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The map label for this gene is moaC

Identifier: 187927581

GI number: 187927581

Start: 514604

End: 515080

Strand: Reverse

Name: moaC

Synonym: Rpic_0481

Alternate gene names: 187927581

Gene position: 515080-514604 (Counterclockwise)

Preceding gene: 187927583

Following gene: 187927570

Centisome position: 13.06

GC content: 61.43

Gene sequence:

>477_bases
ATGTCGCAACTCACCCACTTCGATTCCGCCGGACAAGCCCATATGGTCGATGTCGGCGACAAGGCCGTCACACACCGCGT
GGCCGTCGCCACCGGCACGATCCGCATGCTGCCCGAGACGTTTGCGCTGGTGCGCGATGGCAACGCCAAGAAAGGCGATG
TGCTGGGGATTGCGCGCGTTGCCGCCATCCAAGGCTCAAAGCGGACGTCGGATTTGATTCCGTTGTGCCATCCGCTGGCG
TTGACGAAGGTGGCGGTGGAGTTTGAGCTGAATGAGGCTGGGCACAGCGTCCGTTGCACCGTTCGTGCGGAAACGCGTGG
GCAAACCGGCGTGGAAATGGAAGCGCTAACCGCCGTGCAGGTGGGGCTGCTGACGATTTACGATATGTGTAAGGCTGTCG
ATCGGGGGATGGTGATTGGGGATGTGCGGTTGATGGAGAAGCGAGGGGGGAAGTCGGGGGATTGGGTGGCTGATTAG

Upstream 100 bases:

>100_bases
AAGCACGGAGAGCGGAATCAGCGCGGCAACATCGCCGCAAGCTGGGTGCTTGCTATCATAAAACGCTTCGTACCCCGCCC
CGCAAAACGCGCTGTCACTC

Downstream 100 bases:

>100_bases
AAAGAACAGAGAGCGCCGTCGGCGCTCTCATCATTTGGCGCTTAAATTACCGGCATTCCGCAGGTGCAACATTTGTCGCC
AATGACGGCTTCGTTTCAAG

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MSQLTHFDSAGQAHMVDVGDKAVTHRVAVATGTIRMLPETFALVRDGNAKKGDVLGIARVAAIQGSKRTSDLIPLCHPLA
LTKVAVEFELNEAGHSVRCTVRAETRGQTGVEMEALTAVQVGLLTIYDMCKAVDRGMVIGDVRLMEKRGGKSGDWVAD

Sequences:

>Translated_158_residues
MSQLTHFDSAGQAHMVDVGDKAVTHRVAVATGTIRMLPETFALVRDGNAKKGDVLGIARVAAIQGSKRTSDLIPLCHPLA
LTKVAVEFELNEAGHSVRCTVRAETRGQTGVEMEALTAVQVGLLTIYDMCKAVDRGMVIGDVRLMEKRGGKSGDWVAD
>Mature_157_residues
SQLTHFDSAGQAHMVDVGDKAVTHRVAVATGTIRMLPETFALVRDGNAKKGDVLGIARVAAIQGSKRTSDLIPLCHPLAL
TKVAVEFELNEAGHSVRCTVRAETRGQTGVEMEALTAVQVGLLTIYDMCKAVDRGMVIGDVRLMEKRGGKSGDWVAD

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=57.4193548387097, Blast_Score=171, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=44.9664429530201, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574490, Length=150, Percent_Identity=51.3333333333333, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=50.3649635036496, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_RALPJ (B2UGE9)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001898068.1
- ProteinModelPortal:   B2UGE9
- SMR:   B2UGE9
- GeneID:   6289116
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_0481
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- ProtClustDB:   PRK09364
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 16887; Mature: 16756

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLTHFDSAGQAHMVDVGDKAVTHRVAVATGTIRMLPETFALVRDGNAKKGDVLGIARV
CCCCCCCCCCCCEEEEECCCHHHHEEEEEECCCEEECHHHEEEEECCCCCCCCCHHHHHH
AAIQGSKRTSDLIPLCHPLALTKVAVEFELNEAGHSVRCTVRAETRGQTGVEMEALTAVQ
HHHCCCCCCCCCCCHHHHHHHEEEEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHH
VGLLTIYDMCKAVDRGMVIGDVRLMEKRGGKSGDWVAD
HHHHHHHHHHHHHHCCEEEEHEEEEHHCCCCCCCCCCC
>Mature Secondary Structure 
SQLTHFDSAGQAHMVDVGDKAVTHRVAVATGTIRMLPETFALVRDGNAKKGDVLGIARV
CCCCCCCCCCCEEEEECCCHHHHEEEEEECCCEEECHHHEEEEECCCCCCCCCHHHHHH
AAIQGSKRTSDLIPLCHPLALTKVAVEFELNEAGHSVRCTVRAETRGQTGVEMEALTAVQ
HHHCCCCCCCCCCCHHHHHHHEEEEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHH
VGLLTIYDMCKAVDRGMVIGDVRLMEKRGGKSGDWVAD
HHHHHHHHHHHHHHCCEEEEHEEEEHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA