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The map label for this gene is yycG [H]

Identifier: 187933059

GI number: 187933059

Start: 2747535

End: 2748803

Strand: Reverse

Name: yycG [H]

Synonym: CLL_A2638

Alternate gene names: 187933059

Gene position: 2748803-2747535 (Counterclockwise)

Preceding gene: 187933777

Following gene: 187935765

Centisome position: 72.33

GC content: 23.33

Gene sequence:

>1269_bases
ATGATTAATGATCCAATGAAAAATATGAAAGTAAATTTAGAAAGAACTCATAAGGTGAATTTGGAATTACATAGAACATT
AAAGAAGCGTAATCGTATATTAAATGATACTAATATAATGATAGAAAAAAGTGAAAGTAATTATAATAAATTGATAGATT
CTGTATATGATGGTGTACTTTTATTTTCAAAAAATAAATTACAATATATAAATAAAGCAGGATTAAAATTATTAAATGAT
GTAAATAAAGAAAACATTATAGGAATTAGTTTAGAAAAATTTATTTTAGATAATTTCAATTTTACTTTACAGCCTGGCAC
TGAAAAAGAAATGTGCATAAGTGATCTTAAACTAAATAATGCAGATATAATGGTAACTTTATTTATAATAGATATAGATG
AAAATAATAAGTTATTATATGCGCATGATGTAACTGAATTAAATAAAACTAAAGATATGAAAAACAAATTAGAGAAGTAT
TTAAAAGAAGAGGAATTAAAAAATCAATTTTTCTCCAATATTTCTCATGAATTACGTACTCCAATAAATTTAATATATTC
AGCTATACAACTTAATGAAATTTATTTAAAGCAAAAAAAAGTTAATAATATAAGTAAAAATAATGATATAATAAGGCAAA
ATTCTTTAAGACTCATAAGGACTATAAATAATTTTATAGACACAAATAGGGTATCTGAGGGATATCTTAAACCAGATTTC
AAAATTTACAATATTGTTGAAGTGGTTGAAAATATAACTATTGCATGTAATAAATATGTAGATAGAGCTGAAATAGGTTT
AACATTTGATTCAGAAAAAGAAGAATTGTTTGTAAGATGTGATAAAGATATGATTGAAAGAATTATATTAAATATTATGT
CAAACTCTGTTAAATATGGACAAAAAGGTAGCCATATAAATGTGACTATAGGCATAGAAGAAGGCAATTTAGTTACAATA
AAAATTGAGAATAACGGAAATAGAATTGATGAAGACACAATACCTCATATATTTGATAAATTTACAAGAATAAATAAATC
TCTGAATAGACCTAAAGAGGGAAGTGGCTTAGGATTATTCTTAAGTAAATCATTGACAGAATTACAAGGGGGAGAGCTTG
CTTTAGAGTTAGATGAAAAAGAAAACTTATTTGTAATAAACTTTCCTATTGCTTGTGATGTTAATTCTTCAGATGTAAAT
TGTGATTTAGAAATTAATAATATAGAAGAAAAAGTAGATATAGAATTTTCAGATATATATATGGACTAG

Upstream 100 bases:

>100_bases
AGTTAGTACAATCTTAATTAGTAGTAATAAGTTAATTATAATAGCTGGAGCATTGAAATTATTAGCTTTTTATGTATTAT
TTAAAGGGATGGTAAATTAT

Downstream 100 bases:

>100_bases
TGAAGAGTGTTTCTAATTGTGGTTATATTTTAGCAAAGTATTGTGATATCTGTGTAATAAAAGTATGTTTTCCTAGACCC
TACACAATGTGCCAATAAAA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MINDPMKNMKVNLERTHKVNLELHRTLKKRNRILNDTNIMIEKSESNYNKLIDSVYDGVLLFSKNKLQYINKAGLKLLND
VNKENIIGISLEKFILDNFNFTLQPGTEKEMCISDLKLNNADIMVTLFIIDIDENNKLLYAHDVTELNKTKDMKNKLEKY
LKEEELKNQFFSNISHELRTPINLIYSAIQLNEIYLKQKKVNNISKNNDIIRQNSLRLIRTINNFIDTNRVSEGYLKPDF
KIYNIVEVVENITIACNKYVDRAEIGLTFDSEKEELFVRCDKDMIERIILNIMSNSVKYGQKGSHINVTIGIEEGNLVTI
KIENNGNRIDEDTIPHIFDKFTRINKSLNRPKEGSGLGLFLSKSLTELQGGELALELDEKENLFVINFPIACDVNSSDVN
CDLEINNIEEKVDIEFSDIYMD

Sequences:

