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The map label for this gene is dsbD [H]

Identifier: 187928874

GI number: 187928874

Start: 1886172

End: 1888109

Strand: Reverse

Name: dsbD [H]

Synonym: Rpic_1792

Alternate gene names: 187928874

Gene position: 1888109-1886172 (Counterclockwise)

Preceding gene: 187928875

Following gene: 187928866

Centisome position: 47.89

GC content: 65.89

Gene sequence:

>1938_bases
ATGGGGTGGAGCGTGGCAGCGACGCGCACTGGAGGTGGCGGGCGAGTACGAGGCGTCGCCCCGGCACAGCTCGTTTTGCT
GCTGCTCGCCGCCCTGTGGTTCTGCGTCACAGGCACCGGTGGTGTTGCCCATGCTGCGGGCGAGCAAGACCTCCTGCCAC
CGGAGCAGGCTTTCCGCTTTGCTGCGCGGCAACTCGAAGACCGCTCCATCGAGGTGCACTTCGACATTGCCGACGGCTAT
CACCTCTACCGTGAGCGATTCGCATTCGCCGCACAGCCGGCAGGGGTCAAGCTCGGTACACCCGAATTTCCGCCAGGGCA
GGTCAACTTTGACGAAGCGCTCGGCAAGCAGATGGAGACCTATCATGGCGGGGTCACCATTCGCGTGCCGGTGGCGGTCG
CGCAGGTCGACGGCAAATGGTTGCTGACGGTGACGTCGCAAGGCTGTGCCGACAAGGGAGTCTGCTATCCGCCGATGCAC
AGTGTGTACAAGGTCGGCGGTGGCTCGCTCGGTGGCCTATTCGACAAGCATCGGAGCAGCACGCCAATGACGTCGCCCGC
GCCGCCGGCGACGCCGACTTTGCCCAGCTTGGGAGGGGGGCAAATTGGGCCTGCTGTTCCATCAGCCGCGCCAAGGAATG
ACGACGGCGACCACATTGCCCGCGTGCTGGCCAGCCGCCAGCTGGGCAAGATTGTCACGGTCTTCCTCGGCTTTGGCCTG
CTGCTGACGCTCACGCCGAGCGCGCTGGCGATGGTACTGATCCTGTCGTCAATCGTCGTCGGCGAGCACGTGACGCGCGT
TCGCGCCTTGCTGGTTTCGTTTGCCTACGTGCTCGGAACGGCAGTGGGTGTCGGCGCGGCAGCGGAATTGCTCGGCGAGA
GACTTTCGGCGAGGCTGCAGGCGCCGTGGGCGCTGGGGGCTTTTGCCGCGCTGGCGGTGGCCCTGGCGCTGTCAATGTTC
GGGCTTTATGAGCTGGGGCGGCAGCTCCCAACGACGGCGCCATCGAACCGGTGGTCGGGTGGACGGATTGCCGTTGCCGC
AGCATCGGGGGTGATTTCGACGTTGGTCGTCGTGCGCAGCGTGCCAGTGCCGCTGTCGAGCACGCTGGCCTATCTCAAGC
AAACCGGTGATGCCATTGGTAGTGGCGGTGCACTATTCGGTCTGGCGATCGGCATGGGAGTGACGCTGGTGCTGGTCGGC
GTCGCTACCGGCTATCTTCTGCCGCGCGCTGGGCACTGGTTGATGGTGACGAAGCGCTTCCTGGGCTTCCTGCTGCTCGG
CGAGGCGCTCTGGGCTGTCAGCCCGCTTTTGCCACCCTGGGCATTGATGGCGGCGTGGGCCATGCTGCTGCTGATTGCCG
CCGCCTTCCTGGGCGCCTTCGATTCGCTTGGTCCAGAGCCGCGCAGCATGGCCCGGTTGGGCAAAGGCATGGGCATGGTG
GCCGCGCTGGCAGGGGCGATCCTGCTGGTCGGTCTGGCGTCCGGCGGACGGGATCTGCTCCAGCCGCTGTCGCATCTGCG
TGCTGGCCCGATGGCACCCGCCTCCACTGCTGGCCCGGCGCTGGTGCGCTTCGAGCGCATCCGCTCCGTGGCCGAACTCG
ACGCGCGCCTGGTGCAGGCCGCCGCGGCCGGCAAGCCGGTGCTACTGGATTTCTATGCCGACTGGTGTGTCAGCTGCAAG
GAGATGGAACGCTTGACCTTCAGCGATCCAAGAGTCCAGGCGCGGCTGGCGGGTGTTGTGCTGCTGCAGGCCGACGTGAC
ACGCAATACTGCCGACGATCGCATCTTGCTCAAACGCTTCGGCTTGTTCGGCCCACCCGGCATCATCTTGTACGGTGCCG
ACGGGCGTGAGAGCCCGGTGCGGGTGATCGGCTTCCAGTCTGCAAGCCTTTTCCTCGACAGTCTCGCGAAAGCCTTCGGT
GACGACGGGAAGCGTTGA

