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The map label for this gene is czcD [H]

Identifier: 187928844

GI number: 187928844

Start: 1857739

End: 1858689

Strand: Reverse

Name: czcD [H]

Synonym: Rpic_1761

Alternate gene names: 187928844

Gene position: 1858689-1857739 (Counterclockwise)

Preceding gene: 187928845

Following gene: 187928843

Centisome position: 47.14

GC content: 57.83

Gene sequence:

>951_bases
ATGGGCGCAGGTCACTCACACGACCATCCCGGTGGCAACGAGCGATCGCTCAAGATCGCCCTTGCGCTGACCGGTACGTT
CCTGATTGCCGAAGTGGTCGGTGGTGTCATGACGAAGAGCCTGGCGTTGATCTCCGACGCCGCGCACATGCTCACGGACA
CCGTCGCACTGGCCATCGCACTGGCTGCTATTGCGATCGCCAAGCGACCCGCGGACAAGAAGCGGACATTTGGCTACTAC
CGTTTTGAGATTCTTGCCGCGGCCTTTAACGCATTGCTGCTGTTCGGTGTGGCTATCTACATCCTGTACGAAGCCTACCT
GCGGCTGAAATCGCCACCTCAGATTGAGTCAACCGGCATGTTCGTCGTGGCTGTGCTGGGCCTGATCATCAATCTCATCA
GCATGCGCATGCTGTCCTCCGGGCAAAGCAGCAGCCTGAACGTGAAGGGTGCTTATCTGGAAGTCTGGAGCGATCTGCTC
GGGTCGGTTGGCGTCATCGCCGGTGCGATCATCATCCGCTTCACGGGCTGGGCGTGGGTCGACTCCGCCATTGCGGTGCT
GATCGGCCTCTGGGTACTGCCTCGCACGTGGATCCTGCTGAAGTCGAGCCTGAATGTGCTGCTCGAAGGCGTACCCGATG
ACGTGGATCTGGCAGAGGTTGAGAAGCAAATTCTGGCGACGCCCGGGGTAAAAAGCTTCCATGACCTCCACATCTGGGCA
CTTACCAGCGGCAAGGCGAGCTTGACGGTTCATGTCGTGAATGACACGGCCGTCAACCCGGAAATGGAAGTGCTACCGGA
ATTGAAGCAGATGCTGGCTGACAAATTCGATATCACGCACGTGACCATTCAGTTCGAACTGGCACCATGCGAACAAGCGG
ATGCAGCTCAGCATTTCAATGCATCGCCAGCACTGGTCGGATCGAAGTCGCTTGCTGCAGGAGGAAACTAA

Upstream 100 bases:

>100_bases
AGCCAGTCACTCAGACGCATCAACCGGATCAAGGCCGCCAGCCTGCATGACGTAAATCCTTGGGCGGTCATCGTACCGCC
CAATTTTTATAGGAGTTTCT

Downstream 100 bases:

>100_bases
GGTGCGGGTACTTGTTGTAGAAGACGAACCGCGTACTGCGGAGTATTTGCAGAAGGGATTGTCGGAGTCGGGTTTCGTGG
TCGACATCGCGAACAATGGT

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGAGHSHDHPGGNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYY
RFEILAAAFNALLLFGVAIYILYEAYLRLKSPPQIESTGMFVVAVLGLIINLISMRMLSSGQSSSLNVKGAYLEVWSDLL
GSVGVIAGAIIIRFTGWAWVDSAIAVLIGLWVLPRTWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWA
LTSGKASLTVHVVNDTAVNPEMEVLPELKQMLADKFDITHVTIQFELAPCEQADAAQHFNASPALVGSKSLAAGGN

Sequences:

>Translated_316_residues
MGAGHSHDHPGGNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYY
RFEILAAAFNALLLFGVAIYILYEAYLRLKSPPQIESTGMFVVAVLGLIINLISMRMLSSGQSSSLNVKGAYLEVWSDLL
GSVGVIAGAIIIRFTGWAWVDSAIAVLIGLWVLPRTWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWA
LTSGKASLTVHVVNDTAVNPEMEVLPELKQMLADKFDITHVTIQFELAPCEQADAAQHFNASPALVGSKSLAAGGN
>Mature_315_residues
GAGHSHDHPGGNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIALAAIAIAKRPADKKRTFGYYR
FEILAAAFNALLLFGVAIYILYEAYLRLKSPPQIESTGMFVVAVLGLIINLISMRMLSSGQSSSLNVKGAYLEVWSDLLG
SVGVIAGAIIIRFTGWAWVDSAIAVLIGLWVLPRTWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWAL
TSGKASLTVHVVNDTAVNPEMEVLPELKQMLADKFDITHVTIQFELAPCEQADAAQHFNASPALVGSKSLAAGGN

