKSNENLLKLSK
EEFYEVEKIGKEINEKLNEALKIGDSTSEIAMEVVRLHKKWLSYYGNYSKEAHIELGEMYVYDERFNKFYTENVGCGAAE
FLKDAIIEFYK

Sequences:

>Translated_251_residues
MDYTIKELSKIAGVSSRTLRYYDEIDLLKPCRVNSSGYRIYSGNEVDLLQQILFYRELDLPLNKIKEIISKDNFDYKKAL
YEHKENIIRKQQRFKIILENIEKTIETIEGEQIMKDEEKFIGFKEELVKENDKKYGKELRKKYGEEVIEKSNENLLKLSK
EEFYEVEKIGKEINEKLNEALKIGDSTSEIAMEVVRLHKKWLSYYGNYSKEAHIELGEMYVYDERFNKFYTENVGCGAAE
FLKDAIIEFYK
>Mature_251_residues
MDYTIKELSKIAGVSSRTLRYYDEIDLLKPCRVNSSGYRIYSGNEVDLLQQILFYRELDLPLNKIKEIISKDNFDYKKAL
YEHKENIIRKQQRFKIILENIEKTIETIEGEQIMKDEEKFIGFKEELVKENDKKYGKELRKKYGEEVIEKSNENLLKLSK
EEFYEVEKIGKEINEKLNEALKIGDSTSEIAMEVVRLHKKWLSYYGNYSKEAHIELGEMYVYDERFNKFYTENVGCGAAE
FLKDAIIEFYK

Specific function: Global transcriptional regulator that activates transcription of bmr and blt by binding directly to their promoter. Stimulates also the expression of the mta gene itself, ydfK and ymfE [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 29868; Mature: 29868

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYTIKELSKIAGVSSRTLRYYDEIDLLKPCRVNSSGYRIYSGNEVDLLQQILFYRELDL
CCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCC
PLNKIKEIISKDNFDYKKALYEHKENIIRKQQRFKIILENIEKTIETIEGEQIMKDEEKF
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IGFKEELVKENDKKYGKELRKKYGEEVIEKSNENLLKLSKEEFYEVEKIGKEINEKLNEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKIGDSTSEIAMEVVRLHKKWLSYYGNYSKEAHIELGEMYVYDERFNKFYTENVGCGAAE
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHCCCCCCHHH
FLKDAIIEFYK
HHHHHHHHHCC
>Mature Secondary Structure
MDYTIKELSKIAGVSSRTLRYYDEIDLLKPCRVNSSGYRIYSGNEVDLLQQILFYRELDL
CCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHCCC
PLNKIKEIISKDNFDYKKALYEHKENIIRKQQRFKIILENIEKTIETIEGEQIMKDEEKF
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
IGFKEELVKENDKKYGKELRKKYGEEVIEKSNENLLKLSKEEFYEVEKIGKEINEKLNEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKIGDSTSEIAMEVVRLHKKWLSYYGNYSKEAHIELGEMYVYDERFNKFYTENVGCGAAE
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHHHHHHHHHHHHCCCCCCHHH
FLKDAIIEFYK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9150240; 9384377 [H]