Upstream 100 bases:

>100_bases
CTCACATGCCCGTGTGACCCGCGAGACGTGAGGGCATCCGCCGAGAGGCGATAGCGCGATCAGCACGGTGTGGTCGGTCA
TTGAGGTCAGGGAGTGCGGT

Downstream 100 bases:

>100_bases
GAACTACCTGGCCCGCCCGCAGCTTATTCAGCGGTATCGCCACTGGGTTCCAGATGCTGTTGGCTGGGTGGCCAGTCTTT
ATGGACACCGCCTCTGAATG

Product: Protein-disulfide reductase

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MGWSVAATRTGGGGRVRGVAPAQLVLLLLAALWFCVTGTGGVAHAAGEQDLLPPEQAFRFAARQLEDRSIEVHFDIADGY
HLYRERFAFAAQPAGVKLGTPEFPPGQVNFDEALGKQMETYHGGVTIRVPVAVAQVDGKWLLTVTSQGCADKGVCYPPMH
SVYKVGGGSLGGLFDKHRSSTPMTSPAPPATPTLPSLGGGQIGPAVPSAAPRNDDGDHIARVLASRQLGKIVTVFLGFGL
LLTLTPSALAMVLILSSIVVGEHVTRVRALLVSFAYVLGTAVGVGAAAELLGERLSARLQAPWALGAFAALAVALALSMF
GLYELGRQLPTTAPSNRWSGGRIAVAAASGVISTLVVVRSVPVPLSSTLAYLKQTGDAIGSGGALFGLAIGMGVTLVLVG
VATGYLLPRAGHWLMVTKRFLGFLLLGEALWAVSPLLPPWALMAAWAMLLLIAAAFLGAFDSLGPEPRSMARLGKGMGMV
AALAGAILLVGLASGGRDLLQPLSHLRAGPMAPASTAGPALVRFERIRSVAELDARLVQAAAAGKPVLLDFYADWCVSCK
EMERLTFSDPRVQARLAGVVLLQADVTRNTADDRILLKRFGLFGPPGIILYGADGRESPVRVIGFQSASLFLDSLAKAFG
DDGKR

Sequences:

>Translated_645_residues
MGWSVAATRTGGGGRVRGVAPAQLVLLLLAALWFCVTGTGGVAHAAGEQDLLPPEQAFRFAARQLEDRSIEVHFDIADGY
HLYRERFAFAAQPAGVKLGTPEFPPGQVNFDEALGKQMETYHGGVTIRVPVAVAQVDGKWLLTVTSQGCADKGVCYPPMH
SVYKVGGGSLGGLFDKHRSSTPMTSPAPPATPTLPSLGGGQIGPAVPSAAPRNDDGDHIARVLASRQLGKIVTVFLGFGL
LLTLTPSALAMVLILSSIVVGEHVTRVRALLVSFAYVLGTAVGVGAAAELLGERLSARLQAPWALGAFAALAVALALSMF
GLYELGRQLPTTAPSNRWSGGRIAVAAASGVISTLVVVRSVPVPLSSTLAYLKQTGDAIGSGGALFGLAIGMGVTLVLVG
VATGYLLPRAGHWLMVTKRFLGFLLLGEALWAVSPLLPPWALMAAWAMLLLIAAAFLGAFDSLGPEPRSMARLGKGMGMV
AALAGAILLVGLASGGRDLLQPLSHLRAGPMAPASTAGPALVRFERIRSVAELDARLVQAAAAGKPVLLDFYADWCVSCK
EMERLTFSDPRVQARLAGVVLLQADVTRNTADDRILLKRFGLFGPPGIILYGADGRESPVRVIGFQSASLFLDSLAKAFG
DDGKR
>Mature_644_residues
GWSVAATRTGGGGRVRGVAPAQLVLLLLAALWFCVTGTGGVAHAAGEQDLLPPEQAFRFAARQLEDRSIEVHFDIADGYH
LYRERFAFAAQPAGVKLGTPEFPPGQVNFDEALGKQMETYHGGVTIRVPVAVAQVDGKWLLTVTSQGCADKGVCYPPMHS
VYKVGGGSLGGLFDKHRSSTPMTSPAPPATPTLPSLGGGQIGPAVPSAAPRNDDGDHIARVLASRQLGKIVTVFLGFGLL
LTLTPSALAMVLILSSIVVGEHVTRVRALLVSFAYVLGTAVGVGAAAELLGERLSARLQAPWALGAFAALAVALALSMFG
LYELGRQLPTTAPSNRWSGGRIAVAAASGVISTLVVVRSVPVPLSSTLAYLKQTGDAIGSGGALFGLAIGMGVTLVLVGV
ATGYLLPRAGHWLMVTKRFLGFLLLGEALWAVSPLLPPWALMAAWAMLLLIAAAFLGAFDSLGPEPRSMARLGKGMGMVA
ALAGAILLVGLASGGRDLLQPLSHLRAGPMAPASTAGPALVRFERIRSVAELDARLVQAAAAGKPVLLDFYADWCVSCKE
MERLTFSDPRVQARLAGVVLLQADVTRNTADDRILLKRFGLFGPPGIILYGADGRESPVRVIGFQSASLFLDSLAKAFGD
DGKR

