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The map label for this gene is 187927548

Identifier: 187927548

GI number: 187927548

Start: 480605

End: 481912

Strand: Direct

Name: 187927548

Synonym: Rpic_0448

Alternate gene names: NA

Gene position: 480605-481912 (Clockwise)

Preceding gene: 187927547

Following gene: 187927549

Centisome position: 12.19

GC content: 50.69

Gene sequence:

>1308_bases
ATGAACAATAAGGACATGGGCGCGATGAGCGAACAGAACAACCCAAAGCGGGCGCTGGTGCCACGGCTGCGGTTTCCTGA
GTTTCAAGATGCAGGGAACTGGAAAACCGAAGCTCTTCGGAAATTGGCGAAGCGATGCGCCAAAAAGAACTCCGAAGGCG
AACACAAGCGTGTGCTGACCAATTCAGCCGAGTATGGGGTGATCGATCAACGCGACTACTTCGACAAAGACATTGCCAAT
CAGGGGAATCTGGAGGGCTATTACATCGTTGAAAAAGGGGACTACGTATATAACCCTCGCATTTCAGCGAGCGCCCCAGT
TGGGCCGATTTCAAAGAACAATGTCGGCACTGGGGTGATGTCTCCCTTATATACCGTCTTCAGGTTTATCAGTAGTGAGA
ACGATTTCTTTGCTCACTACTTTAAATCGCCGCATTGGCATCATTACATGCGCCAAGCTTCGAGTACTGGCGCAAGACAT
GACCGCATGAGCATCACGAATGATGACTTCATGAACATGCCGCTCCCCGTCTCCGTGCCGAAGGAACAACAAAAGATCGC
CGACAGCTTGTCTTCCCTCGACGAGCTAATCATGGCGGAAAACCGGAAACTTGGCACCCTCAAGGTCTACAAGAATGGCT
TGATGCAGCAGCTGTTCCCCCGCGAAGGCGAAACTGTTCCCCGCCTGCGGCTCCCTGGGTTCCGACGTGATCCTCAATGG
ATTTCAGCCACGCTGGGGGATATCGCGAACGTTCAATCTGGTGGCACGCCGGCGCGCACCAACCCTGCGTATTGGAACGG
GGATATTCCTTGGGTGACTACTTCACTTATTGATTCGAGCACTATCCTCAAGGCGGATGAATATATTACCAAGGCCGGTC
TTGAAGAGTCGTCAGCAAAAATCTTCCCAAAGGGTACCCTATTGATGGCTATGTACGGGCAGGGAAGGACGCGGGGTAGA
GTTTCGGTGCTTGGAATAGATGCCGCCACAAACCAGGCTTGCGCTGCAATTATTTTGAAGAGGCGCGGGATTTCGACAGA
TTTCGTTTTTCAGAATTTGGCCTCAAGATACGAAGAAATACGAAAGATCAGTAATTCAGGTGGGCAGGAAAATTTAAGTG
CTGGACTTATCGAAGGAATTTCATTTTCATTCCCAGATAACGAAAGCGAACAAGAATATATCGCTAACACCTTGTCTTCG
ATCGATGGGTTGATCACTACTCAACGCCAGAAGATCGACGCCCTTGAGATCCACAAGAAGGGCTTGATGCAGCAGCTTTT
CCCGGTCATGGCTGAGGCGCTGGCATGA

Upstream 100 bases:

>100_bases
TGGAAGGCGCGTACGCAGAAGGAGTTGGCGCTGGTGGAAGACCTGACGCCGCTACTGCACAAGCTCGCTCAGGGGCGCGA
GATTTCGGGGCTGAGTGCGT

Downstream 100 bases:

>100_bases
AACCGGGCCAAGCTTTCACCGACCTGCCCGCGTTGGCCGCGCAGCTGCGGCAGGAACTGGAGAACAAGAAAACCATCCTG
CTCTACGCCTACAATGGCAC

Product: restriction modification system DNA specificity domain-containing protein

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MNNKDMGAMSEQNNPKRALVPRLRFPEFQDAGNWKTEALRKLAKRCAKKNSEGEHKRVLTNSAEYGVIDQRDYFDKDIAN
QGNLEGYYIVEKGDYVYNPRISASAPVGPISKNNVGTGVMSPLYTVFRFISSENDFFAHYFKSPHWHHYMRQASSTGARH
DRMSITNDDFMNMPLPVSVPKEQQKIADSLSSLDELIMAENRKLGTLKVYKNGLMQQLFPREGETVPRLRLPGFRRDPQW
ISATLGDIANVQSGGTPARTNPAYWNGDIPWVTTSLIDSSTILKADEYITKAGLEESSAKIFPKGTLLMAMYGQGRTRGR
VSVLGIDAATNQACAAIILKRRGISTDFVFQNLASRYEEIRKISNSGGQENLSAGLIEGISFSFPDNESEQEYIANTLSS
IDGLITTQRQKIDALEIHKKGLMQQLFPVMAEALA