>Translated_422_residues
MINDPMKNMKVNLERTHKVNLELHRTLKKRNRILNDTNIMIEKSESNYNKLIDSVYDGVLLFSKNKLQYINKAGLKLLND
VNKENIIGISLEKFILDNFNFTLQPGTEKEMCISDLKLNNADIMVTLFIIDIDENNKLLYAHDVTELNKTKDMKNKLEKY
LKEEELKNQFFSNISHELRTPINLIYSAIQLNEIYLKQKKVNNISKNNDIIRQNSLRLIRTINNFIDTNRVSEGYLKPDF
KIYNIVEVVENITIACNKYVDRAEIGLTFDSEKEELFVRCDKDMIERIILNIMSNSVKYGQKGSHINVTIGIEEGNLVTI
KIENNGNRIDEDTIPHIFDKFTRINKSLNRPKEGSGLGLFLSKSLTELQGGELALELDEKENLFVINFPIACDVNSSDVN
CDLEINNIEEKVDIEFSDIYMD
>Mature_422_residues
MINDPMKNMKVNLERTHKVNLELHRTLKKRNRILNDTNIMIEKSESNYNKLIDSVYDGVLLFSKNKLQYINKAGLKLLND
VNKENIIGISLEKFILDNFNFTLQPGTEKEMCISDLKLNNADIMVTLFIIDIDENNKLLYAHDVTELNKTKDMKNKLEKY
LKEEELKNQFFSNISHELRTPINLIYSAIQLNEIYLKQKKVNNISKNNDIIRQNSLRLIRTINNFIDTNRVSEGYLKPDF
KIYNIVEVVENITIACNKYVDRAEIGLTFDSEKEELFVRCDKDMIERIILNIMSNSVKYGQKGSHINVTIGIEEGNLVTI
KIENNGNRIDEDTIPHIFDKFTRINKSLNRPKEGSGLGLFLSKSLTELQGGELALELDEKENLFVINFPIACDVNSSDVN
CDLEINNIEEKVDIEFSDIYMD

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=227, Percent_Identity=28.6343612334802, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=233, Percent_Identity=26.6094420600858, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788713, Length=288, Percent_Identity=26.0416666666667, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=26.3374485596708, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788279, Length=248, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=23.6, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=24.5689655172414, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789149, Length=288, Percent_Identity=22.9166666666667, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786600, Length=357, Percent_Identity=24.6498599439776, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48859; Mature: 48859

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDPMKNMKVNLERTHKVNLELHRTLKKRNRILNDTNIMIEKSESNYNKLIDSVYDGVL
CCCCCCCCCEEEEEEEEEECHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCEE
LFSKNKLQYINKAGLKLLNDVNKENIIGISLEKFILDNFNFTLQPGTEKEMCISDLKLNN
EEECCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCEEECCCCCHHHHHHHCEECC
ADIMVTLFIIDIDENNKLLYAHDVTELNKTKDMKNKLEKYLKEEELKNQFFSNISHELRT
CCEEEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PINLIYSAIQLNEIYLKQKKVNNISKNNDIIRQNSLRLIRTINNFIDTNRVSEGYLKPDF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHCHHHHHHHHHHHHHCCCCCCCCCCCCC
KIYNIVEVVENITIACNKYVDRAEIGLTFDSEKEELFVRCDKDMIERIILNIMSNSVKYG
HHHHHHHHHHCCEEEECCCCCHHHEEEEECCCCCCEEEECCHHHHHHHHHHHHHCCCCCC
QKGSHINVTIGIEEGNLVTIKIENNGNRIDEDTIPHIFDKFTRINKSLNRPKEGSGLGLF
CCCCEEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
LSKSLTELQGGELALELDEKENLFVINFPIACDVNSSDVNCDLEINNIEEKVDIEFSDIY
EHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEEEEEE
MD
CC
>Mature Secondary Structure
MINDPMKNMKVNLERTHKVNLELHRTLKKRNRILNDTNIMIEKSESNYNKLIDSVYDGVL
CCCCCCCCCEEEEEEEEEECHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCEE
LFSKNKLQYINKAGLKLLNDVNKENIIGISLEKFILDNFNFTLQPGTEKEMCISDLKLNN
EEECCHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCEEECCCCCHHHHHHHCEECC
ADIMVTLFIIDIDENNKLLYAHDVTELNKTKDMKNKLEKYLKEEELKNQFFSNISHELRT
CCEEEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PINLIYSAIQLNEIYLKQKKVNNISKNNDIIRQNSLRLIRTINNFIDTNRVSEGYLKPDF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHCHHHHHHHHHHHHHCCCCCCCCCCCCC
KIYNIVEVVENITIACNKYVDRAEIGLTFDSEKEELFVRCDKDMIERIILNIMSNSVKYG
HHHHHHHHHHCCEEEECCCCCHHHEEEEECCCCCCEEEECCHHHHHHHHHHHHHCCCCCC
QKGSHINVTIGIEEGNLVTIKIENNGNRIDEDTIPHIFDKFTRINKSLNRPKEGSGLGLF
CCCCEEEEEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEE
LSKSLTELQGGELALELDEKENLFVINFPIACDVNSSDVNCDLEINNIEEKVDIEFSDIY
EHHHHHHCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCEEEEEECCCCCEEEEEEEEEE
MD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]