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=628, Percent_Identity=33.5987261146497, Blast_Score=258, Evalue=7e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 67252; Mature: 67121

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWSVAATRTGGGGRVRGVAPAQLVLLLLAALWFCVTGTGGVAHAAGEQDLLPPEQAFRF
CCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
AARQLEDRSIEVHFDIADGYHLYRERFAFAAQPAGVKLGTPEFPPGQVNFDEALGKQMET
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
YHGGVTIRVPVAVAQVDGKWLLTVTSQGCADKGVCYPPMHSVYKVGGGSLGGLFDKHRSS
HCCCEEEEEEEEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHCCC
TPMTSPAPPATPTLPSLGGGQIGPAVPSAAPRNDDGDHIARVLASRQLGKIVTVFLGFGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLTLTPSALAMVLILSSIVVGEHVTRVRALLVSFAYVLGTAVGVGAAAELLGERLSARLQ
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APWALGAFAALAVALALSMFGLYELGRQLPTTAPSNRWSGGRIAVAAASGVISTLVVVRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHC
VPVPLSSTLAYLKQTGDAIGSGGALFGLAIGMGVTLVLVGVATGYLLPRAGHWLMVTKRF
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LGFLLLGEALWAVSPLLPPWALMAAWAMLLLIAAAFLGAFDSLGPEPRSMARLGKGMGMV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHH
AALAGAILLVGLASGGRDLLQPLSHLRAGPMAPASTAGPALVRFERIRSVAELDARLVQA
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAAGKPVLLDFYADWCVSCKEMERLTFSDPRVQARLAGVVLLQADVTRNTADDRILLKRF
HHCCCCEEEHHHHHHHHCHHHHHHCCCCCCHHHHHHHEEEEEEECCCCCCCCHHHHHHHC
GLFGPPGIILYGADGRESPVRVIGFQSASLFLDSLAKAFGDDGKR
CCCCCCCEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GWSVAATRTGGGGRVRGVAPAQLVLLLLAALWFCVTGTGGVAHAAGEQDLLPPEQAFRF
CCEEEEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
AARQLEDRSIEVHFDIADGYHLYRERFAFAAQPAGVKLGTPEFPPGQVNFDEALGKQMET
HHHHHCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
YHGGVTIRVPVAVAQVDGKWLLTVTSQGCADKGVCYPPMHSVYKVGGGSLGGLFDKHRSS
HCCCEEEEEEEEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHCCC
TPMTSPAPPATPTLPSLGGGQIGPAVPSAAPRNDDGDHIARVLASRQLGKIVTVFLGFGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLTLTPSALAMVLILSSIVVGEHVTRVRALLVSFAYVLGTAVGVGAAAELLGERLSARLQ
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
APWALGAFAALAVALALSMFGLYELGRQLPTTAPSNRWSGGRIAVAAASGVISTLVVVRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHC
VPVPLSSTLAYLKQTGDAIGSGGALFGLAIGMGVTLVLVGVATGYLLPRAGHWLMVTKRF
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LGFLLLGEALWAVSPLLPPWALMAAWAMLLLIAAAFLGAFDSLGPEPRSMARLGKGMGMV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHH
AALAGAILLVGLASGGRDLLQPLSHLRAGPMAPASTAGPALVRFERIRSVAELDARLVQA
HHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AAAGKPVLLDFYADWCVSCKEMERLTFSDPRVQARLAGVVLLQADVTRNTADDRILLKRF
HHCCCCEEEHHHHHHHHCHHHHHHCCCCCCHHHHHHHEEEEEEECCCCCCCCHHHHHHHC
GLFGPPGIILYGADGRESPVRVIGFQSASLFLDSLAKAFGDDGKR
CCCCCCCEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]