Specific function: Necessary for activation of the czc determinant [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=297, Percent_Identity=34.3434343434343, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI21361112, Length=299, Percent_Identity=31.7725752508361, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI289803013, Length=322, Percent_Identity=32.2981366459627, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI289803009, Length=322, Percent_Identity=32.2981366459627, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI289803007, Length=322, Percent_Identity=32.2981366459627, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI289803003, Length=322, Percent_Identity=32.2981366459627, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI64762489, Length=322, Percent_Identity=32.2981366459627, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI21359890, Length=300, Percent_Identity=30.6666666666667, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI20070323, Length=319, Percent_Identity=29.153605015674, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI14210520, Length=218, Percent_Identity=31.1926605504587, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI52351208, Length=126, Percent_Identity=38.0952380952381, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI222080086, Length=121, Percent_Identity=34.7107438016529, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI40255009, Length=121, Percent_Identity=34.7107438016529, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI52352803, Length=127, Percent_Identity=40.1574803149606, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786966, Length=293, Percent_Identity=40.6143344709898, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI193210990, Length=313, Percent_Identity=32.9073482428115, Blast_Score=169, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17555794, Length=323, Percent_Identity=30.3405572755418, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17555796, Length=310, Percent_Identity=30.3225806451613, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32564488, Length=299, Percent_Identity=32.4414715719064, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17550442, Length=125, Percent_Identity=33.6, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17550440, Length=125, Percent_Identity=33.6, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320411, Length=242, Percent_Identity=33.0578512396694, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323899, Length=138, Percent_Identity=38.4057971014493, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324892, Length=120, Percent_Identity=40, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583858, Length=312, Percent_Identity=29.8076923076923, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24656728, Length=343, Percent_Identity=25.9475218658892, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656724, Length=343, Percent_Identity=25.9475218658892, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656720, Length=343, Percent_Identity=25.9475218658892, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656715, Length=343, Percent_Identity=25.9475218658892, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357035, Length=343, Percent_Identity=25.9475218658892, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24645863, Length=123, Percent_Identity=42.2764227642276, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24584409, Length=121, Percent_Identity=37.1900826446281, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574430, Length=121, Percent_Identity=37.1900826446281, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24585900, Length=121, Percent_Identity=34.7107438016529, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24585898, Length=121, Percent_Identity=34.7107438016529, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24585896, Length=121, Percent_Identity=34.7107438016529, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19921672, Length=121, Percent_Identity=34.7107438016529, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 33708; Mature: 33577

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGHSHDHPGGNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIA
CCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIAIAKRPADKKRTFGYYRFEILAAAFNALLLFGVAIYILYEAYLRLKSPPQIESTGM
HHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
FVVAVLGLIINLISMRMLSSGQSSSLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAWV
HHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DSAIAVLIGLWVLPRTWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEE
LTSGKASLTVHVVNDTAVNPEMEVLPELKQMLADKFDITHVTIQFELAPCEQADAAQHFN
EECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHCC
ASPALVGSKSLAAGGN
CCCCEECCCCCCCCCC
>Mature Secondary Structure 
GAGHSHDHPGGNERSLKIALALTGTFLIAEVVGGVMTKSLALISDAAHMLTDTVALAIA
CCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAIAIAKRPADKKRTFGYYRFEILAAAFNALLLFGVAIYILYEAYLRLKSPPQIESTGM
HHHHHHHCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
FVVAVLGLIINLISMRMLSSGQSSSLNVKGAYLEVWSDLLGSVGVIAGAIIIRFTGWAWV
HHHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DSAIAVLIGLWVLPRTWILLKSSLNVLLEGVPDDVDLAEVEKQILATPGVKSFHDLHIWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEE
LTSGKASLTVHVVNDTAVNPEMEVLPELKQMLADKFDITHVTIQFELAPCEQADAAQHFN
EECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHCC
ASPALVGSKSLAAGGN
CCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]