Sequences:

>Translated_435_residues
MNNKDMGAMSEQNNPKRALVPRLRFPEFQDAGNWKTEALRKLAKRCAKKNSEGEHKRVLTNSAEYGVIDQRDYFDKDIAN
QGNLEGYYIVEKGDYVYNPRISASAPVGPISKNNVGTGVMSPLYTVFRFISSENDFFAHYFKSPHWHHYMRQASSTGARH
DRMSITNDDFMNMPLPVSVPKEQQKIADSLSSLDELIMAENRKLGTLKVYKNGLMQQLFPREGETVPRLRLPGFRRDPQW
ISATLGDIANVQSGGTPARTNPAYWNGDIPWVTTSLIDSSTILKADEYITKAGLEESSAKIFPKGTLLMAMYGQGRTRGR
VSVLGIDAATNQACAAIILKRRGISTDFVFQNLASRYEEIRKISNSGGQENLSAGLIEGISFSFPDNESEQEYIANTLSS
IDGLITTQRQKIDALEIHKKGLMQQLFPVMAEALA
>Mature_435_residues
MNNKDMGAMSEQNNPKRALVPRLRFPEFQDAGNWKTEALRKLAKRCAKKNSEGEHKRVLTNSAEYGVIDQRDYFDKDIAN
QGNLEGYYIVEKGDYVYNPRISASAPVGPISKNNVGTGVMSPLYTVFRFISSENDFFAHYFKSPHWHHYMRQASSTGARH
DRMSITNDDFMNMPLPVSVPKEQQKIADSLSSLDELIMAENRKLGTLKVYKNGLMQQLFPREGETVPRLRLPGFRRDPQW
ISATLGDIANVQSGGTPARTNPAYWNGDIPWVTTSLIDSSTILKADEYITKAGLEESSAKIFPKGTLLMAMYGQGRTRGR
VSVLGIDAATNQACAAIILKRRGISTDFVFQNLASRYEEIRKISNSGGQENLSAGLIEGISFSFPDNESEQEYIANTLSS
IDGLITTQRQKIDALEIHKKGLMQQLFPVMAEALA

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 48623; Mature: 48623

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKDMGAMSEQNNPKRALVPRLRFPEFQDAGNWKTEALRKLAKRCAKKNSEGEHKRVLT
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHC
NSAEYGVIDQRDYFDKDIANQGNLEGYYIVEKGDYVYNPRISASAPVGPISKNNVGTGVM
CCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCHHH
SPLYTVFRFISSENDFFAHYFKSPHWHHYMRQASSTGARHDRMSITNDDFMNMPLPVSVP
HHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
KEQQKIADSLSSLDELIMAENRKLGTLKVYKNGLMQQLFPREGETVPRLRLPGFRRDPQW
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
ISATLGDIANVQSGGTPARTNPAYWNGDIPWVTTSLIDSSTILKADEYITKAGLEESSAK
HHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEHHHHCCCHHHHHHHHHHHHCCCCCCCE
IFPKGTLLMAMYGQGRTRGRVSVLGIDAATNQACAAIILKRRGISTDFVFQNLASRYEEI
ECCCCEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RKISNSGGQENLSAGLIEGISFSFPDNESEQEYIANTLSSIDGLITTQRQKIDALEIHKK
HHHHCCCCHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMQQLFPVMAEALA
HHHHHHHHHHHHHHC
>Mature Secondary Structure
MNNKDMGAMSEQNNPKRALVPRLRFPEFQDAGNWKTEALRKLAKRCAKKNSEGEHKRVLT
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHC
NSAEYGVIDQRDYFDKDIANQGNLEGYYIVEKGDYVYNPRISASAPVGPISKNNVGTGVM
CCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCEEECCCCCCCCCCCCCCCCCCCCHHH
SPLYTVFRFISSENDFFAHYFKSPHWHHYMRQASSTGARHDRMSITNDDFMNMPLPVSVP
HHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
KEQQKIADSLSSLDELIMAENRKLGTLKVYKNGLMQQLFPREGETVPRLRLPGFRRDPQW
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHH
ISATLGDIANVQSGGTPARTNPAYWNGDIPWVTTSLIDSSTILKADEYITKAGLEESSAK
HHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEHHHHCCCHHHHHHHHHHHHCCCCCCCE
IFPKGTLLMAMYGQGRTRGRVSVLGIDAATNQACAAIILKRRGISTDFVFQNLASRYEEI
ECCCCEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RKISNSGGQENLSAGLIEGISFSFPDNESEQEYIANTLSSIDGLITTQRQKIDALEIHKK
HHHHCCCCHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLMQQLFPVMAEALA
HHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]