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The map label for this gene is 187927429

Identifier: 187927429

GI number: 187927429

Start: 343516

End: 344433

Strand: Direct

Name: 187927429

Synonym: Rpic_0326

Alternate gene names: NA

Gene position: 343516-344433 (Clockwise)

Preceding gene: 187927425

Following gene: 187927430

Centisome position: 8.71

GC content: 66.01

Gene sequence:

>918_bases
ATGAACACCCCGTCGTCTTCCTCCGGGCGTGCCGGGCGCGCGCGCCGGGGCCGCAAAGTCTGGTCCGGCACGCAGCACGT
CATCGCCTACGGCATGCCGCCGCTGGGCTGGCGCGACCTCTATCACCACGCGCTGGAGGTCAACTGGCCGACCTTCTTTG
CGTTGCTGGCCACGTTGTTCCTGGCGCTCAATGCCGTATTCGCGGGGCTGTATTCGCTCGGCGACGGCGCGATCGCGAAC
CAGTCGCCGCCGGGTTTCGTGGGGGCGTTCTTCTTCAGCGTCGAGACCCTGGCCACCGTCGGCTACGGCGACATGCACCC
GCAAACGCTCTACGCCCACGTCATCGCCACGCTGGAGATCTTCATCGGCATGTCGGGCATTGCCATGGCGACGGGCCTGG
TGTTTGCCCGCTTCTCTCGCCCGCGCGCCAAGATCATGTTTGCGCGCAACGTTGTTGTGCGGCCGCTCAACGGCAAATCC
ACGCTGATGCTGCGCGCCGCCAATGCGCGCCAGAACGTCATCGCCGAGGCCACCGCCCGGCTGCGCCTGATGCAGGACGA
GGTCTCGCCCGAGGGCTACGCGATCTACAAGATCCACGACCTGAAACTTGAGCGCAGCGAGCACCCGATCTTCCTGCTGG
GCTGGGTGATGATGCATGTCATCGATGAAGCCAGCCCGCTGCACGGCGCCACCGCGGAATCGCTTGCGGCGGGTGATGCC
TTGCTGCTGCTGACCATCGAGGGCGCCGACGAGACCGCCGCGCAGACCGTGCAGGCACGCTATTCCTGGCGGCACGACGA
GATCCGCTGGAACCATCGCTATGCCGACCTCATCCGCGACGAGAGCGGCGTCACATCGGTCGACTACGACAACTTCCACC
TGATCCACCCGATCGAGACGCCCCCGCAGGCACAATGA

Upstream 100 bases:

>100_bases
CACGCGGCGCCTGGCCCGCCTTGCCGGACTGGCGTGCCGGTCGGTACACTGCCCCGGCCGTACCCGGGCGGGCACGGCGC
ATCATCGGCGAGAGGCCTCC

Downstream 100 bases:

>100_bases
CCGGCTTGTCCGATCCCAACGCGCAACCCCCGTGGCCCTGAATCTCGTCTGGCTCGCCTTCTTTCTCGTCGCCTTCGTTA
CCGCATGCGTGCAGGTGGTG

Product: K channel inward rectifier conserved region 2 domain-containing protein

Products: NA

Alternate protein names: Ion Transport 2 Domain-Containing Protein; K+ Channel Inward Rectifier; Inward Rectifier Potassium Channel; Inward Rectifier Potassium Channel Protein; Inward Rectifier Potassium Channel Superfamily; TrkA-N Family Protein; ATP-Sensitive Potassium Transporter; Potassium Channel Protein; Inward Rectifier Potassium Channel Irk; ATP-Sensitive Inward Rectifier Potassium Channel; K+ Channel Inward Rectifier Protein; K+ Channel Protein; ATP-Sensitive Potassium Channel Protein; Ion Transport 2 Domain Protein

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNTPSSSSGRAGRARRGRKVWSGTQHVIAYGMPPLGWRDLYHHALEVNWPTFFALLATLFLALNAVFAGLYSLGDGAIAN
QSPPGFVGAFFFSVETLATVGYGDMHPQTLYAHVIATLEIFIGMSGIAMATGLVFARFSRPRAKIMFARNVVVRPLNGKS
TLMLRAANARQNVIAEATARLRLMQDEVSPEGYAIYKIHDLKLERSEHPIFLLGWVMMHVIDEASPLHGATAESLAAGDA
LLLLTIEGADETAAQTVQARYSWRHDEIRWNHRYADLIRDESGVTSVDYDNFHLIHPIETPPQAQ

Sequences:

>Translated_305_residues
MNTPSSSSGRAGRARRGRKVWSGTQHVIAYGMPPLGWRDLYHHALEVNWPTFFALLATLFLALNAVFAGLYSLGDGAIAN
QSPPGFVGAFFFSVETLATVGYGDMHPQTLYAHVIATLEIFIGMSGIAMATGLVFARFSRPRAKIMFARNVVVRPLNGKS
TLMLRAANARQNVIAEATARLRLMQDEVSPEGYAIYKIHDLKLERSEHPIFLLGWVMMHVIDEASPLHGATAESLAAGDA
LLLLTIEGADETAAQTVQARYSWRHDEIRWNHRYADLIRDESGVTSVDYDNFHLIHPIETPPQAQ
>Mature_305_residues
MNTPSSSSGRAGRARRGRKVWSGTQHVIAYGMPPLGWRDLYHHALEVNWPTFFALLATLFLALNAVFAGLYSLGDGAIAN
QSPPGFVGAFFFSVETLATVGYGDMHPQTLYAHVIATLEIFIGMSGIAMATGLVFARFSRPRAKIMFARNVVVRPLNGKS
TLMLRAANARQNVIAEATARLRLMQDEVSPEGYAIYKIHDLKLERSEHPIFLLGWVMMHVIDEASPLHGATAESLAAGDA
LLLLTIEGADETAAQTVQARYSWRHDEIRWNHRYADLIRDESGVTSVDYDNFHLIHPIETPPQAQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI303227939, Length=315, Percent_Identity=28.2539682539683, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI4826802, Length=218, Percent_Identity=33.0275229357798, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI23110982, Length=288, Percent_Identity=28.125, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4504839, Length=253, Percent_Identity=30.4347826086957, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI4826798, Length=234, Percent_Identity=32.4786324786325, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI23110984, Length=234, Percent_Identity=32.4786324786325, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI25121970, Length=230, Percent_Identity=33.0434782608696, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4504835, Length=287, Percent_Identity=27.1777003484321, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI24497471, Length=291, Percent_Identity=28.1786941580756, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI148539892, Length=291, Percent_Identity=28.1786941580756, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI24497467, Length=291, Percent_Identity=28.1786941580756, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI24497473, Length=291, Percent_Identity=28.1786941580756, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4504837, Length=291, Percent_Identity=28.1786941580756, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI25777635, Length=323, Percent_Identity=29.4117647058824, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI7019439, Length=323, Percent_Identity=29.4117647058824, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI239751249, Length=288, Percent_Identity=26.3888888888889, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI310117729, Length=288, Percent_Identity=26.3888888888889, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI24797141, Length=291, Percent_Identity=26.8041237113402, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI62388888, Length=287, Percent_Identity=27.5261324041812, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI4504843, Length=229, Percent_Identity=28.82096069869, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI261399884, Length=227, Percent_Identity=30.3964757709251, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI25777640, Length=300, Percent_Identity=27.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI25777638, Length=300, Percent_Identity=27.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI21361127, Length=300, Percent_Identity=27.6666666666667, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI25121966, Length=297, Percent_Identity=27.6094276094276, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI8923823, Length=270, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI25777630, Length=270, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI25777628, Length=270, Percent_Identity=24.4444444444444, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI156119627, Length=298, Percent_Identity=25.503355704698, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI289547204, Length=237, Percent_Identity=26.5822784810127, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17568583, Length=290, Percent_Identity=29.6551724137931, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17568581, Length=290, Percent_Identity=26.2068965517241, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71993162, Length=266, Percent_Identity=28.9473684210526, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24649234, Length=232, Percent_Identity=29.3103448275862, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281362353, Length=232, Percent_Identity=29.3103448275862, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI161078534, Length=232, Percent_Identity=29.3103448275862, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281362366, Length=229, Percent_Identity=27.5109170305677, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24649327, Length=229, Percent_Identity=27.5109170305677, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24649329, Length=229, Percent_Identity=27.5109170305677, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI62484243, Length=335, Percent_Identity=27.7611940298507, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221476063, Length=230, Percent_Identity=28.695652173913, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 33713; Mature: 33713

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPSSSSGRAGRARRGRKVWSGTQHVIAYGMPPLGWRDLYHHALEVNWPTFFALLATLF
CCCCCCCCCCCCHHHCCCHHHCCCCEEEEECCCCCCHHHHHHHHEECCCHHHHHHHHHHH
LALNAVFAGLYSLGDGAIANQSPPGFVGAFFFSVETLATVGYGDMHPQTLYAHVIATLEI
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
FIGMSGIAMATGLVFARFSRPRAKIMFARNVVVRPLNGKSTLMLRAANARQNVIAEATAR
HHCCCHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCEEEEEECCCHHHHHHHHHHH
LRLMQDEVSPEGYAIYKIHDLKLERSEHPIFLLGWVMMHVIDEASPLHGATAESLAAGDA
HHHHHHHCCCCCEEEEEEEEEEEECCCCCEEHHHHHHHHHHHCCCCCCCCCHHHHCCCCE
LLLLTIEGADETAAQTVQARYSWRHDEIRWNHRYADLIRDESGVTSVDYDNFHLIHPIET
EEEEEEECCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCCCEEECCCCEEEEECCCC
PPQAQ
CCCCC
>Mature Secondary Structure
MNTPSSSSGRAGRARRGRKVWSGTQHVIAYGMPPLGWRDLYHHALEVNWPTFFALLATLF
CCCCCCCCCCCCHHHCCCHHHCCCCEEEEECCCCCCHHHHHHHHEECCCHHHHHHHHHHH
LALNAVFAGLYSLGDGAIANQSPPGFVGAFFFSVETLATVGYGDMHPQTLYAHVIATLEI
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
FIGMSGIAMATGLVFARFSRPRAKIMFARNVVVRPLNGKSTLMLRAANARQNVIAEATAR
HHCCCHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCEEEEEECCCHHHHHHHHHHH
LRLMQDEVSPEGYAIYKIHDLKLERSEHPIFLLGWVMMHVIDEASPLHGATAESLAAGDA
HHHHHHHCCCCCEEEEEEEEEEEECCCCCEEHHHHHHHHHHHCCCCCCCCCHHHHCCCCE
LLLLTIEGADETAAQTVQARYSWRHDEIRWNHRYADLIRDESGVTSVDYDNFHLIHPIET
EEEEEEECCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCCCEEECCCCEEEEECCCC
PPQAQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA