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The map label for this gene is glpE [C]

Identifier: 187927742

GI number: 187927742

Start: 686681

End: 687013

Strand: Reverse

Name: glpE [C]

Synonym: Rpic_0646

Alternate gene names: 187927742

Gene position: 687013-686681 (Counterclockwise)

Preceding gene: 187927743

Following gene: 187927741

Centisome position: 17.43

GC content: 64.86

Gene sequence:

>333_bases
ATGCAGCAGCTCGCTCCCACCGCCCTCGCCCAATGGCTCGCCGACGCATCGCGCGCGAAGCCCGTCCTGCTCGACGTGCG
CTGGACGGAGGAGGTGGAAATCTGTGCCATTCCTGGCATCACGCACATTCCGATGGACCAGATCCCGGGGCGTGCCAGCG
AGCTGAATGCTGACCAAGACATCGTCTGCATCTGCCACCACGGCGGACGCAGTGCGCAGGTTGCGCAGTATCTGATCACG
CAAGGCGGCTTTGATGCCGCGCGTGTCTACAACCTGCAAGGCGGCGTCCACGCCTGGGCTCACCAGGTGGACCCGCAGAT
GGCGACGTACTGA

Upstream 100 bases:

>100_bases
TATCAGACGCGCAACCTGTTCGAGACGTATGTGACGCCGCTGGTGGGTGTTCCCGCGCCGTCGTCCTTCCGCTTCTGATC
CCTCTCGCCCCCCAATCATC

Downstream 100 bases:

>100_bases
TTGGGGAAGCCGCCGCCGGGCAAAGCCCTGTTCACGCTCCACAGGCACTGAACAGGGCCTGACGCGCCCGCGCTGCCTTC
CGAACGCGAACGTTTCCTCC

Product: Rhodanese domain-containing protein

Products: H+; Sulfite; Thiocyanate [C]

Alternate protein names: Rhodanese Domain-Containing Protein; Rhodanese-Like Protein; Rhodanese-Related Sulfurtransferase; Rhodanese-Like Domain-Containing Protein; Thiosulfate Sulfurtransferase; Molybdopterin Biosynthesis MoeB Protein; Sulfurylase; MoeZ/MoeB Domain Family; Glutaredoxin-Like Protein; Thiosulfate Sulfurtransferase GlpE; Sulfurtransferase Protein; Molybdopterin-Synthase Sulfurylase; Molybdopterin/Thiamine Biosynthesis Family Protein; Rhodanese Family Protein; Rhodanese-Like Domain; Sulfate Permease Andrelated Transporter; Thiosulfate Sulfurtransferase Rhodanese-Like Domain

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MQQLAPTALAQWLADASRAKPVLLDVRWTEEVEICAIPGITHIPMDQIPGRASELNADQDIVCICHHGGRSAQVAQYLIT
QGGFDAARVYNLQGGVHAWAHQVDPQMATY

Sequences:

>Translated_110_residues
MQQLAPTALAQWLADASRAKPVLLDVRWTEEVEICAIPGITHIPMDQIPGRASELNADQDIVCICHHGGRSAQVAQYLIT
QGGFDAARVYNLQGGVHAWAHQVDPQMATY
>Mature_110_residues
MQQLAPTALAQWLADASRAKPVLLDVRWTEEVEICAIPGITHIPMDQIPGRASELNADQDIVCICHHGGRSAQVAQYLIT
QGGFDAARVYNLQGGVHAWAHQVDPQMATY

Specific function: Catalyzes, Although With Low Efficiency, The Sulfur Transfer Reaction From Thiosulfate To Cyanide. The Relatively Low Affinity Of Glpe For Both Thiosulfate And Cyanide Suggests That These Compounds Are Not The Physiological Substrates. Thioredoxin 1 Or Re

COG id: COG0607

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.8.1.1 [C]

Molecular weight: Translated: 12018; Mature: 12018

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLAPTALAQWLADASRAKPVLLDVRWTEEVEICAIPGITHIPMDQIPGRASELNADQD
CCCCCHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCCCCCCCHHHCCCCCHHCCCCCC
IVCICHHGGRSAQVAQYLITQGGFDAARVYNLQGGVHAWAHQVDPQMATY
EEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQQLAPTALAQWLADASRAKPVLLDVRWTEEVEICAIPGITHIPMDQIPGRASELNADQD
CCCCCHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCCCCCCCHHHCCCCCHHCCCCCC
IVCICHHGGRSAQVAQYLITQGGFDAARVYNLQGGVHAWAHQVDPQMATY
EEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cyanide; Thiosulfate [C]

Specific reaction: Cyanide + Thiosulfate --> H+ + Sulfite + Thiocyanate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA