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The map label for this gene is pcp [H]

Identifier: 187932854

GI number: 187932854

Start: 1593029

End: 1593670

Strand: Reverse

Name: pcp [H]

Synonym: CLL_A1534

Alternate gene names: 187932854

Gene position: 1593670-1593029 (Counterclockwise)

Preceding gene: 187935211

Following gene: 187935772

Centisome position: 41.94

GC content: 31.0

Gene sequence:

>642_bases
ATGAAAGTTTTAATAACTGGCTTTGATCCATTTGGTGGAGAAAGCATAAACCCAGCATTAGAGGCTGTAAAAAAGCTTCC
AAATACAATAAGTAATGCTGAAATAATAAAATTAGAAATCCCTACTGTTTTTAAAAAATCATTAGACAAAATAGAAGAGA
ATATATTAGCTCATAAACCTGATATATTAATCTCAATAGGTCAAGCTGGTGGTCGTTTCGGAATTACACCTGAAAGAGTT
GCGATAAACATTGATGATGCTAGAATCCAAGATAACGAAAAAAATCAACCAATAGATTTAAAAGTATTTGAAGATGGAGA
AAATGCATATTTTACTACTCTTCCAATAAAAGCTATGGTTAAAGAAATGCAAGAAGCTGGCATTCCTAGTTCAGTTTCAA
ATAGTGCTGGAACTTTTGTATGTAACCACGTTATGTATGGAGTATTATATATGATAAATAAAAAATATCCTAATATAAAA
GGCGGCTTTATACATGTTCCATATATACCATCTCAAGTAGTTAATAAACCAAATATGCCCTCTATGTCAATTGAGGATAT
TTCTAAAGGATTAGAATTAAGCGTTAAGGCCGCAGTTGAAAATAACACAGATATTAAAACTGCTCAAGGAGAAATTTGCT
AA

Upstream 100 bases:

>100_bases
TATGTTAATATATGCGATAGGTAAACATACACCGCCTATATCAACACATTACTAAAACATAGCTATGAATTAACATTATA
TTCGAAGGACGTGAATTTAA

Downstream 100 bases:

>100_bases
TGAGCAATATTAATATCTTCGTTTACGGTAGTTTAAGAGAAGGCTTTTTTAACTACAACAAATATTTAGATGGTAAAGTA
ATTGAAGTTAAACCTGCACG

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKVLITGFDPFGGESINPALEAVKKLPNTISNAEIIKLEIPTVFKKSLDKIEENILAHKPDILISIGQAGGRFGITPERV
AINIDDARIQDNEKNQPIDLKVFEDGENAYFTTLPIKAMVKEMQEAGIPSSVSNSAGTFVCNHVMYGVLYMINKKYPNIK
GGFIHVPYIPSQVVNKPNMPSMSIEDISKGLELSVKAAVENNTDIKTAQGEIC

Sequences:

>Translated_213_residues
MKVLITGFDPFGGESINPALEAVKKLPNTISNAEIIKLEIPTVFKKSLDKIEENILAHKPDILISIGQAGGRFGITPERV
AINIDDARIQDNEKNQPIDLKVFEDGENAYFTTLPIKAMVKEMQEAGIPSSVSNSAGTFVCNHVMYGVLYMINKKYPNIK
GGFIHVPYIPSQVVNKPNMPSMSIEDISKGLELSVKAAVENNTDIKTAQGEIC
>Mature_213_residues
MKVLITGFDPFGGESINPALEAVKKLPNTISNAEIIKLEIPTVFKKSLDKIEENILAHKPDILISIGQAGGRFGITPERV
AINIDDARIQDNEKNQPIDLKVFEDGENAYFTTLPIKAMVKEMQEAGIPSSVSNSAGTFVCNHVMYGVLYMINKKYPNIK
GGFIHVPYIPSQVVNKPNMPSMSIEDISKGLELSVKAAVENNTDIKTAQGEIC

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 23302; Mature: 23302

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLITGFDPFGGESINPALEAVKKLPNTISNAEIIKLEIPTVFKKSLDKIEENILAHKP
CEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCC
DILISIGQAGGRFGITPERVAINIDDARIQDNEKNQPIDLKVFEDGENAYFTTLPIKAMV
CEEEEECCCCCCCCCCCCEEEEEECHHEECCCCCCCCEEEEEEECCCCEEEEECCHHHHH
KEMQEAGIPSSVSNSAGTFVCNHVMYGVLYMINKKYPNIKGGFIHVPYIPSQVVNKPNMP
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHCCCCCCC
SMSIEDISKGLELSVKAAVENNTDIKTAQGEIC
CCCHHHHHCCCEEEEEEEECCCCCEECCCCCCC
>Mature Secondary Structure
MKVLITGFDPFGGESINPALEAVKKLPNTISNAEIIKLEIPTVFKKSLDKIEENILAHKP
CEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCC
DILISIGQAGGRFGITPERVAINIDDARIQDNEKNQPIDLKVFEDGENAYFTTLPIKAMV
CEEEEECCCCCCCCCCCCEEEEEECHHEECCCCCCCCEEEEEEECCCCEEEEECCHHHHH
KEMQEAGIPSSVSNSAGTFVCNHVMYGVLYMINKKYPNIKGGFIHVPYIPSQVVNKPNMP
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHCCCCCCC
SMSIEDISKGLELSVKAAVENNTDIKTAQGEIC
CCCHHHHHCCCEEEEEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA